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INDONESIA
Indian Journal of Forensic Medicine & Toxicology
Published by Official Organ of Indian Association of Medico-Legal Expert
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Public Health
Arjuna Subject : Kedokteran - Epidemilogi
Articles 5,497 Documents
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Assessment of Transdermal Vasodilatatory Effect of a Combined Panthenol, Amlodipine, Isosorbide Dinitrate and Betahistine HCl on Peripheral Vessels Hussein Abdulkadhim A1, Naser A Naser2, Fadhaa A. Ghafil3, Rana Talib Al-Nafakh4, Karrar K. Alhaidar
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2829

Abstract

Peripheral vascular diseases are group of disorders characterized by stenozing peripheral circulation as a complication of primary disease like diabetes mellitus. Peripheral vascular diseases affect 202 million around the world. Peripheral vascular complications of diabetes mellitus are common which affect 30 million over the world and may give rise to infectious necrotizing sequalae called diabetic foot. In a trial of assessment for transdermally applied vasodilator drugs, 30 individual had participated in a case controlled study. Test group (N =11) and control group (N =19) were assessed for the signs of vasodilatation over the dorsum of the hand and figure blood perfusion detection. There was significant increase in perfusion index (from 7 to 11) induced by the test vasodilator as compared with control (from 7 to 8) P <0.05 and parallel results were obtained in induction of redness (redness ratio of 7 with C.I. over 0.95 and thermal increase in degrees of ( C ) over the dorsum of the hand in comparison with the control group. From the overall results the combined vasodilatatory transdermal formula caused a significant peripheral vasodilatation which could be a candidate therapeutic effect in diabetic foot
Evaluation of Using Titanium Mesh in the Reconstruction of Traumatic Orbital Floor Fracture Mukhalled Salim Alasady1, Ihsan Abdullah Kumail 1, Alyaa Turky Alsultany2, Ali B. Roomi3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2830

Abstract

Background: Among the nonresorbable implants, Titanium mesh is the most common graft used for orbital reconstruction. It is continuously improved to achieve accurate restoration of orbital volume. To evaluate the using of Titanium mesh for the reconstruction of traumatic orbital floor fractures. Patients and Methods: A total of (32) patients were enrolled in this study where operated under general anesthesia to repair the orbital floor fractures by using titanium mesh, and they were ( 24 ) males and (8) females. (16) patients had Enophthalmos,( 10) patients had Diplopia,(6) patients had both enophalmos with diplopia; all patients had ecchymosis, Subconjunctival hemorrhage, Parasthesia of infraorbital nerve. Results: The results were well represented as the following: (29)patients(90.62%) had no both diplopia & enophthalmos. Postoperative complication had been found in only( 3) patients (9.3%), Two patients(6.25%) had diplopia, one patient (3.1%) had Enophthalmos. Conclusions: Titanium mesh has a long track record of reconstruction of large orbital floor defects and correction of globe malposition.
Association of Epstein- Barr Virus (EBV) with the Development of Nasopharyngeal Carcinoma (NPC) in Western Region of Iraq: Unmatched Molecular Case-Control Study Mothana Ali Khalil1, Arkan Obaid Jasim Al-Essawi2, Mohammed Tafash Dagash3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2831

Abstract

Background: Nasopharyngeal Carcinoma (NPC) is uncommon in Iraq, but its incidence is raising due to increased exposure to diverse risk factors. Many of the NPC-related risk factors are becoming more and more apparent in Iraq. The exactly risk factors for nasopharyngeal carcinoma (NPC) in Anbar province, Iraq are not known. Objectives: To determine the association between Epstein- Barr virus (EBV) infections and other risk factors with the development NPC of Iraqi patients. Patients and Method: Sixty-seven paraffin-embedded tissues of NPC cases, 134 normal noncancerous nasopharyngeal biopsy samples, and tonsillectomy specimens from patients with chronic hypertrophic tonsillitis as controls were enrolled in the study that was conducted between 12 January 2012 and 21 January 2019. DNA of EBV was extracted from both controls and neoplastic tissues and analyzed by PCR technique using primers specific to EBV Latent Membrane Protein-1 Oncogene (LAMP-1) for the presence of EBV. A Questioners data form for all patients and controls were filled by the researchers regarding other risk factors of NPC including the patient’s age, sex, residence, radiation exposure, history of chronic rhinitis, family history of NPC, tobacco smoking, alcohol consumption, herbal medicines, tea consumption, exposure to formaldehyde and exposure to different inhalants. Results: The following risk factors were found to be independently associated with illness: EBV (adjusted odds ratio [OR] 7.852, 95% confidence interval [CI] 2.22–27.72), herbal medicine (OR 19.051, CI 7.56– 47.95) and Family history of NPC (OR 63.717, CI 6.67–607.96). Conclusion: Combination of family history of NPC , EBV exposure and herbal medicine was a strong risk factor for NPC.
Molecular Detection of Toxogenic Cyanobacteria Isolated from Tigris River in Baghdad City –Iraq Zainulabdeen H. A. AL-Khafaji1, Ahmed S.Dwaish2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2832

