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All Journal Journal of Maternal and Child Health Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya Shift Key: Jurnal Teologi dan Pengembangan Pelayanan MAGNUM OPUS: Jurnal Teologi dan Kepemimpinan Kristen Journal of Pharmaceuticals and Natural Sciences Shine : Jurnal Bimbingan dan Konseling Folia Medica Indonesiana

WISNU PRABOWO

STMIK AMIKOM Yogyakarta

Author-ID : 343694

Religion Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Articles

Menerapkan Prinsip 2 Timotius 1:7 dalam Pelayanan Penginjilan Prabowo, Wisnu
MAGNUM OPUS: Jurnal Teologi dan Kepemimpinan Kristen Vol 1, No 1 (2019): Desember 2019
Publisher : Sekolah Tinggi Teologi IKAT Jakarta

As God's creation, humans are given spirits by God; the spirit has various functions and uses in life. In 2 Timothy 1: 7 it is written about the spirit of fear, a spirit that awakens strength, love and order. This article examines the meaning of "the spirit of fear, the spirit that awakens strength, love and order" in 2 Timothy 1: 7. This study is a qualitative study using descriptive methods of literature and text analysis. The results obtained are: First, God never gave a spirit that made the servants of God afraid in preaching the Gospel, but God gave a spirit that was able to have strength, love and self-control. So that, despite pressure and obstacles, God's servant is still able to carry out and finish his ministry in preaching the gospel. Abstract Sebagai ciptaan Allah, manusia diberikan roh oleh Allah; roh tersebut mempunyai berbagai fungsi dan juga kegunaan di dalam kehidupan. Di dalam 2 Timotius 1:7 tertulis tentang roh ketakutan, roh yang membangkitkan kekuatan, kasih dan ketertiban. Artikel ini mengkaji arti dari ungkapn â€œroh ketakutan, roh yang membangkitkan kekuatan, kasih dan ketertibanâ€ dalam 2 Timotius 1:7 tersebut. Kajian ini merupakan penelitian kualitatif yang menggunakan metode deskriptif literatur dan analisis teks. Hasil yang diperoleh adalah: Pertama, Tuhan tidak pernah memberikan roh yang menjadikan para pelayan Tuhan takut di dalam memberitakan Injil, namun Tuhan memberikan roh yang memampukan untuk mempunyai kekuatan, kasih dan penguasaan diri. Sehingga, walaupun mendapatkan tekanan dan hambatan, pelayan Tuhan tetap mampu melaksanakan dan menyelesaiakan pelayanannya dalam memberitakan Injil.

Enhancing Nutrients Knowledge during Pregnancy through Webinars to Prevent Stunting Bachnas, Muhammad Adrianes; Sulistyowati, Sri; Yuliantara, Eric Edwin; Anggraini, Nutria Widya Purna; Prabowo, Wisnu; Respati, Supriyadi Hari; Nurinasari, Hafi; Ridwan, Robert; Astetri, Lini; Yuliani, Saffana Oka; Carissa, Dinda; Alamsyah, Meuthia
Journal of Maternal and Child Health Vol. 7 No. 5 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: Indonesia still has a high stunting rate, 1.2 million out of 5 million births each year result in stunted baby growth. linear growth in utero, the process can be caused by maternal malnutrition, which can result in intrauterine growth inhibition and low birth weight, and result in stunting. This study aims to analyze the effectiveness of the webinar in improving nutrition knowledge during pregnancy to prevent stunting growth. Subjects and Method: This is a cross sectional study conducted in July, 15th 2022 using the Zoom Meeting webinar platform. Target population are all young POGI and POGI Members who took part in webinars and online conversations using the Zoom Meeting program. This study used random sampling, and sample size are 161. The independent variables of this study was learning via webinars while the dependent variable was nutrient knowledge. Data were analyzed by paired t-test statistical test. Results: There was a significant difference score of knowledge in pregnant women after (Mean= 8.60) compared to before webinars (Mean= 6.52). Conclusion: The result of this study indicates that learning method via webinars increased maternal understanding about optimal nutrient during pregnancy. Keywords: stunting, nutrients, webinar, pregnant women Correspondence: Nutria Widya Purna Anggraini. Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sebelas Maret/Dr. Moewardi General Hospital, Surakarta, Central Java, Indonesia. Jl. Kolonel Sutarto No. 132 Jebres, Surakarta. Email: nutria_dr@staff.uns.ac.id. Mobile: 08122651819.

