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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Kimia Riset Jurnal Ilmiah Kedokteran Wijaya Kusuma THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Jurnal Ilmiah Soulmath : Jurnal Edukasi Pendidikan Matematika Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Medical Technology and Public Health Journal Sains dan Matematika Medicra (Journal of Medical Laboratory Science/Technology) Jurnal Abdimas Berdaya : Jurnal Pembelajaran, Pemberdayaan dan Pengabdian Masyarakat Jurnal Abdimas Kartika Wijayakusuma Indonesian Journal of Innovation Studies Procedia of Social Sciences and Humanities Oshada Jurnal Teknologi Laboratorium Medik Borneo Manajemen Pelayanan Kesehatan Indonesian Journal Health Science and Medicine Jurnal Analis Kesehatan Kendari

Chylen Setiyo Rini

Universitas Muhammadiyah Sidoarjo

Author-ID : 3649951

Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Veterinary Other

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ANALISIS TINGKAT KEPUASAN PUBLIK TERHADAP PELAYANAN RUMAH SAKIT BERDASARKAN METODE FUZZY TOPSIS MCDM Azizah, Nuril Lutvi; Prasojo, Bayu Hari; Rini, Chylen Setiyo
Jurnal Ilmiah Soulmath : Jurnal Edukasi Pendidikan Matematika Vol 7 No 1 (2019)
Publisher : Universitas Dr. Soetomo

One of the National Development efforts in the health sector is the availability of adequate and quality health services. These qualities can be seen from several indicators, one of which is the level of patient satisfaction in providing health services. This study aims to provide an evaluation of public satisfaction with hospital services with a case study of several private hospitals in Sidoarjo Regency, so that it can be used as an evaluation or input in assessing hospital internal quality standards based on predetermined selection criteria. The method to be used is Fuzzy Multi-Criteria Decision Making (FMCDM) and TOPSIS which is used to conduct numerical, logic, and analytical scales. From the results of fuzzy analysis of the average 5 aspects, namely tangible, Reliability, responsiveness, assurance, and empathy is 13,29 for RSI Siti Hajar Sidoarjo with an average weight of 0.2 and the quality is still at the level of 5.3 and the fuzzy at Delta Surya Hospital Sidoarjo is 11.74 with an average weight of 0.2 and the quality is still at the level of 4.67 which means both hospitals it is still in the category standard and the relationship in service still needs improvement.

KAJIAN POTENSI USAHA PEMBUATAN TERASI BUBUK DESA TAMBAK OSO KECAMATAN WARU SIDOARJO Chylen setiyo rini; Yanik Purwanti
Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Vol 1, No 2 (2018): Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstormin
Publisher : Politeknik Harapan Bersama

AbstrakDesa Tambak Oso memiliki potensi komoditas unggulan dan nilai ekonomis yang tinggi dari hasil olahan bandeng dan udang. Salah satu kelompok usaha yaitu pengelolaan terasi secara tradisional. Berdasarkan potensi tersebut jika teknologi pengolahan khususnya pengolahan terasi yang dikemas dalam bentuk bubuk diterapkan oleh masyarakat Desa Tambak Oso kemudian bisa dijadikan industri usaha kecil maka dapat menjadi sumber mata pencaharian baru sehingga ekonomi dan gizi masyarakat dapat meningkat. Oleh sebab itu penerapan ilmu pengetahuan dan teknologi (IPTEK) tentang teknologi pengolahan terasi bubuk sangat penting untuk dilaksanakan karena mudah diaplikasikan di masyarakat, potensi wilayah yang mendukung dan teknologinya tepat guna. Kegiatan ini bertujuan untuk memotivasi masyarakat untuk mengembangkan kreativitas dalam mengembangkan potensi alam yang ada. Hasil dari pengabdian ini semula masyarakat belum mengerti membaca peluang usaha yang ada setelah mendapat penyuluhan masyarakat antusias mengembangkan sumberdaya yang ada di desa menjadi produk yang bernilai ekonomi tinggi. Kata kunci—Desa Tambak Oso, Teknologi pengolahan terasi bubuk

