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Medical and Health Science Journal
Published by Universitas Nahdlatul Ulama Surabaya
ISSN : 25497588     EISSN : 25497596     DOI : https://doi.org/10.33086/mhsj
Core Subject : Health, Social,
Health Professions Social Sciences
Medical and Health Science (MHSJ) published peer-reviewed original articles research, case report or article review. This journal is published twice (February and August) by Faculty of Medicine Universitas Nahdlatul Ulama Surabaya.
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Articles 192 Documents
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HUBUNGAN ANTARA KADAR TROPONIN DENGAN KEJADIAN MAJOR ADVERSE CARDIOVASCULAR EVENTS PADA PASIEN SINDROM KORONER AKUT DI RSI JEMURSARI SURABAYA Elsa Kusumawati; Abraham Ahmad Ali Firdaus; Reza Hery Mahendra Putra
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 1 (2018): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i1.607

Abstract

Abstrak: Sindroma Koroner Akut (SKA) memiliki variabilitas yang cukup besar dalam risiko outcome dan mortalitas. Major Adverse Cardiovascular Events (MACE) adalah hasil akhir SKA yangdidefinisikan sebagai aritmia, syok kardiogenik, gagal jantung, dan kematian. Troponin adalah protein spesifik yang berasal dari otot jantung, di mana fungsinya adalah regulasi kontraksi otot jantung.Kejadian MACE sering ditemukan pada pasien SKA meskipun pasien telah menjalani perawatanintensif. Dengan demikian, dibutuhkan prediksi awal yang besar untuk mengetahui risiko MACEpada penderita SKA, dalam hal ini berupa troponin. Penelitian ini bertujuan untuk mengetahuikadar troponin yang meningkat, sehingga dapat lebih berhati-hati mencegah kejadian MACE padapasien SKA. Cross-sectional pada pasien SKA yang dirawat di RSI Jemursari Surabaya pada bulanJanuari 2014–Desember 2016. Pengambilan sampel dengan teknik consecutive sampling, sebanyak68 orang. Data dianalisis dengan uji chi-square. Penderita laki-laki lebih banyak dibandingkan denganpenderita perempuan. Kelompok usia terbanyak yang menderita SKA adalah 56-65 tahun, denganrentang usia 35-85 dan rerata usia 59, 45±11,447 tahun. Hasil penelitian ini menunjukkan bahwaterdapat korelasi antara peningkatan troponin dengan kejadian Major Adverse Cardiovascular Events(MACE) pada pasien sindrom koroner akut dan nilai signifikansi p<0,002. Hasil Odss Ratio (OR)pada pasien SKA dengan peningkatan troponin sebesar 6,5 (IK 95% 2,112-20,282) p<0,002. Adakorelasi antara peningkatan kadar troponin dengan kejadian Major Adverse Cardiovascular Events(MACE) pada pasien dengan sindrom koroner akut.
SKRINING HIV PADA REMAJA DI SURABAYA DENGAN MENGGUNAKAN RAPID TEST Thomas S; Rahayu A; Handayani .; M. Yusuf Alamudi
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 2 (2017): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i2.608

Abstract

Abstrak: HIV (Human Immunodeficiency Virus) merupakan retrovirus bersifat limfotropik khasyang menginfeksi sel-sel dari sistem kekebalan tubuh, menghancurkan atau merusak sel darah putihspesifik yang disebut limfosit T-helper atau limfosit pembawa faktor T4 (CD4). Virus ini diklasifikasikan dalam famili Retroviridae, subfamili Lentiviridae, genus Lentivirus. Jumlah kematianHIV/AIDS di kalangan remaja di seluruh dunia yang meningkat sebesar 50 persen antara tahun2005 dan 2012 menunjukkan tren mengkhawatirkan. Laporan badan PBB yang menangani masalahanak-anak UNICEF menyebutkan sekitar 71.000 remaja berusia antara 10 dan 19 tahun meninggaldunia karena virus HIV pada tahun 2005. Jumlah itu meningkat menjadi 110.000 jiwa pada tahun2012. Unit Perawatan Intermediet dan Penyakit Infeksi (UPIPI) RSUD dr. Soetomo Surabaya. 1.780pasien yang rutin berobat di UPIPI, sedangkan jumlah pengunjung setiap bulannya mencapai 2.000orang, yakni 50 di antaranya adalah pasien anak-anak dan sisanya dewasa. Kebanyakan pasienberumur antara 20 hingga 30 tahun dari berbagai wilayah yang tersebar di Jatim, seperti Surabaya,Sidoarjo, Gresik, Jember, maupun Pasuruan. Tujuan dari penelitian ini mendeteksi virus HIV padaremaja di Surabaya dengan menggunakan rapid test. Sebanyak 54 orang remaja di Surabaya diambildarahnya, dipisahkan dan dicek dengan menggunakan rapid test. Prosedur mengikuti manual rapidtest. Hasil penelitian menunjukkan bahwa dari 54 sampel dengan menggunakan rapid testmenunjukkan hasil negatif terhadap HIV.
GAMBARAN STATUS GIZI ANAK KELAS VI DI SEKOLAH DASAR MIFTAKHUL ULUM SURABAYA Novera Herdiani; Wiwik Afridah
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 1 (2018): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i1.609

