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<![CDATA[Evaluation of Risk Factors and Outcome of Incarcerated Inguinal Hernia in Pediatric Age Group ]]>
<![CDATA[Ibrahim Tariq Ameen1, Raid Hamid Abdul-Ghafoor2, Bilal Hamid Abdul-Ghafoor3]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i1.53
<![CDATA[Background: Incarcerated inguinal hernia is one of emergency conditions in children. It results from entrapment of bowel or other viscera within the hernia sac. High incidence of incarcerated inguinal hernia occurs in young age and preterm. The incidence of incarcerated hernia is variable and ranges from 12–17%. The aim is to evaluate the risk factor / or factors and outcomes for patients with incarcerated inguinal hernia.Patients and method: This prospective study directed in department of pediatric Surgery, Central Child’s Teaching Hospital, Baghdad, Iraq. Fifty-five patients with incarcerated inguinal hernia were managed for 10 months. They were evaluated for history and sent for investigations. All patients initially treated by manual reduction. Later on they treated by elective operation. Overall outcomes were evaluated in all patients.Results: The patient`s age range from 17 days to 5.5 years. There was male predominance with male: female ratio was 10:1. The frequency of right side incarcerated inguinal hernia was more than the left. Fourty (72.7%) patients were under first year. Thirty-two (58.2%) patients were preterm. Fourty-four (80%) patients have successful manual reduction and eleven (20%) patients were failed and underwent emergency surgery. Intestinal resection done to 4 patients and rate was 7.3%, and orchiectomy done to 3 patients and rate was 5.4%.Conclusion: Premature and younger age patients are risk factors for incarcerated inguinal hernia. Incarceration increases the rate of overall complications. Any patient, especially young patient and preterm, with reducible hernia should be treated as soon as possible.]]>
<![CDATA[Harmonic Scalpel Vs Conventional Cautery Use In Hemorrhoidectomy ]]>
<![CDATA[Khalid K. Hussein]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i1.54
<![CDATA[Introduction: The evidence-based literature emphasizes the requirement of prioritizing harmonic scalpel haemorrhoidectomy over the conventional surgical interventions in the context of minimizing the intra-operative and post-operative complications in the treated patients.Aim: The presented research study evaluated the significance of the harmonic scalpel (HS) as compared to the conventional electrocautery in the context of facilitating safe and effective haemorrhoidectomy in the selected patients. The study question focusses on analysing the potential of HS haemorrhoidectomy in terms of minimizing the post-operative complications in the patients affected with grade III and IV hemorrhoids. The study hypothesized beneficial treatment outcomes of HS haemorrhoidectomy as compared to the conventional electrocautery-based haemorrhoidectomy.Methodology: The prospective cohort study shortlisted 20 candidates for HS and electrocautery-based haemorrhoidectomies. Initial 10 patients underwent the conventional haemorrhoidectomy; however, the other 10 received HS haemorrhoidectomy.Result: The research findings categorically revealed limited post-operative pain and bleeding in the harmonic scalpel group as compared to the conventional electrocautery group. HS haemorrhoidectomy substantially reduced the extent of collateral thermal damage in the treated patients.Conclusion: The study findings affirmed the effectiveness of HS haemorrhoidectomy over traditional intervention in terms of minimizing postoperative complications including bleeding, pain, urinary incontinence, fecal incontinence, anal stricture, and anal abscess.]]>
<![CDATA[The Implementation of Hiradc Method in Computer Laboratory ]]>
<![CDATA[M. Affan Mahfudz1, Putri Ayuni Alayyannur1, Dani Nasirul Haqi1, Abdul Rohim Tualeka1, Fauziah Mukti ]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i1.55
<![CDATA[The computer laboratory of the Faculty of Public Health, Universitas Airlangga is used as a research site, measurement or scientific training for about 15,000 students. There are various types of activities which are at high risk, especially in the use of electricity, which can cause short-circuit and leads to fire. The objective of this study was to apply the Hazard Identification, Risk Assessment and Determining Control (HIRADC) methods in the computer laboratory as an effort to prevent occupational accidents and illness of the user. This study was an observational research using cross sectional design. The observation was conducted on the source of hazard and control efforts on the computer laboratory. Interview was conducted on the lecturers and administrative staff who are in charge of the computer laboratory. The results of the hazard identification indicated that there were 17 hazard sources that can cause 18 risks. Based on the risk assessment conducted on a activities practicum, there are 18 risks classified into 2 risk levels, those are 3 risks with moderate risk level and 15 risks with low risk level. The three level of moderate risks include taking off the shoes in standing position which can cause sprains, there is no first aid box and using electric current which can cause short circuit, electric shock and fire risk. The control that can be carried out by management laboratory to reduce the three moderate risk are by giving advice to taking off the shoes in sitting position, covering the socket which has risky placement by using duct tape to avoid the risk of electric shock as well as the provision of a light fire extinguisher for fire risk and the last providing first aid kits to treat the accidents that occur in the laboratory as soon as possible.]]>
