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Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Published by TALENTA PUBLISHER
ISSN : 26860872     EISSN : 26860856     DOI : 10.32734
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Journal of Endocrinology, Tropical Medicine and Infectious Diseases (JETROMI) is an international peer-reviewed journal (February, May, August and November) published by TALENTA Publisher, Universitas Sumatera Utara and managed by Faculty of Medicine, Universitas Sumatera Utara. It is dedicated to interchange for the articles of high quality research in the field of Medical Science. The journal publishes state-of-art papers in fundamental theory, case report, experiments and simulation, as well as applications, with a systematic proposed method, sufficient review on previous works, expanded discussion and concise conclusion. As our commitment to the advancement of science and technology, the JETROMI follows the open access policy that allows the published articles freely available online without any subscription. Each publication contains 6 (six) research articles which will be published online.
Arjuna Subject : Kedokteran - Endokrinologi, Diabetes dan Metabolisme
Articles 151 Documents
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Troponin I and Major Adverse Cardiovascular Events in Acute Coronary Syndrome : Are They Related? Jessi Vania Tambarta; Aryfa Andra , Cut; Rohmawati, Lili; Atiyatul Amra, Aryani
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 2 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i2.19156

Abstract

Background : Coronary Artery Disease (CAD) is one of the leading cause of death globally. The most threatening manifestation of CAD is Acute Coronary Syndrome (ACS), that classified as Unstable Angina Pectoris (UAP), Non ST Elevation Myocardial Infarction (NSTEMI) and ST Elevation Myocardial Infarction (STEMI). ACS patients tend to have complication, that usually defined as Major Adverse Cardiovascular Events (MACE) which  consists of heart failure, arrhythmia, stroke, and in-hospital mortality. Some factors have been researched to predict MACE in ACS, such as troponin level, which has been one of the modality to diagnose ACS. This study aims to determine the association between cTnI level and MACE in ACS patients at Adam Malik General Hospital. Method : This study used an observational analytic method with cross sectional design and retrospective approach. The data used is a secondary data that meets the inclusion and exclusion criteria. Result : Among 190 patients, 170 patients (89,5%) were >45 years old and 114 patients (75,8%) were male. The most common type of ACS was NSTEMI, with 73 patients (38,4%). cTnI level was increased in 131 patients (68,9%). There were 115 patients (60,5%) who experienced MACE and were dominated by heart failure, with 78 patients (41,1%). There was an association found between troponin level and MACE  (p=0,000). Conclusion : There was an association  between troponin level and MACE in ACS patients.
The Association Between Stress Hyperglycemia Ratio (SHR) and Cardiovascular Event in Acute Coronary Syndrome Patients at Adam Malik Hospital Siregar, Anisafitri; Nasution, Melati Silvanni; Sazli, Brama Ihsan
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 2 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i2.19443

Abstract

Introduction: Acute hyperglycemia in patients with acute coronary syndrome (ACS) has been associated with major adverse cardiovascular events (MACE). The stress hyperglycemia ratio (SHR) is considered a potential marker for predicting MACE in ACS patients. This study aims to evaluate the relationship between SHR and MACE among ACS patients at Adam Malik Hospital, Medan. Methods: This study employed a retrospective analytic design by collecting data from the medical records of ACS patients treated at Adam Malik Hospital, Medan, during 2022–2023. Inclusion criteria included: confirmed ACS patients (who underwent coronary angiography), while exclusion criteria were: patients with an E-GFR <30 ml/min and those with malignancies, liver diseases, hematological disorders, or infections (sepsis). The chi-square test was used to evaluate the relationship between variables, with a p-value <0.05 considered statistically significant. Results: A total of 100 ACS patients met the study criteria, with an average age of 59 ± 10.3 years, and 78% were male. The mean SHR among the study subjects was 1.09 ± 0.36. MACE was recorded in 64% of patients, including heart failure in 44%, rehospitalization in 12%, stroke in 9%, and mortality in 31%. SHR was found to have a significant relationship with overall MACE (p <0.001) and heart failure events (p = 0.001). However, no association was found between SHR and stroke, rehospitalization, mortality, or 3-point MACE (p >0.05). Conclusion: SHR has a significant relationship with MACE but not with 3-point MACE.
Periodontal Status in Periodontitis Patients with Type 2 Diabetes Mellitus at Tiga Dolok Health Center Amalia, Martina; Siagian, Jesika Gihon Aprelia; Aritonang, Okie Anggie Jelita
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 3 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i3.18393

