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Medical and Health Science Journal
Published by Universitas Nahdlatul Ulama Surabaya
ISSN : 25497588     EISSN : 25497596     DOI : https://doi.org/10.33086/mhsj
Core Subject : Health, Social,
Health Professions Social Sciences
Medical and Health Science (MHSJ) published peer-reviewed original articles research, case report or article review. This journal is published twice (February and August) by Faculty of Medicine Universitas Nahdlatul Ulama Surabaya.
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Articles 190 Documents
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SKRINING HIV PADA REMAJA DI SURABAYA DENGAN MENGGUNAKAN RAPID TEST S, Thomas; A, Rahayu; ., Handayani; Alamudi, M. Yusuf
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 2 (2017): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i2.608

Abstract

Abstrak: HIV (Human Immunodeficiency Virus) merupakan retrovirus bersifat limfotropik khasyang menginfeksi sel-sel dari sistem kekebalan tubuh, menghancurkan atau merusak sel darah putihspesifik yang disebut limfosit T-helper atau limfosit pembawa faktor T4 (CD4). Virus ini diklasifikasikan dalam famili Retroviridae, subfamili Lentiviridae, genus Lentivirus. Jumlah kematianHIV/AIDS di kalangan remaja di seluruh dunia yang meningkat sebesar 50 persen antara tahun2005 dan 2012 menunjukkan tren mengkhawatirkan. Laporan badan PBB yang menangani masalahanak-anak UNICEF menyebutkan sekitar 71.000 remaja berusia antara 10 dan 19 tahun meninggaldunia karena virus HIV pada tahun 2005. Jumlah itu meningkat menjadi 110.000 jiwa pada tahun2012. Unit Perawatan Intermediet dan Penyakit Infeksi (UPIPI) RSUD dr. Soetomo Surabaya. 1.780pasien yang rutin berobat di UPIPI, sedangkan jumlah pengunjung setiap bulannya mencapai 2.000orang, yakni 50 di antaranya adalah pasien anak-anak dan sisanya dewasa. Kebanyakan pasienberumur antara 20 hingga 30 tahun dari berbagai wilayah yang tersebar di Jatim, seperti Surabaya,Sidoarjo, Gresik, Jember, maupun Pasuruan. Tujuan dari penelitian ini mendeteksi virus HIV padaremaja di Surabaya dengan menggunakan rapid test. Sebanyak 54 orang remaja di Surabaya diambildarahnya, dipisahkan dan dicek dengan menggunakan rapid test. Prosedur mengikuti manual rapidtest. Hasil penelitian menunjukkan bahwa dari 54 sampel dengan menggunakan rapid testmenunjukkan hasil negatif terhadap HIV.
WASPADA EPIDEMI HIV-AIDS DI INDONESIA ., Handayani
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.610

Abstract

One of the major health problem in Indonesia is the spreading of Acuquired Immune Deficiency Sidrome(AIDS) and Human Immuno Deficiency Virus(HIV). The development of HIV-AIDS in Indonesia is veryalarming. The high number of people living with HIV-AIDS will affect on demography structure, health caresystems, national economic and social order. Combating HIV-AIDS face a variety of complex challenges,requiring both a policy and action at the national, regional, and global. How to coverage prevention andtreatment of HIV-AIDS, strengthening the quality of health services, assurance of drug availability,appropriate and effective regulation, elimination of stigma and discrimination, as well as tests and treatmentsfor patients. Indonesian government have to involve various parties in HIV-AIDS, especially from the fieldof socio-cultural, educational, and religious for the prevention and improvement of patient care need tochange people's behavior.
OVERVIEW CHARACTERISTICS AND P2Y12 REACTIVITY UNIT (PRU) VALUES OF ACUTE CORONARY SYNDROME AGE PRODUCTIVE PATIENTS WITH CLOPIDOGREL THERAPY ., Rahmatini; Aliska, Gestina; Syafri, Masrul
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.612

