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<![CDATA[WASPADA EPIDEMI HIV-AIDS DI INDONESIA ]]>
<![CDATA[., Handayani]]>
<![CDATA[ Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY ]]>
Publisher : <![CDATA[UNUSA Press ]]>
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DOI: 10.33086/mhsj.v1i1.610
<![CDATA[One of the major health problem in Indonesia is the spreading of Acuquired Immune Deficiency Sidrome(AIDS) and Human Immuno Deficiency Virus(HIV). The development of HIV-AIDS in Indonesia is veryalarming. The high number of people living with HIV-AIDS will affect on demography structure, health caresystems, national economic and social order. Combating HIV-AIDS face a variety of complex challenges,requiring both a policy and action at the national, regional, and global. How to coverage prevention andtreatment of HIV-AIDS, strengthening the quality of health services, assurance of drug availability,appropriate and effective regulation, elimination of stigma and discrimination, as well as tests and treatmentsfor patients. Indonesian government have to involve various parties in HIV-AIDS, especially from the fieldof socio-cultural, educational, and religious for the prevention and improvement of patient care need tochange people's behavior.]]>
<![CDATA[OVERVIEW CHARACTERISTICS AND P2Y12 REACTIVITY UNIT (PRU) VALUES OF ACUTE CORONARY SYNDROME AGE PRODUCTIVE PATIENTS WITH CLOPIDOGREL THERAPY ]]>
<![CDATA[., Rahmatini]]>;
<![CDATA[Aliska, Gestina]]>;
<![CDATA[Syafri, Masrul]]>
<![CDATA[ Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY ]]>
Publisher : <![CDATA[UNUSA Press ]]>
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DOI: 10.33086/mhsj.v1i1.612
<![CDATA[ABSTRACTBackground: Ischemic heart disease is the leading cause of death and disability in the world with a fairlyhigh portion coming from countries Low- and Middle-Income (LMICs). In Pakistan, 54% patients acutecoronary syndrome (ACS) was resistant to clopidogrel, and no data on clopidogrel resistance on ethnicMinang. This study aims to look at the characteristics and P2Y12 Reactivity Unit (PRU) from ACS patientsin Dr. M. Djamil Hospital, Padang. Methods: This research is a cross sectional study. The effectiveness ofclopidogrel on platelet reactivity identified through examination of PRU value using VerifyNow® with a cutoff point is 208. From the PRU values, it can be classified whether patients resistant or responsive. The studywas conducted in September 2016. Result: From 14 patients with ACS who received clopidogrel, 11 patients(78.57%) are male with 3 female patients (21.43). The mean of age was 53.78 years old. Patients mostlycame from West Sumatra provinces (92,85%) and 7,15% from others. From all of patients head risk factorsof coronary arterial disease. Hipertension was the greatest risk factor. Conclusion: It can be concluded thatmost of the patients were male. From PRU data, 7 patients (50%) were resistant and 7 patients (50%) wereresponse to clopidogrel. Further research is needed with larger numbers of patients and investigatepharmacogenetic profile of CYP2C19 as caused of resistance.]]>
<![CDATA[PENGARUH PEMBERIAN VITAMIN C, VITAMIN E, DAN KROMIUM (CR3+) TERHADAP KADAR INSULIN TIKUS WISTAR YANG DIINDUKSI ALOKSAN ]]>
<![CDATA[Mutiarani, Anugrah Linda]]>
<![CDATA[ Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY ]]>
Publisher : <![CDATA[UNUSA Press ]]>
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DOI: 10.33086/mhsj.v1i1.613
<![CDATA[Objective: To analyze the effect of vitamin C, vitamin E, and chromium (Cr3+) on insulin levels Wistar ratswere induced alloxan.Materials and Methods: This study is an experimental laboratory. Using rats typeWistar strain Rattus novergicus for 6 weeks with a number of 20 head. The independent variables consist of 5treatment groups namely normal diet, normal diet + 1 g/hr chromium, normal diet + 2 mg/day of vitamin C,normal diet + 0.5 mg/day of vitamin E, normal diet + 1 g/hr chromium + 2 mg/day of vitamin C + 0.5mg/day of vitamin E. The dependent variable is the level of insulin. To know the differences of eachtreatment used statistical tests One Way ANOVA, followed by Tukey HSD Post Hoc test withp<0.05.Results: There were significant differences in insulin levels (p<0.05) in the control group, 1, 2, and 4.But in the control group and the group 3 there are no significant differences in insulin levels (p=0.145).Conclusion: Delivery of chromium (treatment 1), vitamin C (treatment 2), and a mixture of chromium,vitamin C, vitamin E (treatment 4) effect on insulin levels, while administration of vitamin E (treatment 3)alone had no effect on insulin levels]]>
