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FORTE JOURNAL
Published by Universitas Haji Sumatera Utara
ISSN : -     EISSN : 27744655     DOI : https://doi.org/10.51771/fj
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
FORTE JOURNAL adalah jurnal resmi yang diterbitkan oleh Prodi Farmasi Fakultas Ilmu Kesehatan Universitas Haji Sumatera Utara yang artikelnya dapat diakses dan unduh secara online oleh publik. Jurnal ini adalah jurnal peer-review nasional, yang terbit dua kali dalam setahun yaitu pada bulan Januari dan Juli. Forte Journal memuat tentang topik-topik keunggulan hasil penelitian di bidang pelayanan dan praktek kefarmasian, pengobatan masyarakat, teknologi kefarmasian serta disiplin ilmu kesehatan dan sains yang terkait erat. Jurnal ini menerima naskah berbahasa Indonesia dan Inggris. Berikut merupakan area-area yang difokuskan oleh jurnal ini: 1. Obat Bahan Alam dan Obat Tradisional 2. Farmasi Klinis dan Komunitas 3. Farmasetika dan Teknologi Farmasi 4. Kimia Farmasi 5. Biologi Farmasi 6. Farmakologi Farmasi, dan 7. Sains yang terkait dengan bidang kesehatan Naskah yang terpilih untuk dipublikasikan di Forte Journal akan dikirim kepada reviewer yang ahli dibidangnya, yang tidak berafiliasi dengan lembaga yang sama dengan penulis dan dipilih berdasarkan pertimbangan tim editor. Proses review dilakukan secara tertutup dimana penulis dan reviewer tidak mengetahui identitas dan afliasi masing-masing. Setiap naskah yang didelegasikan ke anggota redaksi diperiksa untuk keputusan akhir proses review, komentar dan saran akan dikirim ke penulis untuk menanggapi ulasan reviewer dan mengirim kembali naskah revisi dalam waktu yang telah ditentukan. Naskah yang diterima untuk publikasi adalah salinan yang diedit untuk tata bahasa, tanda baca, gaya cetak, dan format. Seluruh proses pengajuan naskah hingga keputusan akhir untuk penerbitan dilakukan secara online.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 176 Documents
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PENGARUH TINGKAT PENDIDIKAN TERHADAP PENGETAHUAN PENGGUNAAN ANTASIDA DI DUSUN KEPEK BANTULPERIODE JANUARI 2022 Ajeng Eka Septyaningrum; Dwi Hastuti
FORTE JOURNAL Vol 2 No 2 (2022): Edisi Juli 2022
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i2.336

Abstract

Gastritis is an inflammation of the stomach wall. Based on data from the Bantul Health Office, the incidence of gastritis in 2020 was in the third position of the 10 largest diseases in the Bantul District Health Center with a total of 25,517 cases. One treatment that can be done is to use antacids. The purpose of this study was to determine the effect of education level on knowledge of antacid use in Kepek Village, Bantul for the period January 2022. This type of research is using analytical observational method with a cross sectional approach and data collection by giving questionnaires to the respondents. The sample used was 95 respondents. The research instrument used was a questionnaire sheet. Data analysis was done inferentially. The number of correct answers is calculated then calculates the percentage level of knowledge and is categorized based on good, enough and less. The effect of education level on knowledge of antacid use was tested using SPSS with Chi-Square test. The results of data processing show that the education level of the people of Dusun Kepek consists of elementary school (12.63%), junior high school (14.74%), high school (54.73%) and undergraduate (17.89%). Validation test was carried out on 18 questions and obtained valid results totaling 13 questions. Based on the Chi-Square Test, a significance value of 0.001 <0.05 Ha was accepted, meaning that there was an influence between education level on knowledge of antacid use in Kepek Village, Bantul.
HUBUNGAN KARAKTERISTIK PASIEN RAWAT JALAN TUBERKULOSIS PARU TERHADAP TINGKAT KEPATUHAN MINUM OBAT DI PUSKESMAS SAWIT SEBERANG Grace Anastasia br Ginting; Eva Diansari Marbun; Andre Prayoga; Rosmeri Br Karo
FORTE JOURNAL Vol 2 No 2 (2022): Edisi Juli 2022
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i2.348

