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Jurnal Farmanesia
Published by Universitas Sari Mutiara Indonesia
ISSN : """"     EISSN : 25282484     DOI : https://doi.org/10.51544/jf.v8i2
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmanesia dengan E-ISSN: 2528-2484 merupakan jurnal resmi yang diterbitkan oleh Program Studi S1 Farmasi Fakultas Farmasi dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia, yang artikelnya dapat diakses dan diunduh secara online oleh publik (open access journal). Jurnal ini merupakan jurnal peer-review yang diterbitkan dua kali setahun dengan topik keunggulan hasil penelitian di bidang pelayanan dan praktik kefarmasian, teknologi farmasi, dan disiplin ilmu kesehatan yang berkaitan erat. Jurnal ini menerima teks bahasa Indonesia. Berikut ini adalah area penelitian yang menjadi fokus jurnal ini: 1. Farmakologi 2. Farmasetika 3. Biologi Farmasi 4. Kimia Farmasi 5. Farmakognosi 6. Fitokimia
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 18 Documents
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Search results for , issue "Vol 6 No 1 (2019): Jurnal Farmanesia" : 18 Documents clear
PENENTUAN KADAR BESI DI DALAM AIR SUMUR GALI PENDUDUK DI DESA KAMPUNG LALANG SECARA SPEKTROFOTOMETRI SINAR TAMPAK Thaib, Cut Masyithah; Sinaga, Eka Margaret; Purba, Dina Riani
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2743

Abstract

Water is one of the sources of iron compound contaminants and the iron content in dug well water used as a water source is influenced by location and environment. The purpose of this study was to determine the iron content in dug well water used in daily life in the village of Kampung Lalang. Samples were taken from five different dug wells. Determination of iron content was carried out according to the spectrophotometric method in accordance with the procedures and spectrophotometers used in the chemical laboratory of the University of Sari Mutiara Indonesia. The results showed that of the 5 samples tested there were 2 samples containing iron compounds exceeding the levels of iron compounds set by the Ministry of Health of the Republic of Indonesia Number 907/MENKES/SK/VII/2002, the permissible levels of iron compounds, which should not be more than 0.3 mg/day. l. The iron content of 5 wells ranged from 0.2457 - 0.405 mg/l.
PENERAPAN METODE SPEKTROFOTOMETRI SERAPAN ATOM (SSA) DALAM MENGANALISIS LOGAM MERKURI (Hg) PADA KRIM PEMUTIH WAJAH Nurbaya, Siti; Safwan, Ahmad Gazali; Silitonga, Maringan
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2744

Abstract

Whitening cream is a mixture of chemicals and or other ingredients with properties that can fade dark spots on the skin. Whitening cream must be safe and must not contain harmful ingredients such as heavy metal mercury because its toxicity to the organs of the kidneys, nerves, and brain is very strong, so its use is prohibited in cosmetic preparations. The purpose of this study was to determine the levels of metallic mercury (Hg) contained in the preparation of facial whitening creams circulating in Sei Sikambing Market, Medan. The sample used in this study was a facial whitening cream that was not registered with BPOM. The method used to determine mercury levels is qualitatively using color reagents and quantitatively using AAS (Atomic Absorption Spectrophotometry). The results obtained were from 2 samples of facial whitening cream that were used positively for heavy metal mercury (Hg) characterized by the formation of a red-orange precipitate with KI reagent, yellow precipitate by NaOH reagent, white precipitate by HCl reagent. The results of the analysis showed that the highest Hg metal content in the sample with code E was 5.0241 ± 0.4064 g/g. The conclusion of this study is that two samples were positive for mercury, where the use of mercury has been prohibited by BPOM.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN SAMBUNG NYAWA (Gynura procumbens (Lour.)Merr.) TERHADAP BAKTERI Bacillus cereus ATCC 6633 Thaib, Cut Masyithah; Zuhairiah, Zuhairiah; Sianipar, Artha Yuliana; Simanullang, Eta M. Br
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2745

Abstract

Life-sustaining plants are plants that are widely used by people as natural medicines. Infectious disease is one of the problems in the health sector. Infection can be caused by various microorganisms, one of which is bacteria. This research was conducted at the Microbiology Laboratory, Sari Mutiara University, Indonesia. This study was conducted to examine the antibacterial activity of the ethanolic extract of life-sustaining leaves using the paper disc diffusion method with concentration variants of 20%, 30%, 40%, 50%, and 60% and used a negative control of DMSO and positive control of chloramphenicol. From the research that has been done, the extract of the continued life leaves has antibacterial inhibitory power. At a concentration of 20% (10 mm). At a concentration of 30% (11 mm). At a concentration of 40% (12.67 mm). At a concentration of 50% (13.3 mm). At a concentration of 60% (15.3 mm). It can be concluded that the ethanolic extract of the grafted life leaves has the highest antibacterial inhibition at a concentration of 60%, which is 15.3 mm.
PENETAPAN KADAR NITRAT PADA IKAN KALENG SARDEN SECARA SPEKTROFOTOMETRI VISIBLE Simarmata, Yettrie; Nurbaya, Siti; Purwandari, Vivi
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2747

Abstract

Canned fish is a food that is synonymous with preservatives and food coloring. In the manufacturing process, manufacturers often use natural preservatives to lower production costs. This research is descriptive research. The research location is at PT. Mutifa. Aims to determine how much nitrate levels in branded canned sardines are sold at supermarkets in the city of Stabat whether they meet the requirements of SNI or not. From the results of the study, the levels of nitrate with Brand A were 0.00694% and sardines with Brand B were 0.0453% with a maximum wavelength of 435 nm. According to regulations set by the government according to SNI Number 01-35481994 nitrate levels should not be more than 0.2%. From all samples of canned sardines studied, it was found that nitrate levels were low and did not exceed SNI requirements.
ANALISIS TIMBAL (Pb) DAN KADMIUM (Cd) PADA KERANG BULUYANG DIPEROLEH DARI PASAR SEI SIKAMBING MEDAN SECARA KUALITATIF Maimunah, Siti; Sianipar, Artha Yuliana; Zuhairiah, Zuhairiah; Silalahi, Yosy Cinthya Eriwaty
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2748