<![CDATA[POTENSI MODIFIKASI MODEL PIERS UNTUK PREDIKSI LUARAN IBU DENGAN PREEKLAMSIA PADA RUMAH SAKIT TIPE B DI INDONESIA: PENELITIAN RETROSPEKTIF DI RSUD ANSARI SALEH BANJARMASIN, KALIMANTAN SELATAN ]]>
<![CDATA[Sufriyana, Herdiantri]]>;
<![CDATA[Handayani, Lisda]]>;
<![CDATA[Yuliana, Fitri]]>;
<![CDATA[Syafi'i, Taufiq]]>
<![CDATA[ Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY ]]>
Publisher : <![CDATA[UNUSA Press ]]>
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DOI: 10.33086/mhsj.v1i1.614
<![CDATA[ABSTRACTBackground: Preeclampsia is the most common cause (32%) of maternal deaths in Indonesia. Model Piers(Pre-eclampsia Integrated Estimate Risk) can predict the outcomes / complications of pre-eclampsia andassociated with a reduction in maternal morbidity. This study aims to assess the potential modification of themodel to predict the outcome Piers mothers with preeclampsia in Type B hospitals in Indonesia. Methods:This research is a prognostic with the analytical method and quantitative approach retrospectively. This studyused the capture technique stratified random sampling to obtain the medical records of 160 people withpreeclampsia and 160 controls in hospitals Banjarmasin Ansari Saleh 2014. Identified availability ofvariables in the model along with the outer piers preeclampsia. Performed univariate, bivariate andmultivariate corresponding availability of variables the model Piers. Result: eight of the 48 variables in themodel Piers consistently found in all samples, while output available were complication preeclampsiaeclampsia and/or HELLP syndrome. The gestational age was significantly influent eclampsia for the subjectin this study (P <0.05), HELLP syndrome (P <0.05), and a combination of both (P <0.01). Predictive value ofa logistic regression model with the variables that the outer form of the syndrome HELLP or in combinationwith eclampsia is 0.811 (AUC ROC; CI 95% from 0.636 to 0.986) and 0.767 (AUC ROC; CI 95% 0.666 to0.868), while the prediction of eclampsia was not significant (P> 0.05). Conclusion: Modifications Piersmodels to predict potential outcomes of women with preeclampsia in RS type B in Indonesia if it is supportedby policies and standards that consider this model and supported a larger number of samples.]]>
<![CDATA[JUMLAH RELATIF SEL NEUTROFIL (GR-1+) PADA MENCIT (MUS MUSCULUS) TERINFEKSI STAPHYLOCOCCUS AUREUS SETELAH PEMBERIAN EKSTRAK BUAH MENGKUDU (MORINDA CITRIFOLIA L.) ]]>
<![CDATA[Mufidah, Zumrotul]]>
<![CDATA[ Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY ]]>
Publisher : <![CDATA[UNUSA Press ]]>
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DOI: 10.33086/mhsj.v1i1.615
<![CDATA[Objective: The aim of this study was to determine the relative number of neutrophil (GR-1+) on miceinfected Staphylococcus aureus after treatment noni (Morinda citrifolia L.) crude extract. Methods: Micewere devided into two group: non-infected and infected. Non infected group was without S.aureus infectionwhereas the infected group was infected with S.aureus. Group contain kontrol, dose 1 (25 mg/kg BW), dose 2(100 mg/kg BW), and dose 3 (300 mg/kg BW). Oral treatment carried out for 20 days in every morning andeach sample was injected with S.aureus at day 21 with 109 cell/mL. Relative number of neutrophil (GR-1+)was measured using the BD FACSCaliburTM Flowcytometer. Data were analyzed by using Analysis ofVarians (p<0,05) and SPSS 16 for windows. Result: The result showed that administration of noni crudeextract was significantly change the relative number of neutrophil (GR-1+). Conclusion: Treatment of noni(M. citrifolia) crude extract could increase relative amount of neutrophil (GR-1+) on infected S.aureus andwithout infected group. That might be caused by active compound on noni crude extract that can influenceactivity of increasing Granulocyte Colony Stimulating Factor (G-CSF) so can increase relative amount ofneutrophil (GR-1+).]]>
<![CDATA[TINGKAT PENGETAHUAN KESEHATAN REPRODUKSI PADA SISWA SMA KANJENG SEPUH GRESIK ]]>
<![CDATA[Afridah, Wiwik]]>;
<![CDATA[Fajariana, Ratna]]>
<![CDATA[ Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY ]]>
Publisher : <![CDATA[UNUSA Press ]]>
