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Dina Keumala Sari
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Jl. Dr. T. Mansur No. 9 Padang Bulan, Kecamatan Medan Baru, Kota medan, Sumatera Utara, Indonesia
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INDONESIA
Sumatera Medical Journal
Published by Universitas Sumatera Utara
ISSN : 26229234     EISSN : 26221357     DOI : 10.32734
Core Subject : Health, Science,
Immunology & microbiology Medicine & Pharmacology
Sumatera Medical Journal (SUMEJ) provides a forum for publishing the full research articles in the area of Medical Science related to topics from the following subject areas: -Cancer and Related Aspects -Biomoleculer in Basic Sciences -Biomoleculer in Clinical Sciences -Tissue Engineering including Stem Cell -Medical and Health Sciences
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 169 Documents
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Breast Cancer Clinicopathology based on Neutrophil Levels at Adam Malik Hospital Medan in 2018-2021 Mario Saragih , Tonggo; Hermansyah, Dedy; Rifsal Siregar , Denny; Aprillia Ariestine, Dina
Sumatera Medical Journal Vol. 7 No. 1 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i1.10946

Abstract

Background: Breast cancer is the most frequently diagnosed cancer in the world. Breast cancer occurs due to abnormal cell growth in breast tissue so that it becomes malignant. In Indonesia, breast cancer is the most common cancer in women. That way, many markers are needed as prognostic and predictive of breast cancer. One of the prognostic factors for breast cancer is neutrophil levels combined with clinicopathological factors. Objective: Knowing the clinicopathology of breast cancer based on neutrophil levels at the Adam Malik Medan General Hospital in 2018-2021. Methods: The research design is observational with a descriptive method and calculated using the Lemeshow formula. Results: Majority aged 40-49 years (39.6%), high school (44.8%), housewives (67.7%), no family history (97.9%), tumor grade II (38.5%) %), Tumor Infiltrating Lymphocytes (TILs) severe (47.9 %), mitotic score 1 (38.5 %), metastatic positive lymph node status (87.5 %), tumor size T1 (36.5 %), The number of positive and negative Estrogen Receptors is the same (50.0%), Progesterone Receptor is negative (56.3%), HER2 is 1+ (60.4%), Ki-67 is positive (84 .4 %), positive angioinvasion (63.5 %), Invasive Ductal Carcinoma (90.6 %), high neutrophil levels (77.1 %). Conclusion: High levels of neutrophils tend to result in severe Tumor Infiltrating Lymphocytes (TILs) which will increase tumor growth, occurrence of metastases, increased positive angioinvasion, negative Estrogen Receptor status, negative Progesterone Receptor status, HER2 1+ status, positive Ki-67 status.
Warm Autoimmune Hemolytic Anemia with Chronic Hepatitis B Wahyudi, Adefri; Fadrian; Afriant, Rudy
Sumatera Medical Journal Vol. 7 No. 1 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i1.11836

Abstract

Background: Warm autoimmune hemolytic anemia (wAIHA) is caused by erithrocytes destruction by IgG or IgG plus C3d-mediated autoantibody. Objective: To present a case of warm autoimmune hemolytic anemia (wAIHA) in a patient with chronic hepatitis B infection. Methods: This is a case report that showed a special case. Results: Man, 64 y.o, hospitalized with diagnosis wAIHA and chronic hepatitis B. Diagnosis of wAIHA is built by: severe normocytic normochromic anemia, reticulocytosis 42.29%, increasing lactate dehydrogenase 397 U/L, direct Coombs test (+4), antibody screening IgG (+4). Anothers laboratorium findings: HbsAg (+), albumin 3.5 g/dL, ALT U/L, rapid HIV (-), anti HCV (-). There is no blast found in peripheral blood and bone marrow smear. Patient also diagnosed chronic hepatitis B inactive phase with negative HbeAg, HBV DNA 547 IU/L, normal liver finding in abdominal USG and moderate fibrosis from fibroscan. Washed red cell transfussion was administered, 2 x 125 mg methilprednisolone iv (3 days) tapering off until to 40 mg/day doses. He did not get antiviral prophylaxis and be planned to reevaluate in next 6 months. Conclusion: Steroid is first line therapy in wAIHA. When wAIHA is diagnosed, determination of chronic hepatitis B status should confirmed.  There is a risk of reactivation of chronic hepatitis B infection so monitoring is needed.
Diabetic Ketoacidosis in Type 1 Diabetes Mellitus Nurhakim, Lukman; Afriant, Rudy; Aprilia, Dinda
Sumatera Medical Journal Vol. 7 No. 1 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i1.11837

