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Indian Journal of Forensic Medicine & Toxicology
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Core Subject : Health,
Articles 5,497 Documents
Effect of SafMannan on Local Iraqi Laying Hens Performance Yasser J. Jameel1 , Mohannad M. Alrekabi2 , and Nihad A. Ali3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11628

Abstract

Phase one laying hens diet were included of two levels of yeast cell wall (YCW) called SafMannan fromPhlio-USA company. A total of 81 Iraqi laying hens 14 weeks’ old were distributed into three treatments.Each treatment has 27 hens were distributed into 27 individual cages (one hen per cage). First group henswere fed on basal diet without supplement (CON). Chicks in second and third group were fed on 250 ppm(Saf 250) and 500 ppm (Saf 500) SafMannan respectively. Body weight were weighted weekly from 14-34weeks; while, egg weight was numbered weekly from 20-34 weeks. Results revealed that body weight wereenhanced significantly (p?0.05) in (Saf 250) and (Saf 500) respectively as compared with the control group(CON). The highest egg weight was found in the group was received (Saf 250). Egg weight were increasesignificantly (p?0.05) in groups were received SafMannan (Saf 250) and (Saf 500) respectively as comparedwith the (CON). In conclusion, adding of SafMannan as a prebiotic in the poultry hens diet at 250 ppm wereenhanced the egg weight and body weight of local Iraqi laying hens.
In vitro measurement volume of the neonate thyroid gland Atyaf Mohammed Ali1 , Anas Hamed Musleh1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11630

Abstract

Measurement and replacement fluid methods to estimate the thyroid gland volume. Because there is wideranging of variation in the volume of the thyroid gland in healthy individuals of different geographicallocation, ages, gender, and races.Objectives: To estimate normal neonate thyroid gland volume it can throwlight to help clinicians deal better with the gland during neonatal age besides providing native standarddata. Period: From Sept 13, 2018, to Mar 22, 2019. Material & Methods: Total of 48 subjects wereincluded, 24 male and 24 female. The neonate thyroid gland collected and inspected grossly and taken allmeasurements, then use these measurements for finding volume thyroid gland. Also, the volumeis taken byusing replacement fluid. Results: The mean aggregate thyroid gland volume of measures method for malesubjectsstudy was 250.53 ± 4.37mm3, while a female was 246.31 ± 3.42 mm3. The mean volume thyroidgland of replacement fluid method for male subjects study was 295.71 ± 4.41mm3, while the female was291.43 ± 4.04. The mean thyroid volume of the male is expressively larger than female in both methods butstatically non-significant variation. The difference between both ways statistically highly significant (p<0.01). Conclusion: according to results that achieved by two methods, we should use another correctionfactor, higher than 0.749, until getting the nearest value to replacement fluid. Working out different ages toestablish average data.
Deleted Azzah Bahaa Abdulazeez 1,2, Ismail Hussein Aziz 1 , Mohammed Mashni Farhan 2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11631

Abstract

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Effect of Alpha Lipoic Acid on Polycystic Ovary Syndrome with Insulin Resistance
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11632

Abstract

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductiveage women where insulin resistance plays an important role. Insulin resistance makes the first line treatment,clomiphene citrate (CC) treatment, become ineffective. Alpha Lipoic Acid (ALA) is believed to be analternative treatment for CC-resistant PCOS. Objectives: The aim of the study is to understand the effectof ALA in Insuline receptor substrate 1 (IRS-1) expression, Glucosa transporter 4 (GLUT-4) expression,and folliculogenesis in insulin resistant PCOS rat model. Methods: This was an experimental study withrandomized posttest only control group design. 30 females rat injected with testosterone propionate (TP)1mg/100gram bodyweight for 28 days then divided into 3 groups. Negative control group receive no othertreatment, positive control group receive a placebo for 14 days, and treatment group receive ALA for 14 days.IRS-1 and GLUT-4 expression is evaluated with immunohistochemistry, while folliculogenesis is evaluatedby counting the number of follicle in each stage. Results: Mean IRS-1 expression in muscle in treatmentgroup is significantly higher than other groups (4.28±1.05; 3.02±1.03; 1.86±0.83, p <0.01 respectively).Mean GLUT-4 expression in treatment group is significantly higher than other groups (4.28±0.91; 3.20±1.14;1.40±0.55, p <0.01 respectively). Mean number of follicle in each stage in treatment group are significantlyreduced than other groups (all p <0.05). Conclusion: ALA increase the expression of IRS-1 and GLUT-4,and also reduce the number of follicle in each stage of folliculogenesis.
Assessment of Women’s Knowledge Concerning Hydatidiform Mole at Maternity Hospitals in Baghdad City Fatima Fadel Benyian
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11633

