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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
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Evaluation of CEA,CA19-9, and CA242 Tumor Markers in Patients with Colorectal Cancer by ELISA Technique Ahlam Shakir Hammood AL- Rubaiawi1 Mukhtar Khamis Haba1, Laith Raouf Ahmed AL- Hadad2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2809

Abstract

Colorectal cancer (CRC) is one of the common malignant tumors of gastrointestinal tract (GIT). A total of 40 patients with CRC were studied preoperatively and postoperatively while only 20 healthy persons were studied. Their ages ranged between 18-78 years.This study was carried out to investigate the possible association of some risk factors with CRC such as (age, gender, smoking, inflammatory bowel disease, and ulcerative colitis). With application of ELISA technique, Serum levels of CEA, CA 19-9, and CA 242 was measured preoperatively and postoperatively. The results showed an increase in preoperative serum level of CEA in CRC patients when compared to both postoperative and control groups, There was a significant increase in the serum level of CEA (10.73 ± 4.01) comparison with the two other groups (postoperative 3.95 ± 1.55) and control (1.91 ± 0.27) at (P<0.05), but no significant differences between the two groups (postoperative and healthy) which have mean (3.95 ± 1.55 and 1.91 ± 0.27) respectively. Also showed a significant increase in serum level of CA19-9 in patients preoperative (23.28 ± 1.86), who were differed significantly from the mean of serum in patients postoperative (18.63 ± 1.40) and control group (19.11 ± 1.46) at (P<0.05), When compared the serum level of CA242 revealed a significant increase in serum level of patients preoperative (19.58 ± 3.46) as compared to postoperative(8.75 ± 1.77) and control group(9.85 ± 2.22) at (P<0.05).
Knowledge about Emergency Contraception Pills among Primary Health Care Doctors in Baghdad\Al-Karkh Sector Waleed Arif Tawfeeq1, Amer Abaas2, Zaid Abdulateef Abdulkareem2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2810

Abstract

Background: Unintended pregnancy is associated with an increased risk of problems especially when woman is not in her optimal health for childbearing. The problem of unintended pregnancy and its complication can be reduced by the use of emergency contraception. Objective: To explore the knowledge of health care doctors in Baghdad/Al Karkh, Iraq regarding emergency contraception pills. Participants and Method: A structured questionnaire was distributed to a total of 390 primary health care doctors (obstetrics and gynecology specialists, general practitioners and family physicians). The questionnaire contained two main domains: demographic characteristics and knowledge about EC. Results: The majority of the sample were females 287 (73.6%), and the general practitioner (41.8%), family medicine specialists (34.6%). about one third of them were in age 40–49 years old, 72.1% of the physicians have no training about emergency contraceptive.. Conclusion: A deficit in knowledge shown by health care physicians lead to an insufficient use of emergency contraceptive pills methods.
Relationship of Vitamin D with Some Electrolytes in the Serum of People with Rheumatoid Arthritis in the City of Samarra Adeeb Mahfooth Farag Al-Samaria1, Kader Abdullah Shanak Al-Esawi2, Esraa Ali Abdul Kareem Al-Samaria
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2811

Abstract

The study was conducted on 50 samples of 30 patients with rheumatoid arthritis. The samples were divided into 15 females, 15 males and 20 control group (healthy) without any disease. The sample was divided into 8 females and 12 males. 80 years) and collected samples from Samarra General Hospital and outpatient clinics of the city. The blood was then collected from the healthy and sick people and separated by centrifugation. Biochemical variables were measured (vitamin D, glutathione , Mallon dialdehyde , uric acid). The results of the current study showed a significant decrease in the level of vitamin D in the serum of people with rheumatoid arthritis compared to healthy people, and the results showed a significant decrease in the level of glutathione in the serum of people with rheumatoid arthritis compared to healthy people, with no significant differences in Level of Mallon dialdehyde. We also note a significant increase in the level of uric acid in the serum of people with rheumatoid arthritis compared to healthy people.
Study of Thyroid Hormones for Vitiligo Patients in AL-Anbar Governorate Yasser Q. Hussein1 Wajeeh Y. Mohammed1 Abdulla S. Al-Hasan2, Sabri M. Al-marsomi1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2812

