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Veterinary Biomedical and Clinical Journal
Published by Universitas Brawijaya
ISSN : -     EISSN : 26221012     DOI : -
Core Subject : Health, Science, Education,
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Veterinary
Veterinary Clinical and Biomedical Journal (VBCJ) is periodically peer reviewed journal that publish every January and July per year since 2019. VBCJ accommodate any articles in the field of veterinary medicine, biomedical, as well as veterinary case report.
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Articles 5 Documents
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Search results for , issue "Vol. 3 No. 2 (2021)" : 5 Documents clear
The Analysis of Pancreatic Duodenal Homeobox 1 (PDX-1) Gene Mutation Based on Blood Glucose Level on Domestic Cats (Felis catus) Post Ovaryohisterectomy Putri, Hana Mitsuki; Aulani'am, Aulani'am; Nurmaningdyah, Ajeng Aeka; Prasetyo, Dodik; Permata, Fajar Shodiq
Veterinary Biomedical and Clinical Journal Vol. 3 No. 2 (2021)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2021.003.02.5

Abstract

Ovariohysterectomy (OH) in domestic cats causes several side effects, including obesity. Obesity is closely related to diabetes. The glucoregulatory gene that will cause insulin resistance if there is a gene mutation is the PDX-1 gene. This insulin resistance will have a very immediate effect on blood glucose in the body. The study examined the relationship between PDX-1 gene polymorphisms and blood glucose levels in domestic cats with OH. The method used in this study was in vitro PCR amplification of the PDX-1 gene with Forward primers 'CCG AGC TGT CAA AGC TAG CG' and Reverse 'GAA CCG GTA GAG GGT CTT GG' and followed by sequencing of PCR products. The results showed fundamental differences in the base sequence in the PDX-1 gene sequences at c.435G>A, c.927A>T, and c.584A>G. The fundamental difference in the PDX1 gene sequence is a silent mutation
Effect of Jatropha(Jatropha curcas L.) Seeds Extract Induction on Liver Histopathology and SGPT levels (Serum Glutamic Piruvic Transaminase) on Rat (Rattus norvegicus) Fitria, Neny; Pratiwi, Herlina; Widodo, Edwin; Primajayanti, Angelia; Anggraini, Novia Dwi; Nurfitriani, Nurfitriani; Findi, Nadia
Veterinary Biomedical and Clinical Journal Vol. 3 No. 2 (2021)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2021.003.02.1

Abstract

Jatropha or Jatropha curcas L. is a plant of the Euphorbiaceae family with medicinal and non-medical uses, including oral contraceptives. The part of Jatropha that is often used is the seed. However, Jatropha seed also contains saponins, phorbol esters, currants, tannins which can cause organ poisoning. This study was conducted to determine the effect of Jatropha seed extract on liver histopathology and SGPT levels in Rattus Norvegicus rats, using a completely randomized design method. Experimental animals were divided into four groups, and each group consisted of five female rats. The groups were the control group without treatment and those treated with Jatropha seed extract orally at doses of 10, 50, and 100 mg/kg BW. The induction process was carried out every day for 14 days, on the 15th day, a necropsy was performed. Livers were taken for histological analysis, and blood samples were taken to measure SGPT levels. Results showed that the administration of Jatropha seed extract could increase SGPT levels. The administration of Jatropha seed extract at a dose of 100 mg/kg body weight induced the most severe damage of hepatocytes among the treatment groups.
Haemobartonellosis in a Domestic Cat in Indonesia: a Case Study Satriawan, Ivan; Octaviani, Devi Intan Dyah Ayu
Veterinary Biomedical and Clinical Journal Vol. 3 No. 2 (2021)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/10.21776/ub.VetBioClinJ.2021.003.02.3

