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Medicinus : Jurnal Kedokteran
  • Medicinus : Jurnal Kedokteran
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Published by Universitas Pelita Harapan
ISSN : 19783094     EISSN : 26226995     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Medicinus: Jurnal Kedokteran is an official journal of the Faculty of Medicine, Universitas Pelita Harapan launched in the year 2007. Medicinus is a peer-reviewed and open-access journal that covers basic, translational, or clinical aspects of health and medical science. Medicinus accepts original research articles, review articles, and also interesting case reports. Medicinus: Jurnal Kedokteran is published three times a year in February, June, and October.
Arjuna Subject : -
Articles 429 Documents
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Association Between Cigarette Smoking And Cognitive Function In Stroke Patients Of Siloam Lippo Karawaci Hospital Raspati, Raissa Putri; Gunawan, Pricilla Yani
Medicinus Vol 10, No 3 (2021): June 2021
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v9i1.4191

Abstract

Stroke is cerebrovascular disease, causing deterioration of brain function as a result of cerebral blood flow disruption. Stroke is the third leading cause of death in the world and is considered an important cause of long-term disability and cognitive impairment. Risk factors of stroke are further divided into unmodifiable risk factors and modifiable risk factors, with one of the most common modifiable risk factors of stroke, is cigarette smoking. Besides being one of the risk factors that cause stroke, cigarette smoking is believed to have a role in cognitive impairment. This study aims to obtain information regarding the association between cigarette smoking and cognitive function in stroke patients of Siloam Lippo Karawaci Hospital. This research is an unpaired comparative analytical study with a cross-sectional design. Data sampling was taken by consecutive sampling on 56 stroke patients of Siloam Lippo Karawaci Hospital. Cognitive function was made based on the Montreal Cognitive Assessment version Indonesia (MoCA-INA). All data were analyzed by Chi-Square test using SPSS version 25 and the result is considered significant if the p-value < 0,05. From the result of this study. There is a significant association between cigarette smoking and cognitive function (p-value 0,004 and OR 5,343).
Association Between Quality Of Sleep With Primary Headache In Siloam Hospital Karawaci Andriani, Christin; Gunawan, Pricilla Yani
Medicinus Vol 10, No 3 (2021): June 2021
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v9i1.4194

Abstract

A primary headache is the most common neurological complaint and is experienced by almost everyone throughout life.  The most common type of primary headache is TTH (Tension-Type Headache) and Migraine. Quality of sleep is associated with life satisfaction and data shows that one-third of adults are affected by poor sleep. Many studies have mentioned that there is a relationship between quality of sleep and primary headache, but no study has ever been conducted in Siloam Hospital Karawaci. We did a case-control study in Siloam Hospital Karawaci using purposive sampling, with a total of 50 patients as the subjects. Data were collected using the PSQI questionnaire and DASS 42 between January 2019 – March 2019. It was found that there was a significant relationship between sleep quality and primary headache (p= <0,001).
Clinical Spectrum of Neurological Complaints in COVID-19: Experiences from a COVID-19 Referral Hospital in Indonesia Situmeang, Rocksy Fransisca V.; Simanungkalit, Astra Dea; Sutanto, Anyeliria; Pangestu, Aristo
Medicinus Vol 10, No 3 (2021): June 2021
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v9i1.4195