<![CDATA[Evaluation of Factors Affecting Quality of Nursing Cares for Dying Patients in ICUs ]]>
<![CDATA[Mahnaz Varedi Kolahi1, Mohammad Ziae Totonchi Bagheri2, Hooman Bakhshandeh3, Reza Ghanei Gheshlagh4,]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i1.56
<![CDATA[Nursing managers have paid special attention to quality assessment as an important management tool for improving nursing performance and the quality of nursing care. This study aimed to evaluate the aspects and factors involved in the quality of nursing cares for dying patients in ICUs in 2016-7. This descriptive and analytical study was conducted in ICUs of Imam Khomeini Hospital Complex and Shahid Rajaei Cardiovascular Medical & Research Center, Tehran.In total, 191 working nurses were selected via convenience sampling. Data collection tool was quality patient care scale (QUALPACS). In addition, data analysis was performed in PSSS version 20 using descriptive and inferential statistics. The mean score for end-of-life care was 83.62±8.62 in the psychosocial, 85.36±7.74 in the communication and 92.23±10.88 in the physical aspects. According to the results, a significant relationship was observed between passing educational courses related to end-of-life care and quality of end-of-life care in the physical (P=0.002), psychosocial (P=0.02) and communication (P=0.01) aspects. According to the results of the study, the quality of care for dying patients was higher in the physical aspect, compared to other aspects. However, the quality of nursing care was poor in the psychosocial aspect.]]>
<![CDATA[Effect of Crude Bacteriocin Isolated from Locally Lactococcus lactis on Cancer Cell Lines ]]>
<![CDATA[Mariam T. Abbdul -Kaliq1, Khetam H. Rasool1 and Rajwa Hasen Essa1]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i1.57
<![CDATA[Lactococcus lactis is a Gram-positive bacterium used widely in the production of cheese and buttermilk, but has moreover become well-known as the first genetically modified organism to be used alive for the treatment of human diseases. This study was designed to display the efficacy of lactococcus lactis, which was isolated from raw cow’s milk isolated by using the liquid MRS agar, culture, and microscopically was tested moreover, chemically was also tested to check the presence of (catalase, oxidase, protease production, gelateinase, clot formation). The isolates were confirmed using molecular diagnosis. The Bacterial isolates were developed on the M17 liquid medium at 30 °C for 24 hrs to obtain the raw bacteriocin after separation by centrifuge. The toxicity and bacterial susceptibility was tested as well the effect of Bacteriocin on E.coli, P.aerugionsa, staph.areus. The results showed a clear inhibitory effect of bacteriocin on pathogenic bacteria. The toxic effect of crude bacteriocin was investigated and its effect on cancer cell lines of breast cancer cells (MCF-7) lymphoid cell line (CCL-119) using different concentrations of the extract. The toxic effect was also examined on normal liver cell lines (WRL) with a 72 hrs incubation period. The results show a clear and high-significant effect of crude bacteriocin on cancer cells. It was also observed that the severity of toxicity increased with the increases of concentration with no effect on normal cell lines.]]>
<![CDATA[New Bio-Therapeutic Candidate for Pancreatic Cancer ]]>
<![CDATA[Marwah Saad Joudah1, Basma Talib Al-Sudani2, Inam Sameh Arif1]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i1.58
<![CDATA[SIRT1 is NAD+-deacetylases, several histone and non-histone proteins which their involvement in metabolic processes, cell growth, apoptosis, and senescence are well known. Several Sirtuins targets are implicated in cancer. SIRT1 is both an oncogene and tumour suppressor, and it can act in this capacity depending on the kind of tissue and the cancer etiology. Subsequent studies in this field are going to make evident the exact function of SIRT1 at the cancer site and it is hoped that new chemotherapeutic functions of SIRT1 activators are going to be determined. In accordance with this, it is suggested that very selective ligands such as aptamer was created and investigated in various pancreatic cancer cell lines for the regulated activity of SIRT1. This study seeks to establish the therapeutic impact of the activator SIRT1 aptamer as a pharmacological model of pancreatic cancer by evaluating the impacts of activators SIRT1 (aptamer) on the growth of a series of human pancreatic cancer cell lines (AsPC-1, Capan-2, BxPC-3). Results gotten from in vitro cytotoxicity assays revealed that circular aptamer BAS inhibited the growth of pancreatic cancer cell lines [BxPc-3 (80%), Capan-2 (83%) and Aspc-1 (82.8%)] at 72h with IC50 0.55, 0.5, 0.76 ?M respectively. Importantly, circular aptamer showed no reduction of cell viability on the non- pancreatic cancerous H6c7 cell line, implying it might be safe to non-cancerous tissue. Our results indicate that the SIRT1 activated by aptamer could a promising targeted therapeutic approach for pancreatic cancer.]]>