Abstract

Background: Periodontitis is an inflammation of the periodontal tissue characterized by loss of attachment and the formation of periodontal pockets. Periodontitis impairs the metabolic control of patients with diabetes mellitus by increasing inflammation and insulin resistance, according to researchers. This study aims to determine the periodontal status and level of gingival inflammation in patients with periodontitis and type 2 diabetes mellitus at the Tiga Dolok Health Center. Method: This research is a descriptive study with a cross-sectional research design. The study's population and sample are patients with type 2 diabetes mellitus accompanied by periodontitis who visit the Tiga Dolok Health Center and meet the established inclusion and exclusion criteria, with a total sample size of 42 samples taken. Results: The research findings indicate that the average pocket depth is 4.052 mm, the average clinical attachment loss is 5.200 mm, and the level of gingival inflammation based on the gingival index shows that 18 individuals (42.9%) fall into the mild category and 24 individuals (57.1%) fall into the moderate category. Additionally, the papillary bleeding index shows that 31 individuals (73.8%) are in the >1 category, and 11 individuals (26.2%) are in the ≤1 category. Conclusion: As you can see, the periodontal health is moderate. The pocket depth is 4.052 ± 0.402 mm, the clinical attachment loss is 5.200 ± 0.822 mm, and the gingival index shows moderate gingival inflammation. In contrast, the papillary bleeding index falls into the category of >1.
The Impact of Local Wisdom Education 'Poda Na Lima' on Community Knowledge in Dengue Infection Prevention Daulay, Majidah Andilaila; Saragih, Rina Amalia Caromina; Rina Amelia; Pasaribu, Ayodhia Pitaloka; Fithri Hervianti; Veralia
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 3 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i3.20308

Abstract

Background. Dengue remains an endemic disease in almost all countries worldwide, including Indonesia. One approach to its prevention and control is community empowerment through education. Education is most impactful when aligned with the culture and local wisdom of the target community. Poda na lima is a form of local wisdom practiced by the Batak Angkola-Mandailing tribe in North Sumatra Province, Indonesia. This study aims to analyze the effect of poda na lima-based education on community knowledge regarding dengue prevention. Methods. Quasi-experiment with one group pretest-posttest. This study involved 68 respondents from the community in the working area of Puskesmas Sihepeng, Mandailing Natal Regency, through cluster random sampling with inclusion criteria in October – November 2024. Data were collected using questionnaires before and after the dengue education intervention with poda na lima and analyzed using the Wilcoxon signed rank test with the SPSS software. Result. Most of the respondents were in the age range of 19 – 45 years (80.9%), with a female gender (100%) and an education level of high school graduate (39.7%). There was an increase in the average knowledge before and after dengue education with the poda na lima, with statistically significant results (p<0.05) and an effect size > 0.5, meaning that the dengue education with the poda na lima has a large effect on the improve in knowledge. Conclusion. Dengue education with local wisdom poda na lima has a significant and large effect on improving community knowledge.
RELATIONSHIP BETWEEN C-REACTIVE PROTEIN AND IL-6 LEVELS AND EJECTION FRACTION IN HEART FAILURE PATIENTS AT ADAM MALIK HOSPITAL Pratiwi, Harvinda Arya; Refli Hasan; Lubis, Masrul; Mardianto
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 3 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i3.20467