Abstract

Abstract: Background, nutritional status is a description of balance between the need of nutrientsfor keeping a good life, to maintenance normal body function also energy production in one sideand the consumption of nutrients in the other. Children in elementary school are the best target forimprovement of community nutrition because in the childhood the function of the brain organbegan to form so the development of intelligence is quite rapid. Lack of nutritional intake inchildren can inhibit the physical growth and thinking ability in children and subsequently reduce inlearning interest. Therefore the nutritional status of the children must detect immediately to carryout the preventive measurements. Objective, the purpose of this study is to know the nutritionalstatus of children at grade VI in elementary school Miftakhul Ulum Surabaya based on height andweight. Methods, this study is a quantitative descriptive using survey method, weighting indexinstrument by height in children aged 6–17 years old from Health Department in 2011. This studyused the measurement of body weight and height. Subjects of this study were all students at grade VIin elementary school Miftakhul Ulum Surabaya, which amount 81 children. Data collecting techniques use anthropometric measurements which include measurement of body weight and heightthen calculated base of data analysis techniques using quantitative descriptive with percentage.Result, study results showed most of the students were 12 years old (56.80%), mostly male (55.60%).most of them have body height 130–140 cm (37.00%), and body weight 31–40 kg (46,90%). Malechildren have more problems with their nutritional status (51.10%). Male children much oftenhave underweight and over weight (13.30%) than girls. By the increasing their age, their BMI willbe normal category (100%). By the age of 13 and 14 years old, the children will not have underweight (0%). Conclusion, based on the nutritional status of all children at grade VI, it can beconcluded that the nutritional status of children at grade VI in elementary school Miftakhul UlumSurabaya is in underweight category (very thin and lean) with percentage 56.80%. While the normal weight percentage 32.10%, and over weight (fat and obesity) with percentage 11.10%.
WASPADA EPIDEMI HIV-AIDS DI INDONESIA Handayani .
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.610

Abstract

One of the major health problem in Indonesia is the spreading of Acuquired Immune Deficiency Sidrome(AIDS) and Human Immuno Deficiency Virus(HIV). The development of HIV-AIDS in Indonesia is veryalarming. The high number of people living with HIV-AIDS will affect on demography structure, health caresystems, national economic and social order. Combating HIV-AIDS face a variety of complex challenges,requiring both a policy and action at the national, regional, and global. How to coverage prevention andtreatment of HIV-AIDS, strengthening the quality of health services, assurance of drug availability,appropriate and effective regulation, elimination of stigma and discrimination, as well as tests and treatmentsfor patients. Indonesian government have to involve various parties in HIV-AIDS, especially from the fieldof socio-cultural, educational, and religious for the prevention and improvement of patient care need tochange people's behavior.
PENGARUH PEMBERIAN TOPIKAL EKSTRAK KOLAGEN KULIT IKAN LELE SANGKURIANG (CLARIAS GARIEPINUS VAR) TERHADAP TNF-Α DAN JUMLAH FIBROBLAST PADA LUKA BAKAR DERAJAT DUA TIKUS WISTAR Aisyah .; Zainatul Mufarikoh; Ary Andini
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.611

