cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Yolanda Handayani
Contact Email
yola.aksel@gmail.com
Phone
+6282157048069
Journal Mail Official
respirologyscience@gmail.com
Editorial Address
Jalan Cipinang Bunder No. 19, Cipinang, Pulogadung, Jakarta Timur, DKI Jakarta 13240, Indonesia
Location
Kota adm. jakarta timur,
Dki jakarta
INDONESIA
Respiratory Science
Published by Perhimpunan Dokter Paru Indonesia
ISSN : -     EISSN : 27471306     DOI : https://doi.org/10.36497/respirsci.v1i3.17
Core Subject : Health,
Health Professions Medicine & Pharmacology
Focuses on original article reviews and case reports in pulmonary and critical care medicine Scope: 1. Asthma 2. Chronic Obstructive Pulmonary Disease (COPD) 3. Lung Physiology and Sleep-Related Disorder 4. Lung Infection 5. Thoracic Oncology 6. Interstitial Lung Disease 7. Environmental Lung Disease 8. Tobacco Control 9. Occupational Pulmonary Disease 10. Pulmonary Intervention and Emergency Medicine 11. Respiratory critical care 12. Respiratory immunology and biomolecular
Arjuna Subject : Kedokteran - Kedokteran Paru dan Pernafasan
Articles 123 Documents
 9   10   11   12   13 
Role of Interventional Pulmonology in Palliative Care Wahju Aniwidyaningsih; Ni Putu Laksmi Ananda Martini
Respiratory Science Vol. 6 No. 2 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i2.200

Abstract

Interventional pulmonology (IP) is a minimally invasive approach that plays a pivotal role in the evaluation and management of advanced thoracic diseases within palliative care. By integrating bronchoscopic and pleural techniques, IP provides effective symptom relief without the need for extensive surgical procedures or prolonged hospitalization. In malignant central airway obstruction, stenting, cryotherapy, and laser debulking offer rapid improvement in airflow and quality of life. For malignant pleural effusion, thoracentesis, pleurodesis, indwelling pleural catheters, and intrapleural fibrinolytic therapy for septated effusions provide safe and cost-effective strategies for symptom control. In selected cases of severe emphysema, bronchoscopic lung volume reduction using endobronchial valves improves lung mechanics and exercise capacity. In contrast, one-way endobronchial valves and spigots are valuable in managing persistent air leaks. With high procedural success rates and favorable safety profiles, IP is broadly applicable across diverse palliative respiratory conditions. Overall, IP provides a safe, effective, and patient-centered solution that complements standard palliative care, ensuring optimal quality of life while minimizing invasive burden.
Shoulder Pain as The First Clue: A Case Report of Pancoast Tumor with Early Presentation Muhammad Akbar Ramadhan Munandar; Ira Kusumastuti; Liana Herlina; Hendra Priatna Munandar
Respiratory Science Vol. 6 No. 2 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i2.202

Abstract

Background: In some cases, shoulder pain can be an early sign of a serious condition, such as a Pancoast tumor. A Pancoast tumor is a type of lung cancer located in the upper lobe of the lung. These tumors are often difficult to diagnose because their symptoms are similar to those of musculoskeletal conditions. Case: A 68-year-old man presented with a three-month history of right shoulder pain. The pain had been treated with analgesics and acupuncture but showed no improvement. The patient reported experiencing shortness of breath over the past few days. The patient had a history of smoking and unintentional weight loss. A chest X-ray revealed atelectasis and a suspicious mass in the superior lobe of the right lung. A chest CT scan confirmed the presence of a mass in the superior lobe of the right lung. A biopsy was performed to confirm the diagnosis, which revealed poorly differentiated small cell carcinoma in the right lung. The patient was subsequently diagnosed with a Pancoast tumor (with staging T4N3M1a). Discussion: A pancoast tumor is a condition which oftenly overlooked due resemblane of musculoskeletal disorders. Shoulder pain caused by this tumor may result from the tumor invading surrounding tissues. It is important for physicians to perform a thorough evaluation of patients presenting with shoulder pain, especially when risk factors are present. Conclusion: Shoulder pain as an early symptom of a Pancoast tumor is an important clinical concern for healthcare professionals. Early detection through comprehensive and appropriate evaluation can significantly improve patient prognosis.
Improving Awareness and Screening of Obstructive Lung Disease in Post-Tuberculosis Patients: A Community Service Program at Depok Fannie Rizki Ananda
Respiratory Science Vol. 6 No. 2 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i2.215

