cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Dr. dr. Puspa Wardhani, SpPK
Contact Email
admin@indonesianjournalofclinicalpathology.org
Phone
+6285733220600
Journal Mail Official
majalah.jicp@yahoo.com
Editorial Address
Laboratorium Patologi Klinik RSUD Dr. Soetomo Jl. Mayjend. Prof. Dr. Moestopo 6-8 Surabaya
Location
Kota adm. jakarta selatan,
Dki jakarta
INDONESIA
Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Published by Perhimpunan Dokter Spesialis Patologi Klinik Indonesia
ISSN : 08544263     EISSN : 24774685     DOI : https://dx.doi.org/10.24293
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience
Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) is a journal published by “Association of Clinical Pathologist” professional association. This journal displays articles in the Clinical Pathology and Medical Laboratory scope. Clinical Pathology has a couple of subdivisions, namely: Clinical Chemistry, Hematology, Immunology and Serology, Microbiology and Infectious Disease, Hepatology, Cardiovascular, Endocrinology, Blood Transfusion, Nephrology, and Molecular Biology. Scientific articles of these topics, mainly emphasize on the laboratory examinations, pathophysiology, and pathogenesis in a disease.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 10 Documents
 1 
Search results for , issue "Vol 13, No 1 (2006)" : 10 Documents clear
HITUNG KOLONI Candida Albicans DI TINJA ANAK GANGGUAN AUTISM SPECTRUM R Herawati; I Parwati; I Sjahid; C. Rita
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 13, No 1 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v13i1.879

Abstract

Candida albicans is part of the normal flora of the digestive tract, however in immunocompromised host can cause opportunisticinfection. According to Shaw’s case series study in North Carolina USA, colonization of C. albicans is increased in autism spectrumdisorders (ASD) patients. C. albicans is a dimorphism fungus, the yeast phase is grown at 37 °C and the mould phase is grown at roomtemperature. The aim of this study was to compare C. albicans colony count in stools of ASD patients and normal children, and to findcorrelation between C. albicans colony count and state of ASD. A cross sectional study was conducted from December 2004 to March 2005on 50 ASD patients and 50 normal children as controls. Diagnosis of ASD was based on the Diagnostic and Statistical Manual of MentalDisorders (DSM) IV criteria. The range of age in both groups was 2 to 6 years old. Stool specimens were collected in Sachs transportmedia. All specimens were examined in the Division of Infectious and Tropical Medicine, Department of Clinical Pathology RSHS/FKUPBandung. The specimens were examined microscopically and cultured on Sabouraud dextrose agar incubated at room temperature and37 °C. The colonies were interpreted in colony forming unit (CFU). The C. albicans was identified by colony microscopic examinationand germ tube test. The differences of C. albicans colony count between ASD and normal subject were analyzed by t-test. Correlationbetween colony count C. albicans and ASD state was analyzed using point biserial correlation. Of 50 subjects, 14 (28%) were diagnosedas pervasive developmental disorder not otherwise specified (PDD-NOS) and 36 (72%) were diagnosed as autistic disorders. There wereno significant statistical differences between ASD and normal subjects in age, sex, and nutritional status (p > 0.05). A significantcorrelation between direct microscopy and the result of Candida colony count was found (p = 0.0000). We did not find a significantdifference between the two temperature of incubations (p = 0.390). Mean of C. albicans colony count in normal subjects was 4 CFU.In contrast, the mean of C. albicans colony count in ASD subjects was 39 CFU. The mean C. albicans colony count in ASD subjects wassignificantly higher than normal subject (p = 0.012). There was a significant correlation between C. albicans colony count and the stateof ASD (Rpb0.253372; p = 0.0106) : C. albicans colony count from stool of ASD subjects was significantly higher than normal subjects.We also found a significant correlation between C. albicans colony count and the state of ASD
PROFIL LIPID PENDERITA DIABETES MELLITUS TIPE 2 P S Josten; Mutmainnah Mutmainnah; Hardjoeno Hardjoeno
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 13, No 1 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v13i1.894