Abstract

ABSTRACTBackground: Ischemic heart disease is the leading cause of death and disability in the world with a fairlyhigh portion coming from countries Low- and Middle-Income (LMICs). In Pakistan, 54% patients acutecoronary syndrome (ACS) was resistant to clopidogrel, and no data on clopidogrel resistance on ethnicMinang. This study aims to look at the characteristics and P2Y12 Reactivity Unit (PRU) from ACS patientsin Dr. M. Djamil Hospital, Padang. Methods: This research is a cross sectional study. The effectiveness ofclopidogrel on platelet reactivity identified through examination of PRU value using VerifyNow® with a cutoff point is 208. From the PRU values, it can be classified whether patients resistant or responsive. The studywas conducted in September 2016. Result: From 14 patients with ACS who received clopidogrel, 11 patients(78.57%) are male with 3 female patients (21.43). The mean of age was 53.78 years old. Patients mostlycame from West Sumatra provinces (92,85%) and 7,15% from others. From all of patients head risk factorsof coronary arterial disease. Hipertension was the greatest risk factor. Conclusion: It can be concluded thatmost of the patients were male. From PRU data, 7 patients (50%) were resistant and 7 patients (50%) wereresponse to clopidogrel. Further research is needed with larger numbers of patients and investigatepharmacogenetic profile of CYP2C19 as caused of resistance.
PENGARUH PEMBERIAN VITAMIN C, VITAMIN E, DAN KROMIUM (CR3+) TERHADAP KADAR INSULIN TIKUS WISTAR YANG DIINDUKSI ALOKSAN Mutiarani, Anugrah Linda
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.613

Abstract

Objective: To analyze the effect of vitamin C, vitamin E, and chromium (Cr3+) on insulin levels Wistar ratswere induced alloxan.Materials and Methods: This study is an experimental laboratory. Using rats typeWistar strain Rattus novergicus for 6 weeks with a number of 20 head. The independent variables consist of 5treatment groups namely normal diet, normal diet + 1 g/hr chromium, normal diet + 2 mg/day of vitamin C,normal diet + 0.5 mg/day of vitamin E, normal diet + 1 g/hr chromium + 2 mg/day of vitamin C + 0.5mg/day of vitamin E. The dependent variable is the level of insulin. To know the differences of eachtreatment used statistical tests One Way ANOVA, followed by Tukey HSD Post Hoc test withp<0.05.Results: There were significant differences in insulin levels (p<0.05) in the control group, 1, 2, and 4.But in the control group and the group 3 there are no significant differences in insulin levels (p=0.145).Conclusion: Delivery of chromium (treatment 1), vitamin C (treatment 2), and a mixture of chromium,vitamin C, vitamin E (treatment 4) effect on insulin levels, while administration of vitamin E (treatment 3)alone had no effect on insulin levels
POTENSI MODIFIKASI MODEL PIERS UNTUK PREDIKSI LUARAN IBU DENGAN PREEKLAMSIA PADA RUMAH SAKIT TIPE B DI INDONESIA: PENELITIAN RETROSPEKTIF DI RSUD ANSARI SALEH BANJARMASIN, KALIMANTAN SELATAN Sufriyana, Herdiantri; Handayani, Lisda; Yuliana, Fitri; Syafi'i, Taufiq
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.614

Abstract

ABSTRACTBackground: Preeclampsia is the most common cause (32%) of maternal deaths in Indonesia. Model Piers(Pre-eclampsia Integrated Estimate Risk) can predict the outcomes / complications of pre-eclampsia andassociated with a reduction in maternal morbidity. This study aims to assess the potential modification of themodel to predict the outcome Piers mothers with preeclampsia in Type B hospitals in Indonesia. Methods:This research is a prognostic with the analytical method and quantitative approach retrospectively. This studyused the capture technique stratified random sampling to obtain the medical records of 160 people withpreeclampsia and 160 controls in hospitals Banjarmasin Ansari Saleh 2014. Identified availability ofvariables in the model along with the outer piers preeclampsia. Performed univariate, bivariate andmultivariate corresponding availability of variables the model Piers. Result: eight of the 48 variables in themodel Piers consistently found in all samples, while output available were complication preeclampsiaeclampsia and/or HELLP syndrome. The gestational age was significantly influent eclampsia for the subjectin this study (P <0.05), HELLP syndrome (P <0.05), and a combination of both (P <0.01). Predictive value ofa logistic regression model with the variables that the outer form of the syndrome HELLP or in combinationwith eclampsia is 0.811 (AUC ROC; CI 95% from 0.636 to 0.986) and 0.767 (AUC ROC; CI 95% 0.666 to0.868), while the prediction of eclampsia was not significant (P> 0.05). Conclusion: Modifications Piersmodels to predict potential outcomes of women with preeclampsia in RS type B in Indonesia if it is supportedby policies and standards that consider this model and supported a larger number of samples.
JUMLAH RELATIF SEL NEUTROFIL (GR-1+) PADA MENCIT (MUS MUSCULUS) TERINFEKSI STAPHYLOCOCCUS AUREUS SETELAH PEMBERIAN EKSTRAK BUAH MENGKUDU (MORINDA CITRIFOLIA L.) Mufidah, Zumrotul
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.615

