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Indian Journal of Forensic Medicine & Toxicology
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Core Subject : Health,
Articles 5,497 Documents
Association of the Depth of Invasion wth Lymph Node Metastasis in Oral Squamous Cell Carcinoma Patients - A Retrospective Study Aklesha Behera1 , Hannah.R2 , Abilasha Ramasubramanian3 , Pratibha Ramani4 ,
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12542

Abstract

Oral squamous cell carcinoma is the most common oral malignancy representing upto 80 % to 90% ofall malignancies of oral cavity. In Indian population, it ranks 3rd of all carcinomas. Dietary factors andexternal factors like tobacco, smoking and alcohol consumption are the major causes for progression of oralsquamous cell carcinoma. Histopathologically, the tumor progression is assessed by TNM staging. It is themost common and widely practised histomorphological evaluation of tumor progression. Depth of invasionis also another tool for evaluating tumor progression in OSCC and is also used widely in every clinicohistopathological slide evaluation and diagnosis. In this study, a correlation was made between depth ofinvasion and nodal metastasis. All the data was collected after checking 86,000 patient records. Details suchas age, sex, pathological TNM staging, depth of invasion and cases with nodal metastasis were tabulated.Association was made using the IBM SPSS version 20.0. Pearson chi square test did not show any significantassociation between depth of invasion with nodal metastasis. Other factors like pattern of invasion, tumordifferentiation, site of the lesion as well as the age of the patient has to be taken into consideration for futureassessment.
Correlation Between Highly Sensitive C-Reactive Protein Level in Cases of Preeclampsia with or without Intrauterine-Growth Restriction Alaa Mohammed Sadiq1 , Canary Muhamed Hussein2 , MaithmGhaly Yousif 3 and RausamJassim Mohammed4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12543

Abstract

Background: Preeclampsia is one of hypertensive disorder that affects 4% of pregnant women, the exactcause cannot be identified and it is one of the major causes of both maternal and fetal morbidity and mortality, also it puts a burden on perinatal outcome as prematurity and Intrauterine growth restriction.Continuoussearch for predictive markers of severe PE is important and can be used to target high risk women foreffective preventive treatment. Aim of study: to evaluate Highly Sensitive C-Reactive Protein role usedas predictive factor for severity of preeclampsia and whether it can be used to predict development ofIntrauterine growth restriction. Patients and methods: this is a cross-sectional study includes 80 pregnantwomen with their age 18-35 years , their gestational age range between 32- 40 weeks , admitted to ALZahraa teaching hospital in Najaf, whose diagnosed as PE based on blood pressure measurement andproteinuria. Full history and clinical examination were performed, venous blood aspirated for each womenfor biochemical analysis, Liver functions tests, Renal function tests, Highly Sensitive C- Reactive Protein,and Doppler ultrasound. Results:The patients divided into those with mild PE and severe PE, with orwithout IUGR. No significant difference between the level of Highly Sensitive C-Reactive Protein and theseverity of PE as p value was[0.779], but there is significant difference between the presence of IUGR andthe level of Highly Sensitive C-Reactive Protein when it is? 2mg/L as the p value was[0.020]. Conclusion:We conclude that Highly Sensitive C-Reactive Protein is not significantly associated with the severity ofPreeclampsia but associated with intra uterine growth restriction
Renal Function Tests in Women with Preeclampsia with and without Intrauterine Growth Restriction Alaa M. Sadeq¹, Fawz A. Mohammed2 , Canary Muhammed Hussein3 , Maitham G. Yousif4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12544

