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Journal of Maternal and Child Health
Published by Universitas Sebelas Maret
ISSN : -     EISSN : 25490257     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Journal of Maternal and Child Health (JMCH) is an electronic, open-access, double-blind and peer-reviewed international journal, focusing on maternal and child health. The journal began its publication on July 11, 2015, and is published four times yearly. JMCH aims to improve the policy, program, service, and practice, as they impact infant, children, mother, women, adolescent, and family health.
Arjuna Subject : -
Articles 12 Documents
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Search results for , issue "Vol. 7 No. 3 (2022)" : 12 Documents clear
Expression of Bax Protein as A Prognosis Factor of Radiotherapy Response to Decreased Tumor Size in Stage IIB-IIIB Cervical Cancer Fitriawan, Ahmad; Udiyanto, Hermawan; Respati, Supriyadi Hari; Ratnasari, Affi Angelia; Prabowo, Wisnu
Journal of Maternal and Child Health Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (35.074 KB) | DOI: 10.26911/thejmch.2022.07.03.07

Abstract

Background: Cervical cancer plays a role as the leading cause of cancer death for women in developing countries. Radiation therapy kills cancer cells through double strand breaks and the apoptotic process. Bax protein is one of the regulators of apoptosis. This study analyzed the role of Bax expression as a prognostic factor in radiation therapy response in reducing tumor size in patients with advanced cervical cancer (IIB-IIIB). Subjects and Method: This research is a retrospective cohort observational analytic study from January 2021 to April 2021 in the Department of Obstetrics and Gynecology in collaboration with the Department of Anatomical Pathology, Dr. Moewardi Hospital, Surakarta, Indonesia. This study involved 30 cervical cancer stage IIB-IIIB patients. The level of Bax expression was determined by immunohistochemical examination. ROC curve analysis was used to find cut-off points and evaluate the sensitivity and specificity of Bax in the prognosis of radiotherapy in patients with advanced cervical cancer (IIB-IIIB). Chi square test was used to determine the relationship between Bax expression and changes in tumor size in cervical cancer patients. Results: The ROC curve analysis showed that the AUC Bax score in prognosis of radiation therapy was 0.575 (CI 95%= 0.32 to 0.83) and the cutoff point was 62.5%. Based on the analysis of the ROC curve, the Bax expression of 62.5% shows a sensitivity of 56.5% and a specificity of 71.4%. Analysis of the relationship between Bax protein expression on changes in tumor size using the Chi Square test showed a P value of 0.390 (p> 0.05). Conclusion: The expression of Bax protein cannot play a role as a prognostic factor in the response of radiation therapy to the reduction in tumor size in stage IIB-IIIB uterine cervical cancer.
Meta-Analysis: The Effectiveness of Using mHealth to Improve Antenatal Care Kartikasari, Mayriyana; Tamtomo, Didik; Murti, Bhisma
Journal of Maternal and Child Health Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (33.697 KB) | DOI: 10.26911/thejmch.2022.07.03.12

Abstract

Background: One of the innovations in technology in health that can be used is mHealth. The use of technology such as mHealth allows for the dissemination of information to pregnant women in an effort to improve antenatal care. This study aims to determine the effectiveness of using mHealth on antenatal care. Subjects and Method: This was a systematic review and meta-analysis study using PICO, Population: Pregnant women, Intervention: Using mHealth, Com­parison: Not using mHealth/ standard services, Outcome: ANC visits. The articles used in this study came from 6 databases including Pubmed, ScienceDirect, Google Scholar, BMJ, Springer link, Sage, and Core. The keywords of the article are, Telemedicine OR Mobile Health OR Health Mobile OR Telehealth OR mHealth OR eHealth AND Short Message AND Quality Improvement OR Quality Improvement OR Quality Improvements OR Quality Improvements AND Prenatal Care OR Prenatal Care OR Antenatal Care OR Antenatal Care. The articles included in this study are complete articles, RCT study designs for 2012-2022. Results: There are 8 RCT articles from 3 continents, including Africa (Kenya, Ethiopia, Zanzibar), Asia (India), America (Peru, Brazil). It was found that using mHealth could increase ANC visits by 1.32 times compared to not using mHealth (RR=1.32; 95% CI=1.10 to 1.59; p=0.003). Conclusion: effective use of mHealth to improve antenatal care.

Page 2 of 2 | Total Record : 12

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