Abstract

Prevalence of type 2 diabetes mellitus (DM) tends to increasing worldwide. The main cause of death in type 2 DM is coronaryheart disease (CHD) and its mortality rate can increase 2 to 4 times compared to non-diabetics. One of the risk factors in CHD isdyslipidemia. To know the lipid profile based on age and gender and to assess the relation of total cholesterol, LDL, HDL, and TG levelto age. Descriptive retrospective study in patients with type 2 DM who are 45 years old and over. From 100 Type 2 DM patients, in theDepartment of Internal Medicine, Dr. Wahidin Sudirohusodo Hospital, Makassar, period of June to December 2005, the largest age groupwith dyslipidemia was > 59 years old, with increase LDL level, 32.73% in males and 46.67% in females. There was a significant relationbetween the in crease of TG (p = 0.03) and the decrease of HDL (p = 0.02) with age. Dyslipidemia in type 2 DM patients at age group> 59 years old was shown by an increase in LDL level. The increase of TG and decrease of HDL level were significant in all age groups.Restriction of this study was not to check the antilipidemic medicine used. Early dyslipidemia of Type 2 DM should be known by lipidfraction determination and further dyslipidemia study should be conducted to predict the risk of CHD.
NILAI SMALL DENSE LDL REMAJA DAN KAITANNYA DENGAN LIPID LAINNYA Nurahami Nurahmi; S Aprianti; M. Arif; Hardjoeno Hardjoeno
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 13, No 1 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v13i1.892

Abstract

In Indonesia, coronary heart disease (CHD) as the cause of death is still the highest in number. It is estimated that the numberof deaths is about 535 per 100.000 population. Atherosclerosis represents the main risk factor which could be predicted through thepresence of small dense LDL (sdLDL) in youngsters. To determine the value of sdLDL in youngsters and its correlation with other lipids,a study was conducted cross sectionally in Makassar, from January to August 2006, on 125 youngsters aged 15 to 19 years. Their totalcholesterol, HDL, LDL, TG and ApoB was determined and sdLDL was derived from calculation of LDL/apoB ≤ 1.2. 69 (55.20%) patientsshowed sdLDL value and 56 (44.8%) patients did not show sdLDL value. Statistical calculation showed a significant correlation betweensdLDL and HDL level (p = 0.001), sdLDL and TG level (p = 0.003), and sdLDL and ApoB level (p = 0.036). Percentage of sdLDL valuewas higher in youngsters aged 15 to 19. This proves that the process of atherosclerosis happened early at a young age. Showed by theexistence of sdLDL and therefore sdLDL could be used as a predictor of atherosclerosis which can be prevented if detected earlier.
KEUNTUNGAN DAN KERUGIAN PENJAMINAN MUTU BERDASARKAN UJI MEMASTIKAN KECERMATAN (POCT) Hartono Kahar
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 13, No 1 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v13i1.898

Abstract

Laboratory examination especially for critical care such as emergency care, intensive care has been developed near the site of patientcare which is referred to point-of-care testing (POCT). As to the definition of POCT, there are many synonyms such as ancillary testing,satellite testing, and bedside testing, near patient testing, home testing, self-management, patient self-management, remote testing andphysician’s office laboratories. Based on evidence-based POCT, the National Academy of Clinical Biochemistry (NACB) has recommendedsome POCT such as coagulation tests, transcutan bilirubin testing, marker for acute coronary syndromes, diabetes mellitus, drugsand ethanol, Infectious disease testing, occult blood test, pH testing, renal function test, intraoperative PTH, renal function test andreproduction test. Some researchers conclude that performing POCT for critical care is efficient, while others found it not efficient,therefore, careful assessment of the advantages and disadvantages is important when implementing POCT. Nurses are the personnelin the acute care unit who often perform POCT; however they desire that laboratory personnel take the responsibility, therefore it isimportant to discuss which personnel are appropriate to conduct quality control of POCT.
SKLEROSIS SISTEMIK (SKLERODERMA) TERBATAS PADA SEORANG ANAK LAKI-LAKI M. Tobing; S. Darmadi; Yuliasih Yuliasih
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 13, No 1 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v13i1.896

