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INDONESIA
Indonesian Journal of Innovation Studies
ISSN : -     EISSN : 25989936     DOI : https://doi.org/10.21070/ijins.v17i
Indonesian Journal of Innovation Studies (IJINS) is a peer-reviewed journal published by Universitas Muhammadiyah Sidoarjo four times a year. This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge.This journal aims is to provide a place for academics and practitioners to publish original research and review articles. The articles basically contains any topics concerning new innovation on all aspects. IJINS is available in online version. Language used in this journal is Indonesia or English.
Arjuna Subject : Umum - Umum
Articles 981 Documents
Identification of Genes in Positive Alleles Marking Type 2 Diabetes Mellitus Using Primer A18: Identifikasi Gen pada Alel Positif Penanda Diabetes Melitus Tipe 2 Menggunakan Primer A18 Firda, Aminatul; Mushlih, Miftahul
Indonesian Journal of Innovation Studies Vol. 15 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (225.807 KB) | DOI: 10.21070/ijins.v15i.549

Abstract

Diabetes mellitus type 2 (DMT2) is a disorder characterized by hyperglycemia due to impaired insulin secretion and insulin resistance. The purpose of this study was to identify the gene involved in the positive allele of DMT2 marker using A18 primer and is a type of exploratory descriptive study. The samples used were 2 samples of DMT2 patients from the villages of Taman and Balongbend, and 8 samples of DNA collection at the Molecular Biology Laboratory, Muhammadiyah University of Sidoarj. Based on the genetic analysis carried out, the GATB gene (Glutamyl-tRNA Amidotransferase Sub Unit B) was identified in the positive allele with a homology value of "percentage identity" between the sample sequence and the sequence data in the NCBI Genbank of 80 and 88%. This research hypothesizes that the GATB gene has a relationship with the emergence of DMT2 as evidenced by the relationship between the gene and the performance of mitochondria to produce ATP which is needed by pancreatic beta cells to produce insulin.
Identification of Genes in Positive Alleles Marking Type II Diabetes Mellitus Using Primer D20: Identifikasi Gen pada Alel Positif Penanda Diabetes Melitus Tipe II Menggunakan Primer D20 Kartikasari, Erina Wahyu; Mushlih, Miftahul
Indonesian Journal of Innovation Studies Vol. 15 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (225.922 KB) | DOI: 10.21070/ijins.v15i.550

Abstract

Diabetes Mellitus is a metabolic disorder disease characterized by an increase in blood glucose due to insulin resistance (impaired insulin function) and or a decrease in insulin secretion. Genetically, Type 2 Diabetes Mellitus is influenced by genes that affect glucose metabolism in the body. The purpose of this study was to identify the genes involved in type 2 diabetes mellitus patients who were amplified using D20 primers. The method used in this research is descriptive experimental using 2 whole blood samples and 8 samples collected from DNA isolation in the Molecular Biology Laboratory of Type 2 Diabetes Mellitus patients. The results of the research based on the BLAST program obtained matched gene sequences from the sequenced leucine rich repeats gene. and guanylate kinase domain containing (LRGUK). The LRGUK gene is thought to be associated with Type 2 Diabetes Mellitus because the presence of SNP (Single Nucleotide Polymorphism) in the area around the LRGUK gene (7q32) shows a significant relationship with fasting blood glucose.
Comparison of the Quality of DNA Template Isolation Results of the Resin Method with and Without Centrifugation: Perbandingan Kualitas DNA Template Hasil Isolasi Metode Resin dengan dan Tanpa Sentrifugasi Jayanti, Liah Dwi; Mushlih, Miftahul
Indonesian Journal of Innovation Studies Vol. 15 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (231.99 KB) | DOI: 10.21070/ijins.v15i.551

Abstract

The centrifugation process is able to separate the blood into several components, including the buffy coat. Buffy coat contains white blood cells that have a cell nucleus which is the source of DNA. This research uses descriptive experimental method. The samples used were 16 venous blood samples consisting of 8 samples without centrifugation (wholeblood) and 8 samples centrifuged (buffycoat). DNA isolation using the resin method. Quantitative analysis was performed using a UV-Vis spectrometer. The results showed that the average concentration and purity of DNA in the centrifuged sample was higher than in the sample without centrifugation. The result of this research is that the centrifuged sample (buffycoat) can be used for the DNA isolation process and has a higher purity and concentration value than the sample without centrifugation (wholeblood).
Comparison the Quality of Template DNA isolated by Column Method with and without Centrifugation: Perbandingan Kualitas DNA Template yang diisolasi dengan Metode Kolom dengan dan tanpa Sentrifugasi Wardana, Aji Cakra; Mushlih, Miftahul
Indonesian Journal of Innovation Studies Vol. 15 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (214.129 KB) | DOI: 10.21070/ijins.v15i.552

