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Contact Name
Dharma Lindarto
Contact Email
jetromi@usu.ac.id
Phone
+6282168842564
Journal Mail Official
jetromi@usu.ac.id
Editorial Address
Jalan Dr T Mansur No 9 Padang Bulan, Kecamatan Medan Baru, Kota Medan, Sumatera Utara, Indonesia
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Unknown,
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INDONESIA
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Published by TALENTA PUBLISHER
ISSN : 26860872     EISSN : 26860856     DOI : 10.32734
Core Subject : Health, Science,
Journal of Endocrinology, Tropical Medicine and Infectious Diseases (JETROMI) is an international peer-reviewed journal (February, May, August and November) published by TALENTA Publisher, Universitas Sumatera Utara and managed by Faculty of Medicine, Universitas Sumatera Utara. It is dedicated to interchange for the articles of high quality research in the field of Medical Science. The journal publishes state-of-art papers in fundamental theory, case report, experiments and simulation, as well as applications, with a systematic proposed method, sufficient review on previous works, expanded discussion and concise conclusion. As our commitment to the advancement of science and technology, the JETROMI follows the open access policy that allows the published articles freely available online without any subscription. Each publication contains 6 (six) research articles which will be published online.
Articles 151 Documents
ASSOCIATION BETWEEN HbA1c WITH PLATELET TO LYMPHOCYTE RATIO AND NEUTROPHIL TO LYMPHOCYTE RATIO IN TYPE 2 DIABETES MELLITUS Villarsi, Devinda; Brama Ihsan Sazli; Pase, M Aron
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 8 No. 1 (2026): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v8i1.23024

Abstract

Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease in which inflammation plays a significant role in both microvascular and macrovascular complications. The Neutrophil-to-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) are simple hematological biomarkers that can reflect systemic inflammatory status and potentially correlate with HbA1c levels as an indicator of glycemic control. Objective: To determine the association between HbA1c levels and NLR and PLR in T2DM patients at Haji Adam Malik General Hospital, Medan. Methods: This was a retrospective cross-sectional study using secondary data from the medical records of T2DM patients between May and July 2024. A total of 96 patients met the inclusion criteria. Data were analyzed using the Kruskal-Wallis test with a significance level of p<0.05. Results: The median HbA1c of the patients was 9% (range 4.2–15.4%). Median NLR increased according to HbA1c categories: 3.91 (HbA1c <7%), 5.77 (HbA1c 7–9%), and 7.19 (HbA1c >9%) with p=0.012. Median PLR also increased across categories: 134.75, 189.00, and 233.33 with p=0.009. Conclusion: A significant association was observed between HbA1c and both NLR (p = 0.012) and PLR (p = 0.009). NLR and PLR can be used as additional hematological parameters to assess inflammation and glycemic control in patients with type 2 diabetes.

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