Abstract

Systemic Sclerosis is a chronic disorder characterized by diffuse fibrosis of the skin and internal organs. The cause of systemicsclerosis is unknown, but immune responses against unknown antigens have been implicated. Symptoms usually appear in the thirdto fifth decades, and women are affected three times more frequent than men. A 13 year old boy presented with hardening of left legskin since 1 year before admittance. He was unable to both hands. The laboratory results showed slighty decreased hemoglobin, normalleucocytes and platelets, increased ESR, normal kidney and liver function tests, positive ANA test (weak), negative ENA and anti Scl-70.Other examination results showed normal X-Ray, Esophagogram, Schirmer test. Thyroid function test showed an euthyroid state. SystemicSclerosis is established based on history of illness, physical examination and laboratory tests. ESR and CRP are increased in systemicsclerosis. Anemia in scleroderma can be due to various causes such as chronic disease, iron deficiency by gastrointestinal bleeding, B12deficiency and folic acid deficiency. ANA test (IIF Hep-2) is positive in 60 –90%. Specific autoantibodies are Scl-70 and anticentromer.The anti Scl-70 can be used for prognosis.
POLA KUMAN BERDASARKAN SPESIMEN DAN SENSITIVITAS TERHADAP ANTIMIKROBA Rostina Rostina; B Rusli; M Arief; Hardjoeno Hardjoeno
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 13, No 1 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v13i1.890

Abstract

High prevalence of infectious diseases in Indonesia lead to the use of uncontrollable anti microbial treatment with less concern todrug resistance, marked with fewer requests for sensitivity testing. This leads to irrational anti microbial treatment and increasing drugresistance. With unsupported condition for using a sensitivity test prior to anti microbial treatment, a common guide for choosing ananti microbial agent for infection of specific organ system is needed. A descriptive study of retrospectively collected data of sensitivity testresults was done on 841 spesimens from sources of infected organs in Wahidin Sudirohusodo Hospital of Makassar during 2005–2006periods. Objectives of this study are to know the microbial pattern of specific organ infection (represented by microbes of the specimens),antimicrobial sensitivity pattern of the microorganisms, and whether there is shifting of the pattern within a 1 year period. Shiftingof microbial patterns during 2005–2006 period was found. Klebsiella aeroginosa, Enterobacter agglomerans, Alkaligenes faecalis andEscherichia coli were the most frequent micro organisms found from spesimens examined. Most of antimicrobial drugs commonlyused were found effective to most of micro organisms, while amikacin, cefepime, gentamycin, sulbactam, tobramycin, vancomycin andmeropene were still sensitive enough to the majority of the infectious agents.
KORELASI ANTARA PERIKSAAN DARAH SAMAR TINJA MENGGUNAKAN ANTI-HEMOGLOBIN MANUSIA DAN PENGAMATAN MIKROSKOPIS Liana Liana; Prihatini Prihatini
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 13, No 1 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v13i1.897

Abstract

Test for occult blood in faeces is an important part of the early detection of colorectal cancer, gastrointestinal bleeding, and anaemia.Colorectal cancer is the second leading cause of cancer deaths in the United States. Immunochemistry method for detection of humanhaemoglobin in faeces has been developed. The advantages of this method are improving analytical sensitivity and specificity, alsoavoiding the dietary restrictions requirement, compared with benzidine test, and guaiacum test. A study was performed to correlate theresult of fecal occult blood by immunochemistry method using anti-human haemoglobin and microscopic examination of red blood cellsin faeces of outpatients in the Clinical Pathology Laboratory, Dr. Soetomo Hospital, Surabaya. Faeces of fifty one patients tested for fecaloccult blood were examined by immunochemistry method compared with microscopic examination of red blood cells. Comparison ofthe two methods was done by statistical analysis, Mc Nemar test. The correlation was measured using ROC curve. The results showed acorrelation between immunochemistry method and microscopic examination with average red blood cells (RBC) ≤ 2/hpf, p = 0.008; RBC≥ 3/hpf, p = 0.289. ROC curve showed r = 0.941. In conclusion, a significant correlation between positive results of immunochemistrymethod and microscopic examination with average red blood cells ≥ 3/hpf. Further research using larger and more representativesamples should be carried out.
PERBANDINGAN SEDIAAN BASAH DENGAN SEDIAAN GRAM HAPUSAN SEKRET VAGINA UNTUK DIAGNOSIS BACTERIAL VAGINOSIS P B Notopoero; Prihatini Prihatini
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 13, No 1 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v13i1.888

