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Dina Keumala Sari
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Jl. Dr. T. Mansur No. 9 Padang Bulan, Kecamatan Medan Baru, Kota medan, Sumatera Utara, Indonesia
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Sumatera Medical Journal
Published by Universitas Sumatera Utara
ISSN : 26229234     EISSN : 26221357     DOI : 10.32734
Core Subject : Health, Science,
Immunology & microbiology Medicine & Pharmacology
Sumatera Medical Journal (SUMEJ) provides a forum for publishing the full research articles in the area of Medical Science related to topics from the following subject areas: -Cancer and Related Aspects -Biomoleculer in Basic Sciences -Biomoleculer in Clinical Sciences -Tissue Engineering including Stem Cell -Medical and Health Sciences
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 169 Documents
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A Natural Food Colourant from Dioscorea alata (Dandila) in Sri Lanka: Development, Storage Stability and Bio-active Properties Menike, W.A.E.M.P.; Sajiwanie, J.W.A.; Rathnayaka, R.M.U.S.K.
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.15784

Abstract

Background: Though anthocyanins are popular as natural food colourants with additional functional properties, their instability limited their utilization in the industry. Objective: this study aimed to formulate a natural food colourant by the microwave-assisted encapsulation of Dandila (Dioscorea alata) anthocyanins to enhance the storage stability of the pigments in ambient conditions and to study the storage stability and the bio-active properties of the formulated colourant. Methods: This was an in vitro study, the steps were acidified water was used as the solvent to extract the anthocyanins from Dandila yams. The colourant formulation encapsulated with maltodextrin (30 mg/ml) was selected as the best encapsulation treatment for Dandila anthocyanin. Anthocyanin degradation was not significant during the tested 12 months of storage period. Results: Noteworthy values were obtained for Total Phenolic Content and anti-oxidant activity. Among the tested strains in the antimicrobial assay, the natural colourant showed inhibitory activities against Escherichia coli and Streptococcus pneumoniae. Conclusions:  confirm the successful development of a natural colourant rich in bio-active properties from Dandila anthocyanin while ensuring its storage stability in ambient conditions.
Glucose to Complications: Understanding Secondary Effects in Diabetes Mellitus P. K. Prabhakar
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.15998

Abstract

Background: Diabetes Mellitus (DM) is a complex metabolic disorder characterized by persistent hyperglycemia, impacting millions globally. While glucose control is central to its management, understanding secondary complications is crucial for comprehensive care. Objective: This paper explores the intricate relationship "From Glucose to Complications" in DM, elucidating the pathophysiological mechanisms and organ system involvement. Methods: This paper emphasizes preventive strategies and holistic management approaches to mitigate complications. Results: Microvascular complications encompass diabetic retinopathy, nephropathy, and neuropathy, each posing significant morbidity and mortality risks. Macrovascular complications, including atherosclerosis and stroke, contribute substantially to cardiovascular morbidity in diabetic individuals. Metabolic derangements such as dyslipidemia and obesity further exacerbate the risk profile. Endocrine disturbances, neurological sequelae, and cognitive impairments represent additional burdens in DM management. Conclusion: effective management of Diabetes Mellitus (DM) and its associated complications necessitates a multifaceted approach encompassing glycemic control, lifestyle interventions, and pharmacological therapies.
Unraveling the Complexities of Polycystic Ovarian Syndrome: A Comprehensive Review Archana Kumari; Satya Narayan jha
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.16035

Abstract

Background: Polycystic Ovarian Syndrome (PCOS) is a complex endocrine disorder affecting reproductive-age women, characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology. Objective: The aimed was to explore the key topics including the role of insulin resistance and hyperinsulinemia in PCOS pathogenesis, the impact of hormonal imbalances on menstrual irregularities and fertility, and the association of PCOS with metabolic syndrome and cardiovascular risk factors. Methods: This comprehensive review delves into the multifaceted nature of PCOS, exploring its etiology, pathophysiology, clinical manifestations, diagnostic criteria, and management strategies. Results: The review discusses current diagnostic criteria and controversies surrounding PCOS diagnosis, as well as evidence-based approaches to treatment, encompassing lifestyle modifications, pharmacological interventions, and assisted reproductive technologies. Conclusion: By synthesizing current knowledge and emerging research findings, this review aims to provide a comprehensive overview of PCOS for clinicians, researchers, and individuals affected by this prevalent endocrine disorder.
Depression and Type 2 Diabetes: Dissecting the Causal Mechanisms Awani Kumar Diwakar
Sumatera Medical Journal Vol. 7 No. 2 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i2.16112