Abstract

ABSTRACTBackground: Collagen has vital role on healing process of burn injuries, mainly in connective tissue.Collagen triggers fibroblast proliferation, support to form new granulation tissue and epithelium aroundwound. Wound treatment through collagen extract of Sangkuriang catfish skin can increase healing process.It stimulates humidity on level II burn injuries and encourage re-epithelization, proliferation and cellmigration also increases growth. Methods: This is an experimental studies using 4 groups of RattusNorvegicus (Wistar strain). All of the group get a burn injuries in their back skin. Control group 1 (K1) wastreated by lidocaine for three days and control group 2 (K2) for ten days. Whereas treatment group 1 (P1) getlidocaine and collagen extract from Sangkuriang cat fish for 3 days and treatment group 2 (P2) for 10 days.Result: Number of fibroblast/field of view on treatment group showed significantly increased comparedcontrol groups on the 3rd days (P=0,046) and the 10th (P=0,004). Percentage of TNF-α on level II-burninjuries in wistar rats showed significant difference. Percentage of TNF-α lower than treatment group andshowed significant lowering level compared control groups on the10th (P=0,022). Conclusion: Increasing offiroblast number and lowering level of TNF-α significantly showed collagen extract of Sangkuriang cat fishskin accelerate wound healing process.
OVERVIEW CHARACTERISTICS AND P2Y12 REACTIVITY UNIT (PRU) VALUES OF ACUTE CORONARY SYNDROME AGE PRODUCTIVE PATIENTS WITH CLOPIDOGREL THERAPY Rahmatini .; Gestina Aliska; Masrul Syafri
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.612

Abstract

ABSTRACTBackground: Ischemic heart disease is the leading cause of death and disability in the world with a fairlyhigh portion coming from countries Low- and Middle-Income (LMICs). In Pakistan, 54% patients acutecoronary syndrome (ACS) was resistant to clopidogrel, and no data on clopidogrel resistance on ethnicMinang. This study aims to look at the characteristics and P2Y12 Reactivity Unit (PRU) from ACS patientsin Dr. M. Djamil Hospital, Padang. Methods: This research is a cross sectional study. The effectiveness ofclopidogrel on platelet reactivity identified through examination of PRU value using VerifyNow® with a cutoff point is 208. From the PRU values, it can be classified whether patients resistant or responsive. The studywas conducted in September 2016. Result: From 14 patients with ACS who received clopidogrel, 11 patients(78.57%) are male with 3 female patients (21.43). The mean of age was 53.78 years old. Patients mostlycame from West Sumatra provinces (92,85%) and 7,15% from others. From all of patients head risk factorsof coronary arterial disease. Hipertension was the greatest risk factor. Conclusion: It can be concluded thatmost of the patients were male. From PRU data, 7 patients (50%) were resistant and 7 patients (50%) wereresponse to clopidogrel. Further research is needed with larger numbers of patients and investigatepharmacogenetic profile of CYP2C19 as caused of resistance.
PENGARUH PEMBERIAN VITAMIN C, VITAMIN E, DAN KROMIUM (CR3+) TERHADAP KADAR INSULIN TIKUS WISTAR YANG DIINDUKSI ALOKSAN Anugrah Linda Mutiarani
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.613

Abstract

Objective: To analyze the effect of vitamin C, vitamin E, and chromium (Cr3+) on insulin levels Wistar ratswere induced alloxan.Materials and Methods: This study is an experimental laboratory. Using rats typeWistar strain Rattus novergicus for 6 weeks with a number of 20 head. The independent variables consist of 5treatment groups namely normal diet, normal diet + 1 g/hr chromium, normal diet + 2 mg/day of vitamin C,normal diet + 0.5 mg/day of vitamin E, normal diet + 1 g/hr chromium + 2 mg/day of vitamin C + 0.5mg/day of vitamin E. The dependent variable is the level of insulin. To know the differences of eachtreatment used statistical tests One Way ANOVA, followed by Tukey HSD Post Hoc test withp<0.05.Results: There were significant differences in insulin levels (p<0.05) in the control group, 1, 2, and 4.But in the control group and the group 3 there are no significant differences in insulin levels (p=0.145).Conclusion: Delivery of chromium (treatment 1), vitamin C (treatment 2), and a mixture of chromium,vitamin C, vitamin E (treatment 4) effect on insulin levels, while administration of vitamin E (treatment 3)alone had no effect on insulin levels
POTENSI MODIFIKASI MODEL PIERS UNTUK PREDIKSI LUARAN IBU DENGAN PREEKLAMSIA PADA RUMAH SAKIT TIPE B DI INDONESIA: PENELITIAN RETROSPEKTIF DI RSUD ANSARI SALEH BANJARMASIN, KALIMANTAN SELATAN Herdiantri Sufriyana; Lisda Handayani; Fitri Yuliana; Taufiq Syafi'i
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.614