Abstract

Background: The main feature of COVID-19 is symptoms of respiratory system disorder, however, there has been an increase in reports of neurological symptoms that appear in COVID-19 patients. Several previous studies have linked SARS-CoV-2 with nervous system damage. Research studying neurological complaints in  confirmed COVID-19 patients in Indonesia is still lackingAim: To identify neurological, laboratory, and imaging findings in COVID-19 patients with neurological symptoms.Methods: This study was a cross-sectional observational study conducted at Siloam Hospitals Mampang, a COVID-19 referral hospital in South Jakarta. We analyzed medical records of confirmed COVID-19 patients during the period of April - July 2020. The data collected included demographic data, comorbidities, neurological manifestations, laboratory examinations, and neuroimaging.Results: There were 22 confirmed COVID-19 patients with neurological complaints referred to a neurologist. The mean age of patients was 60.4 (SD 15.8) years. The most common neurological complaints were altered mental status (50%), hemiparesis (27.3%), and tremors (22.7%). More than half of the patients (81.8%) had a comorbid condition or past history related to neurological symptoms. Laboratory examination results showed increased NLR (neutrophil-lymphocyte ratio) (50%), anemia (45.5%), and leukocytosis (40.1%). The most common neuroimaging feature was infarct (50%) in the brain CT scan.Conclusion: The neurological complaints in COVID-19 patients are mostly associated with exacerbation of pre-existing comorbidities as a result of the severe inflammatory process triggered by COVID-19. Further research is needed to establish the mechanism of nervous system dysfunction in COVID-19.
Use Of Panty Liner As A Risk Factor The Occurration Of Abnormal Vaginal Discharge Aurellia, Leviana; Nainggolan, Julita
Medicinus Vol 10, No 3 (2021): June 2021
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v9i1.4196

Abstract

Vaginal discharge or fluor albus is a problem that is often found in women. Daily use of panty liner is a predisposing factor of pathological/abnormal vaginal discharge. This paper reviews the correlation between the use of panty liner and vaginal discharge. The aims of this study were to analyze the effect of daily panty liner use as a risk factor of vaginal discharge. This research is done by using the cross-sectional method. The study population is students of the University of Pelita Harapan in the Faculty of  Nursery. Sample size calculation was done using the categorical comparative analytical formula and a result of 46 samples were obtained for each population. A questionnaire was used in this research. Statistical analysis is done by using the SPSS 22.0 program with the Chi-Square method. Bivariate analysis on 92 respondents revealed that there is a significant association between the usage of a panty liner and abnormal vaginal discharge (p-value <0.05). Based on bivariate analysis panty liner material is not related to abnormal vaginal discharge (p-value >0.05).
Comparison of Post Operative Pain Score between Doppler-Guided Hemorrhoidal Artery Ligation and Recto Anal Repair with Open Hemorrhoidectomy on Internal Hemorrhoid Grade III-IV at Siloam Hospitals Lippo Village Sudirman, Taufik; Kosasih, Joanna Audricia
Medicinus Vol 11, No 1 (2021): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v9i2.4701

Abstract

Background: Hemorrhoids are a common lesion affecting 5% of the general population. Open hemorrhoidectomy has been considered a gold standard. However, this method has a significant score of postoperative pain Because of this side effect, another alternative method to treat hemorrhoids has been invented which can reduce post-operative pain. One of these methods is doppler-guided hemorrhoidal artery ligation and rectoanal repair (DGHAL-RAR). This study aims to know the comparison of the postoperative pain score between doppler-guided hemorrhoidal artery ligation and rectoanal repair compared with open hemorrhoidectomy.Method: The sample population of this study is internal hemorrhoid grade III-IV patients at Siloam Hospitals Lippo Village from 2018-2020. Visual analog scale data are taken from medical records. Sample data is obtained using a consecutive sampling method until 64 samples are met. The data obtained will be processed with the Mann U-Whitney test.Results: Incidence of postoperative pain more than VAS 3 occurred in DGHAL-  RAR and open hemorrhoidectomy is 81,3% and 96,9% with a p-value of 0,104. The average score of Visual Analogue Scale score in DGHAL-RAR and open hemorrhoidectomy are 1,97 and 3,13 with a p-value of 0,001.Conclusion: This study shows that the comparison of pain scores in DGHAL-RAR and open hemorrhoidectomy is not statistically significant. The mean score of the Visual Analogue Scale Score in the DGHAL-RAR group is statistically significantly lower than the mean score in the open hemorrhoidectomy group.
Prevalence of Depression, Anxiety, and Stress Among Indonesian Healthcare Workers During the Covid-19 Pandemic and Its Related Factors Tan, Alexa Ovilia; Angelina, Angelina
Medicinus Vol 11, No 1 (2021): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v9i2.4702