Abstract

DNA isolation is the first step in molecular biology work. The quality of the DNA template is very important because it can affect the DNA amplification reaction. The application of centrifugation to the sample is expected to produce a Buffy coat layer containing nuclear cells. This study aims to compare the quality of the DNA template isolated from the column with and without centrifugation. This research used descriptive experimental method. The samples used were 16 samples with the division of 8 samples given centrifugation treatment and 8 samples without centrifugation. DNA isolation column method is a DNA isolation method that uses a silica membrane, where the silica membrane works as a filter for DNA that is split from the cell. The DNA isolation method column was carried out according to the standard protocol on the Geneaid DNA mini Kit Blood/Tissue. The concentration and purity of DNA were measured using UV-Vis Spectrophotometry at 260 nm and 280 nm. Visualization of DNA isolation results was carried out using 1% agarose gel. The results of measuring the quality of DNA samples using the column method with centrifugation showed better results with clearer visualization of DNA bands than samples without centrifugation. The results of the T dependent statistical test on both samples of p value < 0.05 showed that there was a significant difference in DNA quality with centrifuged and non-centrifuged treatment.
Differences in DNA Purity Test Using UV-Vis Spectrophotometer and Nanodrop Spectrophotometer in Type 2 Diabetes Mellitus Patients: Perbedaan Uji Kemurnian DNA Menggunakan Spektrofotometer UV-Vis dan Spektrofotometer Nanodrop pada Pasien Diabetes Melitus Tipe 2 Dewanata, Pandu Aji; Mushlih, Miftahul
Indonesian Journal of Innovation Studies Vol. 15 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (214.128 KB) | DOI: 10.21070/ijins.v15i.553

Abstract

DNA quality test is one of the basic techniques in Molecular Biology which aims to determine the presence or absence of protein and RNA contamination. DNA quantity test can be done using a spectrophotometer. Spectrophotometer is a tool used to measure the concentration of a compound based on its ability to absorb light. The purpose of this study was to determine differences in DNA purity as measured by UV-Vis Spectrophotometer and Nanodrop Spectrophotometer. The method used in this research is descriptive exploratory with purposive sampling technique. The number of samples used is 15 samples. The results of this study are that there are differences in the concentration and purity of DNA from quantitative tests with UV-Vis spectrophotometers and Nanodrops obtained based on statistical tests using the T Dependent Test. The result of this research is that in measuring DNA purity there is a difference in DNA purity because the results of Sig (2-Tailed) use 0.001 or below 0.05 (Ha is accepted). And based on statistical tests on DNA concentration measurements, it is known that there are differences in DNA concentrations.
Improving School Image and Parents' Interest in Choosing Schools Influenced by Product, Promotion and Pricing Strategies in Elementary Schools: Peningkatan Citra Sekolah Serta Minat Orang Tua Siswa Untuk Memilih Sekolah yang Dipengaruhi oleh Strategi Produk, Promosi dan Harga Pada Sekolah Dasar Sulchan, Kusnaini; Rizal, Hadiah Fitriyah
Indonesian Journal of Innovation Studies Vol. 15 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3276.858 KB) | DOI: 10.21070/ijins.v15i.554

Abstract

The purpose of this thesis research is to find out and analyze the product, promotion and price affect the school's image, influence the parents' interest in choosing the school and to find out and analyze the school image as a mediator variable capable of influencing the relationship between product, promotion, price and parents' interest in choosing a school. schools at SD Muhammadiyah 5 Porong. This research belongs to the type of quantitative research and uses descriptive statistical analysis. Researching on a particular population or sample. Data collection with a limited questionnaire method. Respondents are the guardians of the students of SD Muhammadiyah 5 Porong as many as 125 people. Validity test analysis. It is necessary to test the validity and reliability of the researcher's information using the W-Start program. .Analysis of hypothesis testing on the relationship between variables should be carried out using path analysis assisted by the SPSS type 21 windows program. The results of the SPSS program analysis show that the influence of the Product, Promotion and Price aspects together in producing School Image is 65%. Meanwhile, the other 35% of m is influenced by other aspects.
Analysis of the Implementation of Musyarakah Financing Based on the Standard Book of Musyarakah Products: Analisis Implementasi Pembiayaan Musyarakah Berdasarkan Buku Standar Produk Musyarakah Badruzzaman, Azzam; Latifah, Fitri Nur
Indonesian Journal of Innovation Studies Vol. 15 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (214.104 KB) | DOI: 10.21070/ijins.v15i.555