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DOI: 10.33086/mhsj.v1i1.616
<![CDATA[ABSTRACTBackground: Adolescence is a transitional period between the time of children with adulthood. There are stillmany found little regard for teens on health on reproductive, will consequently risk against the occurrence ofan increase in diseases, among others; Sexually Transmitted Infections (STI). Methods: This type of researchis the pre-design experiments using One-Shot Case Study, measured through a questionnaire. Class X studentpopulation of 33 students, XI IPS 2 of 26 students, and XII IPS 1 of 29 students. With a variable level ofknowledge about reproductive health education, sexually transmitted diseases, prevention and theintroduction of infectious disease symptoms, processed and analyzed using descriptive statistics. Results: Theresults of the research on reproductive health education on class X most (63, 64%) have moderate levels ofknowledge about sexually transmitted diseases in class XI IPS 2 most (73%), 8 have a level of knowledge,level of knowledge about the prevention of infectious diseases and the introduction at the XII 1st most IPS(58, 62%) have moderate levels of knowledge. Conclusion: the level of knowledge of students of SMKKanjeng Sepuh Gresik about adolescent reproductive health is on a category of being. Therefore the expectedreproductive and Sexual health education as a subject/local content through the media of the school as aproper step as a medium of education can provide information on sexual and reproductive health is right forteens.]]>
<![CDATA[PENGARUH SUPLEMENTASI VITAMIN D TERHADAP NILAI PENGUKURAN FEV1/ FVC PADA PENDERITA ASMA TERKONTROL SEBAGIAN ]]>
<![CDATA[Donastin, Adyan]]>;
<![CDATA[Bakhtiar, Arief]]>;
<![CDATA[Maranatha, Daniel]]>
<![CDATA[ Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY ]]>
Publisher : <![CDATA[UNUSA Press ]]>
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DOI: 10.33086/mhsj.v1i1.617
<![CDATA[Background:Airflow resistance in asthma caused by changes in the airways that is bronchoconstriction,airway edema, airway hyperresponsiveness and airway remodeling. Vitamin D supplementation is expectedto raise the value of the measurement of FEV1/ FVC in patients with asthma controlled in part through therole of vitamin D in terms of antiviral effects, atopic response, response improvement steroid and preventairway remodeling process.Objective:Comparing the measurement values of FEV1/ FVC in patients withasthma controlled most of which do not get supplemental vitamin D than getting supplemental vitaminD.Methods:This study is a randomized experimental simple study. This research was conducted in drSoetomo Hospital from June to July 2015. The sampling technique using consecutive sampling. Sampleswere divided into two groups each consisting of 14 samples which have earned a combined therapy ofinhaled corticosteroids and LABA. The control group that was not given additional vitamin Dsupplementation and the treatment group were given supplements of vitamin D for 1 month. Measurementand main result:Testing of data distribution using the ShapiroWilk method because the sample size is lessthan 50. The result of the difference in FEV1 / FVC with a paired sample t - test is known that in the controlgroup (not given additional vitamin D supplements) did not occur significant difference (p = 0.219> 0.05),while the treatment group (given additional vitamin supplements D) proved significant difference (p = 0.020<0.05) where the value of FEV1 / FVC after being given additional vitamin D supplements increased to96.071% of the initial conditions is 84.786%.Conclusions:The measurement values of FEV1/ FVC in patientswith asthma controlled most of which get vitamin D supplementation are the most significant increasecompared to the control group who did not receive supplementation ofvitamin D.]]>
<![CDATA[PENGARUH PEMBERIAN TOPIKAL EKSTRAK KOLAGEN KULIT IKAN LELE SANGKURIANG (CLARIAS GARIEPINUS VAR) TERHADAP TNF-Α DAN JUMLAH FIBROBLAST PADA LUKA BAKAR DERAJAT DUA TIKUS WISTAR ]]>
<![CDATA[., Aisyah]]>;
<![CDATA[Mufarikoh, Zainatul]]>;
<![CDATA[Andini, Ary]]>
<![CDATA[ Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY ]]>
Publisher : <![CDATA[UNUSA Press ]]>
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DOI: 10.33086/mhsj.v1i1.611