Abstract

Algae and their contamination are being increasingly reported worldwide that cause a serious hazard to environmental and human health. Cyanotoxin was the most algal toxin reported to be produce by several orders of cyanobacteria. In 2017 cyanobacteria were isolated from fresh water of Tigris River and identified by light compound microscope as well as conventional PCR. Five isolates of cyanobacteria which successfully amplified a gene fragment from the phycocyanin shared by all cyanobacteria and only four isolates successfully amplified a gene fragment from the myc E belonged to microcystin. Our results concluded that PCR assay can be used for early detection of microcystin producing algae in fresh water that useful to stations responsible for the preparation of drinking water.
Flame Atomic Absorption Spectrophotometry Analysis of Heavy Metals in Some Food Additives Available in Baghdad Markets, Iraq Wasan Abdulwahid Jasim1, Jassim Dawood Salman2, Jasim Mohammed Shamar Jamur3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2833

Abstract

Flame atomic absorption spectrophotometer (FAAS) was used in this study to determine the concentrations of heavy metals such as Ca, Fe, Mn, Cd, Co, Cr, Ni, Cu, Pb and Zn in some food additives of Iraq. The order of metal contents in food additives was found to be Ca ? Mn ? Fe ? Cu ? Zn ? Pb ? Cr ? Ni ? Co ? Cd. The concentration level of each metal was compared with that recommended by food agriculture organisation (FAO) and world health organisation (WHO). Calibration curves were linear for all standard solutions of heavy metals in the range starting from 0.02-0.4 mg/kg for Cd to 11-100 mg/kg for Ca. The correlation coefficients values (R2) of calibrations were investigated and ranged from 0.9971 for Cr to 0.9999 for Ca. The limit of detection (LOD) and limit of quantification (LOQ) were found to be in highest value for Ca (1.6569 mg/kg and 5.5232 mg/kg), while they were found to be in lowest values for Cd (0.0150 mg/kg and 0.0499 mg/kg).
Detection Malta Fever by Interferon-gamma and Steroid Hormone S Level Ali Anok njum1, Layla Saleh Abdul-Hassan2 Ihasan A. Hashem3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2839

Abstract

Malta fever is one of the most common bacterial zoonosis, its causes abortion of pregnant women. Abortion is the chief obvious manifestation of Brucella infection. Brucella like better cattle placenta as a result of great concentration of erythritol sugar, whereas human placenta there is no erythritol sugar only steroid hormone, for this reason designed the our project . In this study, 100 aborted women were included , where referred to maternity and children hospital of Babylon province \ Iraq. Diagnosis of Brucella infection in these abortions was concentrated on serological and bacteriological technique. Serological studies included the use of RB and ELISA tests. Aggressive differences between RB and ELISA results have been shown. Brucella isolated and identified from aborted placenta and blood samples were 7 (7%) isolates from aborted women. Hormonal assessment by Immunohistochemical technique in Brucella infected women, showed significant decrease in progesterone expression in comparison with that aborted due to other causes, in other hand Brucella infected women showed high expression in estrogen hormones . ELISA technique was the valuable serological test to confirm the diagnosis of brucellosis as compared with RB test.
Hepatic Toxicity in Patients with Rheumatoid Arthritis and Psoriasis Taking Methotrexate Therapy Haider Hamza Omran1, Basim Mohammed Mothlum1
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2842

Abstract

Background: We had made a study to demonstrate the adverse hepatic effects of MTX in patients taking MTX for treatment of RA and psoriasis taking in consideration the following variables: BMI, gender, cumulative dose, age, weekly dose, duration of treatment, serum level of cholesterol and creatinine. Patient and method: We had a prospective study of 85 patients with RA and 50 patients with psoriasis. All patients were analyzed by history, clinical examination and investigations in the form of liver enzymes, blood sugar, serum cholesterol, serum creatinine, HBS Ag and anti HCV antibody. Persistently elevated level of liver enzymes 2 to 3 times the upper limit of normal on two occasions 3 months apart indicate hepatic toxicity Results: We found that 7 patients with psoriasis and 6 patients with RA have significant elevated liver enzymes which reflect MTX hepatotoxicity Conclusion: Our study show that patients with psoriasis at significantly greater risk of elevated liver enzymes than patient with RA (14% and 7% respectively) were gender, BMI, cumulative dose, weekly dose and serum cholesterol level are risk factors for hepatic toxicity due to MTX therap
Scolicidal Activity of Zirconium Oxide (ZrO2) nanoparticles Against Protoscolices of Hydatid Cysts Amenah Abdul-Jabbar Ibrahim
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2843

