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Detection of glibenclamide adulteration in herbal remedies for diabetes mellitus using TLC Budi, Andre; Razoki, Razoki; Harahap, Halimah; Amansyah, Adek; Edlin, Edlin; Tarigan, Susiani
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 1 (2024): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i1.5287

Abstract

The widespread use of jamu, a traditional Indonesian herbal medicine, has been accompanied by a surge in adulteration with synthetic drugs to enhance efficacy and sales. This study aimed to detect the presence of glibenclamide, a common adulterant, in antidiabetic jamu product using TLC. This study employed three herbal medicine samples marketed for lowering blood glucose levels, with glibenclamide BPFI serving as a reference standard. Thin-layer chromatography, employing a mobile phase consisting of chloroform, cyclohexane, ethanol, and glacial acetic acid (9:9:1:1), was utilized for the analysis. Thin-layer chromatography (TLC) analysis revealed a standard Rf value of 0.4 for glibenclamide, producing a distinct blue-violet spot when visualized with 10% sulfuric acid. The results indicated that the tested herbal medicine samples did not contain the pharmaceutical substance glibenclamide. This conclusion was drawn from the absence of a corresponding Rf value for glibenclamide in the herbal samples when compared to the reference standard.
Pengaruh daya tanggap dan kehandalan terhadap kepuasan pasien umum rawat jalan di RSU Royal Prima Medan Bu'ulolo, Christian Siuwandy; Edlin, Edlin; Suyono, Tan; Girsang, Ermi
Jurnal Prima Medika Sains Vol. 1 No. 1 (2019): Desember
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (329.144 KB)

Abstract

Data kunjungan pasien umum rawat jalan RSU Royal Prima Medan pada bulan Februari - Agustus 2018 menunjukkan bahwa adanya penurunan jumlah kunjungan pasien umum rawat jalan. Penurunan jumlah kunjungan pasien tersebut dipengaruhi berbagai faktor, salah satunya adalah mutu pelayanan kesehatan yang mengakibatkan ketidakpuasan pasien terhadap pelayanan rumah sakit. Penelitian ini bertujuan untuk menganalisis pengaruh daya tanggap dan kehandalan terhadap kepuasan pasien umum rawat jalan di RSU Royal Prima Medan dengan jenis penelitian kuantitatif dan pendekatan cross-sectional dan jumlah responden sebanyak 89 orang dengan menggunakan teknik accidental sampling. Analisis data dengan menggunakan uji regresi linear berganda. Hasil penelitian menunjukkan terdapat pengaruh yang signifikan antara mutu pelayanan sebesar 97,2 % kepuasan pasien dengan signifikansi sebesar 0.000 (p<0.05). Terdapat pengaruh positif dan signifikan antara variabel kehandalan dengan nilai signifikan 0,0028 terhadap kepuasan pasien umum rawat jalan di RSU Royal Prima Medan.
Neural Proloterapi Edlin, Edlin; Wirawan, Nur Surya
Jurnal Prima Medika Sains Vol. 4 No. 2 (2022): Desember
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v4i2.3162

Abstract

Terapi nyeri dengan injeksi regeneratif merupakan terapi yang mulai berkembang dengan pesat dalam kurun waktu ini. Ilmu pengetahuan dasar dan penelitian klinis terbaru menunjukkan kalau injeksi larutan dekstrosa dapat mengurangi rasa sakit, meningkatkan fungsi keseluruhan dan mengembalikan fungsi jaringan ikat yang rusak kembali menjadi normal. Walaupun mekanisme aksi dekstrosa belum dipahami dengan baik pada tingkat sel, uji klinis telah melaporkan efek klinis positif dibandingkan dengan kontrol injeksi buta. Salah satu teknik regenerasi aktif injeksi yang mulai dilirik para peneliti adalah neural proloterapi (NP). Berbagai penelitian dan laporan kasus mulai bermunculan dan menunjukkan bahwa NP dapat dilakukan baik sebagai penanganan alternatif maupun penanganan utama dalam berbagai kasus penyakit dan berbagai kondisi yang disertai nyeri kronik. Keuntungan utama pendekatan teknik NP selain memerlukan biaya yang murah, tingkat keamanan yang tinggi dan kemudahan teknik juga dapat dipertimbangkan.
Non-pharmacological treatments in cancer pain management Edlin, Edlin; Lina, Juliana; Nazara, Novita Mirna Sari
Jurnal Prima Medika Sains Vol. 5 No. 2 (2023): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i2.4595