<![CDATA[ABSTRACTBackground: Collagen has vital role on healing process of burn injuries, mainly in connective tissue.Collagen triggers fibroblast proliferation, support to form new granulation tissue and epithelium aroundwound. Wound treatment through collagen extract of Sangkuriang catfish skin can increase healing process.It stimulates humidity on level II burn injuries and encourage re-epithelization, proliferation and cellmigration also increases growth. Methods: This is an experimental studies using 4 groups of RattusNorvegicus (Wistar strain). All of the group get a burn injuries in their back skin. Control group 1 (K1) wastreated by lidocaine for three days and control group 2 (K2) for ten days. Whereas treatment group 1 (P1) getlidocaine and collagen extract from Sangkuriang cat fish for 3 days and treatment group 2 (P2) for 10 days.Result: Number of fibroblast/field of view on treatment group showed significantly increased comparedcontrol groups on the 3rd days (P=0,046) and the 10th (P=0,004). Percentage of TNF-? on level II-burninjuries in wistar rats showed significant difference. Percentage of TNF-? lower than treatment group andshowed significant lowering level compared control groups on the10th (P=0,022). Conclusion: Increasing offiroblast number and lowering level of TNF-? significantly showed collagen extract of Sangkuriang cat fishskin accelerate wound healing process.]]>
<![CDATA[WASPADA EPIDEMI HIV-AIDS DI INDONESIA ]]>
<![CDATA[Handayani .]]>
<![CDATA[ Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY ]]>
Publisher : <![CDATA[UNUSA Press ]]>
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DOI: 10.33086/mhsj.v1i1.610
<![CDATA[One of the major health problem in Indonesia is the spreading of Acuquired Immune Deficiency Sidrome(AIDS) and Human Immuno Deficiency Virus(HIV). The development of HIV-AIDS in Indonesia is veryalarming. The high number of people living with HIV-AIDS will affect on demography structure, health caresystems, national economic and social order. Combating HIV-AIDS face a variety of complex challenges,requiring both a policy and action at the national, regional, and global. How to coverage prevention andtreatment of HIV-AIDS, strengthening the quality of health services, assurance of drug availability,appropriate and effective regulation, elimination of stigma and discrimination, as well as tests and treatmentsfor patients. Indonesian government have to involve various parties in HIV-AIDS, especially from the fieldof socio-cultural, educational, and religious for the prevention and improvement of patient care need tochange people's behavior.]]>
<![CDATA[PENGARUH PEMBERIAN TOPIKAL EKSTRAK KOLAGEN KULIT IKAN LELE SANGKURIANG (CLARIAS GARIEPINUS VAR) TERHADAP TNF-Α DAN JUMLAH FIBROBLAST PADA LUKA BAKAR DERAJAT DUA TIKUS WISTAR ]]>
<![CDATA[Aisyah .]]>;
<![CDATA[Zainatul Mufarikoh]]>;
<![CDATA[Ary Andini]]>
<![CDATA[ Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY ]]>
Publisher : <![CDATA[UNUSA Press ]]>
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DOI: 10.33086/mhsj.v1i1.611
<![CDATA[ABSTRACTBackground: Collagen has vital role on healing process of burn injuries, mainly in connective tissue.Collagen triggers fibroblast proliferation, support to form new granulation tissue and epithelium aroundwound. Wound treatment through collagen extract of Sangkuriang catfish skin can increase healing process.It stimulates humidity on level II burn injuries and encourage re-epithelization, proliferation and cellmigration also increases growth. Methods: This is an experimental studies using 4 groups of RattusNorvegicus (Wistar strain). All of the group get a burn injuries in their back skin. Control group 1 (K1) wastreated by lidocaine for three days and control group 2 (K2) for ten days. Whereas treatment group 1 (P1) getlidocaine and collagen extract from Sangkuriang cat fish for 3 days and treatment group 2 (P2) for 10 days.Result: Number of fibroblast/field of view on treatment group showed significantly increased comparedcontrol groups on the 3rd days (P=0,046) and the 10th (P=0,004). Percentage of TNF-α on level II-burninjuries in wistar rats showed significant difference. Percentage of TNF-α lower than treatment group andshowed significant lowering level compared control groups on the10th (P=0,022). Conclusion: Increasing offiroblast number and lowering level of TNF-α significantly showed collagen extract of Sangkuriang cat fishskin accelerate wound healing process.]]>