Abstract

Hydatidosis is a sickness that affects human and farm animals. This disease is deemed as a public health problem in different regions of the world until nowadays. Surgical overlaps is the best way to treat the disease, while the risk of surgery lies in the possibility of cyst rupture and leakage of protoscolices and the recurrence of infection again, this prompted researchers to use scolicidal agents before surgery such as ethanol, plant extracts, to reduce parasite spread and recurrence of infection, recently researchers have been using nanoparticles as a scolicidal agent, like gold nanoparticles, silver nanoparticles, selenium nanoparticles, and others. This research aims to evaluate the fatal effect of zirconium oxide (ZrO2) nanoparticles to protoscolices of hydatid cysts. The Protoscolices were collected from sheep livers infected with hydatid cyst disease. The protoscolices were treated with different concentrations (250, 500, 1000, 2000, and 4000 ?g/ ml) of ZrO2 NPs. The viability of protoscolices was determined by using an eosin staining method after 15, 30, and 60 min. The results showed that the concentrations of 1000, 2000, and 4000 µg/ml were significantly effective in the killing of protoscolices after 60 min., where the fatality rate of protoscolices was 49.6%, 52.7%, and 53.1% respectively when compared with the control group 38.5% (p<0.05).
Molecular Study of Fimh Gene in Klebisella Pneumoniae Isolated From Urinary Catheter Patients Israa Abdul Ameer Al-Kraety1, Zahraa Hameed Oda Alquraishi2, Aqeel A Alsadawi3
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2846

Abstract

This study aimed to isolate and diagnose K. pneumoniae from clinical specimens of urine from urinary catheterized patients and molecular Detection of FimH fimbrial adhesin in Klebisella pneumonia in Najaf governorate from October 2018 to March 2019, which includes 40 clinical specimens (urine). The diagnosis of K. pneumoniae isolates was based on culture and biochemical characteristics as an initial diagnosis. The final diagnosis by the Vitek-2 compact system is automated besides the use of PCR technique to detect on fimH fimbrial adhesion gene. The biochemical results showed that 40/40 isolates gave positive result of K. pneumoniae.These results were confirmed by Vitek showed that 40/40 were positive for K. pneumoniae isolated and PCR technique by using fimH gene where 14/40 were positive for K. pneumoniae isolated from urine urinary catheterized patients. The study, which was conducted in the diagnosis of bacteria, concluded that the technique of compact Vitek-2 automated. The ability of bacteria to stick to the formation of biofilm was investigated by phenotypic method.
Chemerin Level as a Marker in Preeclampsia and its Relation to the Disease Severity and Neonatal Outcome Ali Mohammed Murad, Marwa Jaafar Sadac (M.B.Ch.B)2; Hanan Hazim Mohammed Noori (M.B.Ch.B, C.A.B.O.G,
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i2.2848

Abstract

Aim of study: To detect serum chemerin level in patient with preeclampsia and evaluate the association between maternal serum chemerin, disease severity and neonatal outcome. Patients and Method: A case control study included 100 pregnant women with singleton pregnancy, gestational age of 20 weeks or more, normal fetal morphology, and absence of concomitant diseases, who were collected from inpatient during delivery was conducted in the Department of Obstetrics and Gynecology at Al-Yarmouk Teaching Hospital during the period from 1st of June 2018 till end of May 2019. They were divided into three groups (control, mild preeclampsia, and severe preeclampsia). Patients with history of chronic hypertension, diabetes mellitus, cardiovascular disease, neurological disorder, renal impairment, or premature rapture of membrane were excluded from this study. blood sample was taken from all patients and sent for human chemerin assay. After delivery, birthweight of baby, APGAR scores at one and five mints, neonatal intensive care unit and adult intensive care unit admission, and hospitalization time were also noted. Results: There were no statistically significant differences between the study groups in age, BMI level, and parity. Chemerin level was significantly elevated in patients with severe preeclampsia (435.06 ng/ml) and mild preeclampsia (227.49 ng/ml) than that in non-preeclamptic patients (202.6 ng/ml). It was negatively correlated with each of gestational age, birth weight, Apgar score at one and five minutes. While it was positively correlated with admission’s duration. Serum chemerin > 228.5 ng/ml is predictive for diagnosis of preeclampsia and level > 380.9 ng/ml is indicator for severe preeclampsia. Conclusion: Chemerin may play a role in the pathogenesis of preeclampsia as maternal serum chemerin level was significantly higher in patients with preeclampsia

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