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Medicra (Journal of Medical Laboratory Science/Technology)
Published by Universitas Muhammadiyah Sidoarjo
ISSN : 25807730     EISSN : 25807730     DOI : https://doi.org/10.21070/medicra
Core Subject : Health,
Health Professions Public Health
Focus : to facilitate scholar, researchers, and lecturers for publishing the original articles of review articles. Scope : Medicra publishes research articles in the field of “medical laboratory (science/technology)” with the following scope: Clinic Chemical Hematology Microbiology Parasitology Immunology Food and beverage analysis Chemical Molecular Diagnostics Toxicology Cytology Histology Epidemiology Laboratory Management Laboratory Quality Control
Arjuna Subject : Profesi Kesehatan - Teknologi Laboratorium Medis
Articles 7 Documents
 1 
Search results for , issue "Vol. 1 No. 2 (2018): December" : 7 Documents clear
Efektivitas Anti Bakteri Perasan Bawang Putih (Allium sativum L.) terhadap Pertumbuhan Staphylococcus aureus: The Effectiveness of Anti-Bacterial Juice of Garlic (Allium sativum L.) on the Growth of Staphylococcus aureus Mardiyah, Siti
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 1 No. 2 (2018): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v1i2.1532

Abstract

Garlic has bioactive compounds that are efficacious as antibacterial (bacteriostatic) in some pathogenic bacteria, which one of them is Staphylococcus aureus. Major antimicrobial component is active on garlic especially allicin. The ability of garlic extract as anti-bacterial because of the combination of alisin and scordinin. Alisin serves as a natural antibiotic capable of killing antibiotic-resistant Staphylococcus aureus. This paper aims to study the effect of concentration of garlic juice on the growth of Staphylococcus aureus and determine the minimum concentration to prevent the growth of the bacteria. This type of research is experimental. The population and sample of this study were culture of pure Staphylococcus aureus grown on MSA medium (Manitol Salt Agar). Total sample of research are 28 samples. Staphylococcus aureus growth data were obtained by indirect observation through laboratory tests. Data analysis techniques used Kruskal-Wallis test with 5% error rate (0,05) and Mann Whitney test through SPSS 17,0 program. The result of anti bacterial test of garlic extract (Allium sativum Linn) with Kruskal-Wallis showed that there was influence of extract concentration of garlic on growth of Staphylococcus aureus (p = 0,000). While Mann - Whitney test results obtained that at 25% concentration is the minimum concentration that effectively prevent the growth of Staphylococcus aureus. Therefore it can be concluded that there is influence of extract of garlic juice on growth of Staphylococcus aureus.
Efektivitas Formulasi Ekstrak Daun Sirih Merah (Piper crocatum) Dengan Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) Terhadap Hiperglikemia Serta Histopatologi Pankreas Mencit: The Effectiveness of Formulation of Red Betel Leaf Extract (Piper crocatum) With Fragrant Pandan Leaf Extract (Pandanus amaryllifolius Roxb.) Against Hyperglycemia and Pancreatic Histopathology of Mice Handini, Hesti Dwi; Rohmah, Jamilatur
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 1 No. 2 (2018): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v1i2.1477

Abstract

Diabetes mellitus (DM) is metabolism diseases characterized by hyperglycemia and change to the cell histophatology structure of pancreas. Red betel leaves (Piper crocatum) and fragnantpandanleaves (Pandanus amaryllifolius Roxb.) has compound metabolic secondary that efficacious as anantidiabetic. The aims of the study were seek the best extract formulations of red betel leaves (EDSM) and extract of fragnantpandan leaves (EDPW) to lowering blood glucose level, repair the damage of islet langerhans, and comparing the effectiveness with metformin. The research was drafted by post test only control group design using male mencit (Mus musculus) for 31 days. In this research used complete random design with 14 treatment groups, they are normal group, DM group, metfomin group, EDPW 100%group, EDSM 10%+ EDPW 90%group, EDSM 20% + EDPW 80%group, EDSM 30% + EDPW 70% group,EDSM 40% + EDPW 60% group,EDSM 50% + EDPW 50%group,EDSM 60% + EDPW 40% group,EDSM 70% + EDPW 30% group, EDSM 80% + EDPW 20% group, EDSM 90% + EDPW 10% group, and EDSM 100%group. Based on in vivo bioassay showed that metformin have a lot of lowering blood glucose levels (p<0,05) than formulation of EDSM and EDPW but not better in improving islet langerhans tissue damage and treatment DM group with EDSM 50% + EDPW 50% effective lowering blood glucose level comparable with metfomin (p>0,05) and better in improving islet langerhans tissue damage caused by alloxan diabetogenic compound.
Efektivitas Temu Kunci (Boesenbergia rotunda) Terhadap Penurunan Kadar Formalin Pada Ikan Tuna (Thunnus sp.): Effectiveness of Key Gathering (Boesenbergia rotunda) Against Reduction of Formalin Levels in Tuna (Thunnus sp.) Zamhariroh, Zamhariroh; Hanum, Galuh Ratmana
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 1 No. 2 (2018): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v1i2.1650

