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Andalas obstetrics and gynecology journal
Published by Universitas Andalas
ISSN : 25798324     EISSN : 25798413     DOI : https://doi.org/10.25077/aogj
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Nursing Public Health
Andalas Obstetrics And Gynecology Journal (AOJ) (e-ISSN: 2579-8324) is a peer-reviewed, open-access national journal published by Universitas Andalas and is dedicated to publish and disseminate research articles, literature reviews, and case reports, in the field of obstetrics, gynecology, and other related disciplines.
Arjuna Subject : Kedokteran - Obstetrics and Gynaecology
Articles 9 Documents
 1 
Search results for , issue "Vol. 2 No. 1 (2018)" : 9 Documents clear
ISOLATION OF AMNIOTIC FLUID MESENCHYMAL STEM CELLS (AF MSCs) OBTAINED FROM CAESAREAN SECTIONS Utama, Bobby Indra
Andalas Obstetrics And Gynecology Journal Vol. 2 No. 1 (2018)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.1-9.2018

Abstract

Amniotic fluid is a liquid that fills the amniotic cavity which has defense and nutritional functions in fetal development. Human aterm amniotic fluid can be an ideal alternative as a source of mesenchymal stem cells, originating from the neonate. Preclinical studies of second and third trimester amnion fluid cells confirmed the number of potential donors from this wasted material. In several studies, AF-MSCs express mesenchymal markers such as CD90, CD73 (SH3, SH), CD105 (SH2), CD29, CD166, CD49e, CD58 and CD44 (MHC class I). These cells also express HLA-ABC antigens, CD 34, CD 45 which are hematopoietic markers, and endothelial CD31 markers. There is no expression of CD10, CD11b, CD14, CD34, CD117, EMA and HLA-DR, DP, DQ antigens. Most of AF-MSCs have pluripotent properties which are characterized by the discovery of octamer binding protein 3/4 (Oct-3/4), transcription factors Nanog (Nanog), and stage-specific embryonic antigen 4 (SSEA-4) on RT-PCR examination. From this study, 8 million cells was isolated. These cells will be used for research on pelvic organ prolapse therapy by using AF-MSCs. AF-MSCs isolation totally takes 6 weeks. From 1 flask, 2 million of stem cells was obtained. Keywords: amniotic fluid, AF-MSCs
PERBEDAAN RERATA FAKTOR HEMOSTASIS PADA PREEKLAMPSIA BERAT DAN EKLAMPSIA Setia, Dyhan Purna; Ferry, Ferdinal; Djanas, Dovy
Andalas Obstetrics And Gynecology Journal Vol. 2 No. 1 (2018)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.10-15.2018

Abstract

Objective : To find the difference in mean hemostatic factors in severe preeclampsia and eclampsia.Method : The study was analytic descriptive using a cross sectional study design by looking at the subject's Medical Record according to the time and place of research. The sample is the entire medical record of pregnant women who suffer from preeclampsia and eclampsia in the obstetric and gynecology departments of Dr. M. Djamil Padang Hospital in the period 15 January 2016 to 31 December 2017. The assessment was in the form of assessed platelet levels, PT, APTT and D-Dimer. Samples were taken from populations that met the inclusion criteria and did not have exclusion criteria. Sampling using consecutive sampling techniques taken from the Medical Record Dr. M.Djamil Padang. Statistical analysis to assess significance using the T-Test.Result : The severity the condition of pregnancy the lower the platelet mean and PT. Significant differences were obtained between platelets in PEB and eclampsia (p> 0.05). The mean PT, APTT and D-Dimer showed no significant differences in pregnancy conditions. Statistical test with T-Test did not show significant differences in mean PT, APTT, and D-dimer between eclampsia and PEB (p> 0.05).Conclusion : There were significant differences in mean in platelets, whereas in PT, APTT, and D-dimers in PEB and eclampsia there were no significant differences.Keywords: Pregnancy, severe preeclampsia, eclampsia, platelets, PT, APTT, D-Dimer.
PERBEDAAN RERATA KADAR NATRIUM MATERNAL ANTARA PREEKLAMPSIA BERAT DAN EKLAMPSIA DI RSUP DR. M. DJAMIL PADANG Efri, Gunawan; Djanas, Dovy
Andalas Obstetrics And Gynecology Journal Vol. 2 No. 1 (2018)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.16-20.2018

Abstract

Objective: To determine the difference in mean ratio of sodium content between pregnancy with severe preeclampsia and eclampsia.Method: This is an analytical study using a cross sectional study design. The study was conducted inMaternity room of Dr. M. Djamil Padang from January 15th, 2016 to December 31st, 2017, there were 60 patients as subjects, the sample was divided into 2 groups: severe preeclampsia and eclampsia. Furthermore, history and physical examination to obtain data and clinical diagnosis. Data is recorded in a research form that has been provided, then performed blood electrolytes of Sodium and Potassium. Statistical analysis to assess significance using T-test.Results: In the severe preeclampsia and eclampsia, multiparous parity had the highest respondent. This is consistent with the literature in which the incidence of preeclampsia is more common in late pregnancy.Conclusions: There was no significant difference in the mean sodium ratio between normal severe preeclampsia pregnancy and normal pregnancy.Keywords: pregnancy condition, severe preeclampsia, eclampsia, and sodium.
PERBEDAAN KADAR ASAM FOLAT SERUM PENDERITA ABORTUS SPONTAN DENGAN KEHAMILAN NORMAL Ermawati, Ermawati; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 2 No. 1 (2018)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.53-61.2018