Abstract

Background: The kidney is the most likely to be affected by endothelial injury in patients with preeclampsia,so assessment of renal function is essential in the evaluation of the pregnant women with preeclampsia. Aimof the study: to evaluate which test of renal function in preeclamptic patients with and without intrauterinegrowth restriction is more useful. Patients and method:150 women in third trimester with preeclampsiaover period of 14 months diagnosed based on measurement of blood pressure and presence of proteinuriadivided into two group : group A those preeclamptic women without feature of intrauterine growth restrictionby ultrasound and Doppler study and group B those with features of intrauterine growth restriction. Bloodaspirated from each woman and blood urea, serum creatinine, serum uric acid, and serum cystatin-C weremeasured using spectrophotometer. Results: From 150 women with preeclampsia 120 of them had nofeatures of intrauterine growth restriction and 30 had some features. Mean maternal age of patients includedwas 22±0.3 in group A and 24±0.7 in group B which is not differ statistically while the body mass indexshould statistically differences between the two group with P value <0.001. the blood urea, serum creatinineand serum uric acid levels found to be higher in group B but not reach statistical differences while serumcystatin C are higher in group B mean 1.23±0.45when compared to group A 1.08±0.97with p value <0.001.Conclusion:Renal function may be affected more in patients with intrauterine growth restriction and cystatinC level is more promising marker for renal function in preeeclamptic women.
5-Years Prevalence Study of HBV and HCV infections in Babylon Province: Forensic Helping Data Kadhim Jawad Mohammed1 , Hussein O.M. Al-Dahmoshi2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12545

Abstract

HBV and HCV infections are serious global health care problem because they may end with chronichepatitis, cirrhosis, and hepatocellular carcinoma. HBV infection results in approximately 2 billion humaninfections while HCV approximately 160 million individuals. Raw database were collected from Generalhealth department at Babylon Health directorate for 715505 investigated person during a period from Jan.2015 to Dec. 2019. Blood samples was drawn in Gel tube from suspects and centrifuged to separate theserum. Serum submitted for investigation of HbsAg and HCV Ab by both rapid immunochromatographictest and ELISA test. Actually the database taken from Babylon Health directorate and the results analysisdepends upon dividing of data records from four health sectors, blood bank record lab, health care checkinglab, pre-surgery checking, Marriage lab, thalassemia lab, Hemodialysis lab Prisoner and foreigners lab. Theresults revealed that , total positive cases were 4284 and 2260 for “HBV and HCV” respectively. The highestno. of cases for both “HBV and HCV” were recorded in 2018 (976 and 467) and (961 and 557) for “HBVand HCV” respectively. The incidence rate of “HBV and HCV” were varies worldwide. The results revealedthat the occurrence rate (Mean ± SD) of “HBV” was (0.627±0.134) while for HCV was (0.327±0.084). Theresults revealed that, there is no defined month or semester for high rate infections. The high prevalencepercentage were showed for prisoner-foreigner category (48.53 and 45.95 for HBV and HCV respectively)followed by surgery (22.66 and 19.03 for HBV and HCV respectively), blood bank (14.03 and 13.95 forHBV and HCV respectively) and in married (7.79 and 3.92 for HBV and HCV respectively. The current studyconclude the high prevalence percentage of HBV (duplicate) than HCV with no seasonality of occurrenceand the Prisoners and foreigners, Surgery, blood donor and hemodialysis were mostly involved with HBVand HCV infection.
Cytotoxic Effects of Al-Yohedia Municipal Waste Water Wassan M. A. Al-Morshidy1 , Hussein O.M. Al-Dahmoshi2 , Ayad M. J. Al-Mammori3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12546