Abstract

Background: Depression and Type 2 Diabetes (T2D) are two prevalent and debilitating chronic conditions that often coexist and exhibit a bidirectional relationship. Objective: This aims was to dissect the causal mechanisms underlying the association between depression and T2D, shedding light on the complex interplay between these two disorders. Methods: This was review paper that will explore about epidemiological evidence that found association between depression and an increased risk of developing T2D, as well as a reciprocal relationship where T2D serves as a risk factor for depression onset. Results: Various biological, psychological, and behavioral mechanisms have been proposed to underlie this bidirectional relationship. Depression is thought to contribute to the development of T2D through dysregulation of neuroendocrine pathways, increased inflammation, alterations in lifestyle behaviors, and poor treatment adherence. Conversely, T2D may exacerbate or precipitate depression through mechanisms involving insulin resistance, hyperglycemia-induced neuronal damage, inflammation, and the impact of chronic illness on psychological well-being. Conclusion: Understanding the causal mechanisms underlying the depression-T2D relationship is crucial for informing clinical practice, public health strategies, and the development of personalized interventions aimed at mitigating the burden of these interconnected disorders.
Parasite Contamination of Water Source at Pangkalan Masyhur Sub-district, Medan Johor District Hutagalung, Sunna Vyatra; Khairuna Damanik, Rahmah; Rattaprasert, Pongruj
Sumatera Medical Journal Vol. 7 No. 3 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i3.11826

Abstract

Background: Water utilization by humans and animals can generate biological pollutants which may contaminate the water. These contaminants come from waste products that may contain bacteria, protozoa, and other parasites. Objective:  The aims of this study was to determine the contamination of water source by pathogens, particularly parasites at Medan, North Sumatera, Indonesia. Methods: This was a descriptive study with cross sectional design and simple random sampling. Results: We found Paramecium caudatum from nine samples (8,7%) collected from the open wells and the nearby river streams, followed by hookworm larva in one tap water sample (1%). Conclusion: No protozoa such as Entamoeba spp., Cryptosporidium spp., and Giardia spp. found in any of the samples. Based on this data, the abundant presence of P.caudatum represented the condition of high organic debris in the open wells and the nearby river streams. Additionally, the presence of hookworm larva in the tap water indicated the distribution system was contaminated with the surrounding soil.
Amoebic Liver Abscess Multifocal With Bilateral Parapneumonic Effusion: A Case Report Hartanto, Bayu Arief; Arnelis; Fauzar; Wahyudi
Sumatera Medical Journal Vol. 7 No. 3 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i3.11844

Abstract

Background: A liver abscess is defined as a pus-filled mass in the liver that can develop from injury to the liver or an intraabdominal infection disseminated from the portal circulation. Objective: The aim was to discuss about liver abscesses are categorized into pyogenic or amoebic caused by Entamoeba histolytica. Methods: This is a case report that reported about pus-filled mass in the liver. Results: A male patient, 53 years old, was admitted to Hospital for Upper right abdominal pain, Fever, Cough, Pain in the lower right chest. Chest examination found weakened bronchovesicular breath sounds as high as RIC V, Pleural Friction Rub, wet crackles. Abdominal Examination found supel palpation, liver palpable 2 fingers below the arcus costae and 2 fingers below the process xiphoid, blunt edge, soft consistency, tenderness pain in the dextra hypochondrium. Laboratory report Anti Amoeba : Positive 40,3 unit. The patient was given intravenous metronidazole therapy 3x750 mg for 10 days. Conclusion: Complications of amoebic liver abscess is pleuropulmonary involvement. Pulmonary and pleural amebiasis is an uncommon disease, usually occurring on the right side of the lung compared to the left side.
Frequency Distribution of Oncology Patients Who Come to Emergency Department at H. Adam Malik Hospital, Medan Basri Siregar, Kamal; Manik, David Restu; Hakim, Luqmanul; Gultom, Habib Solihin; Naqib bin Md Ghazali, Muhammad
Sumatera Medical Journal Vol. 7 No. 3 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i3.13698