Abstract

Pulmonary tuberculosis is an infectious disease, so non-adherence to treatment will result in treatment failure, risk of death, and cause more patients to become resistant. This study aims to determine the relationship between the characteristics of pulmonary tuberculosis outpatients on the level of medication adherence in Sawit Seberang Public Health Center. This research was conducted with a cross sectional survey research method. The instrument used in this study was a validated questionnaire containing 8 questions about patient compliance and pill count data by calculating the patient's remaining medication. A total of 45 patients were used as respondents who had pulmonary tuberculosis. Data were analyzed using the Statistical Package for the Social Sciences (SPSS) version 18 program. The results showed that the level of compliance of pulmonary tuberculosis patients in Sawit Seberang Public Health Center based on the questionnaire was high, namely 62.2%, and the compliance level of pulmonary tuberculosis patients in Sawit Seberang Public Health Center based on the Pill Count was perfect, namely 93.3%. Patient characteristics (gender, age, education, and occupation) did not affect the level of compliance of patients taking pulmonary tuberculosis drugs with p values of 0.462, 0.527, 0.260, 0.482 respectively. This study proves that the level of compliance of pulmonary tuberculosis patients in Sawit Seberang Public Health Center based on the questionnaire is high and based on the Pill Count is perfect.  Patient characteristics (gender, age, education, and occupation) did not affect the patient's level of compliance to taking pulmonary tuberculosis drugs.
POLA PENGOBATAN INFEKSI SALURAN PERNAFASAN AKUT (ISPA) PEDIATRIK RAWAT INAP DI PUSKESMAS SAWANG KABUPATEN ACEH UTARA Eva DIansari Marbun; Modesta Harmoni Br Tarigan; Erlita Utari
FORTE JOURNAL Vol 2 No 2 (2022): Edisi Juli 2022
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i2.351

Abstract

Acute Respiratory Infection (ARI) is a disease that is often experienced by toddlers with symptoms such as cough, runny nose and fever for the last 2 weeks. ARI can be caused by one of the factors, namely internal/environmental factors. The purpose of this study was to determine whether the treatment therapy for Pediatric ARI at the Sawang Health Center had met WHO standards or not. This study is a descriptive observational research method that aims to describe research problems that occur based on the characteristics of patients with pediatric ARI. This research was conducted from July-September 2020, while correspondent medical record data was taken in April-June 2020. while respondents who met the inclusion criteria were as many as 50 respondents. The results showed that of the 50 respondents who had ARI patients, the most experienced ARI based on gender were male (54%), and pediatric 4-7 years (56%). The class of antibiotics most often used in ARI therapy is the penicillin group (Amoxicilin) ​​(32%) compared to other groups, while additional symptomatic drugs to relieve symptoms caused by ARI that are often used are analgesic drugs (paracetamol) (100%). The results of the study based on statistical analysis tests obtained sig 0.005 results, it can be concluded that there is a significant relationship between all criteria (age, gender, use of antibiotic therapy drugs and use of symptomatic therapy drugs) and the pattern of ARI treatment at the Sawang Health Center, North Aceh Regency.
EVALUASI RASIONALITAS PENGGUNAAN ANTIBIOTIK ISPA PADA PASIEN RAWAT JALAN DI PUSKESMAS KECAMATAN GUNUNG SITOLI Artha Yuliana Sianipar; Grace Anastasia Ginting; Yosefin Hellen
FORTE JOURNAL Vol 2 No 2 (2022): Edisi Juli 2022
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i2.352

Abstract

URTI (Upper Respiratory Tract Infection) is a major disease in children in outpatient installation. Antibiotics are the most widely used class of drugs to treat infections. Antibiotics must be used rationally. Because the bad impact that occurs is the emergence of bacterial resistance. This study aims to obtain an overview of the rationality of the use of antibiotics in URTI patients, especially in children aged 5 to 11 years. The method used is a retrospective descriptive method, using medical record cards and prescription sheets for patients diagnosed with URTI and receiving antibiotics at the Gunungsitoli District Health Center during the period January to December 2020. Sampling used the purposive sampling method. Data that met the inclusion criteria were children aged 5-11 years and receiving antibiotic therapy. Then a table is made which includes the patient's identity, diagnosis, antibiotics, and the dose used. Then presented in the form of percentages, average values ​​and tables. The results showed that of the 64 patients who suffered the most URTI by age were patients aged 5 years (26.56%), the antibiotic group that was most often prescribed was the penicillin group, namely amoxicillin. (54.69%). Evaluation of rational use of antibiotics based on the 2011 Ministry of Health guidelines includes the right patient criteria (100%), right indication (100%), right frequency (100%), right drug (100%), right duration (98.44%), and right dose (93.75%).
EVALUASI PEMAKAIAN VITAMIN D3 1000 IU SELAMA PANDEMI COVID-19 DI RUMAH SAKIT TK-II PUTRI HIJAU MEDAN Modesta Harmoni Tarigan; Christica Ilsana; Sri Multerisnawati Lubis
FORTE JOURNAL Vol 2 No 2 (2022): Edisi Juli 2022
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i2.353