The Effect of Recombinant Vascular Endothelial Growth Factor (VEGF)-121 Towards Placenta Growth Factor Serum Levels in Female Mice (Mus Musculus) with Preeclampsia Model Prabowo, Wisnu
Journal of Maternal and Child Health Vol. 6 No. 3 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: Preeclampsia is a multi systemic disease which recognized by the development of hypertension after 20 weeks of gestation with the presence of proteinuria or any signs indicative of target organ injury. The correct diagnosis and classification of the disease are essential since the therapies are unique in each class. Moreover, the angiogenic factors claims to play a significant role in the endothelial injury which plays as an etiology for preeclampsia. Thus, this study aimed to analyze the differences between angiogenic factors in pregnancy mice with preeclampsia models after administration of VEGF-121. Subjects and Method: Subject of the study were swiss’s strains of pregnancy mice (Mus musculus) which divided into three groups that consist of 10 subject of study in each group. Subjects for this research were recruited between March and May 2015 in Biomedical Laboratory of The Faculty of Veterinary Medicine, Universitas Airlangga as part of a cross sectional study designed for analytical experimental. The angiogenic factor which measured was PIGF serum levels with ELISA method and only group of pregnant mice with preeclampsia model which administred with injection of VEGF-121. Results: This study was conducted of 30 male and 30 female Mus musculus with homogeneous characteristic in terms of age, average body weight and have never been pregnant before. The differences in PIGF serum levels between three observed group are significant (p=0.035). Conclusion: Administration of VEGF-121 increased the PlGF serum levels in pregnant mice with preeclampsia model. Thus, the administration of VEGF-121 improves the condition of endothelial damage in preeclampsia with an increase in PlGF levels.

Expression of Bax Protein as A Prognosis Factor of Radiotherapy Response to Decreased Tumor Size in Stage IIB-IIIB Cervical Cancer Fitriawan, Ahmad; Udiyanto, Hermawan; Respati, Supriyadi Hari; Ratnasari, Affi Angelia; Prabowo, Wisnu
Journal of Maternal and Child Health Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Background: Cervical cancer plays a role as the leading cause of cancer death for women in developing countries. Radiation therapy kills cancer cells through double strand breaks and the apoptotic process. Bax protein is one of the regulators of apoptosis. This study analyzed the role of Bax expression as a prognostic factor in radiation therapy response in reducing tumor size in patients with advanced cervical cancer (IIB-IIIB). Subjects and Method: This research is a retrospective cohort observational analytic study from January 2021 to April 2021 in the Department of Obstetrics and Gynecology in collaboration with the Department of Anatomical Pathology, Dr. Moewardi Hospital, Surakarta, Indonesia. This study involved 30 cervical cancer stage IIB-IIIB patients. The level of Bax expression was determined by immunohistochemical examination. ROC curve analysis was used to find cut-off points and evaluate the sensitivity and specificity of Bax in the prognosis of radiotherapy in patients with advanced cervical cancer (IIB-IIIB). Chi square test was used to determine the relationship between Bax expression and changes in tumor size in cervical cancer patients. Results: The ROC curve analysis showed that the AUC Bax score in prognosis of radiation therapy was 0.575 (CI 95%= 0.32 to 0.83) and the cutoff point was 62.5%. Based on the analysis of the ROC curve, the Bax expression of 62.5% shows a sensitivity of 56.5% and a specificity of 71.4%. Analysis of the relationship between Bax protein expression on changes in tumor size using the Chi Square test showed a P value of 0.390 (p> 0.05). Conclusion: The expression of Bax protein cannot play a role as a prognostic factor in the response of radiation therapy to the reduction in tumor size in stage IIB-IIIB uterine cervical cancer.

DASAR ALKITABIAH MENERIMA IBADAH ONLINE MENURUT FILIPI 3:3 Prabowo, Wisnu
Shift Key : Jurnal Teologi dan Pelayanan Vol. 11 No. 2 (2021): Regular Issue, Volume 11 Number 2 (2021)
Publisher : P3M STT Kristus Alfa Omega

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37465/shiftkey.v11i2.195

In the life of a Christian, the Holy Spirit has a very important role. In every detail of their lives, Christians believe that the Holy Spirit directs and guides them. Worship of God by Christians includes those directed and guided by the Holy Spirit. But there are still Christians who prioritize and think about external or worldly things as the main requirement to be able to worship God. Nowadays, worship is mostly done with online worship procedures. However, online worship gets a less religious impression when compared to worship that is carried out in person in a church building. The Apostle Paul emphasized in Philippians 3:3 that every Christian can worship only because of God's grace and also because of the guidance of the Holy Spirit. Christians should no longer depend on external things to come to worship God. This study is a qualitative research using inductive exegesis research methods and bibliography. This study examines the phrase â€œwho worship God in the Spiritâ€ found in Philippians 3:3. The results of the study obtained are: First, Christians experience very strong pressure and temptation to think about external things in worshiping God. Second, Christians must prioritize a spiritual life led by the Holy Spirit in their worship of God, because worship is a gift from God. Both of these results prove that worship carried out using online procedures has the same religious value as worship carried out in church buildings.