Abstract

Household waste water represent an hazardous reservoir for wide range of medically important pathogensthan can push an alarm on public health threatening diseases. It contain toxic materials, hazardous heavymetals and different pathogens. The study includes investigation of microbial, environmental, pathologicaland molecular effects of waste water. The results of dissolved heavy metals concentration revealed high Niconcentration (Mean±SD of four sites were 119.675±0.778 mg/L), high Mn concentration (Mean±SD of foursites were 108.2±1.095 mg/L), high Fe concentration (Mean±SD of four sites were 119.675±0.740.475±1.228mg/L), high Cd concentration (Mean±SD of four sites were 13.75±1mg/L), high Cu concentration (Mean±SDof four sites were 5±0.755mg/L) with no significant differences in concentration among four sites for Ni andCu while difference noted among Mn, Fe and Cd. Results of microbial study revealed that the Mean±SD ofCFU/ml were 1.97x1010±0.543 and the microbes were E. coli, K. pneumoniae, P. aeruginosa, V. cholerae,V. parahaemolyticus, S. aureus, E. faecalis, C. albicans, C. krusei and C. glabrata with MAR index rangedfrom (0-1). DNA damage results using comet assay for revealed that high level of damage to DNA of ratdosed with waste water compared with those dosed with fresh water in both tail length (11.35±2.1, 2.7±0.9)and tail moment (1.193±0.11, 0.2±0.1) respectively. Immunohistochemistry (IHC) assay was used to detectof 8-OHDG among liver tissues of rat dosed with waste water (study) and fresh water (control) and theresults revealed strong signal (high expression) in all liver tissues of rat dosed with waste water (study)compared with those dosed with fresh water (control) whose gave negative results. Histopathological resultsof eat dosed with waste water compared with those dosed with fresh water (control) were observed after 60days of dosing. the results displayed that the control was normal where mild chronic hepatitis showed insamples of site 1, 2, 3 while site4 had moderate chronic hepatitis and Fasciola hepatica. The current studyconclude that, Al-Yohedia Municipal wastewater is very dangerous and have different clinically importantpathogens along with different cytotoxic materials.
Antibacterial Effect of Virgin and Refined Coconut Oils on Pathogenic Bacteria: A Review Manar Saad Hussain1 , Farah Tareq Al-Alaq2 , Noor Salman Al-Khafaji2 , Hussein O. M. Al-Dahmoshi2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12548

Abstract

Virgin coconut oil (VCO) is the most oldest edible oil, extracted from fresh and mature kernel using wetor dry methods, therefor the resulting oil is a pure, clear, and colorless with a scent of fresh coconut, thesecharacteristics make VCO has the preferableness in medical and health applications, over refining coconutoil (RCO) that is extract from kernel of coconut after drying by methods makes the oil refining, bleaching anddeodorizing. In spite of that, the chemical compositions particularly the fatty acids in both VCO and RCOare the same with no significant difference. MCFAs which are classified as MCTs, are the basic componentsin both VCO and RCO, these MCFAs particularly lauric acid (LA) following by capric and caprylic acidsplaying a great role in antimicrobial activity of coconut oil, therefor the extraction of these fatty acids areshow more antibacterial activity on pathogenic bacteria more than lipolyzed VCO or VCO itself that maynot show inhibition effect. Gram positive bacteria is more sensitive than gram negative one towards LAand other fatty acids, therefor these fatty acids at high concentrations showed inhibition effect on gramnegative bacteria, while at low concentration showed resistance. This study attempts to review the chemicalcomponents in both VCO and RCO based on their extraction methods, also the antibacterial activity andthe mechanism of action, also suggests that RCO has the same effect as antibacterial as VCO based on theirchemical compositions.
Recent Advancements in Pulp Testing Devices Akansha Kishen1 , Anjaneyulu2 , N. P. Muralidharan3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12550

Abstract

Pulp vitality test is very crucial in monitoring and regulating the state of health of a dental pulp, especiallyafter the case of traumatic injuries. The dental pulp is considered to be the innermost part of the tooth. It issurrounded on all sides with dentine except near the apical foramina. This hard dentine casting around thepulp protects it from infection by microbes present in the mouth. The traditional pulp testing methods involvethermal and electric pulp testing methods. This conventional method basically depends on the innervationand often yields or records either false positive or negative response. The newer pulp testing devices, some ofwhich are still under developmental stage, detect the blood supply of the pulp, enumerate pulpal vasculature,check the vitality of the tooth etc. These newer technologies function by light absorption and reflectionmethods in. They are considered to be more accurate and non-invasive methods. The review article attemptsto discuss the recent advancements in various pulp testing devices related to pulp vitality testing in clinicalendodontic practice. It also describes the principle on which these newer pulp testing devices are basicallybased on its mode of working. The aim of this review paper is to highlight the difference between sensitivitytesting and vitality testing.
Knowledge and Awareness of Basic Life Support (BLS) among Dental Students Yoshita Guntupalli1 , K. R. Don2 , Krthik Ganesh Mohanraj3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12551