Abstract

Background: A multidisciplinary approach is needed to comprehensively evaluate cancer patient’s condition and understanding patient demographic characteristics can improve health care by adapting to each patient's needs. Objective: The aim of this study was to explore about frequency distribution of oncolohy patients. Methods: This research is a descriptive observational study with a cross-sectional study design conducted at the Haji Adam Malik General Hospital in Medan on oncology patients who met the inclusion criteria. Data with a numerical measuring scale will be presented in mean+standard deviation (SD) and data with a categorical measuring scale will be presented in frequencies and percentages. Results: The results showed that majority of patients were in 46–59 year age group as much as 32 patients (37.2%) and 58 patients (67.4%) were female. The highest level of education was found in 26 patients (30.2%) as bachelor, and 45 patients (52.3%) lived in Medan City. Most patients came to be treated at the surgical installation as many as 50 patients (25.6%). Conclusion: The research results found that majority of patients are in the age group 46-59 years, female, bachelor, domicile in Medan and are treated in surgical installation.
Associations Between Knowledge, Attitude and Behavior With Helminthiasis in Children Alyssa, Agnesia; Saputri, Dewi
Sumatera Medical Journal Vol. 7 No. 3 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i3.13770

Abstract

Background: Soil-transmitted helminths (STH) infection is currently one of the highest prevalence neglected tropical diseases in children. Factors contributing to such case are children’s hygiene, as well as the existence of helminths in the surrounding soil. Objective: Therefore, this research is done to determine whether there is significant association between hygiene and STH infection in children. Methods: This observational analysis with a cross-sectional design was conducted on elementary school children by interviewing the children and obtaining fecal samples. Results: Analysis of 197 fecal samples shows that 14.7% of the children were infected with STH and results of the interview show more children had poor knowledge about STH infection (69%). Good hygiene attitude and behavior were found in the majority of the subjects (58.9% and 81.7% respectively). The chi-square analysis performed shows no significant relation between knowledge (p=0.626), attitude (p=0.975), and behavior (p=0.376) and the incidence of STH infection. Conclusion: In this study, although children demonstrated poor knowledge of STH infection but had good hygiene attitudes and behaviors, there was no significant link between these factors and STH infection. This emphasizes the need for ongoing hygiene education in elementary school children.
Lipid Profile in Type 2 Diabetes Mellitus Patients With and Without Diabetic Retinopathy Agustian, Fadhlan Hatta; Wardany, Yulia
Sumatera Medical Journal Vol. 7 No. 3 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i3.15462

Abstract

Background: Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia due to abnormalities in insulin secretion, insulin action, or both. Objective: To analyze differences in the proportion of lipid profile categories in type 2 DM patients with and without diabetic retinopathy. Methods: This was a hospital-based cross-sectional study with 45 samples. The independent variables assessed were the lipid profile, including LDL, HDL, triglycerides, and total cholesterol levels. The dependent variable assessed was the incidence of diabetic retinopathy. The analysis used were univariate and bivariate (Chi-square and Fisher exact). Results: The prevalence of diabetic retinopathy was 37.8%, consist of 17.8% of NPDR and 20% of PDR. There were significant differences in the proportion of LDL categories (p=0.007) and total cholesterol (p=0.038) in type 2 DM patients with and without diabetic retinopathy, and there were no significant differences in the proportion of HDL categories (p=0.719) and triglycerides (p=1) in type 2 DM patients with and without diabetic retinopathy. Conclusion: There were significant differences in the proportion of LDL categories and total cholesterol in type 2 DM patients with and without diabetic retinopathy.
Parents Education is One of Affected Factor in Stunted Children Profile in Pekanbaru Wardhana, Nabillah Nastiti; Zahtamal
Sumatera Medical Journal Vol. 7 No. 3 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i3.15513

Abstract

Background: Stunting is a developmental disorder in children caused by poor nutrition, recurrent infections, and inadequate psychosocial stimulation, marked by the child's height or length being below the threshold (Z-Score) of -2 standard deviations. Objective: The aim of this study was to explore prevalence of stunting in Pekanbaru. Methods: This was descriptive research with quantitative data, and the sample size was 75. Results: The family profile of those with stunted children included fathers with mostly secondary education (64%), mothers with secondary education (57.3%), 19 mothers experiencing short stature (CED), with only four mothers receiving additional food, mothers who took iron supplements during pregnancy (80%), children with stunting who were exclusively breastfed (78.7%) and introduced to complementary feeding (80%), children with stunting taken to integrated health posts for regular growth and development monitoring (76%), children with stunting receiving complete immunization (57.3%), families participating in family planning programs (60%), and children with stunting resulting from unwanted pregnancies (40%). Conclusion: The majority of parents with stunted children had a lower to middle education level, low income, did not participate in the national health insurance program (JKN), and did not receive either cash or food assistance.

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