Abstract

Vitiligo is a common acquired depigmentation disorder characterized by the loss of functional skin and mucosal melanocytes the reported incidence is 0.5% to 2% worldwide. Its pathogenesis is mostly consider autoimmune and this pigmentary disorder is strongly associated with autoimmune thyroid disorders. To evaluate the serum thyroid hormone in vitiligo patients of Al-Anbar governorate and to compare the results with other external studies. The study group included 80 patients with vitiligo, and 40 healthy volunteers. Blood thyroid hormone was determined using Monobind kits from reliable USA company. Their ages ranged form 1 to 70 years. Family history of vitiligo was positive in a percentage of (30%) of the patients. The mean levels of serum thyroid hormone (T3, T4) in patients with vitiligo were found to be no significant difference than those of healthy individuals. The TSH level in patient with vitiligo were found to be significantly higher than those of healthy individuals. This study strengthens the relationship between the thyroid hormones intake, formation, and metabolism with the pathogenesis of vitiligo. Therefore it is concluded that vitiligo patients should be evaluated for thyroid hormones.
Detection of Quorum Sensing Signal Molecules and Identification of espB and Crt4 genes among Biofilm Forming of Citrobacter freundii Wathiq Abbas Hatite Al-Daraghi1, Mautham Khazaal Kadhim AL-Behadili1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2813

Abstract

150 samples from different clinical sources were collected from October 2018 to March 2019 from three hospitals in Maysan: Al Sadr General Education Hospital, Al Zahrawi Surgical Hospital and Maternity and Child Hospital to demonstrate the spread and distribution of Citrobacter freundii in several hospitals in Maysan. All isolates were identified based on morphological characteristics and biochemical tests. Results were confirmed by Api 20 E and Vitek 2 compact. A total of 14 isolates (9.3%) of 150 were found to be Citrobacter freundii. The isolates were considered as acute diarrhea in children, UTI, burns, wounds and most frequent ear swabs. PCR results showed that the LuxR 428bp genes were present in the Citrobacter freundii bacteria identified by previous diagnostic methods and this confirms the accuracy of the tests and methods used to determine this type.
The effect of Beta-amino Butyric Acid in Levels of Interleukin4 & Interleukin 10, Complement Proteins C3 & C4 and Immunoglobin IgM in Males Rats Sprague Dawley Infected with Pseudomonas aeruginosa Zainab Makki Sagheer1 Mohammad Abas Jasim1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2814

Abstract

B–amino butyric acid (BABA) non protein amino acid has effect on some immunological parameters of male rats Sprague Dawley species infected with pseudomonas aeruginosa. this study include 25 animal divided into five groups A, B, C, D and E each group contain five animals, A, B and C groups injected with three concentration of amino acid solution (25 mg\ml, 50 mg\ml and 75 mg\ml) with dose (0.2 g\ kg, 0.4g\kg and 0.6 g\kg) respectively, intra peritoneal weekly for six weeks, group D (first control group) and E (second control group) injected with normal saline. At the fifth week the four groups A, B, C and D exposed to pseudomonas aeruginosa, while group E did not exposed to infections after the termination of period of treatment, The blood samples were collected to do the immunological tests, the statistical analysis P<0.05 results showed BABA did not enhance sensitivity through measuring interleukin IL4, and significant increase of IL10 and complement protein C4, while BABA didn’t have a negative effect on the complement protein C3 activation and increase the level of immunoglobulin IgM.
The Toxic Effect of Cadmium Chloride on Lung Function and Tissue and the Protective Role of Pomegranate Seed Oil in Female Rabbits Noor Ibrahem Hasan AL-Kraie1, Israa Salman Dalas1; Qasim Azeez Razooqi1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2815

Abstract

The experiment was designed to determine the protective role of pomegranate seed oil on lung function and tissue against cadmium chloride toxicity. In this experiment, 20 animals (rabbit females) were used. Lung efficiency was measured by measuring the size of red blood cells and hemoglobin, as well as studying the histological effects of cadmium chloride against lung tissue and the protective role of pomegranate seed oil . The results showed that the treatment of animals with cadmium chloride at a dose of 5 mg / kg bw for 30 days led to a significant increase in packed cell volume (PCV) and hemoglobin (Hb) compared to control group . The treatment of animals with cadmium chloride has also shown that there is no possibility of distinguishing the alveolar of lung (AV) with the presence of focal infiltration of the inflammatory cells with a marked thickening of the wall of the blood vessel (TW) with blood congestion (CON) Pomegranate seed oil improves most of the negative effects caused by cadmium chloride .
A Biometric Assessment of a Combined Topical Levofloxacin, Retinol, Cloxacillin and Ascorbic acid Against Facial Acne Naser A Naser1, Hussein Abdulkadhim A2, Sahar A. Alhar3, Karrar K. Alhaidary4, Rana Talib Al-Nafakh4
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2816