Abstract

Basic Life Support is an important life skill which should be taught to everyone. An emergency can happenat any time and any place and it is important that the people around the happening are trained to handle theemergency with utmost efficiency. This can be very helpful in reducing the number of deaths that occur. It isa must that all healthcare professionals have access to knowledge about BLS. In our study we aim to find outthe knowledge and awareness of BLS among dental students. A well structured, self-prepared questionnairewas circulated among dental students within the university of Saveetha Dental College. The students weresplit into three groups such as BDS students, Interns and MDS students. The confidence level was 95% andthe data was considered statistically significant if P value < 0.05. The results obtained were collected andanalysed to find out the awareness levels among the students and to find out which group had the highestknowledge on BLS. The data obtained was analysed and it was found that among the three groups the MDSstudents(42.86%) had the overall highest knowledge on BLS and CPR. The knowledge and awareness ofBLS among dental students was found to be moderate and not sufficient. Knowledge should definitely beimproved and more knowledge must be created.
Prevalence of Anemia among Women Patients Visiting A Dental Hospital Jagadheeswari Ramamoorthy1 , Gifrina Jayaraj2 , Geo Mani3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12552

Abstract

Anemia is the decreased oxygen carrying capacity of the blood due to reduction in the concentration ofHemoglobin or RBC. Anemia has a high prevalence and it is considered as a public health issue affectingdeveloped and developing countries. It occurs most commonly in women and children.Prevalence ofAnemia worldwide suggests the need for substantial improvement in the nutritional status of women.Theaim of the study is to assess the prevalence of Anemia among women patients visiting a Dental hospital.Patient records of a total of 86000 patients who visited the hospital between June 2019 to March 2020 werereviewed and the laboratory values of Hemoglobin levels and RBC count of women patients undergoingcomplete hemogram were collected from the case sheets of . The age, Hb% and RBC values were collected.The collected data was tabulated in Excel. It was then imported to SPSS software. Descriptive statistics wasperformed for the obtained results and comparison between groups were done by using Chi square tests.p<0.05 was considered as statistically significant. The prevalence of Anemia among the total women patientswas 39.1%. Among the 39.1% women who were diagnosed with anemia, it was found to be more prevalentin the women of age group 40-60 years with a frequency of 17.8%. The most commonly observed range ofHaemoglobin is 12-13g/dl with a frequency of 26.6% . 0.6% of women had RBC count less than 3 millioncells/mm3. A significant number of female patients were tested with abnormal results. The most commonage group diagnosed with Anemia are women belonging to 40-60 years of age. Routine hemoglobin testingin Dental practice of population at risk may be beneficial. Screening of Anemia is essential to avoid latediagnosis.
An Estimation of Haemoglobin Levels in Children with Early Childhood Caries- A Retrospective Study Ranjith Raj VPRB1 , Geo Mani2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.12553

Abstract

Aim: This study aimed to evaluate Haemoglobin (Hb) levels in children with Early Childhood Caries(ECC) and to find out whether there is any variation from normal values in Hb level in children with earlychildhood caries.Materials & Methods: In this retrospective study the Hb levels and dmft status of 281 children with ECCin the age group of 0 to 6 years were evaluated. The mean Hb values calculated were compared with thesuggested normal levels by the World Health Organisation for the particular age group. Kruskal Wallis testand post hoc test comparisons were done to compare differences in Hb levels in 4 different groups based ondmft values in children with ECC.Results: Overall mean value of Hb in children with ECC was 10.93 ± 1.73 g/dl and mean dmft was 7.19 ±4.3. Group 1 with less than 5 dmft value showed significant difference in Hb values compared to children ingroups with higher dmft values (p?0.05).Conclusions: Half of the study population had low haemoglobin levels i.e. below that of WHO criteria.Children with more than 5 dmft score had significantly lower Hb levels compared to children with less dmftvalues (p?0.05). There was no significant difference noticed in the Hb levels in between boys and girls withECC. This descriptive study results point that ECC can result in low Hb levels in children, however authorssuggest that an analytical study with a control group should be done to test the hypothesis.