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Britain International of Exact Sciences Journal (BIoEx Journal)
Published by BIAR Publisher
ISSN : 26861216     EISSN : 26861208     DOI : https://doi.org/10.33258/bioex
Core Subject : Health, Science, Education,
Biochemistry, Genetics & Molecular Biology Chemistry Mathematics Medicine & Pharmacology Physics
Britain International of Exact Sciences Journal is a peer-reviewed journal published in January, May and September by BIAR Publisher. BIoEx Journal welcomes research paper in mathematics, physics, chemistry, biology, engineering, medical sciences, argicultural sciences and other related fields which is published in both online and printed versions.
Arjuna Subject : Matematika - Matematika (Lain-Lain)
Articles 190 Documents
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Anti-Dislipidemia Effectiveness Test of Turmeric Ethanol Extract (Curcuma Longa) in Male Wistar Mice Given a High-Fat Diet Wang Lei; Florenly; Liena; Fioni
Britain International of Exact Sciences (BIoEx) Journal Vol 4 No 1 (2022): Britain International of Exact Sciences Journal, January
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v4i1.543

Abstract

Dyslipidemia is a condition of increasing levels of Low Density Lipoprotein (LDL), cholesterol in the blood, or triglycerides in the blood that can be accompanied by a decrease in levels of High Density Lipoprotein (HDL). Herbal products have been used since long ago in the medical world, one of which is curcuma longa root. The main compound of turmeric is curcumin which can lower cholesterol levels due to inhibiting cholesterol reabsorbtion from the outside and increase the enzyme HmgCoA reductase inhibitor so that fat synthesis can run properly. The purpose of this study was to find out the effectiveness of turmeric ethanol extract (Curcuma Longa) as an anti-dyslipidemia in male wistar rats given a high-fat diet. This experimental study with the pre-test and post-test group only control design approach was conducted in January 2021, at the Herbarium Medanese FMIPA USU. The size of the sample was calculated by Federer's formula, with at least 4 mice in each treatment group. The results and conclusions of turmeric ethanol (Curcuma Longa) III (150.20 ± 0.90 mg/dl) significantly decreased total cholesterol compared to the control group (177.50 ± 6.02mg/dl) (P value < 0.05). Turmeric ethanol extract (Curcuma Longa) III (110.00 (109-112) mg/dl) may significantly lower triglyceride levels compared to the control group (166.50 (160-175) mg/dl), (value P = 0.024). Turmeric ethanol extract (Curcuma Longa) III (66.50 ± 1.25 mg/dl) significantly lowered LDL levels compared to the control group (106.20 ± 3.50 mg/dl), (P value < 0.05). Turmeric ethanol extract (Curcuma Longa) III, (60.00 (59-61) mg/dl) can significantly increase HDL levels compared to the control group (27.00 (33-39) mg/dl), (Value P = 0.024). Turmeric ethanol extract (Curcuma Longa) III significantly lowered SGOT (Value = 0.024) and SGPT (Value P < 0.05) compared to the control group.
Knowledge Relationship with Maternal Anxiety in Breastfeeding Babies during the Covid-19 Pandemic at UPTD Puskesmas Bawomataluo in 2021 Alfirida Simanungkalit; Anastasia Luahambowo; Lisbet.E.F.Siregar; Dear Sari Br. Purba; Chrismis Novalinda Ginting
Britain International of Exact Sciences (BIoEx) Journal Vol 4 No 1 (2022): Britain International of Exact Sciences Journal, January
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v4i1.544

Abstract

Breast milk is the main food source for babies who contain a variety of vitamins, proteins, and fats. However, with the increase in the Covid-19 pandemic, many mothers do not breastfeed their babies, because they are worried that their babies will contract the Covid-19 virus. This is due to the lack of information obtained by mothers, that the Covid-19 virus cannot be transmitted through breast milk. This study aims to find out the relationship of knowledge with maternal anxiety in breastfeeding in infants during the Covid-19 pandemic. This type of quantitative research with an analytical descriptive approach, conducted at UPTD Bawomataluo, November to December 2021. A population of 61 nursing mothers, a large determination of the total sampling sample. Univariate data analysis and bivariate analysis, Chi-Square test, a significant level of 0.05. The majority of respondents had less knowledge than 43 respondents (70.2%). The majority of respondents had a severe anxiety level of 31 respondents (50.8%). The results of bivariate analysis of knowledge relationship and anxiety level obtained value p-value = 0.000 < = 0.05. Concluded, it can be concluded that there is a meaningful relationship between the level of knowledge and anxiety levels of breastfeeding mothers in the Covid-19 pandemic.
Effect of Boswellic Acid Administration on Blood Biochemical Profile of Sprague Dawley Rats in Cyclophosphamide-Induced Cardiotoxicity Conditions Miranti Fardesiana Putri; Ietje Wientarsih; Bayu Febram Prasetyo; Vetnizah Juniantito
Britain International of Exact Sciences (BIoEx) Journal Vol 4 No 2 (2022): Britain International of Exact Sciences Journal, May
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v4i2.660