Abstract

Hydatidiform mole results from abnormal fertilization. It is the most common disorder of gestationaltrophoblastic diseases can be partial or complete. Early detection of molar pregnancy and monitoring canreduce complication particularly coriocarcinoma. The fetus typically dies, and a miscarriage often occurs.Objectives: To assess women’s knowledge concerning Hydatitiform mole and find out the associationbetween women’s knowledge with their study variables.Methods: Descriptive study was conducted from November 2019 to February 2020 at maternity hospitalsin Baghdad city. Non probability (purposive sample) was used to collect the data from (100) women whoattending outpatient clinics at maternity hospitals. A questionnaire was constructed about knowledgeassessment tool were designed and prepared by the researcher. A pilot-test is conducted in order to determinethe reliability of the questionnaire in a sample of (20) women who were excluded from the study sample.Data was analyzed through the use of SPSS version 20.Results: The main results revealed that the highest percentage (41.6%) of women’s age was (20-29) years.More than half of them (60 %) are graduated from Secondary Nursing School. They have inadequateknowledge. There are no statistical significant differences between level of knowledge and women’s age oreducational level.Conclusion: This study shows that the knowledge of study sample concerning Hydatitiform mole wasinadequate.Recommendations: It is important to design a booklet or pamphlet about Hydatitiform mole risk factors,signs and symptoms, screening, to reach for all women over the country in order to early detection andprevention.
Adherence and Satisfaction of Deferasiroxversus Deferoxamine in Transfusion-Dependent Beta-Thalassemia Mustafa Al-Khyate1 , Zeina A.Althanoon2 , Nasih A.Alkazaz3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11634

Abstract

Objectives: The present study was aimed to compare the adherence and satisfaction with deferoxamine(Desferal®) versus deferasirox (Exjade®), a novel oral iron chelator, in patients with transfusion-dependentbeta-thalassemia.Patients and Methods: In this cross?sectional, single-center study, 108 homozygous ?thalassemia majorpatients aged between 3-21 years old were enrolled. They were on regular blood transfusions and ironchelators (either deferoxamine or deferasirox) for about three months. Another fifty-six apparently healthynon-thalassemic subjects were enrolled as a control group. Results: Adherence and satisfaction wereassessedbyusing a simplequestionnaire establishedduring an interviewwithpatientsortheirparents.The serumferritinlevel was measuredbythe ELISAmethod.Our findings showed that adherence and satisfaction in the deferasirox group were more than that withdeferoxamine group patients. Serum ferritin level in the deferasirox group was significantly lower than inthe deferoxamine group at (p?0.001). while the control group was significantly lower than both patientsgroups at (p?0.001). Patients on deferasirox had lower adverse effects than the deferoxamine group sincedeferoxamine produce irritation and pain at the injection site for the patients.Conclusion: Our findings concluded that deferasirox is an effective iron chelator as deferoxamine but withbetter adherence and satisfaction than deferoxamine. Deferasirox can be used as a preferred iron chelatortherapy in iron-overload patients with beta-thalassemia.
Clinical Treatment of UTI in Rats Induced by Pathogenic E. Coli Wissam Qadry Mutaab Alqaissy1 , Thaar Mohammed Najim2 , Bahjat Fakhri Mahmood Al-shammari1 , Mustafa
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11635