Abstract

Non-pharmacological therapies have recently become the focus of attention in many countries, including pain management in patients with cancer. This study aimed to explore the latest scientific evidence regarding pain management using non-pharmacological therapies in patients with cancer. The method used was a scoping review using the PRISMA-ScR framework. A literature search was conducted using four databases: PubMed, DOAJ, and Google Scholar, and published in the range of 2018-2023. There of 992 potentially relevant articles and 10 eligible articles were selected. The results of the study showed that nonpharmacological therapy was effective in reducing the pain scale in cancer patients based on the significant value and effect size of providing interventions to patients.
Profile of urinary tract infections in the Urology Polyclinic of Imelda Pekerja Indonesia General Hospital Matondang, Lasma Ani Giot Marito; Ade Indra Mukti; Edlin, Edlin
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5807

Abstract

Urinary tract infection (UTI) is one of the most common infectious diseases in the world, affecting 150 million people every year.The purpose of this study was to determine the profile of urinary tract infection patients in the urology polyclinic at Imelda Pekerja Indonesia General Hospital.The type of research used in this study was observational analytic with a cross sectional study design. In this study, the population and sample included patients who experienced UTI infection at Imelda Pekerja Indonesia General Hospital. Univariate and bivariate analyses were performed. The results showed that sex was a significant risk factor for UTI. High-risk female gender can increase risk of UTI 4.442 times. Age was not a significant risk factor for UTI. Occupation was not a significant risk factor for UTI. A history of DM was not a significant risk factor for UTI. High-risk patients with a history of DM can increase risk of UTI 1.462 times, this risk was not statistically significant. A history of BSK is a significant risk factor for UTI. High-risk patients with a history of UTI can increase risk of UTI 4.929 times, this risk is statistically significant. Sex and a history of BSK were significant risk factors for UTI. Age, occupation, and history of DM were not significant risk factors for UTI.
Common injuries among Brazilian Jiu Jitsu practitioners in Medan City Lazuardi, Maulana Umar; Edlin, Edlin; Mukti, Ade Indra
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5727

Abstract

Brazilian Jiu Jitsu (BJJ) is a martial art that focuses on floor fighting and was first popularized in Brazil. The BJJ originally focused on entertainment, health, and self-development. These goals changed when practitioners began participating in competitions in which there was a significant increase in the number of BJJ injuries. A pre-survey in the field indicated that many jiu jitsu practitioners were affected by common injuries. The type of research in this study is a descriptive survey with a cross-sectional approach conducted at Ryu Dojo Martial Arts Center, Musi Jiu Jitsu, and PBJI Medan City in March 2024. Data were collected in the form of questionnaires, interviews, and medical records of practitioners diagnosed with injuries who were sampled. Univariate analysis was used to obtain the frequency distribution of respondents for each variable, namely age, gender, belt level, weight, training frequency, and competitor status. The results of the study were analyzed using SPSS version 27.0. The results showed that the highest number of practitioners was in the late teenage group (53.8%), the highest gender was male (92.3%), and the highest number of practitioners was white belt (69.2%). Based on body weight, the highest number of practitioners was in the Light Feather category (< 64 kg/141 lbs) with a percentage of 26.9%, and the most training hours were 3-5 hours 16 (30.8%). Lower Back Pain was the most common injury with a total of 25 practitioners. A total of 75% of the practitioners stated that their daily activities were disrupted because of their injuries. It can be concluded that the majority of BJJ participants were in their late teens, male was the most common gender, and white belts were the most common practitioners. The most common injury was lower back pain due to the amateur competitor status. Most respondents stated that their injuries interfered with their daily activities.
Detection of glibenclamide adulteration in herbal remedies for diabetes mellitus using TLC Budi, Andre; Razoki, Razoki; Harahap, Halimah; Amansyah, Adek; Edlin, Edlin; Tarigan, Susiani
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 1 (2024): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i1.5287

Abstract

The widespread use of jamu, a traditional Indonesian herbal medicine, has been accompanied by a surge in adulteration with synthetic drugs to enhance efficacy and sales. This study aimed to detect the presence of glibenclamide, a common adulterant, in antidiabetic jamu product using TLC. This study employed three herbal medicine samples marketed for lowering blood glucose levels, with glibenclamide BPFI serving as a reference standard. Thin-layer chromatography, employing a mobile phase consisting of chloroform, cyclohexane, ethanol, and glacial acetic acid (9:9:1:1), was utilized for the analysis. Thin-layer chromatography (TLC) analysis revealed a standard Rf value of 0.4 for glibenclamide, producing a distinct blue-violet spot when visualized with 10% sulfuric acid. The results indicated that the tested herbal medicine samples did not contain the pharmaceutical substance glibenclamide. This conclusion was drawn from the absence of a corresponding Rf value for glibenclamide in the herbal samples when compared to the reference standard.
Common injuries among Brazilian Jiu Jitsu practitioners in Medan City Lazuardi, Maulana Umar; Edlin, Edlin; Mukti, Ade Indra; Napitu, Sabar Hamonangan Victoranius; Setiawan, Deni
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5727

