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Putranto Manalu
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INDONESIA
Jurnal Prima Medika Sains
Published by Universitas Prima Indonesia
ISSN : 26863502     EISSN : 27146707     DOI : https://doi.org/10.34012/jpms
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal Prima Medika Sains adalah jurnal ilmiah di bidang kesehatan dan kedokteran yang terbit dua kali dalam setahun yaitu pada bulan Juni dan Desember. Diterbitkan oleh Universitas Prima Indonesia yang secara teknis dikelola Program Studi Magister Kesehatan Masyarakat Fakultas Kedokteran Universitas Prima Indonesia. Berisi tulisan hasil penelitian lapangan atau laboratorium maupun studi pustaka di bidang kesehatan dan kedokteran.
Arjuna Subject : Kedokteran - Kesehatan Masyarakat, Kesehatan Lingkungan dan Pekerjaan
Articles 25 Documents
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Search results for , issue "Vol. 5 No. 2 (2023): December" : 25 Documents clear
Non-pharmacological treatments in cancer pain management Edlin, Edlin; Lina, Juliana; Nazara, Novita Mirna Sari
Jurnal Prima Medika Sains Vol. 5 No. 2 (2023): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i2.4595

Abstract

Non-pharmacological therapies have recently become the focus of attention in many countries, including pain management in patients with cancer. This study aimed to explore the latest scientific evidence regarding pain management using non-pharmacological therapies in patients with cancer. The method used was a scoping review using the PRISMA-ScR framework. A literature search was conducted using four databases: PubMed, DOAJ, and Google Scholar, and published in the range of 2018-2023. There of 992 potentially relevant articles and 10 eligible articles were selected. The results of the study showed that nonpharmacological therapy was effective in reducing the pain scale in cancer patients based on the significant value and effect size of providing interventions to patients.
Opioid and the usage in chronic non cancer pain Simbolon, Boyke Marthin
Jurnal Prima Medika Sains Vol. 5 No. 2 (2023): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i2.4613

Abstract

The use of opioid in various guidelines for chronic non-cancer pain is controversial because evidence of their long-term benefits is weak. The potential for serious adverse effects and local regulations warrant caution in both prescribers and users. However, opioids have a role in the management of chronic non-cancer pain in carefully selected patients with regular monitoring and as a part of multimodal therapy. Common adverse effects should be treated promptly to improve patient compliance. We believe that opioid therapy at low doses is beneficial in some patients. It should not be denied but carefully considered on a case-by-case basis.
Antibiotics self-medication practices among students in Universitas Prima Indonesia Novriani, Erida; Neswita, Elfia; Razoki, Razoki
Jurnal Prima Medika Sains Vol. 5 No. 2 (2023): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i2.4622

Abstract

The irrational use of antibiotics can endanger health by causing unwanted drug reactions, side effects, and drug resistance. This study aimed to analyze the patterns of antibiotic self-medication among university students. This descriptive cross-sectional study was conducted at Prima Indonesia University in October 2023. A total of 307 randomly selected students from various faculties (health science clumps and non-health science clumps) filled out questionnaires distributed via Google Forms. The collected data are then analyzed descriptively to obtain frequency and percentage data, which are then presented in the form of tables and narratives. The results showed that about 83.39% of respondents had used antibiotics before. Most respondents used antibiotics because they were easily available (43.36%) or because of their previous experience (36.72%). The most common conditions for antibiotic use were cough and cold (47.66%), and infections (23.05%). Most respondents used antibiotics based on doctor ’sor pharmacist’s recommendations (45.31%). The duration of antibiotic use was 1-3 days (61.72%), followed by 4-7 days (31.64%) and more than 7 days (6.64%). Antibiotics were purchased from pharmacies (83.20%). The most common reactions to the overuse of antibiotics were nausea and vomiting (40.23%) and headache (32.81%). Most respondents (53.13%) consulted a doctor or pharmacist if they experienced reactions to antibiotic overuse.
The effect of moringa flower extract on kidney function in obese rats Meri, Meri; Lawrence, Christopher; Wilsen, Wilsen
Jurnal Prima Medika Sains Vol. 5 No. 2 (2023): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i2.3952

Abstract

This study aims to measure the effect of moringa flower extract administration on kidney function and histopathological features of the kidneys of obese male Wistar puith galir rats. This research is a type of experimental quantitative research using post-test only group design. This research was conducted at the Department of Pharmacy Pharmacology Laboratory, Faculty of Medicine, University of North Sumatra and Anatomical Pathology Laboratory, University of North Sumatra. Histopathology observation of kidney tissue was done by comparing the control and treatment groups. Changes observed will be the presence of fatty degeneration (vacuolization), necrosis and hydrophic degeneration. To obtain quantitative data, scoring was performed on each change found. The research data were tabulated and then the changes found were analyzed and presented descriptively. The research data were then analyzed with the help of SPSS version 25.0. The data normality test was analyzed with the Kolmogorov-Smirnov test approach (p> 0.05). To test the significance between test groups, one-way analysis of variance or One Way ANOVA technique was conducted at 95% confidence level (p < 0.05). Further analysis or test was conducted using Post Hoc Test with LSD technique. The results of the analysis showed that the administration of Moringa flower extract at a dose of 600 mg/KgBB was effective in improving kidney function in obese Wistar white rats. This improvement can be seen through the levels of ureum, creatinine, and histological structure of the kidneys that have improved. The results of histopathological observations of kidney tissue in treatment group 3, namely moringa flower extract at a dose of 600 mg/KgBB, experienced the most significant improvement and approached the control group compared to other groups.
The effect of binahong leaf extract on cardiac function in rats fed a high-fat diet Wahyudi, Dwi Sukma; Sartika, Dewi; Harahap, Alvin Abrar
Jurnal Prima Medika Sains Vol. 5 No. 2 (2023): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i2.4067

Abstract

Several antioxidant defense mechanisms protect biological systems from the negative impact of ROS. Natural antioxidants are mainly obtained from plants, such as vegetables, and one of them is the binahong plant which is rich in antioxidants. This plant is often used traditionally as a blood-thinning drug to prevent stroke. This study aimed to evaluate the effect of binahong (anderera cardifolia) leaf extract on cardiovascular health and the histological structure of the heart of wistar male white rats fed a high-fat diet. This study is an experiment with a completely randomized design (CRD) consisting of 4 groups: normal control, treatment 1 dose 200 mg/kg BW, treatment 2 dose 300 mg/kg BW, and treatment 3 dose 400 mg/kg BW. Histopathological data such as aortic wall thickness and number of foam cells were analyzed using SPSS 23 with one-way ANOVA test and Post Hoc LSD at 0.05 significance level. The results showed that administering a dose of 400 mg/kg BW effectively reduced the thickness of the aortic wall and the number of aortic foam cells in rats.

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