Abstract

The present study objective was to evaluate the therapeutics effects of ciprofloxacin and gentamicin on UTIinduced experimentally by E. coli in rats. Forty female rats were divided into two groups, infected (30 rats)and control (10 rats). The infected group were inoculated intraurethral by 108suspension of E. coli. Then theinfected group subdivided into 3 subgroups, G1 which serve as control positive, G2 which inoculated by E.coli and then treated by ciprofloxacin 50mg/kg, G3 were inoculated by E. coli then treated with gentamicin40 mg/kg.Treatment with antibiotics started 24 hours after bacterial inoculation and finished 72 hours afterthe initial therapy. The length of antibiotic medication was chosen for both antibiotics as a short-term 3 daystherapy.The animals were monitored for presence of signs. E. coli urine bacterial demonstration were doneat 1 week before infection and 24hrs., 48hrs, 96hrs, 6 days, 12 days and 24 days after infection. There wassignificant increase (P<0.05) in E. coli viable count in all infectedgroups, in addition the result of opticaldensity (OD) by using spectrophotometry record increased threshold of the OD of the urine culture of allinfected groups after (24 hrs.) of infection compared with control group, The current results showed thatUTI symptoms and bacterial isolation were decreased after treatment by both ciprofloxacin and gentamicinas compared with G1 group.In conclusion, ciprofloxacin and gentamicin can alleviate the symptoms of UTI after single dose.
Artemesiaannua L. Silver Nanoparticles Exhibit Anticancer Activity by ROS mediated apoptosis in MDA-MB-231 Cells Renugadevi Karthikeyan1 , Julius Amaldas2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11636

Abstract

Aim of this study was to investigate the growth inhibitory effect of Artemesisannua L. silver nanoparticles(A.annuaAgNPS) on human triple negative breast cancer tumor cell line MDA-MB-231. Cells werecultured and treated with A.annua water extract and A.annuaAgNPS to determine the half inhibitoryconcentration (IC50). Oxidative stress was determined using lipid peroxidation (LPO), ROS generation andby determining the levels of antioxidants, superoxide dismutase (SOD) and reduced glutathione (GSH).Further, the mechanism of apoptotic induction was assessed by DNA fragmentation analyses. We observedthat A.annuaAgNPS significantly caused growth inhibition by increasing levels of LPO and ROS, in a dosedependent manner with reduced level of endogenous antioxidant enzymes. Increased shear in genomic DNAfrom MDA MB231 cells treated with A.annuaAgNPS shows apoptosis to be the cause of cell cell death. Weconclude that A.annuaAgNPS can be useed as a therapeutic agent against breast cancer.
Implant Screw Breakage: A Review Article Vijay Ebenezer
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11638

Abstract

Dental implants have revolutionized the treatment for edentulous and partially edentulous patients, andsuccessful implant integration has been well documented for patients with those clinical conditions. Withthe high rate of implant success for edentulous individuals, the concept of osseointegrationhas become apredictable treatment modality[2]. Yet this cutting-edge treatment modality is not without its own set ofadversities. Implant failures are as common as implant success. The types of implant failures are 1) loss ofintegration, 2) positional failures 3) soft tissue defects, and 4) biomechanical failures. In this article we cometo the conclusion that the mechanical stability of the implant is a multi-factorial aspect.
Fate of Immediate Implants Vs Single Tooth Implants: A Review Article Balakrishnan1 , Vijay Ebenezer2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11644

Abstract

Dental Implants have over the decades become one of the most versatile treatment techniques with goodsurvivability rates. They have come a long way and have advanced further and further, improving all qualities.A more recent technique of implant placement is Immediate Loading Implants. Yet it has not yet become thego to technique for day to day treatment of edentulous cases as it has a significant chance of failure.Methodology: Pubmed database was searched for the keywords “IMMEDIATE IMPLANTS”, “DELAYEDIMPLANTS”, “FATE OF IMPLANTS” 158 articles were found.Out of the 158 articles, the non dental articles were excluded to get 38 articles.The duplicates were excluded to get 4 articlesThese 4 articles were then reviewd and data for this Review Article was obtained.