Abstract

Background: Heart failure (HF) is a progressive condition markedby anatomical and functional cardiac defects. Inflammation is amajor factor in HF development. While some research implies a linkbetween elevated CRP and IL-6 levels and lower ejection fraction(EF), the results are inconsistent. This study aims to evaluate therelationship between C-reactive protein, IL-6 levels, and EF in heartfailure patients.Method: This cross-sectional analytic observational study wasconducted at Adam Malik Hospital to assess the relationshipbetween CRP and IL-6 levels and left ventricular EF (LVEF) in HFpatients. Result: The findings showed no significant connection betweenCRP and LVEF (p=0.391), implying that CRP does not directlyreflect systolic dysfunction. Conversely, IL-6 levels have asubstantial inverse connection with LVEF (p=0.001), indicating agreater link between systemic inflammation and cardiacperformance. Conclusion: These findings underline the importance of amultimodal approach to HF care, including the use of inflammatorymarkers for risk classification in this population. While CRP maynot be as accurate a predictor of systolic dysfunction, IL-6 appearsto be more closely related to heart failure severity. Keywords: CRP, Ejection fraction, Heart failure, IL-6.
Risk Factors of Type 2 Diabetes Mellitus in Pulmonary Tuberculosis Patients at Prof. Dr. Chairuddin P. Lubis Hospital USU Neny Pristiwati Harahap; R Lia Kusumawati; Noni Novisari Soeroso; Santi Syafril; Gema Nazri Yanni
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 3 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i3.20809

Abstract

Background: Diabetes mellitus (DM) and tuberculosis (TB) are major global health concerns with a bidirectional relationship that exacerbates clinical outcomes. Indonesia faces a high prevalence of both diseases; however, specific risk factors contributing to the incidence of Type 2 DM (T2DM) among pulmonary TB patients remain underexplored, particularly in North Sumatra. This study aims to identify risk factors associated with T2DMin patients with pulmonary TB. Method: A retrospective case-control study was conducted involving 80 participants, comprising 40 pulmonary TB patients with T2DM and 40 without DM. Data were obtained from electronic medical records and analyzed using Chi-square tests, Fisher’s Exact Test, and multivariate logistic regression. Result Educational level (OR = 5.001; p = 0.027), occupational status (OR = 3.500; p = 0.038), and nutritional status based on body mass index (OR = 3.498; p = 0.017) were significantly associated with the incidence of T2DM in pulmonary TB patients. Result: No significant associations were found for age, gender, radiographic findings, or smoking habits. Higher educational level, employment in the private sector, and having a normal to overweight BMI are key risk factors for T2DM among pulmonary TB patients.
Incidence of Bleeding Complications in Acute ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention Ferhat, Muhammad; Lubis, Anggia Chairuddin; Safri, Zainal; Mukhtar, Zulfikri; Hasan, Harris; Haykal, Teuku Bob; Siregar, Yasmine Fitrina; Andra, Cut Aryfa
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 3 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i3.21143

Abstract

Background: This study aims to comprehensively describe the incidence, types, and associated risk factors of bleeding complications in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI), addressing a critical gap in the literature given the global burden of cardiovascular disease and the inherent bleeding risks of contemporary antithrombotic therapies. Methode: This retrospective cross-sectional study will investigate the incidence and types of bleeding complications, along with associated risk factors, in ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI) at Adam Malik Hospital Medan, analyzing data from May 2022 to December 2024 through ethical review and statistical analysis using SPSS version 23. Result: Of 245 STEMI patients undergoing primary PCI, 42.9% experienced bleeding, predominantly minor (BARC 1 and 2, 94.2% combined), with significant associations observed between bleeding and lower hemoglobin, higher leukocyte and creatinine levels, higher TIMI score, Killip class 3 and 4, diabetes, use of maintenance heparin, and increased mortality (84.6% of all deaths occurred in bleeding patients), while hematuria and puncture site hematoma were the most common bleeding sources. Conclusion: This study found that 42.9% of 245 STEMI patients undergoing primary PCI experienced bleeding complications, predominantly minor (94.2%), with an average age of 55.22 years and a male majority. Keyword: Bleeding complications, Acute Coronary Syndrome (ACS), ST-Elevation Myocardial Infarction (STEMI), Primary Percutaneous Coronary Intervention (PPCI)
The Association Between The International Society On Thrombosis And Haemostasis- Disseminated Intravascular Coagulation Score And Early Mortality Of Acute Leukemia Patients tantri, Anita; Dairion Gatot; Lubis, Heny Syahrini; Mardia, Andri Iskandar
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 3 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i3.21198