<![CDATA[Infanticides in Dakar: Medico-Legal Aspects ]]>
<![CDATA[Mohamed Maniboliot Soumah1, 2, Peace Renée Senami Akokbegan3, Mor Ndiaye1]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i1.59
<![CDATA[Infanticide is a crime that evokes emotion and misunderstanding in the general population. The overall objective was to assess the current situation regarding the killing of new-born children in Dakar. This is a cross-sectional, descriptive study spread over a 12-year period from 1 January 2004 to 31 December 2015. The study population was women accused of infanticide incarcerated in the prison and correctional facility of Liberté 6 and who had either been tried or who were awaiting trial during the study period. The 46 cases tried concerned 47 newborns and one mother having killed both her babies. The victims were found especially in the mother’s home (28 cases) For all women in our sample, the murder was motivated by personal, social and economic factors. The average age of the mothers was 25.5 years with the youngest being 17 years old and the oldest 41 years old. These detention periods ranged from 2 to 6 years. The average length of pre-trial detention was 3.26 years, The preventive strategies put in place in some countries are proof that prevention against these acts remains possible.]]>
<![CDATA[Changes in Some Urinary Variables After Potassium Citrate Therapy In Patients With Recurrent Urinary Stone Disease In Tikrit City, Iraq ]]>
<![CDATA[Mohammed Mohsin Abdul-Aziz1, Nihad Nejres Hilal2, Mohanned Hussam Mohammed Saeed Alkumait3]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i1.60
<![CDATA[Objective: to determine the effect of oral potassium citrate (k-citrate) on urinary calcium, magnesium, volume, and pH in patients with recurrent stone disease.Patients & Method: Interventional clinical trial study was implemented from June 2016 to February 2019 in Tikrit city, Iraq. 94 patients with recurrent urinary stone disease were enrolled in this study. Oral k-citrate therapy was given to patients in a dose of 15 meq three times daily for 2 weeks. Patients instructed for 24 hours urinary collection before and after therapy. Urinary calcium, magnesium, volume, and pH were measured before and after therapy to examine the effect of k-citrate.Results: mean age was 38.5 (SD 17.4) years. Male patients were 64% while 36% of patients were females. Mean urinary calcium level decreased significantly after k-citrate therapy, p value < 0.001. Mean urinary volume and pH increased significantly after therapy, p value < 0.01 and < 0.05 respectively. No significant change was identified in mean urinary magnesium level after therapy, p value = 0.14. No adverse effects related to k-citrate therapy were reported by patients during study period.Conclusion: Urinary volume and pH increased significantly in patients after potassium citrate therapy. Also k-citrate therapy significantly produced marked decrease in urinary calcium level. No change was observed in mean urinary magnesium level before and after k-citrate therapy. No adverse effects related to k-citrate therapy were reported by patients during study period.]]>
<![CDATA[Synthesis and Characterization of Some Bis-Nitroaryl Pyrazolonesand Estimation of Their Anti-Bacterial and Anti-Fungal Activities ]]>
<![CDATA[MuathJabbarTarfa Al-Abbasee1, Hamid J. Mohammad2, Mawlood K. Mawlood1]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i1.61
<![CDATA[A simple and efficient one-pot synthesis of bicyclic nitro pyrazolone derivatives in traditional alcoholic solvents under refluxing conditions, The chemical structure of the synthesized derivatives was substantiated byFT-IR,1H NMR ,13C-NMRand CHNS analysis, All of these compounds of the series have been testedin vitro asantibacterial and antifungalagents against four types of organisms. The minimum and maximum inhibitory concentrations were determined against each organism.]]>
<![CDATA[Assessment of the Correlation between the Salivary Flow Rate and Dental Caries Experience among Children with ?-Thalassemia Major ]]>
<![CDATA[Mudhafar Fadhil Jaddoa1, Alhan Ahmed Qasim2]]>
<![CDATA[ Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology ]]>
Publisher : <![CDATA[Institute of Medico-legal Publications Pvt Ltd ]]>
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DOI: 10.37506/ijfmt.v14i1.62
<![CDATA[Thalassemia constitutes a group of congenital blood disorders which characterized by a defect in synthesis of one or more globin chains of human hemoglobin molecule and the resultant microcytosis and hypochromia of the RBCs. It is of two main divisions, ?- and ?-thalassemia and several other subdivisions. The study group composed of 40 patient years previously diagnosed with ?-thalassemia major attending the thalassemia center in Thi-Qar province/Iraq. The control group, matching the age and sex of the study group, and consisted from 40 child selected from a number of primary schools. Unstimulated salivary samples was taken from each subjects under standardized conditions. The mean value of flow rate of saliva was lower among ?-thalassemias (0.466±0.024) than for controls (0.829±0.048). The (mean±SE) for the primary teeth (dmfs) in ?-thalassemias (1.450±0.324) was higher than that for controls (1.250±0.808), this difference was not significant (P> 0.05). The (mean±SE) of the caries experience (DMFs) in ?-thalassemias (6.850±0.782) was higher than for the control group (3.600±0.489).]]>