Abstract

Objective: The aim of this study was to determine the relative number of neutrophil (GR-1+) on miceinfected Staphylococcus aureus after treatment noni (Morinda citrifolia L.) crude extract. Methods: Micewere devided into two group: non-infected and infected. Non infected group was without S.aureus infectionwhereas the infected group was infected with S.aureus. Group contain kontrol, dose 1 (25 mg/kg BW), dose 2(100 mg/kg BW), and dose 3 (300 mg/kg BW). Oral treatment carried out for 20 days in every morning andeach sample was injected with S.aureus at day 21 with 109 cell/mL. Relative number of neutrophil (GR-1+)was measured using the BD FACSCaliburTM Flowcytometer. Data were analyzed by using Analysis ofVarians (p<0,05) and SPSS 16 for windows. Result: The result showed that administration of noni crudeextract was significantly change the relative number of neutrophil (GR-1+). Conclusion: Treatment of noni(M. citrifolia) crude extract could increase relative amount of neutrophil (GR-1+) on infected S.aureus andwithout infected group. That might be caused by active compound on noni crude extract that can influenceactivity of increasing Granulocyte Colony Stimulating Factor (G-CSF) so can increase relative amount ofneutrophil (GR-1+).
TINGKAT PENGETAHUAN KESEHATAN REPRODUKSI PADA SISWA SMA KANJENG SEPUH GRESIK Afridah, Wiwik; Fajariana, Ratna
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.616

Abstract

ABSTRACTBackground: Adolescence is a transitional period between the time of children with adulthood. There are stillmany found little regard for teens on health on reproductive, will consequently risk against the occurrence ofan increase in diseases, among others; Sexually Transmitted Infections (STI). Methods: This type of researchis the pre-design experiments using One-Shot Case Study, measured through a questionnaire. Class X studentpopulation of 33 students, XI IPS 2 of 26 students, and XII IPS 1 of 29 students. With a variable level ofknowledge about reproductive health education, sexually transmitted diseases, prevention and theintroduction of infectious disease symptoms, processed and analyzed using descriptive statistics. Results: Theresults of the research on reproductive health education on class X most (63, 64%) have moderate levels ofknowledge about sexually transmitted diseases in class XI IPS 2 most (73%), 8 have a level of knowledge,level of knowledge about the prevention of infectious diseases and the introduction at the XII 1st most IPS(58, 62%) have moderate levels of knowledge. Conclusion: the level of knowledge of students of SMKKanjeng Sepuh Gresik about adolescent reproductive health is on a category of being. Therefore the expectedreproductive and Sexual health education as a subject/local content through the media of the school as aproper step as a medium of education can provide information on sexual and reproductive health is right forteens.
PENGARUH SUPLEMENTASI VITAMIN D TERHADAP NILAI PENGUKURAN FEV1/ FVC PADA PENDERITA ASMA TERKONTROL SEBAGIAN Donastin, Adyan; Bakhtiar, Arief; Maranatha, Daniel
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.617