Abstract

Haemobartonellosis is a disease caused by Haemobartonella felis or Mycoplasma haemofelis, which attacks red blood cells. Ctenocephalides felis could transmit Haemobartonellosis. Further, vertical transmission from mother to offspring and blood  transfusion from infected animals could transfer the disease to other animals. This report aimed to describe the diagnosis and medical treatment of haemobartonellosis in a domestic cat in Indonesia. Physical examinations and blood analysis were carried out. The cat weighed 1,4 kg with 39,3°C temperature, CRT was three seconds, mucosa looked pale, and many Ctenocephalides felis fleas were found. The clinical symptoms detected were weakness, loss of appetite, and hair loss. A blood test indicated normocytic normochromic anemia. The rod-like formation within erythrocytes in blood smear was observed. Infection with Hemobartonella felis was diagnosed based on the blood test and the presence of numerous Ctenocephalides felis. Doxycycline was administrated at 10 mg/kg BW once a day for 21 days. The cat recovered clinically after 21 days, with a good appetite, normal mucosal color, and normal temperature
The Effect of Administrated Infused Water of Red Dragon Fruit (Hylocereus polyrhizus (F.A.C. Weber) Britton & Rose) on Growth Performance of Broiler Chickens Susanto, Adi; Aditya, Nico Chandra; Damayanti, Sari'ah Cintami; Saragih, Hendry
Veterinary Biomedical and Clinical Journal Vol. 3 No. 2 (2021)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2021.003.02.4

Abstract

The use of synthetic Antibiotics Growth Promoters (AGP) in broiler rearing causes long-term negative effects. The use of red dragon fruit-infused water (IWBNM) as a natural supplement is necessary. Determine the effect of IWBNM on the growth of broiler chickens was the aim of this study. A completely randomized design using five groups with three replications was the research design used. Each replication consist of 20 chicken. IWBNM is administered through drinking water. The treatment was carried out for 21 days. The treatment consisted of P0 (Control) plain water: P (Treatment) concentration of dragon fruit. The treatment group is 1 = 0.25%; 2 = concentration 0.5% ; 3 = concentration 1% ; 4 = 2% concentration. The data was tested by One Way ANOVA, with the Least Significant Difference (LSD) test and Duncan as a follow-up test. The result showed that one ml of IWBNM contains a total flavonoid of 676,19 µg. Giving IWBNM for 21 days, in general, can improve the growth performance of broiler chickens. Measurement of morphometry and body weight on day 21 indicates the increasing growth performance of broiler chickens with the highest performance was achieved by the P4 group compared to P1, P2, P3, and P0. As for the ratio of visceral organs to body weight, IWBNM had no significant effect on both the heart and liver.
Review: Leptospirosis in Dogs in Indonesia Wiyata, Rifen Prabawan Krida Taruna; Nugroho, Widi
Veterinary Biomedical and Clinical Journal Vol. 3 No. 2 (2021)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2021.003.02.2

Abstract

Leptospirosis is an infectious disease caused by motile bacteria of the genus Leptospira. The prevalence of leptospirosis in dogs in Indonesia ranges from 13,8% - 44%, with Leptospira variants including the serovars Ichterohaemorragiae, Celledoni, Canicola, Pyrogenes, Cynopteri, Rachmati, Bataviae, Javanica, Grippotyphosa and Tarrasovi. Leptospira sp. can be transmitted through direct contact with an infected animal, soil or water contaminated with Leptospira sp. Rodents, pigs, horses, farm animals, dogs and various wild animals such as squirrels and deer can serve as carriers of Leptospira sp. Clinical symptoms of leptospirosis in dogs in Indonesia include fever, lethargy, anorexia, vomiting, jaundice, kidney disorders, dyspnea, polyuria, yellow urine, dehydration and death. The gold standard for leptospirosis testing in dogs is the MAT test, but the PCR and ELISA tests have higher sensitivity. Prevention of leptospirosis in dogs can be done by vaccination, routine disinfection of dog house and preventing dogs from direct contact with reservoir animals such as rats

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