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Contact Name
Viskasari P. Kalanjati
Contact Email
majalahbiomorfologi@fk.unair.ac.id
Phone
+6285649348098
Journal Mail Official
majalahbiomorfologi@fk.unair.ac.id
Editorial Address
Departemen Anatomi dan Histologi Fakultas Kedokteran, Universitas Airlangga, Surabaya, Indonesia Jl. Prof Dr Moestopo 47 Surabaya 60132 Indonesia
Location
Kota surabaya,
Jawa timur
INDONESIA
Majalah Biomorfologi (Biomorphology Journal)
Published by Universitas Airlangga
ISSN : 02158833     EISSN : 27160920     DOI : 10.20473/mbiom.v30i1.2020.1-7
Core Subject : Health, Science,
Majalah Biomorfologi publishes articles in the form of original research report, excel-literature review, communication and special case report. The scope of this journal includes Medicine and Health sciences, focusing in basic and applied Anatomy and Histology (i.e., neuroscience, medical and health education, anthropology, clinical genetics, embryology, medical education, clinical anatomy, histotechnics, and photomicroscopy) although other correlated topics are also welcomed.
Arjuna Subject : Kedokteran - Anatomi
Articles 7 Documents
Search results for , issue "Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI" : 7 Documents clear
EFFECTS OF LOW DOSE EXPOSURE OF BORAX FOR 8 WEEKS ON GASTRIC ULCER FORMATION Audi Salman Faza; Linda Dewanti; Ema Qurnianingsih
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (490.038 KB) | DOI: 10.20473/mbiom.v30i1.2020.7-13

Abstract

Background: Borax, a carcinogenic toxicant, is illegally used as food additives frequently. Previous researches shown that high dose of borax exposure (300 mg/kg of BW) caused gastric ulcer, but low dose of borax, as found as usual dose in food, has not been frequently researched. Objective: The aim of this study was to analyze the effects of low dose of borax for 8 weeks on the formation of gastric ulcer. Materials and Methods: Twenty four young adult rats (Rattus norvegicus) were divided into 4 groups (Control, Group 1, 2, and 3). Borax doses of 50 mg/kg, 150 mg/kg, and 300 mg/kg were administered on groups 1, 2, and 3 respectively through sonde for 8 weeks; Control group was not exposed with borax. Body weight was monitored every 2 weeks. On the last day of the experiment, rats were euthanized and gastric ulcers were histopathologically analyzed using a microscope. The data were analyzed by the comparative test of Mann-Whitney and the significancy was set on p<0.050. Results: The results showed that body weight was significantly different on the 6th week between Control vs Group 1 (p=0.010) and Control vs Group 3 (p=0.043). The grade of gastric ulcer was found higher in Group 2 and Group 3 compared to Control (p=0.019 and 0.011 respectively). Conclusion: Both of low dose (150 mg/kg BW) and high dose (300mg/kg BW) of borax exposure for 8 weeks cause microscopic gastric ulcer on rats.
BODY MASS INDEX (BMI) OF CHILDREN WITH TETRALOGY OF FALLOT (TOF) Ovin Nada Saputri; Viskasari P. Kalanjati; Mahrus A. Rahman
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (529.179 KB) | DOI: 10.20473/mbiom.v30i1.2020.14-18

Abstract

Background: Malnutrition is a common cause of morbidity and mortality amongst children with TOF. Objective: To analyze the BMI profile of children with TOF aged 0 – 18 years at Pediatric Department, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Materials and Methods: A cross-sectional study of the BMI from the medical record of TOF patients aged 0 – 18 years at the Pediatric Department, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, since January 2016 to December 2017 was conducted. The data included gender, age group, demographic distribution, weight, and height. BMI was calculated by WHO formula reference; body weight (kg) divided by body height squared (m2), which was converted into z-score histogram. BMI classification was guided by the Government’s Anthropometry Standards for Nutritional Status Assessment. Result: From 84 TOF patients, there were 43 males (51%) and 41 females (49%). The most dominant age group was 0 – 4 years old (n=47;56%). The majority of patients were from outside of Surabaya (n=64;76.2%). Based on their BMI, 36 patients (42.9%) had severe underweight, 10 patients (11.9%) were underweight, and 35 patients (41.7%) were normal, whilst the rests (3.6%) were overweight. Conclusion: The number of male patients was slightly higher than female patients. The majority of TOF patients were 0 – 4 years old and resided out town of Surabaya. The predominant BMI found was the underweight and severe underweight below normal BMI.
EFFECT OF SEX DIFFERENCE ON THE HISTOLOGICAL STRUCTURE OF BRONCHUS AND NASAL CAVITY IN ANIMAL ASTHMA MODEL Reinaldi Rachmadhianto; Tri Hartini Yuliawati; Gatot Soegiarto
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (781.312 KB) | DOI: 10.20473/mbiom.v30i1.2020.19-26