Abstract

Shellfish (Anadaraantiquata) is one type of shellfish that has the potential to be used as a food source in fulfilling the nutrition of the Indonesian people. Feather clams (Anadaraantiquata) belong to the class Bivalvia which are edible and have economic value. The purpose of this study was to determine the content of lead and cadmium in feather shells. Samples were taken from two fur shell traders at the Sei Sikambing market in Medan using a random sampling method with qualitative testing using disodium sulfide, potassium iodide, potassium chromate, potassium cyanide, and sodium hydroxide reagents, in accordance with work procedures. used in the Medan Regional Health Laboratory. The results showed that of the two samples tested, both samples did not contain lead (Pb) and cadmium (Cd). Keywords: Feather shells, lead (Pb), Cadmium (Cd), Qualitative.
PENETAPAN KADAR PROTEIN DALAM SUSU FORMULA BAYI DAN ASI DI MEDAN SECARA KJELDAHL Sinaga, Eka Margaret; Maimunah, Siti; Sitompul, Erly
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Breast milk (ASI) is the best food for babies. Breast milk has advantages compared to other milk, including guaranteed cleanliness, the composition of breast milk is also very suitable for digestion, growth, and development of babies, one of the compositions contained in breast milk is protein. Currently, many mothers cannot breastfeed their own babies, so they choose infant formula as a substitute for breast milk. The purpose of this study was to determine differences in protein levels in infant formula and breast milk. Determination of protein content was carried out using the Kjeldahl method which is a simple method for determining total nitrogen in protein and other nitrogen-containing compounds. The Kjeldahl method is carried out through 3 processes, namely: the destruction process, the distillation process, and the titration process according to the procedures and tools used in the Chemistry Laboratory of the Sari Mutiara Indonesia University. The results of the determination of protein levels using the Kjeldahl method contained a protein with average levels in infant formula brand A (10.10 -+ 0.96) %, infant formula brand B (10.95 -+ 2.43) %, infant formula brand C (11.0666 -+ 1.6932) %, and breast milk (20.5733 -+ 3.1828) %.
ANALISA CEMARAN LOGAM MERKURI PADA IKAN AIR TAWAR DAN UDANG AIR TAWAR SECARA SPEKTROFOTOMETRI SERAPAN ATOM (SSA) Zuhairiah, Zuhairiah; Sitompul, Erly; Sitorus, Elly; Silalahi, Yosy Cinthya Eriwaty
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Fish containing mercury will have a bad impact on the health of the human body. The maximum limit of mercury levels in fish that has been determined by SNI (2009) on fish is 0.5 mg/kg. This study aims to determine the presence or absence of mercury (Hg) metal contamination in several types of freshwater fish, namely catfish (Clariasgariepinus), catfish (Pangsiushypophthalmus), tilapia (Oreochromis mossambicus), tilapia (Oreochromis niloticus), pomfret (Colossomamacropomum) and giant prawn (Macrobrachiumrosenbergii), by Atomic Absorption Spectrophotometry (AAS). Quantitative analysis of mercury used atomic absorption spectrophotometry (Shimadzu AA-6200). Measured at a wavelength of 253.7 nm. The results of this study were white pomfret containing mercury with levels of 0.2043 -+ 0.0079 mg/kg, catfish containing mercury with levels of 0.4116 -+ 0.1105 mg/kg, catfish containing mercury with levels of 0.4088 -+ 0.1076 mg/kg, tilapia fish contains mercury with levels of 0.4034 -+ 0.1443 mg/kg, tilapia fish contains mercury with levels of 0.4191 -+ 0.0750 mg/kg, and giant prawns contain mercury with levels of 0, 3928 -+ 0.0521 mg/kg. The calculation results show that all types of fresh water fish contain mercury <0.5 in accordance with the requirements set by SNI No.7387 (2009) on fish, namely 0.5 mg/kg.
PENGGUNAAN PATI KENTANG (Solanum tuberosum) LOKAL PREGELATINASI SEBAGAI BAHAN PENGEMBANG PADA TABLET PARASETAMOL GRANUL SECARA KEMPA LANGSUNG Dalimunthe, Agusmal; Thaib, Cut Masyithah; Silalahi, Yosy Cinthya Eriwaty; Tarigan, Mira Eka Diana Br
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Potatoes have a high nutritional content such as carbohydrates, starch, fat, protein, and water. Almost 90% of medicinal raw materials, both active substances and additives are obtained through imports and abroad, even though Indonesia's natural resources can be developed. This study aims to determine the effect of using pregelatinized local potato starch (Solanum tuberosum) as a developer in paracetamol tablets by direct compression. This research was conducted experimentally using five formulas with certain concentrations of F1 (4%), F2 (6%), F3 (8%), and F4 (10%). Then the tablet evaluation test was carried out, namely the weight uniformity test, tablet hardness test, tablet friability test, tablet disintegration time test. The results showed that the paracetamol tablets with local pregelatinized potato starch developer were made to meet the requirements for weight uniformity test, tablet hardness test, tablet friability test, and tablet disintegration time test. It can be concluded that local pregelatinized potato starch (Solanum tuberosum) can be used as a developer in paracetamol tablets.

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