Abstract

Background: Disseminated Intravascular Coagulation (DIC) is a serious complication frequently found in patients with acute leukemia and is associated with increased early mortality. The ISTH-DIC score is widely used to assess the severity of DIC. However, data on the association between ISTH-DIC score and early mortality in acute leukemia patients in Indonesia remains limited. Objective: To evaluate the association between ISTH-DIC score and early mortality (≤60 days) in acute leukemia patients at H. Adam Malik General Hospital, Medan. Methods: This was a retrospective cohort study involving 68 adult patients diagnosed with acute leukemia admitted from January 2022 to June 2024. Medical records were reviewed to collect laboratory parameters (platelet count, prothrombin time [PT], fibrinogen, and D-dimer) to calculate the ISTH score. Statistical analysis was performed using bivariate and multivariate logistic regression. Results: The early mortality rate was 58.8%. A substantial proportion of patients had ISTH-DIC scores ≥5, but no statistically significant association was found between ISTH score and early mortality (p = 0.704). However, PT >1.2 seconds was significantly associated with early mortality (p < 0.001; OR 18.00). Platelet count, D-dimer, and fibrinogen levels showed no significant association. Conclusion: The ISTH-DIC score was not significantly associated with early mortality in acute leukemia patients, but individual components such as prolonged PT showed a strong correlation. Early coagulation assessment remains essential in identifying patients at risk of life-threatening complications.
Analysis of Differences in Germ Patterns in Pus Culture and Tissue Culture Examination in Patients with Diabetic Foot Ulcers at H. Adam Malik General Hospital, Medan Harahap, Roni Ananda Perwira; Ginting, Franciscus; Sihotang, Lenni Evalena
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 4 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i4.20207

Abstract

Background: Diabetic foot ulcer (DFU) is one of the chronic complications of diabetes mellitus that can increase the risk of amputation and lead to high treatment costs if the infection is not properly managed. Identifying the etiology of the infection is crucial for determining effective treatment. However, in Indonesia, particularly at H. Adam Malik General Hospital in Medan, there has been no clear study focusing on identifying diabetic foot infection patterns based on tissue culture. The Infectious Diseases Society of America (IDSA) 2023 recommends using tissue culture techniques for bacterial identification, moving away from pus cultures. Objective: This study aims to analyze the differences in infection patterns obtained through pus culture and tissue culture in patients with diabetic foot ulcers. Methods: This prospective descriptive study involved 41 patients treated at H. Adam Malik General Hospital, Medan. Ulcer samples were collected using two methods: sterile swabs for pus culture and tissue samples for tissue culture. The culture results were analyzed using the Kruskal-Wallis statistical test to compare the differences in bacterial patterns. Results: Gram-negative bacteria dominated both culture methods, with Pseudomonas spp being the most common in pus cultures and Escherichia coli in tissue cultures. A significant difference was found between the two methods in bacterial identification (p < 0.05).Conclusion: There is a significant difference between tissue culture and pus culture in diabetic foot ulcers, particularly in the number and types of bacterial isolates, with a p-value of 0.002. This difference is not coincidental, supporting IDSA’s recommendation to prioritize tissue culture over swab culture. These findings are consistent with other studies in the field.
Comparison of Rapid Typhidot Test Based on Sanitation Environment in Healthy Individuals in Medan Robby Awaluddin Perangin-Angin; Rina Amelia; Jelita Siregar
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 6 No. 4 (2024): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v6i4.15365

Abstract

Typhoid fever is a gastrointestinal tract infectious disease frequently found endemic in Indonesia, which can be transmitted by oro-fecal from food or water contaminated directly or vector carries these bacteria. Medan Belawan subdistrict has a high rate of diarrhea cases and a low percentage of a health-house model. Otherwise, the Medan Petisah subdistrict has fewer diarrhea cases and a high percentage of the health-house model. This study was aimed to compare the presence of antibodies from the Typhidot Test in people living in poor and healthy sanitation conditions. This study is an observational study with a cross-sectional design. The population is all people around Medan Petisah and Medan Belawan health center. All data were calculated using SPSS and analyzed with Chi-Square and Regression Logistics tests. The result indicates no significant association between the presence of IgM and IgG from the results of the Typhidot test on environmental sanitation in Medan (p>0.05). Thus, it can be concluded that Sanitation conditions did not affect the formation of IgM and IgG against Salmonella Typhi bacteria.

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