Abstract

Abortion is the termination of pregnancy before fetus can survive in the outside world, regardless of the cause. One cause of spontaneous abortion due to maternal nutritional factors, such as folic acid defi-ciency, lead to disruption of cell function and ends with apoptosis as well as continuing with fetal death. The study was conducted to determine differences in the levels of folic acid serum between patients with normal pregnancy and spontaneous abortion in some hospitals in West Sumatra. The study was con-ducted by the method of analytic observational comparative cross-sectional design. This research was carried out on pregnant women who come to the clinic and emergency obstetric Dr.M.Djamil hospital Padang, Batusangkar Hospital, Reksodiwiryo Hospital Padang and examinations conducted in biomed-ical laboratory medical faculty Andalas University the period August-December 2014. The total number of women included in the statistical calculation after the inclusion and exclusion criteria are met is 54 people, statistical analysis was done afterwards. The mean levels of serum folic acid is lower in sponta-neous abortion patients compared with average levels of folic acid in normal. Results of statistical anal-ysis using t-test found significant differences in the mean serum levels of folic acid group of spontaneous abortion patients with normal pregnancy group, it can be seen from p-value 0.001 (p <0.05).Keywords: Spontaneous abortion, folic acid, fetus death
OMPHALOCELE Nafis, Muhammad Johar; Yusrawati, Yusrawati
Andalas Obstetrics And Gynecology Journal Vol. 2 No. 1 (2018)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.62-66.2018

Abstract

Objective: Reporting a case of omphalocele.Method: Case report.Result: A case of a 24 years-old woman, diagnosed with G1P0A0H0 37-38 weeks of term pregnancy + omphalocele. According to ultrasonography, biometric measurements of the fetus were: BPD: 8.4 cm, FL: 6.7 cm, HL: 5.9 cm, AC: 30.5 cm, AFI: 8.7 cm, there were no image of abdominal wall, but a membrane surrounding the abdomen was visible. From the USG examination, the conclusion was Omphalocele. Chromosomal analysis was done using G-Comparative technic, with result 46, XY, which means the amount of the chromosomes was 46, and sex chromosomes were XY. There was no major structural defect. Mostly, the disorders causing these conditions are 13, 18 and 21 trisomy, and Beckwith-Wiedemann Syndrome.Conclusion: Omphalocele is a genetic disorder marked by failure of the abdominal organs to return into the abdominal cavity. It requires thorough and accurate prenatal examinations to establish a diagnosis.Keywords: Omphalocele, prenatal diagnosis
HUBUNGAN ANTARA USIA, PARITAS, PEKERJAAN DAN INDEK MASSA TUBUH DENGAN KEJADIAN PROLAP ORGAN PANGGUL BERDASARKAN SKOR PELVIC ORGAN PROLAPSE QUANTIFICATION Ermawati, Ermawati; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 2 No. 1 (2018)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.37-43.2018

Abstract

Pelvic organ prolapse is a condition that affects the quality of women life. Pelvic organ prolapse can be caused by injury until the birth process, the aging process, the composition of the tissue in a woman, a chronic cough, or often do heavy work. Early detection of prolapse associated with Prognosis of anatomy and functional pelvic organs recovery. So we need training and learning more about Pelvic Organ Prolapse Quantification (POPQ) are clearly. The study was conducted by the method of case control study in the department of OB polyclinic of Dr. M. Djamil Padang Hospital from September 2013 until the total sample of 98 patients with 49 control groups and 49 in the case group. Analyzes were connected to assess the association of age, parity, occupation and body mass index with the incidence of pelvic organs prolapse based on POPQ. Score data are presented in tabular form. Data were tested by t-test and chi square test. If p <0.05 indicates significant results. There is a significant relationship between age and the incidence of pelvic organ prolapse (p <0.05) and OR 27,871. there is a significant correlation between parity and the incidence of pelvic organ prolapse (p<0.05) and OR 52,970. From the statistical analysis of the work, it cannot be tested statistically. From the body mass index, there is no significant relationship to the occurrence of pelvic organ prolapse (P> 0.05) and OR 1:00.Keywords: age, parity, occupation, body mass index, pelvic organs prolapse
PERBEDAAN KADAR ZINC SERUM PENDERITA PREEKLAMPSIA BERAT DENGAN KEHAMILAN NORMAL Ermawati, Ermawati; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 2 No. 1 (2018)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.44-52.2018