Abstract

Brazilian Jiu Jitsu (BJJ) is a martial art that focuses on floor fighting and was first popularized in Brazil. The BJJ originally focused on entertainment, health, and self-development. These goals changed when practitioners began participating in competitions in which there was a significant increase in the number of BJJ injuries. A pre-survey in the field indicated that many jiu jitsu practitioners were affected by common injuries. The type of research in this study is a descriptive survey with a cross-sectional approach conducted at Ryu Dojo Martial Arts Center, Musi Jiu Jitsu, and PBJI Medan City in March 2024. Data were collected in the form of questionnaires, interviews, and medical records of practitioners diagnosed with injuries who were sampled. Univariate analysis was used to obtain the frequency distribution of respondents for each variable, namely age, gender, belt level, weight, training frequency, and competitor status. The results of the study were analyzed using SPSS version 27.0. The results showed that the highest number of practitioners was in the late teenage group (53.8%), the highest gender was male (92.3%), and the highest number of practitioners was white belt (69.2%). Based on body weight, the highest number of practitioners was in the Light Feather category (< 64 kg/141 lbs) with a percentage of 26.9%, and the most training hours were 3-5 hours 16 (30.8%). Lower Back Pain was the most common injury with a total of 25 practitioners. A total of 75% of the practitioners stated that their daily activities were disrupted because of their injuries. It can be concluded that the majority of BJJ participants were in their late teens, male was the most common gender, and white belts were the most common practitioners. The most common injury was lower back pain due to the amateur competitor status. Most respondents stated that their injuries interfered with their daily activities.
Profile of urinary tract infections in the Urology Polyclinic of Imelda Pekerja Indonesia General Hospital Matondang, Lasma Ani Giot Marito; Ade Indra Mukti; Edlin, Edlin
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5807

Abstract

Urinary tract infection (UTI) is one of the most common infectious diseases in the world, affecting 150 million people every year.The purpose of this study was to determine the profile of urinary tract infection patients in the urology polyclinic at Imelda Pekerja Indonesia General Hospital.The type of research used in this study was observational analytic with a cross sectional study design. In this study, the population and sample included patients who experienced UTI infection at Imelda Pekerja Indonesia General Hospital. Univariate and bivariate analyses were performed. The results showed that sex was a significant risk factor for UTI. High-risk female gender can increase risk of UTI 4.442 times. Age was not a significant risk factor for UTI. Occupation was not a significant risk factor for UTI. A history of DM was not a significant risk factor for UTI. High-risk patients with a history of DM can increase risk of UTI 1.462 times, this risk was not statistically significant. A history of BSK is a significant risk factor for UTI. High-risk patients with a history of UTI can increase risk of UTI 4.929 times, this risk is statistically significant. Sex and a history of BSK were significant risk factors for UTI. Age, occupation, and history of DM were not significant risk factors for UTI.
Health service quality and outpatient hypertension patient satisfaction: A cross-sectional study Olidya, Desyoma; Ginting, Rapael; Siagian, Masryna; Yulizal, OK; Lumbantobing, Christina JRE.; Edlin, Edlin; Fibrini, Dewi
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6755

Abstract

This study aimed to evaluate the impact of healthcare service quality on patient satisfaction among hypertensive outpatients at Muyang Kute Regional General Hospital. Employing a quantitative, cross-sectional design, data were collected from 79 patients using a questionnaire assessing five service quality dimensions (tangibles, reliability, responsiveness, empathy, and assurance) and overall patient satisfaction. Bivariate analysis, utilizing the chi-square test, was conducted to examine relationships between service quality dimensions and patient satisfaction. Results indicated generally positive perceptions of service quality dimensions, with tangibles, reliability, and assurance rated highly. However, empathy and responsiveness showed higher dissatisfaction rates. Notably, only assurance demonstrated a statistically significant association with patient satisfaction (p=0.002), where patients perceiving "Good" assurance were more likely to report satisfaction. Overall patient satisfaction was mixed, with 54.43% reporting satisfaction and 45.57% reporting dissatisfaction. The study highlights the critical role of staff competence and patient confidence (assurance) in driving satisfaction. Recommendations include targeted interventions to improve empathy and responsiveness, continuous monitoring of all service quality dimensions, and further investigation into potential underlying factors affecting overall satisfaction.