Antioxidant activity assay of white Turi (Sesbania grandiflora (L.) Pers.) extracts using DPPH radical scavenging method Jamilatur Rohmah; Ida Agustini Saidi; Chylen Setiyo Rini; Zulfida Ainindiyah Putri Purwanto; Karlia Hedit Tiana; Tri Chahyani Rahmawati Putri
Pharmaciana Vol 10, No 3 (2020): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Turi (Sesbania grandiflora (L.) Pers.) is a type of plant belonging to the Fabaceae family that is widespread in Indonesian territory and has the potential as a natural free radical scavenger. The study aims to compare the antioxidant activity from white Turi (Sesbania grandiflora (L.) Pers.) leaf extracts in various extraction solvents. The determination of antioxidant activity was carried out using the DPPH method with a UV-Vis spectrophotometer. The turi plants used were originated from Mojosari, Mojokerto, East Java, Indonesia. Simplicia turi leaves were macerated in various extraction solvents: ethanol, ethyl acetate, and n-hexane for 24 hours. The extraction results are then subjected to phytochemical and antioxidant activity tests. The obtained result shows that the white turi extract has antioxidant activity with strong activity against DPPH radicals; with n-hexane > ethyl acetate extract > ethanol extract. The IC50 values of ethanol, n-hexane, and ethyl acetate extracts of white turi leaves were 33.09 ppm; 26.99 ppm; and 25.33 ppm. Based on these results, the white turi plant (leaves) can be one of the natural sources of antioxidants to prevent diseases caused by free radicals.

AKTIVITAS SITOTOKSIK EKSTRAK SELADA MERAH (Lactuca sativa var. Crispa) PADA BERBAGAI PELARUT EKSTRAKSI Jamilatur Rohmah; Chylen Setiyo Rini; Fitria Eka Wulandari
Jurnal Kimia Riset Vol. 4 No. 1 (2019): Juni
Publisher : Universitas Airlangga

Penelitian ini bertujuan untuk mengetahui kandungan metabolit sekunder dan aktivitas sitotoksik dengan nilai LC50dari ekstrak selada merah (Lactuca sativa var.Crispa) pada berbagai pelarut. Sampel selada merah yang digunakan didapatkan dari desa Turirejo kecamatan Lawang-Malang. Simplisia selada merah di ekstraksi dengan metode maserasi menggunakan variasi pelarut yaitu pelarut etanol, metanol, etil asetat, dan n-heksana selama 24 jam. Hasil maserasi dipekatkan dengan alat rotary vacuum evaporator. Kemudian dilakukan uji skrining fitokimia serta KLT untuk mengetahui kandungan metabolit sekunder dalam sampel. Pengujian aktivitas sitotoksik dilakukan dengan metode BSLT (Brine Shrimp Lethality Test). Hasil ekstraksi didapatkan ekstrak kental etanol, metanol, etil asetat, dan n-heksana secara berturut-turut sebesar 17,30 g; 12,32 g; 25,61 g; dan 3,76 g. Dan hasil dari uji fitokimia menunjukkan ekstrak etanol selada merah mengandung flavonoid, tanin, saponin, triterpenoid, steroid dan alkaloid. Sedangkan ekstrak metanol selada merah mengandung alkaloid, saponin, dan tanin. Pada ekstrak etil asetat selada merah mengandung alkalid, saponin, steroid, dan tanin. Dan pada ekstrak n-heksana selada merah mengandung alkaloid, steroid, triterpenoid, dan tanin. Hasil aktivitas sitotoksik ekstrak metanol memiliki bioaktivitas tertinggi terhadap Artemia salina Leach. dibandingkan dengan ekstrak etanol, etil asetat, dan n-heksana. Nilai LC50ekstrak etanol, metanol, etil asetat, dan n-heksana secara berturut-turut adalah 322,288 ppm; 68,632 ppm; 1934,287 ppm; dan 170,115 ppm.Kata kunci: Selada merah (Lactuca sativa var. Crispa), sitotoksik, Artemia salina Leach, BSLT.

AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL, ETIL ASETAT, DAN n-HEKSANA BATANG TURI PUTIH (Sesbania grandiflora (L.) Pers.) DENGAN METODE DPPH (1,1-Diphenyl-2-picrylhydrazyl) Jamilatur Rohmah; Ida Agustini Saidi; Chylen Setiyo Rini; Devi Arvindani Masyitha
Jurnal Kimia Riset Vol. 5 No. 1 (2020): Juni
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkr.v5i1.20900

Turi (Sesbania grandiflora (L.) Pers.) merupakan jenis tanaman yang tersebar luas di wilayah Indonesia dan termasuk dalam famili Fabaceae serta memiliki potensi sebagai antioksidan alami. Tujuan dari penelitian ini yaitu untuk mengetahui aktivitas antioksidan ekstrak etanol, etil asetat, dan n-heksana dari batang turi putih (Sesbania grandiflora (L.) Pers.). Penentuan aktivitas antioksidan dilakukan dengan metode DPPH menggunakan alat spektrofotometer UV-Vis. Tanaman turi yang digunakan berasal dari Mojosari, Mojokerto. Simplisia daun turi dimaserasi pada berbagai pelarut etanol, etil asetat, dan n-heksana selama 24 jam. Hasil ekstraksi kemudian dilakukan uji fitokimia, KLT dan aktivitas antioksidan. Hasil penelitian yang diperoleh menunjukkan bahwa ekstrak etanol, etil asetat, dan n-heksana batang turi putih (Sesbania grandiflora (L.) Pers.) memiliki aktivitas antioksidan (IC50) yang termasuk ke dalam aktivitas antioksidan yang kuat terhadap radikal DPPH dengan nilai IC50 masing-masing ekstrak yaitu ekstrak etanol sebesar 24,30 ppm, ekstrak etil asetat sebesar 26,98 ppm, dan n-heksana sebesar 25,33 ppm. Sehingga tanaman turi putih (daun) dapat menjadi salah satu sumber zat bioaktif antioksidan alami untuk mencegah terjadinya penyakit yang disebabkan oleh radikal bebas.