Abstract

Background: Post-tuberculosis lung disease (PTLD) is a rising public health concern despite the urgency of eliminating the active infections of tuberculosis (TB). Even after successful treatment, almost half of patients continue to have limitations related to respiratory complaints, particularly dyspnea and chronic cough. This has resulted from airway and parenchymal destruction. This study was conducted as a community service program at Bhakti Yudha Hospital, Depok, to provide education and early screening of respiratory disorders in post-TB patients. Method:  This study consisted of material presentations on risk factors, warning signs of respiratory disease, and prevention of post-TB complications, followed by screening using the modified Medical Research Council (mMRC) dyspnea scale and spirometry. Patients with serious respiratory complaints will get a consultation session with the pulmonologist. The activity was carried out from May to June 2025 and involved 50 patients who had completed 6 months of TB therapy. Results: Reported that participants presented with dyspnea of varying severity: mMRC 1–2 (18%), mMRC 3 (56%), and mMRC 4 (26%). Among these, 84% of patients with mMRC >2 had a history of extensive pulmonary lesions at initial diagnosis. Spirometry revealed that 94% of patients exhibited moderate to severe mixed obstructive-restrictive impairment. Conclusion: This study highlights the importance of screening for respiratory complaints after TB treatment, the early recognition of exacerbations, and the continuation of pulmonary rehabilitation in post-TB care.
Malignant Pleural Effusion: A Contemporary Approach to Diagnosis and Personalized Management Theresia Rasta Karina; Hana Khairina Putri Faisal; Mia Elhidsi
Respiratory Science Vol. 6 No. 2 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i2.214

Abstract

Malignant pleural effusion (MPE) is a manifestation of advanced malignancy characterized by abnormal accumulation of pleural fluid due to tumor cell infiltration. It most commonly originates from lung, breast cancer, or lymphoma and is associated with dyspnea, chest pain, and impaired quality of life. Diagnosis of MPE is established through pleural fluid cytology or histopathological confirmation, supported by radiological imaging. Liquid biopsy offers a minimally invasive approach for detecting molecular alterations. Although diagnostic and therapeutic modalities have improved, management remains primarily palliative. Therapeutic thoracentesis, chemical pleurodesis using talc, and indwelling pleural catheter (IPC) placement are the main palliative strategies. Combination therapy of IPC with talc slurry demonstrates higher rates of spontaneous pleurodesis and shorter hospital stays. Systemic therapies such as chemotherapy, targeted therapy, and immunotherapy provide additional disease control in selected patients. Although current approaches have improved diagnostic and therapeutic outcomes, most treatments remain palliative. Therefore, a multidisciplinary and personalized strategy is essential to optimize patient quality of life. This review underscores the importance of early diagnosis and management of malignant pleural effusion, including cytology, pleural biopsy, imaging, and liquid biopsy, as well as therapeutic approaches such as thoracentesis, pleurodesis, indwelling pleural catheter, systemic therapy, and palliative care.
Pulmonary Function Characteristics and Asthma Control Profiles Among Adult Asthma Patients at A Referral Hospital In Indonesia: A Retrospective Study Susanthy Djajalaksana; Andriana Adolf Nggay; Abdul Malik Fajri; Fahnida Nazliah; Rahma Djamaludin; Aditya Sri Listyoko
Respiratory Science Vol. 6 No. 2 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i2.228

Abstract

Background: Asthma is a heterogeneous chronic airway disease characterized by variable respiratory symptoms and airflow limitation. In secondary healthcare settings, objective assessment using spirometry is often underutilized, and discrepancies between symptom-based assessment and lung function may occur. This study aimed to describe the demographic, clinical, and pulmonary function characteristics of asthma patients and to examine their relationship with asthma control at Lawang Hospital. Method:  This retrospective cross-sectional study included asthma patients who underwent spirometry at the Pulmonology Outpatient Clinic of Lawang Hospital between 2022 and 2023. Medical record data included demographics, smoking history, comorbidities, atopic history, asthma symptoms, asthma control assessed using the Asthma Control Test (ACT) and Global Initiative for Asthma (GINA) criteria, spirometric parameters, and prescribed therapies. Pulmonary function patterns were classified as obstructive, restrictive, mixed, or normal. Associations were analyzed using chi-square tests, meanwhile correlations between ACT scores and spirometric values were assessed using Spearman’s correlation. Results: Among 173 patients, most had a history of atopy (70.52%) and no family history of atopy (60.12%). Good asthma control based on ACT was observed in 72.83%, whereas only 1.16% were well-controlled according to GINA criteria. Most were partially controlled (89.60%) and had at least one asthma-related risk factor (78.03%). Pulmonary function patterns were obstructive (39.31%), restrictive (20.23%), mixed (27.17%), and normal (13.29%). No significant associations were found between patient characteristics and asthma control (P>0.05). Only the FEV1/FVC ratio showed a weak but significant correlation with ACT scores (P=0.012). Conclusion: Asthma patients demonstrated diverse pulmonary abnormalities with limited correlation between symptoms and spirometry. Routine spirometry remains important to complement clinical assessment.
Risk and Prevention of Infections in the Bronchoscopy Room Wahju Aniwidyaningsih; Indah Puspita Sari; Anis Karuniawati; Fathiyah Isbaniah; Mia Elhidsi; Ni Putu Laksmi Ananda Martini
Respiratory Science Vol. 6 No. 3 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i3.217