Abstract

Introduction: Healthcare workers are the most vulnerable group to infection and mental-emotional problems due to their professional exposure during the COVID-19 pandemic. The studies about healthcare workers’ mental-emotional problems in Indonesia are still limited. This study aimed to determine the prevalence of depression, anxiety, and stress among Indonesian healthcare workers during the COVID-19 pandemic and its related factorsMethods: This is an analytic cross-sectional study involving Indonesian healthcare workers who were still working during the COVID-19 pandemic. An online-based questionnaire in Google Form, including the Depression Anxiety and Stress Scale – 21 (DASS-21) Questionnaire, was distributed through social media from December 2020 to February 2021. The related factors studied were age, gender, domicile, worktime experience, workplace, type of workers, marital status, comorbidities, and COVID-19 history. Results: A total of 176 respondents were involved in the study, the overall prevalence of mental-emotional problems was 18.75%; with a prevalence of depression was 10.8%, anxiety 12.5%, and stress 12.5%. The incidence of depression was more commonly found in non-functional occupations (OR 4.97; 95% CI 1.00-24.69; p=0.05). The incidence of anxiety was less common in male health workers (OR 0.23; 95% CI 0.08 – 0.66; p=0.007), and nurse occupation (OR 6.41; 95% CI 1.65 – 24.86, p=0.007). The incidence of stress was more commonly found in nurse (OR 8.38; 95% CI 1.49 – 47.13; p=0.014), non-functional (OR 10.17; 95% CI 1.78 – 58.04; p=0.008).Conclusion: Mental emotional problems during the COVID-19 pandemic were common among Indonesian healthcare workers, both the front-liners and non-functional health workers. Gender and type of worker were significantly associated with depression, anxiety, and stress.
Psychometric Properties of the Indonesian Version of Impact of Event Scale-Revised Questionnaire During COVID-19 Pandemic Wijovi, Felix; Kurniawan, Andree; Lugito, Nata Pratama Hardjo; Agung, Fransisca Handy; Cipta, Darien Alfa; Angelina, Stella; Halim, Devina Adella; Jodhinata, Claudia; Orlin, Sisilia; Hamdoyo, Audrey; Evangelista, Nadya Nathalia
Medicinus Vol 11, No 1 (2021): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v9i2.4703

Abstract

Background: COVID-19 is a respiratory infection caused by SARS CoV-2. A health-related disaster may result in a wide range of mental consequences, including PTSD. IES-R is a self-reported instrument, and it corresponds to DSM-IV symptoms of PTSD. However, there were scarce data about the validation of the Indonesian version of IESR.Aim: The purpose of this study was to validate the IES-R in the Indonesian adult population by comprehensively and systematically assessing the epidemiological evidence about PTSS during the COVID-19 pandemic.Methods: This was a cross-sectional study. The IES-R questionnaire was translated from English to Indonesian, back-translated. All health workers were excluded to avoid the biased result. Pearson correlation and Cronbach's alpha coefficients to determine the validity and reliability of the questionnaire.Results: A total of 234 Indonesian-speaking adults completed the survey. The Indonesian IES-R had proven to be a valid (r= 0.756 -0.938, p= 0.000) and reliable (alpha coefficient: 0.858-0.868) measure for PTSS in a sample of Indonesian adults during the COVID-19 pandemic. In addition, the final model which consisted of 3 subscales with 20 items demonstrated acceptable factor loadings.Conclusion: The results of this study suggested IESR is valid and reliable to be used in the Indonesian population especially during pandemics.
The Relationship between the Duration of Online Learning during the COVID-19 Pandemic and Symptoms of Depression in Medical Students of Pelita Harapan University: A Cross Sectional Study Purnomo, Alexander Erick; Rivami, Dwi Savitri
Medicinus Vol 11, No 1 (2021): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v9i2.4705