Abstract

Cyclophosphamide (CP) is a chemotherapeutic agent that belongs to the alkylating agent group that is widely used in the treatment of cancer. Cardiotoxicity is often a side effect of using CP in medical therapy. In this study, 24 Sprague Dawley rats were randomly divided into 4 groups. Group 1 (K1) was given injection with aqua pro injection intraperitoneally (IP) once a week for 21 days. Group 2 (K2) was given IP CP with a dose of 50 mg/kg BW, once a week for 21 days. Group 3 (K3) was given boswellic acid extract at a dose of 250 mg/kg BW orally, every day for 21 days. Group 4 (K4) was given boswellic acid nanoparticles at a dose of 250 mg/kg BW orally, every day for 21 days. During the treatment the body weight of the rats was weighed every day. At the end of the treatment, the rats were euthanized and blood samples were taken for blood biochemical evaluation, namely CPK, LDH, AST, and ALT. The results showed that the levels of CPK, LDH, AST, and ALT in K2 were significantly higher (p<0.05) than K1, K3 and K4. Statistically, the results of CPK, LDH, AST and ALT in K3 and K4 were not significantly different (p<0.05) compared to K1. The two groups (K3 and K4) were not significantly different (p<0.05) but on average the CPK, LDH, AST, and ALT results in K4 had lower scores than K3. This can indicate the protective effect of boswellic acid and boswellic acid nanoparticles on the heart against cyclophosphamide-induced cardiotoxicity.
Unambiguous Identification of Objects in Different Environments and Conditions Based on Holographic Machine Learning Algorithms Evgeny Bryndin
Britain International of Exact Sciences (BIoEx) Journal Vol 4 No 2 (2022): Britain International of Exact Sciences Journal, May
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v4i2.726

Abstract

Unambiguous provision of results in different environments and conditions by machine learning algorithms is an unresolved problem until now. Solving the problem of machine learning with unambiguous provision of results in different environments and conditions can be approached by focusing on the psychophysical holographic process of human learning. A person, with a mental concentration of attention, experimentally teaches vision, hearing, psyche and mind in a holographic way and in a resonant way to perceive, recognize and recognize phenomena, processes, objects, subjects, meanings, music and other entities in various environments and conditions. A person experimentally teaches the psyche and feelings to rationally navigate in various environments and conditions. Holographic algorithms of experienced machine learning will help neural network ensembles to unambiguously recognize objects, subjects, music, texts in various environments and conditions using a model of recognizing their own or someone else's. Machine learning simulates holographic processes of human communication memorization of entities. Searching for objects in different environments in different conditions based on experienced machine learning simulates resonant associative processes of human entity detection. By simulating holographic processes of the human psyche based on artificial intelligence of machine learning with Fourier transformation, using full parametric sequences of necessary and sufficient data of holograms of target objects, it is possible to solve the problem of their unambiguous detection in different environments and in different conditions.
Modeling the Thermal Behavior of the Viscoelastic Properties of Asphalt Concrete Saad I. Sarsam
Britain International of Exact Sciences (BIoEx) Journal Vol 4 No 2 (2022): Britain International of Exact Sciences Journal, May
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v4i2.729

Abstract

The viscoelastic properties of asphalt concrete are susceptible to the variation in the pavement temperature. In the present work, asphalt concrete beam specimens were prepared at optimum binder content and tested under repeated flexural stresses for fatigue life. Three testing temperature were implemented (5, 20, and 30) ℃. The variation in the phase angle, dissipated energy, flexural stiffness, and permanent deformation due to the testing temperatures were monitored and modeled. It was concluded that the viscoelastic properties of asphalt concrete are highly sensitive to the variation in testing temperature. The phase angle and the permanent deformation increases sharply as the testing temperature rises. However, the dissipated energy and the flexural stiffness declines as the testing temperature rise. Mathematical models were obtained which can be implemented in identifying the thermal behavior of the viscoelastic properties of asphalt concrete.
Breeding of the Giant African Edible Snail (Achatina achatina Linnaeus, 1758) in Gbado-Lite city, Democratic Republic of the Congo Koto-te-Nyiwa Ngbolua; Ruphin Djoza Djolu; Michael Dibere Selenga; Jean-Bernard Bosanza Zanyako; Colette Masengo Ashande; Clarisse Mawi Falanga; Moises Mawunu Monizi; Jonas Mbongu Sodi Nagahuedi
Britain International of Exact Sciences (BIoEx) Journal Vol 4 No 2 (2022): Britain International of Exact Sciences Journal, May
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v4i2.730