The Detection of TB Lungs with Microscopic and the Rapid Molecular Test Methods Fifi Isti Tamtyas; Chylen Setiyo Rini
Medicra (Journal of Medical Laboratory Science/Technology) Vol 3 No 1 (2020): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v3i1.650

Mycobacterium tuberculosis is a cause of tuberculosis (TB ) disease. In this research Mycobacterium tuberculosis can be detected using the Microscopic and Real-Time PCR. This research aims are to know the difference in the results of the examination Mycobacterium tuberculosis with microscopic method and Real-Time PCR. This research used an experimental research design and was tested using the Chi Square test. This results showed at significant difference (p=0.000) detection of pulmonary TB disease by microscopic and Real-Time PCR methods

Date Palm (Phoenix dactylifera L.) Flour as an Alternative Culture Media for the Growth of Escherichia coli and Bacillus cereus Chylen Setiyo Rini; Ida Agustini Saidi; Jamilatur Rohmah
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 12, No 1 (2023): March 2023
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v12i1.2487

The high cost of bacterial growth culture media can result in obstacles in the process of practicum or research in the field of microbiology. Date palm (Phoenix dactylifera L.) is the oldest fruit plant that grows in the Arabian Peninsula, North Africa and the Middle East. Dates are a source of high energy food with sugar content of 72% - 88%. This research was conducted to test the ability of date palm flour to grow Escherichia coli and Bacillus cereus bacteria as an alternative medium to replace NA media. In this study using total number of bacteria/ TPC (Total Plate Count) method to calculated the number of colonies of bacteria. The results of this study the number of colonies of Escherichia coli bacteria was more than the number of colonies of Bacillus cereus, that is 54 x 105CFU/g on concentration media 8 gr. When compared with NA media, date palm flour media can be used as an inexpensive alternative culture medium for bacteria.

Uji Daya Hambat Ekstrak Segar Buah Pare (Momordica charantia Linn.) Terhadap Pertumbuhan Bakteri Klebsiella pneumoniae Dan Streptococcus pneumoniae chylen setiyo rini
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Vol 6 No 1 (2023): The Journal Of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmlt.v6i1.14494

Saluran pernapasan merupakan organ tubuh manusia yang banyak mengandung populasi bakteri (sekitar 13 spesies) yang dapat menjadi patogen seperti Klebsiella pneumoniae dan Streptococcus pneumoniae. Oleh karena itu, perlu adanya upaya mengendalikan Klebsiella pneumoniae dan Streptococcus pneumoniae dengan bahan dari bahan alam, salah satunya yaitu pare (Momordica charantia Linn). Buah pare (Momordica charantia Linn) telah terbukti khasiatnya sebagai obat yang memiliki kandungan senyawa seperti alkaloid, saponin, fenolik, streoid, flavonoid, dan tanin yang memiliki kemampuan sebagai antibakteri. Jenis penelitian ini adalah penelitian eksperimental. Dengan metode difusi kertas cakram atau Kirby-Bauer dengan 5 konsentrasi yaitu : 20%, 40%, 60%, 80%, 100%, dan digunakan antibiotik kloramfenikol sebagai (kontrol+). Pengujian dilakukan sebanyak 3 kali pengulangan. Data yang peroleh kemudian diuji menggunakan uji Anova one way dengan nilai signifikansi 0,05. Hasil penelitian menunjukkan bahwa ekstrak segar buah pare efektif terhadap pertumbuhan bakteri Klebsiella pneumoniae dan Streptococcus pneumoniae. Konsentrasi optimum pada bakteri Klebsiella pneumoniae diperoleh pada konsentrasi 100% dengan diameter sebesar 21,31 mm dan konsentrasi 80% dengan diameter sebesar 22,36 mm pada bakteri Streptococcus pneumoniae, sedangkan hasil uji ANOVA one way yang telah dilakukan terhadap diameter zona hambat bakteri Klebsiella pneumoniae dan Streptococcus pneumoniae diperoleh nilai signifikan p=0,000 dari hasil tersebut diketahui bahwa nilai <0,05 yang menunjukkan ada pengaruh yang nyata dari pemberian ekstrak segar buah pare terhadap pertumbuhan bakteri Klebsiella pneumoniae dan Streptococcus pneumoniae.