Pharmacognosic Study and Determination of Marker Compounds Soursop Leaves (Annona muricata) M. Arifuddin; Faisal, Muhammad; Samsul, Erwin; Hikmawan, Baso Didik; Prabowo, Wisnu; Ahmad, Islamudin; Ibrahim, Arsyik
Journal of Pharmaceuticals and Natural Sciences Vol. 1 No. 1 (2024): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/zjthbv92

Soursop (Annona muricata) is reported to have great efficacy in traditional medicine in Indonesia so it is very vulnerable to being faked or sold as low quality. Apart from having a delicious fruit taste, Soursop leaves have also been used as an effective cancer medicine by the public and have been scientifically proven so that Soursop can be used as a phytopharmaceutical product. Therefore, it is necessary to carry out research to determine pharmacognosy parameters and marker compounds as ingredients needed to obtain the authenticity of simplicia and plant extracts. This research includes macroscopic and microscopic examination of leaves, macroscopic and microscopic examination of simplicia, fluorescence characteristics of simplicia, determining the solubility of methanol extract in various non-polar and polar solvents as well as the characteristics of marker compounds that can be used as alternatives to existing marker compounds from Soursop (Annona muricata). The research results obtained are important information as a stage for the identification and standardization of soursop leaves (Annona muricata) as a raw material for herbal medicine.

Efektivitas Bimbingan Kelompok Teknik Home Room Untuk Mencegah Dampak Negatif Berpacaran Di Smk Pgri 1 Kudus slamet, agung; Prabowo, Wisnu; Hidayati, Richma
SHINE: JURNAL BIMBINGAN DAN KONSELING Vol. 6 No. 1 (2025)
Publisher : STKIP PGRI SUMENEP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36379/shine.v6i1.989

The objectives of this study are: 1. To determine the improvement of students' understanding before and after being given Homeroom engineering group guidance services to students in grade X MPLB 3 SMK PGRI 1 Mejobo Kudus., 2. To find out the effectiveness of the implementation of homeroom engineering group guidance services to prevent the negative impact of dating on students by using Group Guidance. The research uses the quasi-experiment method of design one group pretest and posttest. This research was carried out in class X MPLB 3 by conducting a pretest to find out the number of research subjects needed for treatment and after the pretest was carried out. The results of the study showed that before group guidance with the homeroom technique (pretest) the understanding of the negative impact of dating tended to be low with an average of 71.5 and after being given the treatment of group guidance services with the homeroom technique (posttest) the understanding of the negative impact of dating experienced a significant increase.

Hypoxia Inducible Factor-1-Alpha Expression on Preeclampsia Mice Model With L-Arginine Administration Anggraini, Nutria Widya Purna; Sulistyowati, Sri; Bachnas, Muhammad Adrianes; Yuliantara, Eric Edwin; Prabowo, Wisnu; Budihastuti, Uki Retno
Folia Medica Indonesiana Vol. 57, No. 3
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Preeclampsia is hypertension in pregnancy that aï¬€ects 2% to 8% of pregnancies worldwide and causes significant maternal and perinatal morbidity and mortality. In the pathogenesis of preeclampsia, placental hypoxia plays an important role, associated with excessive trophoblast apoptosis resulting in decreased trophoblast and spiral arteries invasion. This placental hypoxic condition will induce increased expression of Hypoxia Inducible Factor -1-Alpha (HIF-1-A). L-Arginine is a potent vasodilator presumably to improve preeclampsia placental hypoxic conditions and reduce HIF-1-A expression. This study was an experimental study with a parallel-group post-test only design. Thirty-six preeclamptic mice models were divided into 2 groups. The control group (K1) 18 preeclamptic mice model without treatment and the treatment group (K2) 18 preeclamptic mice given L-Arginine. The independent variable was the administration of L-Arginine and the dependent variable is the placental HIF-1-A expression. Statistical analysis used unpaired t-test on normal data distribution, and Mann Whitney test on abnormal data distribution. The mean of placental HIF-1-A expression K1 was 2.47 ± 1.65 with a minimum value of 0.4 and a maximum value of 6.6. At K2 0.93 ± 0.55 with a minimum value of 0.0 and a maximum value of 2.0. Statistical tests showed that the placental HIF-1-A expression in the treatment group was significantly lower than that in the control group (p <0.001). In conclusion, the expression of HIF-1-A in preeclamptic mice model placenta decreased with L-Arginine administration.