Abstract

Bacterial vaginosis (BV) is a clinical condition with changes in the vaginal ecosystem. Under normal conditions, the vaginalecosystem contains Lactobacilli microflora but in BV condition, it contains mixed microflora ie combination of anaerobic bacteria andGardnerella sp. There are approximately 300 cases of BV a year in the Dr. Soetomo General Hospital. We can examine vaginal fluidmicroscopically to diagnose BV with wet mount and Gram stain method. Wet mount method is fast to do that clinicians can establishthe diagnosis and therapy earlier. Gram stain method is the gold standard method and more common to do in the laboratory but thestaining method can affect the result. This study aims to know the diagnostic value of wet mount method compared with Gram stainmethod for BV. There were 30 subjects from the Gynaecology Outpatient Clinic in the Dr. Soetomo General Hospital. They presentedwith from the leucorrhoea and fullfiled the clinical criteria for BV. We took the vaginal fluid and examined them with wet mount andGram stain microscopy. The percentage of agreement between wet mount and Gram stain method for BV Grade I is 66%, BV grade IIis 66%, BV grade III is 84.6%, and BV grade IV is 100%. The sensitivity of wet mount method is 85.71%, the specificity is 88.88%, thepositive predictive value and negative predictive value are 94.73% and 72.72%. Based on these data, wet mount method can replaceGram stain method to diagnose BV microscopically in the case that there is not enough time and resource for Gram stain. The wet mountmethod has good sensitivity, specificity, positive and negative predictive value. Wet mount method has a shortcoming in identifying themicroorganism, but this problem can be solved by combining this method with Gram stain method.
KADAR b-hCG PENDERITA MOLA HIDATIDOSA SEBELUM DAN SESUDAH KURETASE Syafii Syafii; S Aprianti; Hardjoeno Hardjoeno
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 13, No 1 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v13i1.877

Abstract

Hydatiform mole is an important disease, with a high incidence, many risk factors, and equity spreading. To know and compareb-hCG levels among patients with hydatiform mole before and after curretage was investigated. A retrospective study from January2002 to December 2005 at Dr. Wahidin Sudirohusodo Public Hospital was performed comprising b-hCG levels of hydatiform molepatients before and after curettage. b-hCG level (Elisa’s method) were grouped by age of pregnancy. Among 72 patients, 43 patients withhydatiform mole were found. At trimester I among 10 patients (23.3%), b-hCG level was higher 3 (7.0%), normally 4 (9.3%) and lower3 (7.0%). At trimester II, among 33 patients (76.7%), b-hCG level was higher 12 (27.9%), normal 13 (30.2%) and lower 3 (7.0%).After curretage, b-hCG level was decreased in 35 (81.4%), and increased in 7 (16.3%). Diagnosis of hydatiform mole was establishedin 36 (83.7%) and Gestational Trophoblastic Tumours (GTT) 7 (16.3%). Patients with hydatiform mole had the highest incidence intrimester II with normal b-hCG level and b-hCG level decreased after curretage.
FAKTOR PATOGENESIS DAN DIAGNOSIS PENYAKIT von Willebrand R Sindunata; M. Y. Probohoesodo
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 13, No 1 (2006)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v13i1.895