Abstract

Acne vulgaris is a common pilosebaceous lesion affects skin over the face and upper chest. It has about 14 million incidence rate that cost 100$ for each case. In this study, biometric outcomes of the combined retinol, levofloxacin, cloxacillin, ascorbic acid and the hydrocarbon base vehicle on different types of acne lesions in human were investigated. Twenty one person were included in two groups; test (N =10) and control (N = 11) with follow up of objective software based biometric analysis parameters including: keratolysis induction, redness reduction and healing of infected lesion. The test formula revealed a significant keratolysis induction as compared with control. Eight out of 10 individuals with the test formula had keratolysis in comparison with 2 out of 11 had no keratolysis in controlled group, P-Value = 0.005. Similar effects were obtained in redness reduction (redness reduction ratio induced with test formula = 2.5 with confidence interval CI over 0.95) and impetiginization healing at P < 0.05. From the overall results, the combined retinol, levofloxacin, cloxacillin, ascorbic acid and the hydrocarbon base vehicle showed significant improvement in biometric outcomes of facial acne lesions.
Assessment the Efficacy of Arthrocentesis with Corticosteroid and Arthrocentesis with Sodium Hyaluronate in Treatment Temporomandibular Joint Disorders: A Comparative Study Samer Majeed Mohammed1, Muntathar Muhsen Hassan Abusanna2, Zina Ali Daily3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2817

Abstract

Background: Temporomandibular joint disorders (TMD) refer to a group of heterogeneous pain and dysfunction conditions involving the masticatory system, reducing life quality of the sufferers. Aim of study: The aim of the study was to evaluate the effectiveness of arthrocentesis with corticosteroid (betamethasone) injection and with sodium hyaluronate injection in treatment temporomandibular joint disorders, in conjunction with a stabilizing splint, for improving function and reducing pain, for preventing further deterioration of the TMJ dysfunction, to maintain improvements over time, and compare between them. Patients and methods: Fifty –four patients with TMJ disorders with age limit between 18 and 55 years of age, 9 males and 36 females, were enrolled in this study. Patients were randomly divided into two groups, in which one group received arthrocentesis with intra-articular corticosteroid (betamethasone) injection (1 ml), and another group received arthrocentesis with intra-articular sodium hyaluronate injection (1 ml) in superior joint space ,in single puncture. Patients were followed at regular interval of 7th day, one month, 3, 6, 9, 12 months (follow up) after last injection. Results: The mean age of patients was 8.873 ± 34.112 years in Group-A treat by betamethasone and10.973± 33.27 years in Group-A treat by sodium hyaluronate (ranged from 18.2 to 55.0 years).
Aqueous Extract of Date Palm Fruit (Phoenix dactylifera) Protect Liver Against Cyproterone Acetate Toxicity in Male Mice Nuha Yaarub Al-Harbi1, Eman Fadhel Abbas Awadh1, Wasan Najim Abdul-Sada2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2818

Abstract

The cyprote.rone acetate (CPA) is an antiandrogen drug that is used in the treatment of prostate cancer, which is related to drug-induced liver injury (DILI). The aim of this study the effect of the water extract of one of the local dates on the side effects of using cyproterone acetate on liver tissue in white mice. Forty from albino mice male were divided into 8 equal groups received orally in one ml as follows. Group 1: distilled water passive control, group 2: corn oil positive control, group 3: received with 5 mg/kg body weight CPA , group 4: received, with 20 mg/kg CPA, group 5: received with 5 mg/kg CPA & 60 mg/kg date palm extract, group 6: received, with 5 mg/kg CPA & 120 mg/kg date palm extract, group 7: received , with 20 mg/kg CPA & 60 mg/kg date palm extract, group 8: received with 20 mg/kg CPA & 120 mg/kg date palm extract lasted for 21 days. Showed a histological study of the liver remarkable degeneration of hepatocytes associated with interstitial necrosis and blood vessel congestion. The current study proved that the water extract of dates has a weak effect in the repair of damage in the liver tissue to treatment for the low dose of cyproterone acetate only

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