Abstract

Bronchoscopy is a widely used diagnostic and therapeutic procedure in pulmonary medicine, with increasing utilization as technology advances. However, it is also associated with a risk of infection, which may negatively impact patient outcomes, particularly in individuals with underlying lung disease or immunocompromised conditions. The Centers for Disease Control and Prevention (CDC) has reported that endoscopic procedures, including bronchoscopy, are among the most frequently implicated medical devices in healthcare-associated outbreaks. Post-bronchoscopy infections, although relatively uncommon (0.2–5.2%), may lead to serious complications such as pneumonia, lung abscess, and empyema. These infections can originate from endogenous respiratory flora or from exogenous contamination related to inadequate bronchoscope reprocessing. This narrative review aims to summarize current evidence on infection risks, sources of transmission, and preventive strategies in the bronchoscopy setting, including occupational risks to healthcare workers. Strengthening infection control practices is essential to improve patient safety and reduce the risk of transmission in bronchoscopy units.
Air Pollution and Respiratory Diseases in South Tangerang: A Literature Review Abdul Rahman; Mukhtar Ikhsan
Respiratory Science Vol. 6 No. 3 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i3.220

Abstract

In cities, air pollution ranks high among the most pressing problems affecting both the environment and people's health. Research has demonstrated that gaseous pollutants like ozone (O3), sulfur dioxide (SO2), and nitrogen dioxide (NO2), as well as fine particulate matter (PM2.5 and PM10), greatly increase the prevalence of respiratory diseases like asthma, chronic obstructive pulmonary disease (COPD), and acute respiratory infections (ARI). To investigate the effects of air pollution on public health, especially in South Tangerang City, and the correlation between the two, this article provides a thorough literature analysis. The literature search results indicate that air pollution plays a role in the occurrence of ARI, asthma, pneumonia, and COPD through oxidative stress, long-term inflammation, and immune system disorders. Data from local and regional levels show that PM2.5 levels in South Tangerang frequently exceed WHO-recommended limits, particularly during certain periods, increasing the potential for respiratory health problems among urban residents. These emphasize the importance of integrated, evidence-based efforts to control air pollution to protect public health and support sustainable urban development.
Role of Flexible Bronchoscopy in Respiratory Management of Critically Ill Patients: A Retrospective Analysis Sylvia Sagita Siahaan; Allen Widysanto; Titis Dewi Wahyuni; Victor Nugroho Wijaya; Magdalena Sirait; Emily Wibowo Otto
Respiratory Science Vol. 6 No. 3 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i3.221

Abstract

Background: Respiratory disorders are a major challenge in the ICU, with 30-50% of patients requiring mechanical ventilation. Flexible bronchoscopy provides direct visualization of the airways and plays a critical role in pulmonary diagnosis and therapy. Although widely used in intensive care units (ICUs) worldwide, data on its effectiveness and safety in Indonesian ICUs remain limited. Method: This is a descriptive, retrospective study using medical records data from patients aged 15 to 85 years who underwent mechanical ventilation in the ICU. Purposive sampling was used, with a sample size of 140. Data were analysed using Microsoft Excel and SPSS. Results: Of 140 samples, most were male (65%), with a mean age of 57.64 years. Comorbidities were present in 83.7%, primarily cardiovascular disease (28.8%). The most common indication was combined diagnostic and therapeutic purposes (45.7%). Chest X-ray improvement was observed in 75.7% of patients. FiO2 requirements increased after bronchoscopy. Most bronchoscopy findings indicated infection (60%), and hypoxemia was the most frequent complication (9.3%). Conclusion: Flexible bronchoscopy is a safe and effective diagnostic and therapeutic procedure.
Enhancing Quality of Life Through Palliative Care in the Elderly with Severe Chronic Obstructive Pulmonary Disease and Multimorbidity: A Case Study Muhammad Ilham Dhiya Rakasiwi; Amalia Ghaisani Putri; Windu Prasetya; Permadita Wicaksono
Respiratory Science Vol. 6 No. 3 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i3.225