Abstract

Preeclampsia is a major obstruction complication with increasing incidence and is associated with maternal morbidity and mortality. One theory regarding preeclampsia is the development of oxidative stress due to the benefits of pro-oxidant and anti-oxidant functions that consequently results in free radicals, active oxygen, or reactive nitrogen. The deacrease of Zinc as a cofactor of anti-oxidant enzymes is reported to be associated with an increased risk of preeclampsia. Cross sectional comparative study was conducted in Dr. M. DjamilPadangHospital, SolokDistrict Hospital, PainanDistrict Hospital, BatusangkarDistrict Hospital, and Biomedicallaboratoryof Medical Faculty of Andalas University from September 2014 to February 2015. There were 40 samples with pregnancy beyond 20 weeks which were then divided into two groups; severe preeclampsia and normal pregnancy. Serum zinc wasexamined in both groups. Serum zinc in severe preeclampsia and normal pre-stressed demonstrated a significant difference (p <0.05). The mean concentration of serum zinc in severe preeclampsia and in normal pregnancy were 0.45 ± 0.09 μg / ml and 0.78 ± 0.55 μg / ml with p = 0.02. This difference is statistically significant with p <0.005. There was a significant difference between serum zinc concentration in normal pregnant women and that in severe preeclamptic women.Keywords: severe preeclampsia, normal pregnancy, zinc serum
Pengaruh peningkatan dosis kalsium terhadap tekanan darah pada ibu hamil di RSUP Dr Mdjamil Padang Ariadi, Ariadi; Azmi, Syaiful; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 2 No. 1 (2018)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.26-36.2018

Abstract

Until recently, the exact etiology and pathophysiology of preeclampsia have not been discovered yet, but based on the clinical symptoms and the defect that appeared, researchers submitted some ways as assumption or as early detection of preeclampsia and eclampsia. Some researchers have suggested the examination of calcium / creatinine excretion ratio in urine from preeclampsia patients as the result of kidney's function changes. This study has been performed with a pre and post test group design experimental method at Obstetric and Gynecology Polyclinic in RS. Dr. M. Djamil Padang and several midwife private practices in Padang since July 2013 until the samples reached the quantity up to 40 samples. Analysis has been done to describe the relationship between calcium intake and blood pressure. Furthermore, we analyzed the differences of systolic - diastolic and MAP before and after calcium intake. Data has been shown on the table and analyzed by Pearson correlation, Wilcoxon test and Paired T test. if p <0.05, it shows a significant result. The mean of systolic after calcium intake was the same for both of the groups (121.5 + 8.02: 121.5 + 6.71). Mean of diastolic after calcium intake in controls group was lower than trials group (75.9 + 4.32: 75.9 + 4.32). Mean of MAP after calcium intake for controls group was lower that trials group (91,088 + 4.47: 91,956 + 6.08). There is an influence of calcium intake on decreasing maternal blood pressure. The mean of systolic after calcium intake was the same for both of the groups (121.5 + 8.02: 121.5 + 6.71). Mean of diastolic after calcium intake in controls group was lower than trials group (75.9 + 4.32: 75.9 + 4.32). Mean of MAP after calcium intake for controls group was lower that trials group (91,088 + 4.47: 91,956 + 6.08). There is an influence of calcium intake on decreasing maternal blood pressure. The mean of systolic after calcium intake was the same for both of the groups (121.5 + 8.02: 121.5 + 6.71). Mean of diastolic after calcium intake in controls group was lower than trials group (75.9 + 4.32: 75.9 + 4.32). Mean of MAP after calcium intake for controls group was lower that trials group (91,088 + 4.47: 91,956 + 6.08). There is an influence of calcium intake on decreasing maternal blood pressure.Keywords: Systolic, Diastolic, Mean Arterial Pressure (MAP)
HUBUNGAN LAMANYA PEMBERIAN MAGNESIUM SULFATE PADA PASIEN PEB DAN EKLAMPSIA DENGAN KEJADIAN HIPERMAGNESIUM DI RSUP DR. M. DJAMIL PADANG Mayuliani, Mayuliani; Djanas, Dovy
Andalas Obstetrics And Gynecology Journal Vol. 2 No. 1 (2018)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.21-25.2018

Abstract

Objective :To find out the relationship between the duration of MgS04 administration in severe preeclampsia patients and eclampsia with the incidence of hypermagnesium.Method :This study is a comparative observational study using a cross sectional study design. The study was conducted in the medical record of Dr.M.Djamil Padang Hospital during the period January 1, 2016 to August 31, 2017 of pregnant women with severe preeclampsia and eclampsia, found 30 study subjects who met the inclusion criteria. Furthermore, data is recorded in a research form that has been provided, then carried out research data processing. Statistical analysis to assess significance using the chi-square test.Results : Magnesium levels increased in pregnant women with severe preeclampsia and eclampsia by 21 correspondents. Increased Magnesium levels in patients with severe preeclampsia and eclampsia who received MgS04 treatment for 48 hours by 16 correspondents (84.2%) and 5 correspondents with MgS04 administration for 24 hours.Conclusion : There is a significant relationship between the duration of Magnesium Sulfate with the incidence of hyperpermagnesium in patients with severe preeclampsia and eclampsia. Keywords: severe preeclampsia, eclampsia, magnesium sulfate, magnesium levels

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