Abstract

Tuna as a marine fish that has an exceptional potential to be the mainstay of Indonesia. The high demand for tuna makes a great opportunity for Indonesia as a producer in the export of these products. Related to this condition, the producers have come up with a variety of ways to keep the fish appear fresh by way of preservation, one of them is by using formalin. Finger root plants have active compounds that can reduce formalin in tuna saponins. This study used tuna fish that had been soaked with a solution containing 10% formalin. The research was conducted at Surabaya City Health Office. Formalin content was measured using the spectrophotometer method. Parameters used were formalin content. The results of this study indicate that the concentration of key solution and storage duration significantly influence at 50% concentration for 5 days is the most effective concentration and duration of immersion with an average yield of 0,04 mg/l.
Hubungan Profil Lipid Dengan Kadar Glukosa Darah Pada Pasien Diabetes Mellitus: Relationship between Lipid Profile and Blood Glucose Levels in Diabetes Mellitus Patients Puspitasari, Puspitasari; Aliviameita, Andika
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 1 No. 2 (2018): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v1i2.1831

Abstract

Diabetes mellitus is disease caused by a disorder of glucose metabolism. At present, diabetes mellitus is health problem in the world. Increased blood glucose levels can increase the risk of complications of various organs, one of which is cardiovascular disease. This study aims to determine the relationship between cholesterol total levels and triglycerides with blood glucose levels in patients with diabetes mellitus. This type of research is observational analytic with cross sectional design. A total of 45 samples were selected selectively at Aisyiyah Siti Fatimah Tulangan Hospital in January 2016-February 2018. The results of multiple linear regression analysis showed a statistically significant relationship between total cholesterol levels and blood glucose (b = 0,607; p = 0,046), and triglyceride levels with blood glucose levels (b = -0,276; p = 0,003). Based on the results, we found a stati
Identifikasi Eschericia coli dan Salmonella sp. pada Air Kolam Renang Candi Pari: Identification of Eschericia coli and Salmonella sp. on the Pari Temple Swimming Pool Water Khakim, Lukmanul; Rini, Chylen Setiyo
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 1 No. 2 (2018): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v1i2.1491

Abstract

Incorrect treatment of swimming pool can contaminate the water with bacteria. Common bacteria in water are Escherichia coli and Salmonella sp, both of which may infect the users of the swimming pool. Infection causes diarrhea and high fever on humans. The aim of this research is to investigate the contamination of Escherichia coli and Salmonella sp at Candi pari swimming pool. Research design used in this research is the development of EMB and SSA selective medium, gram coloring test, and biochemical test to confirm the presence of Escherichia coli and Salmonella sp. Resultsfrom this research is the growth of Escherichia coli and Salmonella sp from 1 ml sample which were inoculated on selective medium. Conclusion from this research is from 2 samples taken from Candi Pari swimming pool, both are positively contaminated with Escherichia coli and Salmonella sp.
Kombinasi Ekstrak Daun Kelor (Moringa oleifera Lamk) Dengan Ekstrak Daun Tin (Ficus carica Linn) Sebagai Larvasida Terhadap Larva Aedes aegypti: Combination of Moringa Leaf Extract (Moringa oleifera Lamk) With Tin Leaf Extract (Ficus carica Linn) As Larvicide Against Aedes aegypti Larvae Hikma, Selani Rahchian; Ardiansyah, Syahrul
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 1 No. 2 (2018): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v1i2.1649

Abstract

The use of synthetic larvicides will be resistance of environmental pollution. The Alternatives for deduct negative impact is Moringa leaves and ficus carica Linn leaves as plant larvacides. The content of Moringa leaves and ficus carica Linn leaves is contain secondary metabolites including saponins, flavonoids, alkaloids, and tannins as larvicides. This research aim knowing toxicity combination Moringa leaf extract and ficus carica Linn leaf extract for Aedes aegypti mosquito larvae. This methode using post test only control group design, with five variations of the concentration Moringa leaf extract combination is 100%: 0% tin leaf extract; 25%: 75%; 50%: 50%; 75%: 25%; and 0%: 100% with 4 repetition. The data analysis by univariate and bivariate (kruskal wallis) and mann whitney tests for differences in two samples.m The best result of research is concentration 75%:25% consist death larva time to 10 with total larvae 62%, 25%:75% with total larvae 19%, and increasing for 50%:50% with total larvae 34%.
Penentuan Kadar Logam Berat Merkuri (Hg) Dan Cadmium (Cd) Dalam Kosmetik Dengan Atomic Absorption Spectroscopy (AAS): Determination of Heavy Metals Mercury (Hg) And Cadmium (Cd) In Cosmetics With Atomic Absorption Spectroscopy (AAS) Wulandari, Deyana Dyah; Andini, Ary; Puspitasari, Adela
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 1 No. 2 (2018): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v1i2.1830

Abstract

Cosmetics are materials intended for use on the outside of the human body or teeth and mucous membranes of the mouth especially to cleanse, scent, change the appearance and / or improve body odor or protect or nourish the body in good condition. In cosmetics can contain harmful active ingredients, one of them is heavy metal. In this study we tested the heavy metals content of mercury and cadmium on cosmetic samples sold in the online market using Atomic Absorption Spectroscopy (AAS) with wavelengths of 253,7 nm for mercury and 228,8 nm for cadmium. Result showed that from 10 cosmetic samples, there were no cosmetic products containing heavy metals mercury and cadmium above the predetermined maximum limit.

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