Abstract

von Willebrand disease (vWD) is an autosomal inherited bleeding disorder caused by a deficiency or abnormality of von Willebrandfactor (vWF). vWF is a large multimeric glycoprotein that mediates platelet adhesion at the site of vessel injury. It also protects factorVIII from proteolytic degradation in the circulation. vWD has a prevalence of about 1% in the general population but less than 10%have bleeding symptoms. Bleeding symptoms are usually mucocutaneous and post surgical with varying severity. This disorder canresult from either a quantitative (types 1 and 3) or qualitative (type 2) defect in vWF. Type 2 vWD has been further classified into fourdistinct subtypes; 2A, 2B, 2M and 2N. The diagnosis of vWD requires attention to personal and family history of excessive bleeding andconfirmation by laboratory evaluation. A mild chronic thrombocytopenia is often seen in type 2B vWD. Patients with mild vWD oftenhave both a normal bleeding time and normal APTT. Specific tests for vWD diagnosis involve vWF antigen level, vWF activity (ristocetincofactor), and factor VIII activity. Once a diagnosis is established, additional tests that aid in classifying the type of vWD includeristocetin-induced platelet aggregation and vWF multimer analysis.

Page 1 of 1 | Total Record : 10

 1 

Filter by Year

2006 2006


Reset
Filter By Issues
All Issue Vol. 32 No. 1 (2025) Vol. 31 No. 3 (2025) Vol. 31 No. 2 (2025) Vol. 31 No. 1 (2024) Vol. 30 No. 3 (2024) Vol. 30 No. 2 (2024) Vol. 30 No. 1 (2023) Vol. 29 No. 3 (2023) Vol. 29 No. 2 (2023) Vol 29, No 1 (2022) Vol. 29 No. 1 (2022) Vol. 28 No. 3 (2022) Vol 28, No 3 (2022) Vol. 28 No. 2 (2022) Vol 28, No 2 (2022) Vol. 28 No. 1 (2021) Vol 28, No 1 (2021) Vol. 27 No. 3 (2021) Vol 27, No 3 (2021) Vol. 27 No. 2 (2021) Vol 27, No 2 (2021) Vol 27, No 1 (2020) Vol. 27 No. 1 (2020) Vol 26, No 3 (2020) Vol. 26 No. 3 (2020) Vol 26, No 2 (2020) Vol. 26 No. 2 (2020) Vol 26, No 1 (2019) Vol. 26 No. 1 (2019) Vol 25, No 3 (2019) Vol. 25 No. 3 (2019) Vol. 25 No. 2 (2019) Vol 25, No 2 (2019) Vol. 25 No. 1 (2018) Vol 25, No 1 (2018) Vol. 24 No. 3 (2018) Vol 24, No 3 (2018) Vol. 24 No. 2 (2018) Vol 24, No 2 (2018) Vol 24, No 1 (2017) Vol. 24 No. 1 (2017) Vol. 23 No. 3 (2017) Vol 23, No 3 (2017) Vol 23, No 2 (2017) Vol. 23 No. 2 (2017) Vol 23, No 1 (2016) Vol 22, No 3 (2016) Vol 22, No 2 (2016) Vol 22, No 1 (2015) Vol 21, No 3 (2015) Vol 21, No 2 (2015) Vol 21, No 1 (2014) Vol 20, No 3 (2014) Vol 20, No 2 (2014) Vol 20, No 1 (2013) Vol 19, No 3 (2013) Vol 19, No 2 (2013) Vol 19, No 1 (2012) Vol. 19 No. 1 (2012) Vol. 18 No. 3 (2012) Vol 18, No 3 (2012) Vol 18, No 2 (2012) Vol 18, No 1 (2011) Vol. 18 No. 1 (2011) Vol 17, No 3 (2011) Vol 17, No 2 (2011) Vol 17, No 1 (2010) Vol 16, No 3 (2010) Vol 16, No 2 (2010) Vol 16, No 1 (2009) Vol 15, No 3 (2009) Vol 15, No 2 (2009) Vol 15, No 1 (2008) Vol 14, No 3 (2008) Vol 14, No 2 (2008) Vol 14, No 1 (2007) Vol 13, No 3 (2007) Vol 13, No 2 (2007) Vol 13, No 1 (2006) Vol 12, No 3 (2006) Vol 12, No 2 (2005) Vol 12, No 1 (2005) More Issue