Abstract

ABSTRACTBackground: Preeclampsia is the most common cause (32%) of maternal deaths in Indonesia. Model Piers(Pre-eclampsia Integrated Estimate Risk) can predict the outcomes / complications of pre-eclampsia andassociated with a reduction in maternal morbidity. This study aims to assess the potential modification of themodel to predict the outcome Piers mothers with preeclampsia in Type B hospitals in Indonesia. Methods:This research is a prognostic with the analytical method and quantitative approach retrospectively. This studyused the capture technique stratified random sampling to obtain the medical records of 160 people withpreeclampsia and 160 controls in hospitals Banjarmasin Ansari Saleh 2014. Identified availability ofvariables in the model along with the outer piers preeclampsia. Performed univariate, bivariate andmultivariate corresponding availability of variables the model Piers. Result: eight of the 48 variables in themodel Piers consistently found in all samples, while output available were complication preeclampsiaeclampsia and/or HELLP syndrome. The gestational age was significantly influent eclampsia for the subjectin this study (P <0.05), HELLP syndrome (P <0.05), and a combination of both (P <0.01). Predictive value ofa logistic regression model with the variables that the outer form of the syndrome HELLP or in combinationwith eclampsia is 0.811 (AUC ROC; CI 95% from 0.636 to 0.986) and 0.767 (AUC ROC; CI 95% 0.666 to0.868), while the prediction of eclampsia was not significant (P> 0.05). Conclusion: Modifications Piersmodels to predict potential outcomes of women with preeclampsia in RS type B in Indonesia if it is supportedby policies and standards that consider this model and supported a larger number of samples.
JUMLAH RELATIF SEL NEUTROFIL (GR-1+) PADA MENCIT (MUS MUSCULUS) TERINFEKSI STAPHYLOCOCCUS AUREUS SETELAH PEMBERIAN EKSTRAK BUAH MENGKUDU (MORINDA CITRIFOLIA L.) Zumrotul Mufidah
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.615

Abstract

Objective: The aim of this study was to determine the relative number of neutrophil (GR-1+) on miceinfected Staphylococcus aureus after treatment noni (Morinda citrifolia L.) crude extract. Methods: Micewere devided into two group: non-infected and infected. Non infected group was without S.aureus infectionwhereas the infected group was infected with S.aureus. Group contain kontrol, dose 1 (25 mg/kg BW), dose 2(100 mg/kg BW), and dose 3 (300 mg/kg BW). Oral treatment carried out for 20 days in every morning andeach sample was injected with S.aureus at day 21 with 109 cell/mL. Relative number of neutrophil (GR-1+)was measured using the BD FACSCaliburTM Flowcytometer. Data were analyzed by using Analysis ofVarians (p<0,05) and SPSS 16 for windows. Result: The result showed that administration of noni crudeextract was significantly change the relative number of neutrophil (GR-1+). Conclusion: Treatment of noni(M. citrifolia) crude extract could increase relative amount of neutrophil (GR-1+) on infected S.aureus andwithout infected group. That might be caused by active compound on noni crude extract that can influenceactivity of increasing Granulocyte Colony Stimulating Factor (G-CSF) so can increase relative amount ofneutrophil (GR-1+).
TINGKAT PENGETAHUAN KESEHATAN REPRODUKSI PADA SISWA SMA KANJENG SEPUH GRESIK Wiwik Afridah; Ratna Fajariana
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.616

Abstract

ABSTRACTBackground: Adolescence is a transitional period between the time of children with adulthood. There are stillmany found little regard for teens on health on reproductive, will consequently risk against the occurrence ofan increase in diseases, among others; Sexually Transmitted Infections (STI). Methods: This type of researchis the pre-design experiments using One-Shot Case Study, measured through a questionnaire. Class X studentpopulation of 33 students, XI IPS 2 of 26 students, and XII IPS 1 of 29 students. With a variable level ofknowledge about reproductive health education, sexually transmitted diseases, prevention and theintroduction of infectious disease symptoms, processed and analyzed using descriptive statistics. Results: Theresults of the research on reproductive health education on class X most (63, 64%) have moderate levels ofknowledge about sexually transmitted diseases in class XI IPS 2 most (73%), 8 have a level of knowledge,level of knowledge about the prevention of infectious diseases and the introduction at the XII 1st most IPS(58, 62%) have moderate levels of knowledge. Conclusion: the level of knowledge of students of SMKKanjeng Sepuh Gresik about adolescent reproductive health is on a category of being. Therefore the expectedreproductive and Sexual health education as a subject/local content through the media of the school as aproper step as a medium of education can provide information on sexual and reproductive health is right forteens.

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