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Jurnal Farmasi Higea

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Published by Sekolah Tinggi Ilmu Farmasi Padang

ISSN : - EISSN : 25413554 DOI : -

Core Subject : Health,

Medicine & Pharmacology

Arjuna Subject : -

Articles 10 Documents

Search results for , issue "Vol 5, No 2 (2013)" : 10 Documents clear

Penentuan Cemaran Mikroba Pada Jamu Pelangsing Yang Beredar Di Pasar Tarandam Padang Rina Wahyuni; Vonda Perdana Lase; Harrizul Rivai
Jurnal Farmasi Higea Vol 5, No 2 (2013)
Publisher : STIFARM Padang

Research about microbial countamination on slimming herbals powders, pills, capsules and caplets circulating in Tarandam market, Padang, has been evaluated. Powders had total plate count 0 x 106 CFU/g for PP (standard quality of powder was ≤ 1 x 106 CFU/g for total plate count). Pills had total plate count ≤ 0.5 x 105 CFU/g for MR (standard quality of pill was ≤ 1 x 105 CFU/g for total plate count). Capsules had total plate count 1.1 x 105 CFU/g for LM and 1.6 x 105 CFU/g for SA (standard quality of capsule was ≤ 1 x 104 CFU/g for total plate count) and Caples had total plate count 0.2 x 105 CFU/g for SC (standard quality of caplet was ≤ 1 x 104 CFU/g for total plate count). The total plate count calculation showed that only powders and pills were observed the BPOM standard quality of herbal drugs.The fungal count from all of samples were not observed the standard quality of herbal drugs. Powders had total fungal count 9 x 104 CFU/g for PP (standard quality of powder was ≤ 1 x 104 CFU/g for total fungal count). Pills had total fungal count 3.1 x 104 CFU/g for MR (standard quality of pill was ≤ 1 x 103 CFU/g for total fungal count). Capsules had total fungal count 2,3 x 104 CFU/g for LM and 2.6 x 104 CFU/g for SA (standard quality of capsule was ≤ 1 x 103 CFU/g for total fungal count) and caplets had total fungal count 2.1 x 104 CFU/g for SC (standard quality of caplet was ≤ 1 x 103 CFU/g for total fungal count).

Karakterisasi Ekstrak Herba Meniran (Phyllanthus niruri Linn) Dengan Analisa Fluoresensi Harrizul Rivai; Refilia Septika; Agusri Boestari
Jurnal Farmasi Higea Vol 5, No 2 (2013)
Publisher : STIFARM Padang

Have done the manufacture and characterization of thick herba extracts meniran (Phyllanthus niruri Linn). Condensed extract is made using 96% ethanol solvent was concentreated by rotary evapolator. The observed character of the extract that is by fluorescence analysis. Fluorescence analysis performed on each fraction, methanol fraction, ethyl acetat fraction the fraction of water, kloroforom fraction, eter fraction in the test under UV 254 nm and 366 nm UV light whit the addition of reagents. The results obtained from the fraction of a significant color reaction is positive alkaloid characterized by a bright green color under UV light 254 nm, positive light yellow flavonoid under 366 nm UV lamp. In this study also tested the physic chemical.

Kajian Efek Stimulan Dari Beberapa Minuman Energi Kemasan Sachet Yang Beredar Di Pasaran Zet Rizal; Candra Syuryani; Helmi Arifin
Jurnal Farmasi Higea Vol 5, No 2 (2013)
Publisher : STIFARM Padang

A research of some sachet energy drinks on the market on the activity of the central nervous system stimulant for white mice (Mus musculus, L.) has been done. The samples labelled Minuman Energi Sachet MES 1, MES 2, MES 3, MES 4 and MES 5 and administered perorally. Parameters used for stimulant activity were endurance tested using Rotary road, while motoric activity and curiosity tested using Automatic Hole Board. Each sample has administration volume of 0.52 ml/20 g BW. Comparator ued is caffeine 0.13 mg/ 20 g BW. From the research that has been done, it is known that MES 1, MES 2, MES 3, MES 4 and MES 5 has a central nervous system stimulant activity by increasing endurance, motoric activity and curiosity in mice significantly.

Penetapan Kadar Kofein Daun Kopi Kawa ( Coffea Robusta ,Lind ) Roslinda Rasyid; Winaldi Fitra Sanjaya; Zulharmita Zulharmita
Jurnal Farmasi Higea Vol 5, No 2 (2013)
Publisher : STIFARM Padang

Research has been done on the determination of caffeine that leaves Kawa Coffee ( Coffea robusta Linden ex DE Wildem ) by using Soxlhetation method. Coffein from extraction purified by preparative TLC mobile phase solution chloroform : methanol ( 9:1 ).The constration of pure Coffein from preparative TLC has been determinedby using Spectrophotometer Uv-Vis T -70 .The result Coffea Kawa leaves (Coffea robusta Limden ex De Wildem ) is 0.7 % w/w

Pembuatan Kalsium Karbonat Dari Batu Kapur Bukit Tui Kota Padang Panjang Rusdi Rusdi; Metalia Maryesri; Zulharmitta Zulharmitta
Jurnal Farmasi Higea Vol 5, No 2 (2013)
Publisher : STIFARM Padang

A Research has been done about preparing calcium carbonat from limestone of Bukit Tui Kota Padang Panjang. The sample as much as 20 g was dissolved in HCl 6 M, the resulting filtrate reacted with NH4OH 6 M to the pH of 8 and reacted with (NH4)2CO3 6 M until no more precipitate was was formed. The precipitate was separated and dried in oven for 4 hours at 105º C. Ten g of the dried precipitate was determined complexometrically using EDTA as complexson and murexide as indicator. It was found that the limestone at Bukit Tui Kota Padang Panjang contained 67.2 % w/w calcium carbonate in comparison to reference compound 103.99 % w/w.