Abstract

The objective of this study was to evaluate the effect of the nature of the food ration on the size, weight, weight gain and ex situ reproduction of the snail (Achatina achatina) in Gbado-Lite. The results of this work show that variations in size [from 8.2±1.2 cm at feeding (D0) to 9.9±2.1 cm at day D84 (snail farm A) and from 8.4±1.1 cm to 10.2±1.8 cm (snail farm B)]; hatching rate [88.2% (snail house A) and 94.2% (snail house B)]; weight [460±18.5 g at loading (D0) to 760±26.3 g on day D84 (snail house A) and 475±10.9 g to 760±26.3 g (snail house B)]; mean absolute weight gain 84 days after loading [37.7±12.0 g (snail house A) and 36.5±9.6 g (snail house B)] were not statistically different between snail houses including mean daily weight gain (0.450±0.1 g/d vs. 0.363±0.1 g/d) and survival rate (90% vs. 100%). Both formulations have the same effect on the reproduction of Achatina achatina in captivity. It is therefore desirable that more in-depth studies be conducted with the aim of popularizing this non-conventional breeding in the city of Gbado-Lite. Thus, in the current context of biodiversity erosion linked to human activities as well as environmental factors, snail farming can contribute to empowerment, improved socio-economic conditions and household resilience to climate change.
Survey of Edible Caterpillars in Gbado-Lite City (North Ubangi, Democratic Republic of the Congo) and Medicinal Value of Their Host Plants Koto-te-Nyiwa Ngbolua; Robijaona Rahelivololoniaina Baholy; Rakotondrazafy Jennie Irma Norosoa; Ruphin Djoza Djolu; Colette Masengo Ashande; Felix Mboka Mune; John Koyanza Wangombe-Dawe; Michel Mobale Mongeke; Jean-Jacques Domondo Amogu; Blaise Mbembo-Wa-Mbembo; Moises Monizi Mawunu
Britain International of Exact Sciences (BIoEx) Journal Vol 4 No 2 (2022): Britain International of Exact Sciences Journal, May
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v4i2.731

Abstract

The purpose of this study was to conduct a survey of edible caterpillars and the ethno-medical value of their host plants in Gbado-Lite using the "snowball" sampling technique. The results of this study show that Anaphe panda, A. venata, Elaphrodes lactea, Imbrasia epimethea, I. oyemensis, I. truncata and Pseudanthera discrepans are the most consumed caterpillars. Drying is the most used preservation method (82.4%); ground collection is the most used harvesting method (86.3%) while evisceration (45.1%) and dehairing (33.3%) are the main cooking methods used. Harvesting is done more in the forest (94.1%) from May to July (86.3%). The vast majority (98%) of host plants are used in traditional medicine; leaves (53%) and bark (45%) are the most used parts, while decoction is the most used method of preparing therapeutic recipes (92%). The felling of trees (39%) and traditional agriculture (26%) are to varying degrees the main causes of the disappearance of edible caterpillars and their host plants. Incomplete cooking (78.4%) and/or the host plant (19.6%) are the main causes of consumer poisoning. It is therefore desirable that sustainable participatory management strategies for edible caterpillars and their host plants be put in place in North Ubangi Province. These include community agroforestry, which should be practiced in peri-urban areas in order to strengthen the resilience of communities to climate change while at the same time fighting hunger and poverty. Indeed, the domestication of species would allow annihilating the pressure on wild resources, to conserve them, to fight against deforestation and to ensure the availability and sustainability of edible caterpillars. Those phytochemical, pharmacological and toxicological studies could be carried out on host plants in order to identify compounds of medical interest contained in these plants.
Survey on Household Solid Waste Management in Gbado-Lite city (Nord-Ubangi) in the Democratic Republic of the Congo Koto-te-Nyiwa Ngbolua; Ruphin Djolu Djoza; Gina Wediani Ngbaisi; Colette Masengo Ashande; Clarisse Falanga Mawi; Monizi Mawunu; Clément Inkoto Liyongo; Jeff Iteku Bekomo
Britain International of Exact Sciences (BIoEx) Journal Vol 4 No 2 (2022): Britain International of Exact Sciences Journal, May
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v4i2.732