Abstract

Background: Chronic obstructive pulmonary disease (COPD) patients experience significant problems arising from dyspnea, ultimately affecting their quality of life (QOL). Knowledge of palliative care for chronic or terminal diseases has developed, but its application in severe COPD is limited. This case presents an elderly patient with a COPD exacerbation and analyzes palliative care studies related to QOL in COPD. Case: A 65-year-old man presented to the emergency ward with severe dyspnea for 7 days, followed by a productive cough with greenish-yellow sputum. The QOL assessment using the EQ-5D-5L questionnaire showed severe discomfort and problems with daily activities. After pharmacologic interventions for the acute exacerbation, the medical team provided palliative care consisting of symptom management and a multidimensional assessment to address the patient’s symptoms and offer spiritual support. After 7 days of treatment, spirometry showed an FEV1/FVC of 39% and 36% for pre- and post-bronchodilator, respectively. Post-hospitalization QOL showed only slight problems in the discomfort/pain component. Discussion: Based on five studies about the role of palliative care in the HRQOL of COPD patients from a systematic literature search, all studies showed no statistically significant differences between COPD patients receiving palliative care and standard care. The outcomes of this case differ from previous studies, possibly because this patient had psychosocial needs during his treatment that the medical team could help fulfil, thus improving his HRQOL. Conclusion: The literature review on the role of palliative care in hospitalized COPD patients found limited evidence of its benefits. While recommendations from respiratory societies support palliative care, this case highlights improvements in QOL following palliative care during hospitalization.
Prognostic Significance of Absolute Neutrophil and Eosinophil Counts in AECOPD in Kolonel Abundjani Bangko General Hospital: A Retrospective Study Hafifah Hafifah; Derallah A Lindra; Diniwati Mukhtar; Helwiyah Umniyati; Endang Purwaningsih; Ahmad Rusdan H Utomo; Faisal Yunus
Respiratory Science Vol. 6 No. 3 (2026): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v6i3.230

Abstract

Background: Chronic obstructive pulmonary disease (COPD) is a chronic and progressive respiratory condition characterized by persistent airflow obstruction. The disease trajectory is often punctuated by episodes of acute exacerbation, which significantly aggravate clinical status and increase healthcare burden. The biological plausibility and differential inflammatory pathways of these cell populations suggest evaluating the relationship between neutrophil and eosinophil profiles and the one-year exacerbation frequency in patients with acute COPD. Method: This study was conducted using a retrospective observational analytic design and included all patients with a confirmed diagnosis of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) who fulfilled the established inclusion criteria at Kolonel Abundjani Bangko General Hospital during April to December 2024. Clinical and laboratory data were retrieved from hospital medical records and subsequently analyzed using appropriate statistical methods. Results: Thirty-eight patients fulfilled the predefined inclusion criteria and were subsequently enrolled in the analysis. The respondents were predominantly male (94.7%), older than 55 years (89.5%), with a documented smoking history (92.1%), with relatively short admissions (1–4 days) in 68.4%, and survival at discharge was observed in 94.7% of patients. Inferential statistical testing demonstrated no significant relationship between neutrophil or eosinophil counts and clinical prognosis in patients experiencing AECOPD (P>0.05). Conclusion: Neutrophil nor eosinophil counts demonstrated a statistically significant association with prognostic indicators among patients admitted with acute COPD. However, elevated neutrophil levels (>8) were consistently more prevalent across prognostic strata compared with increased eosinophil counts. This distribution pattern suggests a relative predominance of neutrophil-mediated inflammatory activity during acute exacerbations.

Page 12 of 13 | Total Record : 123

 9   10   11   12   13 

Filter by Year

2020 2026


Reset
Filter By Issues
All Issue Vol. 6 No. 3 (2026): Respiratory Science Vol. 6 No. 2 (2026): Respiratory Science Vol. 6 No. 1 (2025): Respiratory Science Vol. 5 No. 3 (2025): Respiratory Science Vol. 5 No. 2 (2025): Respiratory Science Vol. 5 No. 1 (2024): Respiratory Science Vol. 4 No. 3 (2024): Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science Vol. 4 No. 1 (2023): Respiratory Science Vol. 3 No. 3 (2023): Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science Vol. 3 No. 1 (2022): Respiratory Science Vol. 2 No. 3 (2022): Respiratory Science Vol. 2 No. 2 (2022): Respiratory Science Vol. 2 No. 1 (2021): Respiratory Science Vol. 1 No. 3 (2021): Respiratory Science Vol. 1 No. 2 (2021): Respiratory Science Vol. 1 No. 1 (2020): Respiratory Science More Issue