Abstract

Introduction: The COVID-19 outbreak that started in Wuhan, China in December 2019 has become a global pandemic. The existence of the COVID-19 pandemic has led to a change in the university learning system into online learning. Online learning that occurs during the COVID-19 pandemic can have an indirect impact on the mental health of students, one of which is depression. Depression that occurs in online learning can be affected by the duration of online learning.Aim: This study is conducted to determine the relationship between online learning during the COVID-19 pandemic and symptoms of depression in medical students of Pelita Harapan University.Method: This study used a cross-sectional study to be conducted on 161 students of the Faculty of Medicine, University of Pelita Harapan. Sampling will use the purposive sampling method. Collecting data using a questionnaire about the duration of online learning and using the Patient Health Questionnaire-9 (PHQ-9) for depression symptoms. The results of this study were analyzed using chi-square analysis with data processing using SPSS 26.Results: There were 161 samples that matched the inclusion and exclusion criteria of this study. The majority of the sample was female (52.8%), came from the 2018 class (46.0%), 20 years old (50.3%), residing outside the Greater Jakarta area (57.8%), doing more online learning than 6 hours (57.8%) and experienced mild depression (53.4%). The results showed that there was no significant relationship between the duration of online learning and symptoms of depression (OR 1.273; 95%CI (0.669-2.421); p = 0.565).Conclusion: There was no significant relationship between the duration of online learning and symptoms of depression. Further studies with large samples and randomized sampling are required to minimize biases in future studies. 
A 1-Month-Old Baby with Osteogenesis Imperfecta: A Case Report Juliansen, Andry; Meilyn, Anne; Tampake, Lisa Rehinda
Medicinus Vol 11, No 1 (2021): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v9i2.4706

Abstract

Osteogenesis imperfecta (OI) is a connective tissue formation disorder that is generally characterized by bone fragility, osteopenia, blue sclera, dentinogenesis imperfecta (DI), and hearing loss. This disease occurs due to changes in collagen type 1 that form the basis of bone formation so that bones tend to be thinner and smaller. The bones become weak and easily cracked. OI has been classified by type according to the system based on the mode of inheritance, clinical features, and information from the X-ray. There are four types of osteogenesis imperfecta, namely Type I, Type II, Type III, and Type IV. Health problems are often seen in children and adults who have OI include: short stature, weak tissues, fragile skin, muscle weakness, and loose joints, bleeding, easy bruising, frequent nosebleeds, and tiny amounts of heavy bleeding from the wound, impaired loss of hearing can begin in childhood and affects approximately 50 % of adults, breathing problems, a higher incidence of asthma plus risk for other lung problems, spinal curvature.
Distributions of Breast Cancer Primary Tumor Locations in Indonesian Patients Helenia Putri; Maria A Kristina; Devita Widjaja; Bernard A. Baskoro; Erna Kristiani; Rusli Muljadi
Medicinus Vol 9, No 3 (2021): October 2021-January 2022
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v9i3.4933

Abstract

Introduction: Overseas studies have shown various distributions of breast cancer primary tumor locations based on stages and histopathologic types. Based on them, breast cancer was consistently reported to be found on the left breast more than the right. Breast cancer laterality was estimated to be one of the determinant factors in prognosis. In Indonesia, there are only a few studies on the laterality of breast cancer, as well as the characteristics that accompany it. The aim of this study is to know the distributions of primary breast cancer tumor locations in Indonesian patients.Material and Methods: A cross-sectional design study was done and the data was collected from Siloam Hospital Lippo Village radiology and pathology anatomy department within the 2014-2018 period. The results were presented using descriptive statistics.Results: A total of 74 breast cancer patients from various ages and stages were enrolled in this study. Based on the histopathological types, 84.2% of patients left breast tumors and 72.2% of patients with right breast tumors had invasive ductal carcinoma of no special type. Based on quadrants, 50% of tumors on the left breast are in the superolateral quadrant, followed by 31.6% in superomedial, 13.2% in inferomedial, and the rest in inferolateral. Conclusion: Most tumors are located in the superolateral quadrant and the most histopathological types are non-specific invasive carcinomas.

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