Abstract

Household solid waste management is a crucial issue for environmental and human health. The purpose of this study was to conduct a survey on household solid waste management in Gbado-Lite (Nord-Ubangi) in the Democratic Republic of Congo (DRC). A household solid waste survey was conducted in 5 neighborhoods of the city of Gbado-Lite in northern DRC from July to August. Data collection was made possible by stratified probability sampling and direct observations. The results of this study revealed that the main informants (75%) were women and 68% of the respondents were in the 18-35 age group. The main socio-cultural groups in the study area are the Ngbadi (55%) and Ngbaka (16%). In addition, 74% of respondents have secondary education and their main sources of income are commerce (25%), the civil service (20%) and the household (13%). Also, the main solid household wastes identified were organic materials (44%) and packaging (25%); the majority (56%) of respondents did not have garbage cans and used plastic buckets without lids as their main garbage can (75%). Almost all (98%) of the waste does not undergo primary separation. The main waste disposal methods used by households are: landfill (43.87%), abandonment on public land (30.62%) and incineration (18.36%). Finally, the main harms of waste reported are: typhoid fever (29%), malaria (25%) and mosquito proliferation (24%). It is therefore desirable that a public sanitation service be set up in Gbado-Lite to enable households to manage their solid waste properly and thus protect the urban environment and human health.
Effect of Feeding Fermented Catfish Pellets with Probiotics on Population Growth of Water Fleas (Daphnia Magna) Cantika Glodia; Sucahyo
Britain International of Exact Sciences (BIoEx) Journal Vol 4 No 3 (2022): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v4i3.736

Abstract

D. magna as feed has advantages: easy to digest, the size is in accordance with the larval mouth opening, has 42.65% protein in the form of nutrition, contains a number of digestive enzymes, does not degrade water quality and can be cultivated in bulk. In this study, commercial catfish pellets fermented with probiotics were used as feed for D. magna. The probiotic that is often used in aquaculture is EM4 (Effective Microorganism 4). EM4 is able to play a role in increasing protein levels and with the right dose, EM4 becomes the main determining factor in growth productivity. The purpose of this study was to determine the good duration of EM4 fermentation in population growth of D. magna. This study is an experimental study (CRD), using D. magna as a test animal, with 5 different treatments. The results of the density of D. magna which were given different treatments gave different results. The highest density was found in treatment 3 and the treatment that had the lowest density was in treatment 5. The results of the Nonparametric test (Friedman-Test) showed significant results (P=0.00<0.05). Significantly different treatments were in treatment 3 and 5, while treatment 2 and treatment 4 had no significant difference. The results of the study the highest specific growth rate obtained was in treatment 4 of 0.223%/day, then followed by treatment 3 of 0.211%/day, while other treatments were relatively lower. Thus, feeding in the form of catfish pellets fermented with EM4 on the population growth of Daphnia magna gave a significant effect on treatment 3 and treatment 5 with the highest specific growth rate in treatment 4.
Survey on Knowledge and on some Cases of Monkeypox: A Zoonotic Disease Endemic to Ubangian Eco-region of Democratic Republic of the Congo Koto-te-Nyiwa Ngbolua; Ruphin Djolu Djoza; Jeff Iteku Bekomo; Colette Masengo Ashande; Clarisse Falanga Mawi; Emmanuel Kitete Mulongo; Dorothée Tshilanda Dinangayi; Damien Sha Tshibey Tshibangu; Muhammad Ridwan; Pius T. Mpiana
Britain International of Exact Sciences (BIoEx) Journal Vol 4 No 3 (2022): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v4i3.737

Abstract

The aim of this study was to investigate knowledge on Simian Orthopoxvirosis or Monkeypox in 180 people (129 males and 51 females) using the stratified probability sampling method. The majority of the respondents were (are): 35-50 years old (45.00%), with secondary education (43.33%), farmers (40.56%) and married (80.00%). The disease appears every year, thus demonstrating its endemic nature (98.33% of the respondents); 58.3% of the respondents said that the disease appears very often during the dry season, on the contrary, 40% of the respondents said that the disease appears during the rainy season. However, 1.7% of respondents said that the disease occurs every other season. The majority of respondents (81.1%) said that the cause of the disease is the consumption of bush meat, followed by wild vegetables (3.3%), fish (2.8%), livestock (2.2%) and caterpillars (1.7%) respectively. 65.2% of the respondents use Manihot esculenta to treat the disease locally, and followed by the leaves and wine of Raphia sese (13%), Morinda morindoides (13%) and Myrianthus arboreus (8.7%). Between January 17 and September 10, 2020, 40 cases of monkey pox were admitted to HGR of Businga (Maximum age: 42 years, minimum age: 1 year, average age: 13.3 years). 28 patients were male and 12 female. It is therefore advisable that surveillance be organized in wild animals and bush meat exposed on the market to ensure that they are not contaminated with Monkeypoxvirus. It is thus needed to establish a veterinary laboratory in Nord-Ubangi Province.

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