Abstract

The musyarakah financing product is a competitive flagship product of Sharia Rural Banks (BPRS) which has not experienced growth like other financing products. The lack of development of musyarakah financing products has caused BPRS to have more products based on fixed income financing which is similar to the conventional pattern that uses a fixed income structure. PT. BPRS Baktimakmur Indah is the largest BPRS with assets of Rp. 163,147,899,000 and the financing provided to the community reaches Rp. 126,807,530 as of December 31, 2019. This research was conducted at BPRS Baktimakmur Indah Branch throughout Sidoarjo which is located at Jln. Raya Bebekan No.21 Throughout the Taman District, Sidoarjo Regency. The purpose of this study was to analyze the implementation of musyarakah financing based on the standard book of musyarakah products published by the financial services authority. By using qualitative research methods through a phenomenological paradigm approach that requires researching a natural setting, with observation data collection techniques, direct interviews and literature from companies to support data needs. After the research was carried out, it was found that the BPRS Baktimakmur Indah branch of the Panjang branch had implemented musyarakah financing in accordance with the standard book of musyarakah products issued by the financial services authority.
The Effect of Experiential Marketing and Brand Image on Purchase Decisions Through Word of Mouth as Intervening Variables: Pengaruh Experiential Marketing Dan Brand Image Terhadap Purchase Decision Melalui Word Of Mouth Sebagai Variabel Intervening Fatchiyah, Alifatul; Sukmono, Rita Ambarwati
Indonesian Journal of Innovation Studies Vol. 16 (2021): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (208.098 KB) | DOI: 10.21070/ijins.v16i.556

Abstract

This study aims to determine the effect of Experiential Marketing (X1) and Brand Image (X2) variables on Purchase Decision (Y) through Word Of Mouth (Z) as Intervening Variables. This research was conducted at LKP Modes Aniq Sidoarjo. This study uses a survey method where the primary data is obtained from a questionnaire. The sample is a resident of Modes Aniq who is taken randomly as many as 100 respondents. Data analysis method using PLS (Partial Least Square) using smart PLS software version 3.0. The results showed that Experiential Marketing had a positive and significant effect on Purchase Decision. Experiential Marketing has a positive and significant effect on Word Of Mouth. Brand Image has a positive and significant effect on Purchase Decision. Brand Image has a positive and significant effect on Word Of Mouth. Word of Mouth has a positive and significant effect on Purchase Decision. Experiential Marketing indirectly has a positive and significant effect on Purchase Decision through Word Of Mouth as an Intervening variable. Brand Image indirectly has a positive and significant effect on Purchase Decision through Word Of Mouth as an Intervening variable. Keywords: Experiential Marketing, Brand Image, Word Of Mouth and Purchase Decision.
The Effect of Tax Planning, Deferred Tax Expense, Leverage, and Financial Distress on Earnings Management in Manufacturing Companies in the Consumer Goods Industry Sector Listed on the IDX in 2014-2018: Pengaruh Tax Planning, Beban Pajak Tangguhan, Leverage, Dan Financial Distress Terhadap Manajemen Laba Pada Perusahaan Manufaktur Sektor Industri Barang Konsumsi Yang Terdaftar Di BEI Tahun 2014-2018 Andayani, Fatma Dwi; Setiyono, Wisnu Panggah
Indonesian Journal of Innovation Studies Vol. 16 (2021): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (208.098 KB) | DOI: 10.21070/ijins.v16i.557

Abstract

This study aims to examine the effect of tax planning, deferred tax burden, leverage, and financial distress on earnings management. The approach used in this study is a quantitative approach with a sampling technique using purposive sampling method. The sample in the study was 10 manufacturing companies in the consumer goods industry sector listed on the IDX in 2014-2018. The analytical technique used in this study is panel data regression analysis with the help of the Eviews9 program. The results of this study indicate that the tax planning variable has no effect on earnings management, deferred tax expense has a negative effect on earnings management, leverage has a positive effect on earnings management, financial distress has no effect on earnings management and simultaneously tax planning, deferred tax expense, leverage, financial distress has no effect on management.
The Effect of Liquidity and Profitability on Stock Prices With Dividend Policy as Moderation in Manufacturing Companies Listed on the Stock Exchange in 2016-2018: Pengaruh Likuiditas Dan Profitabilitas Terhadap Harga Saham Dengan Kebijakan Dividen Sebagai Moderasi Pada Perusahaan Manufaktur Yang Terdaftar Di Bei Pada Tahun 2016-2018 Mardianti, Any; Dewi, Santi Rahma
Indonesian Journal of Innovation Studies Vol. 16 (2021): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4032.865 KB) | DOI: 10.21070/ijins.v16i.558

Abstract

This study aims to determine the effect of liquidity, and profitability on stock prices with dividend policy as a moderating variable on the Indonesia Stock Exchange in 2016 – 2018. The method used is purposive sampling and produces 38 sample companies, so the total research data is 114 data. Hypothesis testing is done by using multiple linear regression analysis and regression analysis. The results show that liquidity has a significant positive effect on stock prices, profitability has a significant positive effect on stock prices, dividend policy has a significant positive effect on stock prices. Dividend policy weakens the relationship between liquidity and firm value. Dividend policy strengthens the relationship between profitability and firm value. The results of the coefficient of determination test show that the independent variable, moderating variable and the interaction of the two variables are only able to explain the dependent variable by 22.9%, while the remaining 78.1% is explained by other variables not explained in this study.

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