Abstract

Large variations in COVID-19 mortality rates between countries and regions have been reported. In addition to age, comorbid diseases, and availability of health facilities; Vitamin D3 adequacy status is assumed to play a role, considering that the COVID-19 mortality rate was found to be relatively higher in countries with a high incidence of vitamin D3 deficiency, such as Italy, Spain, and France. Vitamin D3 has been shown to lower the risk of respiratory tract infections. At the same time, its effect in enhancing cellular and adaptive immunity also makes vitamin D3 worthy of consideration as a potential option for treating and preventing COVID-19. Sick Tk-II Putri Hijau Medan. This study uses a descriptive research method with a cross sectional approach with a retrospective research design, namely research by reviewing information or taking past data (Sugiyono, 2018). The data was obtained from prescriptions for the period February-April 2021. The results showed that there was an increase in the use of Vitamin D3 1000 IU, especially in moderate Covid 19 patients, as well as an increase in the use of Vitamin C 1000 mg and Vitamin C 500 mg. This is done with the aim of increasing the body's resistance when infected with Covid 19. In severe Covid 19 patients, vitamins are no longer given but rather are given anti-virus and anti-biotic treatment in the form of injections.
GAMBARAN KEJADIAN EKSTRAPIRAMIDAL SINDROM PADA PASIEN TERAPI ANTIPSIKOTIK TIPIKAL DI RUMAH SAKIT JIWA ACEH Vivi Asfianti; Alfi Syahfitri; Zuhairiah NST
FORTE JOURNAL Vol 2 No 2 (2022): Edisi Juli 2022
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i2.367

Abstract

The use of antipsychotics in schizophrenic patients often causes side effects in the form of Extra Pyramidal Syndrome (EPS), namely the presence of uncontrolled muscle movement disorders such as seizures, shaking and so on. The incidence of EPS is more common with the use of typical antipsychotics than atypicals. This study aims to see the incidence of EPS in inpatients with schizophrenia at the Aceh Mental Hospital located in Banda Aceh in 2020. The population in this study were all inpatients who were given typical antipsychotics. While the research sample was 399 samples collected from medical record data of inpatients in 2020, so the study was retrospective with a cross sectional approach. Data collected in the form of patient identity (gender, age), drug therapy (typical antipsychotics) and the incidence of EPS. The results showed that schizophrenic patients who received typical antipsychotic therapy who were hospitalized at the Aceh mental hospital in 2020, were 324 men (81.2%) and 75 women (18.8%), with the highest age range being at 36-45 years amounting to 202 people (50.6%). Typical antipsychotic therapy used in the form of combination of typical-typical and typical-atypical drugs, namely clozapine-trifluperazine (40.6%), chlorpromazine-risperidone (20.3%), haloperidol-chlorpromazine-trifluperazine (16%), haloperidolchlorpromazine (7%), and haloperidol-trifluperazine (5%). The incidence of EPS that occurred was 113 people (28.3%), with the highest number of EPS occurring from the administration of haloperidol-chlorpromazine-trifluperazine combination antipsychotic therapy, which was 61 people (15.3%).
STUDI PELEPASAN TEOFILIN DARI CANGKANG KAPSUL ALGINAT-KITOSAN MENGGUNAKAN TRIPOLIFOSFAT SEBAGAI CROSSLINKER Cut Intan Annisa Puteri; Rahmadani Rahmadani; Chairunnisa Anggi
FORTE JOURNAL Vol 2 No 2 (2022): Edisi Juli 2022
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i2.372

Abstract

The modified formulation provides a fairly effective way to overcome the problem of bioavailability and results in increasing drug reactions and minimizing fluctuations in blood levels during release. The crosslinker in this study is sodium tripolyphosphate (Na-TPP) which is considered the best binding agent and can produce prolonged drug release. The purpose of this study was to determine the profile of theophylline release from the capsule shell of the alginate-chitosan matrix combination using the crosslink method. The capsule shell was made with the ratio of the percentage of alginate ; chitosan; The TPP are F1 (2%; 2%; 4%) and F2 (4%; 2%; 4%). The difference in percentage is intended to determine the ratio of the most optimal levels of releasing theophylline. The results obtained showed that theophylline capsules from formulas F1 and F2 could release the drug slowly and for a long time to the artificial intestinal fluid pH 7.4 for 8 hours for formula F1 and for 12 hours for formula F2 with a cumulative percentage of release of 99.75%.
FORMULASI DAN EVALUASI SEDIAAN HAIR TONIC EKSTRAK BUAH PARE (Momordica charantia L.) PADA PERTUMBUHAN RAMBUT KELINCI Reza Farhan; Muhammad Khatami; Hafiz Hafiz
FORTE JOURNAL Vol 2 No 2 (2022): Edisi Juli 2022
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i2.389