Effect of Papaya flower ethanolic extract (Carica Papaya) on the time kill of tetracyclin against Escherichia Coli Anugraheni Anugraheni; Chylen Setiyo Rini
Pharmaciana Vol 13, No 2 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v13i2.24711

Papaya (Carica papaya) is found throughout Indonesia. Papaya flowers contain saponin, tannin, alkaloid, and flavonoid compounds which functions as antibacterial. Escherichia coli is a Gram-negative rod bacteria that could be found in the human large intestine as a cause of diarrhea. The study aimed to determine the effect of papaya flower extract and a combination of papaya flower extract with tetracycline antibiotics using the smallest concentration capable of inhibiting 50% of bacterial growth against Escherichia coli bacteria ATCC 25922 using the time-kill test method. This study was the method of Minimum Inhibitory Concentration (MIC) and time-kill. The MIC of the ethanol extract of papaya flower was 2 mg/mL. The time-kill test showed that the death phase was occurred at 4 - 24 hours. The bacteriostatic effect of the extract was obtained at 0 hours to 24 hours, while the antibiotic and its combination with the extracts had a bactericidal effect at 8 hours and 24 hours.

The Potential of Mango (Mangifera infica L.) Peel of Apple Varieties By Infusion And Maceration In Inhibiting Pseudomonas aeruginosa And Propionibacterium acnes: Potensi Kulit Mangga (Mangifera infica L.) Varietas Apel Secara Infusa Dan Maserasi Dalam Menghambat Bakteri Pseudomonas aeruginosa dan Propionibacterium acnes Rahmawati, Vifin Putri; Rini, Chylen Setiyo
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.904

Plants have many chemical components. The use of natural ingredients as an alternative treatment in dealing with diseases, especially acne. One of them is mango (Mangifera indica L.) varieties of apples obtained at the Larangan Main Market in Sidoarjo. This study aims to determine the potential of infusion and maceration of mango skin varieties in inhibiting Pseudomonas aeruginosa and Propionibactrium acne at various concentrations. This antibacterial potential test was carried out using the diffusion method of the wells. The antibacterial potential is characterized by the formation of a clear zone around the well called the inhibition zone. This study uses 10 concentrations namely 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90% and 100% and Clindamycin as positive control and aquades as negative control. Based on the results of the Two Way ANOVA test data obtained were not normally distributed, therefore a comparison test was performed using the Kruskal-Wallis test with a sign value (α <0.05). This showed that there were significant differences in the use of various concentrations. The maceration extract concentration of 100% is the best concentration to form a zone of inhibition against P. aeruginosa of 17.9 mm and P. acne bacteria of 13.2 mm. The results of the infusion extract concentration did not form inhibitory zones in both of P. aeruginosa and P. acnes.

Co-Authors AA Sudharmawan, AA Absari, Eki Puji Ade Teti Vani Aini, Aqiliyanti Nur Aisyah Putri, Aprilia Akbar, Aulia Rizky Fadhillah al-akbar, Wildan Alhafiz, Rafaiz Filaili Ambarani, Putri Yuli Anggraeni, Rifka Wahyu Anugraheni Anugraheni Azzahra, Aulia Bayu Hari Prasojo Devi Arvindani Masyitha Fifi Isti Tamtyas Fitria Ayu Prayekti, Rahmatika Fitria Eka Wulandari Galuh Ratmana Hanum Hartin, Ellyce Huesein, Ida Agustini Saidi Imamah, Siti Aliyatul Jamilatur Rohmah Jamilatur Rohmah Juliana, Tiara Karlia Hedit Tiana Kimberly, Bella Tasya Liany, Ayundah Novie Lidyaningrum, Galuh Ajeng Lindawati, Sari Liyaajul, Pratasyah Makhnunah, Makhnunah Miftahul Mushlih MUFIDAH, LAILATUL Mustar Nisak, Khairun Nugroho, Rhenald Aditya NUR EFENDI Nuril Lutvi Azizah Oktaruliawan, Veronika Ony Wibriyono Angkejaya Puspitasari Puspitasari Puspitasari Puspitasari Puspitasari Putri, Wafiq Zahro Rahmawati, Vifin Putri Saputra, Eduwardo Roy Sari, Azizah Krismonita Setyaputri, Nabila Hani SITI CHOLIFAH Sofi Rahayu, Bella Sukmawati Sukmawati Tis’iyyah , Siti Nur Maghfiroh Tri Chahyani Rahmawati Putri Wahyudi, Eko Bambang Widyaningrum, Leni Yuroh Yanik Purwanti Yeninastiti, Reny Zulfida Ainindiyah Putri Purwanto

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