Abstract

Background: Diabetic ketoacidosis (DKA) is a state of metabolic decompensation/disorder characterized by the triad of hyperglycemia, acidosis and ketosis, caused by absolute or relative insulin deficiency and increased counter-regulatory hormones. Objective: To report a case of diabetic ketoacidosis (DKA) in a young adult patient with type 1 diabetes mellitus and scalp abscess, emphasizing the importance of early diagnosis and prompt management to achieve clinical improvement. Methods: This case report describes the clinical presentation, diagnostic approach, and therapeutic management of a 19-year-old male with DKA. Results: A 19-year-old male treated in the internal medicine ward of Dr. M djamil Padang with diabetic ketoacidosis, type 1 DM, and Abscess capitis. The patient was treated with rehydration and intravenous insulin infusion can show clinical improvement. Conclusion: The diagnosis in patients is based on anamnesis, physical examination and supporting examinations. Immediate therapy is needed in the management of DKA in patients. After DKA is resolved, look for the causes of the risk of DKA. On the third day of treatment the patient's condition improved clinically and the laboratory.
Cerebral Toxoplasmosis and Latent Tuberculosis Infection in HIV Infected Patient Arridho, Rijalun; Raveinal; Dwitya Elvira
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.11843

Abstract

Background: Toxoplasmosis is an opportunistic infection caused by Toxopasma gondii, which affects one third of the global human population and commonly involves the central nervous system (CNS)/brain. The diagnosis of obvious sign of imaging method cerebral toxoplasmosis is commonly reported in several case report, but subclinical sign of imaging is uncommon reported. Objective: we reported a case of 28-years-old male with chief complaint headache that worsening since 3 days before admission. Methods: This is a case report. Results: He was first recognized as HIV infected patient on hospital admission. CT scan revealed minimal perifocal oedema in left frontal region. Patient was diagnosed as cerebral toxoplasmosis and latent tuberculosis infection in HIV clinical stadium IV. Patient recieved empirical therapy of cerebral toxoplasmosis and symptom relieved after 7 days of treatment. Cerebral toxoplasmosisis typically associated with HIV infected patient that result in the reactivation of Toxoplasma gondii infection. Conclusions: Clinical presentation of CNS toxoplasmosis varies and normal brain CT can be found despited presumptive diagnosis was revealed.
Level of Knowledge, Attitude, and Behavior of Students at SMA Negeri 13 Medan on Prevention of Sexually Transmitted Infections Elisabeth; Magdalena Simatupang, Maria; Munir, Delfitri; Rasiyanti Siregar, Olga
Sumatera Medical Journal Vol. 7 No. 1 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i1.12045

Abstract

Background: Sexually Transmitted Infection (STI) is a contagious disease that has been a health problem around people all over the world because the incidence rate of sexually transmitted diseases (STDs) tends to increase. Objective: This research objects to know the level of knowledge, attitudes and behavior of SMA Negeri 13 Medan students regarding STI prevention. Methods: This is descriptive research with cross-sectional design. The sampling technique is done by stratified random sampling with questionnaire as data collection tool and the data analysis was carried out using descriptive statistics. Results: The results showed that the knowledge level of SMA Negeri 13 Medan students about preventing STI was mostly in the good category (54.2%), attitudes were in the good category (93.7%), and behaviors were in the moderate category (47.9%). Conclusion: Most of students have a good knowledge level, good attitude level, and moderate behavior level towards STI prevention.
The Diagnostic Challenge of Distinguishing Temporal Lobe Encephaloceles from Sphenoid Sinus Mucoceles Chin, Ein Wan; Goh , Liang Chye; Chong, Aun Wee
Sumatera Medical Journal Vol. 7 No. 1 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i1.14299

Abstract

Background: Temporal lobe encephaloceles are rare defects involving brain herniation through the skull base, often misdiagnosed as sphenoid sinus mucoceles—cystic lesions due to mucus buildup. Both conditions share overlapping neurological, nasal, and ophthalmologic symptoms, but require different treatments. Objective: To emphasize the importance of accurate diagnosis in distinguishing temporal lobe encephaloceles from sphenoid sinus mucoceles and to highlight the role of imaging in clinical management. Methods: A 27-year-old healthy man presented with seizure and loss of consciousness, with a history of head trauma 13 years earlier. Physical examinations, including cranial nerve and cerebellar assessments, were normal. Rigid nasoendoscopy was unremarkable. Imaging included CT and brain MRI. Results: CT scan suggested an expanded left sphenoid sinus likely mucocele with temporal lobe encephalomalacia. Brain MRI confirmed a left temporal lobe encephalocele. The patient underwent successful transcranial repair. Conclusion: Misinterpretation of imaging may lead to incorrect management. Comprehensive evaluation, particularly with MRI, is essential to differentiate encephaloceles from mucoceles for appropriate treatment planning.
Herbal Therapies in Cancer Patients: Managing Side Effects and Improving Quality of Life Anand, Keshav; Kaur Massaon, Harpreet; Prabhakar , P. K.
Sumatera Medical Journal Vol. 7 No. 1 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i1.14603