Abstract

This study aims to determine the content of flavonoid and saponin compounds in bitter melon which is very good as a hair stimulant. The research was conducted experimentally. Hair tonic preparations were made by adding bitter melon extract with various concentrations, namely 5g (F1), 10g (F2), 15g (F3) and as blank (F0). Tests on hair tonic preparations include organoleptic test, homogeneity test, pH test, irritation test and hair growth activity test. The hair tonic preparation is stable in storage and homogeneity, the pH of the preparation is (5.7-6.4) and there is no redness or swelling of the skin when using the preparation. The results of hair growth are 5.0mm (F1), 5.6mm (F2), 6.7mm (F3) and 4.3mm (F0). The results showed that the higher the concentration, the higher the level of hair growth activity and hair tonic with the addition of bitter melon fruit extract (Momordica charantia L.) with a concentration of 15% (F3) had the best activity in rabbit hair growth.
HUBUNGAN TINGKAT PENDIDIKAN TERHADAP PENGETAHUAN PENGGUNAAN ANALGETIK PADA MASYARAKAT DUSUN BANYUMENENG 2 GIRIHARJO PANGGANG GUNUNGKIDUL PERIODE JANUARI 2022 Dian Nur Afriyani; Dwi Hastuti
FORTE JOURNAL Vol 2 No 2 (2022): Edisi Juli 2022
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i2.391

Abstract

Based on the 2018 riskasdes, the prevalence of pain in Yogyakarta was 7,3%. Analgesic is one of the drugs that are often used for treatment with a percentage of 36,2-59%. Analgesic drugs can relieve pain such as menstrual pain, toothache, and headaches. Inappropriate use of analgesics in the community can cause adverse side in the long term. Sereval studies show that public knowedge is still lacking in the use of analgesics. The purpose of this study was to determine the relationship between aducation level and knowledge of analgesic use in community of Banyumeneng 2, Giriharjo, Panggang, Gunungkidul Period January 2022. The research method used is analytic observasional with a cross sectional approach. Data collection using purposive sampling technique using a knowledge questionnaire, the result abtained are processed and analyzed using SPSS 23 with Chi Square test. The number of subjects in the study were 88 respondents. This study shows that the result of the Chi-Square test obtained the Asymp value. Sig 0,000 is less than 0,05 which means Ha is accepted so it can be concluded that there is a relationship between education level and knowledge of analgesic use. The conclusion of this study is that there is a relationship between the level of education and knowledge of the use of analgesics.
MONITORING DAN EVALUASI CARA DISTRIBUSI ALAT KESEHATAN YANG BAIK (CDAKB) PADA PEDAGANG ALAT KESEHATAN PT.X DI KOTA BATAM Yan Yan; Mona Asiah; Ovalina Sylvia Br. Ginting
FORTE JOURNAL Vol 2 No 2 (2022): Edisi Juli 2022
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i2.392

Abstract

Distribution is an important aspect in ensuring the quality of the preparation. Medical Device Distributors must have adequate facilities and infrastructure to ensure the implementation of distribution, management, procurement, and storage. The purpose of this study was to determine Medical Device Distributors compliance with CDAKB requirements in the distribution of medical devices. This study uses the direct observation method on the research object to see the activities carried out and compare them with the CDAKB requirements listed in the Draft Technical Instructions for Supervision of Medical Device Distribution Facilities. Monitoring objects are documents, officers, facilities/infrastructure, and distribution activities. The results of the observations are the percentage of the level of fulfillment of the CDAKB requirements by dividing the total score achieved by the maximum number of scores and then multiplying by 100%. The results of the analysis of the level of CDAKB compliance show that PT. X meets 59 of 84 points (70.24%) requirements divided into 4 aspects, namely quality management system, resource management, product storage, and handling, and corrective actions, returns, and product destruction. In conclusion PT. X meets the CDAKB requirements and is in a good category.

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