Abstract

Background: The prevalence of asthma in prepuberty women is more common than in puberty men. Even after puberty, to a certain age, women dominate more. It is still unclear whether sex hormones affect the histological structure of male and female airways. Objective: This study objective was to examine the effect of sex difference on the histological structure of bronchial and nasal cavity of mice model (Mus musculus) with ovalbumin exposure. Materials and Methods: This study used 24 mice in four groups (male control, female control, male asthma model, and female asthma model). At the sensitization phase in days 0 and 14, the mice were injected intraperitoneally with 100 μl of a mixture of 50 μl ovalbumin (200 μl/ml) and 50 μl alum. At the exposure phase in days 21 to 23, the mice were exposed to 1% ovalbumin (aerosol, 30 minutes/per day). The mice were sacrificed 48 hours after the last exposure. The data taken included four variables, bronchial epithelial thickness, bronchial smooth muscle thickness, nasal cavity goblet cells number, and nasal cavity mucosal thickness. Then, Shapiro-Wilk normality test and parametric t-test were conducted. Results: In animal asthma models, mice with male and female exposure did not cause differences in epithelial thickness and smooth muscle thickness in bronchus compared to the control group. However, there were significant differences in the number of goblet cells and mucosal thickness in nasal cavity of male and female mice compared to the control group (respectively, p= 0.002; p= 0.006 and p= 0.003; p = 0.005). There were no significant differences between groups of male and female mice on all variables. Conclusion: In animal asthma models of mice, ovalbumin exposure did not cause differences in the values of all variables between male and female groups.
CHARACTERISTIC OF CHRONIC MYELOGENOUS LEUKEMIA PATIENTS AT THE POLYCLINIC OF ONCOLOGY, DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA IN 2017 M. Rifqi Wiyono; Siprianus Ugroseno Yudho Bintoro; Yetti Hernaningsi
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (486.939 KB) | DOI: 10.20473/mbiom.v30i1.2020.27-33

Abstract

Background: Chronic myelogenous leukemia (CML) is a myeloproliferative neoplasm because of the reciprocal translocation of chromosome 22 to chromosome 9. In the United States, the incidence of CML is 1.9 cases per 100,000 people. Whereas in Indonesia, there is no specific national data on CML prevalence, especially regarding the clinical profile, even though the cancer cases reach 1.4 per 1,000 population. Objective: To evaluate the characteristics and clinical features of CML patients in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Materials and Methods: This was a cross-sectional descriptive study with data from the medical records of CML patients in 2017 at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. The sample in this study was CML patients with positive Breakpoint Clusters Region- Abelson (BCR-ABL), having a minimum age of 18 years and equipped with epidemiological data, complete blood count data, and peripheral blood smear data. Results: Thirty-three patients met the study criteria. The sample was predominantly male, with a ratio of 1.06 : 1 to female patients with a median age of 40 years. Spleno-megaly was found in 87.9% of the patients. The average results of leukocyte, platelet, and hemoglobin counts were 254.58 x 103/μL, 557 x 103/μL, and 9.55 g/dL. From the results of peripheral blood smear obtained normochromic normocytic anisopoikilo-cytosis erythrocyte (57.6%), all patients had a profile of increased leukocytes with blast presence in 97% of the patients, and 51.5% had a profile of an increase in platelets and the discovery of giant platelets in 33.3% of the patients. Conclusion: The sample was predominantly male with the highest incidence at a younger age range of 21-30 years. The clinical characteristics showed high leukocytosis with various stage of maturation and a tendency to develop grade 2 normocytic normochromic anemia and thrombo-cytosis was found in the patients.
ASSOCIATION BETWEEN NUTRITIONAL STATUS AND THE OUTCOME OF PEDIATRIC PATIENT WITH DENGUE SHOCK SYNDROME Shidi Laras Pramudito; Dewi Ratna Sari; Ninik Asmaningsih Soemyarso
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (467.693 KB) | DOI: 10.20473/mbiom.v30i1.2020.1-6

Abstract

Background: The association between nutritional status and dengue infection is still considered controversial. Researches that study obesity and shock in pediatric patients with dengue hemorrhagic fever (DHF) has been widely carried out. However, researches that study the association between obesity and the outcome of patients with dengue shock syndrome (DSS) are still rarely done. Objective: The objective was to study the association of obesity in body mass index-for-age (BMI-for-age), gender, and age to the outcome of patients with dengue shock syndrome (recurrent shock or death). Materials and Methods: The research was analytical retrospective observational research with a case-control design using secondary data from the medical records of pediatric patients with DSS in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia during 2015. The analyses used to test the association of obesity (BMI-for-age), gender, age and the outcome of patients with dengue shock syndrome (recurrent shock or death) were the Chi-Square or Fisher Exact test. Results: The sample acquired was 60 data, consisting of 46 patients with DSS without recurrent shock or death and 14 pediatric patients with DSS experiencing recurrent shock or mortality. The frequency of boys and girls were found in equal numbers. Age group >5-10 years was found more common (45%). The results of the analyses test found no association between gender (p=0.542), age (p=0.314), and obesity (p=1.000) and the outcome of pediatric patients with dengue shock syndrome. Conclusion: There were no association found between obesity, age, and gender to the outcomes of pediatric patients with DSS at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Front Matter Vol. 30 No. 1 January 2020 Majalah Biomorfologi
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v30i1.2020.%p

Abstract

Back Matter Vol. 30 No. 1 January 2020 Majalah Biomorfologi
Majalah Biomorfologi Vol. 30 No. 1 (2020): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v30i1.2020.%p

Abstract

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