Abstract

Background: As conventional cancer treatments often induce a myriad of adverse effects, ranging from nausea and fatigue to pain and emotional distress, the integration of herbal therapies has gained attention as a potential complementary approach. Objective: The review synthesizes existing literature, drawing upon both preclinical and clinical studies, to evaluate the efficacy and safety of various herbs in alleviating common side effects associated with cancer therapies. Methods: This review article employs a narrative review approach, systematically collecting and analyzing findings from preclinical and clinical studies. Results: Special emphasis is placed on the potential benefits of herbal interventions in addressing physical symptoms, such as nausea and pain, as well as psychological and emotional challenges faced by cancer patients. Furthermore, the review explores the mechanisms of action behind these herbal interventions and potential synergies with conventional treatments. Conclusion: By providing a critical analysis of the current state of knowledge, this review aims to guide healthcare professionals, researchers, and patients in making informed decisions regarding the integration of herbal therapies into cancer care, ultimately improving the supportive care and quality of life for individuals undergoing cancer treatment.
A Study on Impact of Covid-19 on the Nutrition and Exercise Regime of Lifestyle Disorder Patients (Non-Communicable Disease) Mahendher, Sheetal; Paul, Shantanu; Sharma, Anshitha; L, Leonard
Sumatera Medical Journal Vol. 7 No. 1 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i1.14616

Abstract

Background: The COVID-19 pandemic has significantly altered people's eating and activity habits all around the world. Lockdowns and social isolation policies have altered daily routines, changed people's levels of physical activity, and changed how they eat. Objective: The goal of this study is to fill in the knowledge gaps regarding the effects of COVID-19 on people who have lifestyle disorders by studying the variations in exercise routines and the necessary nutrition intake during and after the lockdown. Methods: In order to gather information from people with NCDs, the study used a mixed-methods approach that combines a questionnaire survey and focused discussion. Results: The study offers insights into how people with lifestyle disorders alter their exercise regimens, exercise style, and adherence to nutritional diets. The findings show that the pandemic has driven people to change their workout routines, moving away from gyms and outside activities toward alternate at-home techniques. Conclusion: The study also emphasizes the difficulties people encountered in sticking to rigorous nutritional diets during the epidemic because of the restricted availability of fresh and nourishing foods. It further highlights the significance of consistent exercise and mindful eating for those with lifestyle disorders, particularly during times of crisis.
A Study on Impact of Covid-19 on Job Performance & Job Satisfaction of Employees Engaged in WFH Culture Mahendher, Sheetal; Pattanayak, Siddharth
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.14646

Abstract

Background: Coronavirus (COVID-19), which hit in early 2020, altered people's lives and livelihoods. Objective: The goal of this study was to fill in the gaps by looking into numerous possible determinants of job satisfaction and employee performance while working from home, such as work–life balance and work stress, as well as the influence of COVID-19. Methods: This study is descriptive design, a cross sectional study, the data is collected using primary methods that is widely accepted to measure the job satisfaction and employee performance during working from home. Results: Age of respondent was100% of the respondents belong to the category of the age group 18-30. Gender of the respondents -68.2% of the respondents were male while 31.8 % of the respondents belong to the female category. Occupation of the respondents - 86.4% of the respondents were students while 13.6% belong to the employed category. As the significance value that is .072 so it depicts that Covid-19 has a statistically 0.72 impact on Employee performance. Conclusion: Working from home might be a positive indicator in reaction to the collectivist environment.
Protein Programmed Death-Ligand 1 Expression in Non-Small Cell Lung Cancer (NSCLC) and Its Correlation to Smoking Status in North Sumatera Population Soeroso, Noni Novisari; Tarigan, Setia Putra; Rahmat Hidayat; Elisna Syahruddin; Evlin Suzanna; Dian Chayadi
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.15289

Abstract

Background: Tobacco smoking is associated to the increase risk of lung cancer, and smoking could also trigger the tumour proportion score from programmed death ligand (PD-L1). Objective: This study aims to identify the correlation of non-small cell lung cancer (NSCLC) with the PD-L1 expression and smoking profile on the North Sumatra Population. Methods: This research implemented a descriptive study with cross-sectional design. Results: This study was carried out from August 2019 to September 2020. Results: Characteristics of patients with NSCLC to the PD-L1 expression were found more in male patients with percentage of 88.6%, whereas the most common type of cancer is adenocarcinoma, accounting for 97.14% of cases with mild degree smoking index for 45.7% (Brinkman index) and IV-stage of clinical status for 68.6%. The tumour proportion score with 1-49% was 51.4% with high expression of PD-L1 (positive) for 74.28%, while lower expression of PD-L1 accounted for 45%. Conclusion: There is a correlation between PD-L1 expression and smoking status in NSCLC patients, with p-value of 0.037 (<0.05).

Page 13 of 17 | Total Record : 169

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