LEARNING TO PREVENT AND BREAK THE CHAIN OF TRANSMISSION OF COVID-19 BY VACCINATE WOMEN, PREGNANT AND BREASTFEEDING MOTHERS THROUGH THE WEBINAR Bachnas, Muhammad Adrianes; Anggraini, Nutria Widya purna; Sulistyowati, Sri; Yuliantara, Eric Edwin; Prabowo, Wisnu; Nugraha, Gagah B Adi; Firmansyah, Aldi; Prameilita, Dympna
Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya Vol 10, No 1 (2022): February
Publisher : Program Studi Kebidanan Fakultas Kedokteran Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/placentum.v10i1.52880

Background: The incidence of Covid-19 in women, pregnant, and breastfeeding mothers is still high. Currently, the government is trying to prevent and break the chain of Covid-19 transmission by vaccination. However, knowledge about Covid-19 vaccination is still limited. Therefore, Indonesian Obstetrics and Gynecology Association/Perkumpulan Obstetri dan Ginekologi Indonesia (POGI) members, as the spearhead of women's health, play an essential role in breaking the chain of transmission by providing knowledge about Covid-19 vaccination.Methods: All member of POGI and Youth POGI in Surakarta was educated by online method via the webinar zoom application. The level of knowledge was evaluated pre and post-webinar by using a questionnaire to see the significance.Result: Analysis of 110 participants with paired t-test obtained an average pretest value of 44.82 while the average post-test value was 57.45, with a significance value of p=0.001 (p<0.05). The results of the analysis with the Chi-square test obtained p = 0.002 (p <0.05) and OR = 23.40.Conclusion: There is an increased understanding of preventing and breaking the chain of transmission of Covid-19 in women, pregnant, and breastfeeding mothers by vaccinating youth POGI and POGI members after webinar and discussion, with a significance value of p=0.001 (p<0.05). Webinars and discussions on preventing and breaking the chain of transmission of Covid-19 to women, pregnant, and breastfeeding mothers with vaccination by researchers provided 23.40 times better understanding than before the webinar and discussions were given.

Early Detection and Good Team Collaboration for Preventing Maternal Death Caused by Placenta Accreta Spectrum Disorder Yuliantara, Eric Edwin; Bachnas, Muhammad Adrianes; Anggraini, Nutria Widya Purna; Prabowo, Wisnu; Nugraha, Gagah Baskara Adi; Chasanah, Meriska Dewi; Alim, Fadel Muhammad S.; Merina, Hikmah F.
Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya Vol 11, No 2 (2023): August
Publisher : Program Studi Kebidanan Fakultas Kedokteran Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/placentum.v11i2.71047

Background: Placenta accreta spectrum (PAS) is considered one of the most harmful pregnancy conditions, as it is strongly linked with maternal morbidity and mortality. An accurate and early prenatal diagnosis of PAS allows time for a multidisciplinary team to plan the best course of action for delivery management. The aim of this study is to describe placenta accreta spectrum management and outcomes with early detection and a multidisciplinary team approach.Method: A retrospective cohort study was conducted on 167 cases of placenta accreta from 2016 to 2021. Medical records were then reviewed, and data were collected for delivery management and maternal outcome, including estimated amounts of bleeding, urinary tract injury, delivery time, ICU referral, and maternal death.Result: Delivery management (hysterectomy and conservative management) and maternal bleeding were significantly associated with MAP score (p < 0.05), while urinary tract injury, delivery time, ICU admission, and maternal death were not significantly associated (p > 0.05). 55.1% of patients underwent hysterectomy, and the rest 44.9% underwent conservative surgery. Massive bleeding of more than 2500 mL happened in 54.5% of patients, and the rest 45.5% managed to bleed less than 45.5%. Preterm deliveries accounted for 29.9% of all deliveries, with the remaining 70.1% being term. 5.4% of patients experienced urinary tract injuries. 6.6% of patients were referred to the intensive care unit. The maternal mortality rate is 4.8%.Conclusion: Early detection of the placenta accreta spectrum, as well as good collaboration among members of a multidisciplinary team from various medical fields, are required to ensure the mother and baby's safety and survival.

Co-Authors Alamsyah, Meuthia Alim, Fadel Muhammad S. Astetri, Lini Bachnas, Muhammad Adrianes Baso Didik Hikmawan Carissa, Dinda Chasanah, Meriska Dewi Eric Edwin Yuliantara Erwin Samsul Firmansyah, Aldi Fitriawan, Ahmad Hermawan Udiyanto Ibrahim, Arsyik Islamudin Ahmad M. Arifuddin Merina, Hikmah F. Muhammad Faisal Nugraha, Gagah B Adi Nugraha, Gagah Baskara Adi Nurinasari, Hafi Nutria Widya Purna Anggraini Prameilita, Dympna Ratnasari, Affi Angelia Richma Hidayati Ridwan, Robert Slamet, Agung Sri Sulistyowati Supriyadi Hari Respati Uki Retno Budihastuti Yuliani, Saffana Oka

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