Penggunaan Biopolimer Polikaprolakton Sebagai Matrik Herbisida Lepas Lambat Asam 2,4-Diklofenoksi Asetat Akmal Djamaan; Yutra Noka; Netty Suharty
Jurnal Farmasi Higea Vol 5, No 2 (2013)
Publisher : STIFARM Padang

The study on 2,4-Dichlorophenoxyacetic acid (2,4-D) microencapsulation by solvent evaporation method using polycaprolactone (PCL) as a polimer has been done. The monitored of data how the effect release of substance active toward coated during 480 minutes. From the result of disolution gave rapid disolution of microcapsulation 2,4-D higher at formula 2 rather than formula 1 and 3. This show thickly upholstry of PCL have an effect on to release of substance active. Kinetics method release of substance active of microcapsule 2,4-D following order zero, first order and equation of Higuchi.

Uji Sistem Dispersi Padat Kofein Dengan Menggunakan Polivinil Pirolidon (PVP) K-30 Maria Dona Octavia; Auzal Halim; Sari Kartika
Jurnal Farmasi Higea Vol 5, No 2 (2013)
Publisher : STIFARM Padang

The research about solid dispersion test of coffein used Polvinil pyrrolidone (PVP) K-30. In the current study using solid dispersion coffein using Polyvinyl pyrrolidone (PVP) K-30 and a mixture of physics. coffein manufacture solid dispersion using Polyvinyl pyrrolidone (PVP) K-30's, using the method of dissolution. The parameters tested were melting range, lift angle, specific gravity, Hausner factor, compressibility, porosity, water content, particle size distribution, the absorption of water, microscopic analysis and dissolution. Result of research coffein solid dispersion system using Polyvinyl pyrrolidone (PVP) K-30 can increase the solubility Kofein compared with the mixed form of physics. The percent of dissolution of the best in the 35th minute was the solid dispersion formula 4: 6, amounting to 79.34% compared with other formula.

Peningkatan Laju Disolusi Sistem Dispersi Padat Ibuprofen – PEG 6000 Auzal Halim; Elvi Rahma Yulisman; Erizal Zaini
Jurnal Farmasi Higea Vol 5, No 2 (2013)
Publisher : STIFARM Padang

It has done research on increasing the dissolution rate of solid dispersion system Ibuprofen with polymer Polyethylenglycols 6000 (PEG 6000). Solid dispersion system prepared by melting method with a ratio of raw materials Ibuprofen - PEG 6000, namely : 6:4, 7:3, 8:2, and 9:1. As a comparison was made with the physical mixture of the same composition. The powder mixture of physics and solid dispersion system properties of solids characterized by spectroscopic analysis, SEM analysis, DTA analysis, and X-ray diffraction analysis. Dissolution test method is determined by a basket. The results showed that the powder solid dispersion system can improve the physicochemical properties of Ibuprofen. Dissolution profiles showed that the 7:3 solid dispersion system powder in the 45th minute to increase the dissolution rate compared to the powder mixture of physics.

Pengaruh Pemberian Ekstrak Etanol Daun Patikan Kebo (Euphorbia Hirta L.) Terhadap Kadar Ldl Pada Mencit Putih Jantan Surya Dharma; Hendri Fatriona; Elisma Elisma
Jurnal Farmasi Higea Vol 5, No 2 (2013)
Publisher : STIFARM Padang

Study about the influence of Euphorbia hirta L. leaves’s aethanolic extract on the levels of blood LDL in white male mice has been done. The aethanolic extract of Euphorbia hirta L. was given orally once a day for 7 th, 14 th and 21 th days.The doses used were 2, 6, 18 mg/ 20g body weight respectively. Control group was given standard food. Parameter was measured level of blood LDL. The result show that the aethanolic extract of Euphorbia hirta L. does not influence to the levels of LDL, while the time factor for 7 th, 14 th and 21 th days showed a significant effect (p <0.05).

Uji Efek Anti Anafilaksis Kutan Aktif Dari Ekstrak Etanol Daun Ketepeng Cina (Cassia Alata L.) Pada Mencit Putih Jantan Yufri Aldi; Yaser Arafat; Zet Rizal
Jurnal Farmasi Higea Vol 5, No 2 (2013)
Publisher : STIFARM Padang

An assay of the active cutaneous anti anaphylactic of the ethanolic extract of the Cassia alata L. On male white mice has been studied. The assay was done by giving three different doses (100,300, 900 mg per kg body weight ). Allergic reaction was induced by giving egg’s albumin as antigen. The anti anaphylactic effect was determined by measurement of the pro long of occurrence time, the dereased in diameter and the color intensity of the blue bump formed by using blue evan’s solution as indicator which was given intravenously. Result indicated the ethanolic extract of Cassia alata L. (100, 300, 900 mg per kg body weight ) had significant effect for each dose (p<0.05). The dose of 900 mg per kg body weight showed best effect.

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