Abstract

Background:Airflow resistance in asthma caused by changes in the airways that is bronchoconstriction,airway edema, airway hyperresponsiveness and airway remodeling. Vitamin D supplementation is expectedto raise the value of the measurement of FEV1/ FVC in patients with asthma controlled in part through therole of vitamin D in terms of antiviral effects, atopic response, response improvement steroid and preventairway remodeling process.Objective:Comparing the measurement values of FEV1/ FVC in patients withasthma controlled most of which do not get supplemental vitamin D than getting supplemental vitaminD.Methods:This study is a randomized experimental simple study. This research was conducted in drSoetomo Hospital from June to July 2015. The sampling technique using consecutive sampling. Sampleswere divided into two groups each consisting of 14 samples which have earned a combined therapy ofinhaled corticosteroids and LABA. The control group that was not given additional vitamin Dsupplementation and the treatment group were given supplements of vitamin D for 1 month. Measurementand main result:Testing of data distribution using the ShapiroWilk method because the sample size is lessthan 50. The result of the difference in FEV1 / FVC with a paired sample t - test is known that in the controlgroup (not given additional vitamin D supplements) did not occur significant difference (p = 0.219> 0.05),while the treatment group (given additional vitamin supplements D) proved significant difference (p = 0.020<0.05) where the value of FEV1 / FVC after being given additional vitamin D supplements increased to96.071% of the initial conditions is 84.786%.Conclusions:The measurement values of FEV1/ FVC in patientswith asthma controlled most of which get vitamin D supplementation are the most significant increasecompared to the control group who did not receive supplementation ofvitamin D.
PENGARUH EKSTRAK BUAH MENGKUDU (MORINDA CITRIFOLIA) TERHADAP KADAR KOLESTEROL TOTAL DARAH PADA TIKUS PUTIH (RATTUS NORVEGICUS) JANTANGALUR WISTARYANG DIBERI DIET TINGGI LEMAK Priadna, Astrid Ika; Adiwinoto, Budiarto; Handajani, Fitri
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 1 (2019): February
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: High cholesterol dietinduced hypercholesterolemia. Noni fruit extracthas flavonoids which are expected to reduceblood total cholesterol levels.This study aims to determine the effect of noni fruit extract (Morinda citrifolia) on total blood cholesterol levels in wistar strain male rats (Rattus norvegicus) given a high-fat diet. Method: Experimental study using post test only control group design. A total of 24 wistar strain male rats were divided into 3 groups: negative controlgroup given standard feed; positive control group of experimental animals who were given a high-fat diet; the experimental group treated with a high-fat diet for 14 days and given noni fruit extractat a dose of 200 mg / Kg BB. On the 29th day total blood cholesterol levels were measured for all groups of experimental animals. Results: The Mann Whitney UTest showed a significant increase in total blood cholesterol levels in the positive group of experimental animals given a high-fat diet (68.13 mg/dl) compared to the negative control group of experimental animals given standard feed (51.25 mg/dl). There was a significant decrease in total blood cholesterol levels in the experimental group treated with a high-fat diet and noni fruit extract (61mg/dl) compared to the average positive control group of experimental animals given a high-fat diet (68.13 mg/dl). Conclusion: Provision of a high-fat diet in wistar strain male ratscan significantly increase total blood cholesterol levels. The administration of noni fruit extract in wistar strain male ratscan significantly reduce total blood cholesterol levels
PENINGKATAN PENGETAHUAN GURU TENTANG P3K MELALUI PROMOSI KESEHATAN DI SMK KAL 1 SURABAYA Rinarto, Nisha Dharmayanti; Priyantini, Dwi; Fitriastuti, Annisa Nurayu
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 1 (2019): February
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Health promotion is an effort planned to influence other people, whether individuals, groups or communities, so that they do what is expected by health promotion actors. Health promotion of P3K in schools has an effect on the level of knowledge that teachers have about P3K on emergencies. This study aims to see the effect of health promotion on increasing teacher knowledge about first aid at Surabaya KAL-1 Vocational School. Sampling technique with Simple Random Sampling, a total sample of 39 respondents. The research method is Pre Experimental with the One Group Pretest-Posttest approach. Data collection using questionnaires. Data analysis techniques using the Wilcoxon Signed Rank Test. The results of the study showed that the teacher's knowledge before being given a health promotion with an average value of 1.38 and after being given a health promotion obtained an average value of 2.54. The results of statistical tests obtained the results of Asymp. Sig 0.001> α 0.05, which means that there are significant differences. Further analysis found that there was an effect of health promotion on the level of teacher knowledge, so it was hoped that the school would propose to the relevant UPTD for the provision of first aid training in schools

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