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Silitonga, Maringan
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SOSIALISASI MANFAAT KULIT SALAK YANG MAMPU MENURUNKAN KADAR ASAM LEMAK BEBAS PADA MINYAK GORENG CURAH Eriwaty Silalahi, Yosy Cinthya; Ritonga, Ahmad Hafizullah; Adiansyah, Adiansyah; Silitonga, Maringan
Jurnal Abdimas Mutiara Vol. 2 No. 1 (2021): JURNAL ABDIMAS MUTIARA
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Minyak goreng merupakan salah satu kebutuhan pokok manusia sebagai media pengolahan bahan makanan. Penggunaan minyak goreng yang berulang-ulang dengan pemanasan pada suhu tinggi akan menghasilkan senyawa aldehida, keton, hidrokarbon, alkohol serta bau tengik, yang akan mempengaruhi mutu dan gizi bahan pangan yang digoreng. Alternatif pengolahan minyak goreng bekas adalah melalui proses adsorpsi dengan karbon aktif dari kulit salak. Tujuan pengabdian masyarakat ini untuk memberikan informasi manfaat kulit salak yang mampu menurunkan kadar asam lemak bebas pada minyak goreng curah. Hasil kegiatan pelaksanaan program pengabdian masyarakat dalam bentuk memberikan edukasi dan sosialisasi masyarakat tentang manfaat kulit salak yang mampu menurunkan kadar asam lemak bebas pada minyak goreng curah. Kesimpulan bahwa sosialisasi terlaksana sesuai pelaksanaan dan rencana, mendapat sambutan yang baik dari pemerintah setempat Kelurahan Gedung Johor, Kecamatan Medan Johor Kota Medan, masyarakat sekitar mendapatkan informasi serta pengetahuan.
FORMULASI EKSTRAK TONGKOL JAGUNG (Zea mays L.) SEBAGAI TABIR SURYA DALAM SEDIAAN LOTION UNTUK WAJAH Silitonga, Maringan; Nasution, Pandapotan; Thaib, Cut Masyithah; Haloho, Mei Revolinda
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Corn cobs (Zea mays L.) can be used as sunscreen because it contains phenolic compounds. The purpose of this study was to determine the characteristics of the physical and chemical properties of sunscreen lotion preparations of corncob ethanol extract and the formula and concentration that had the highest effectiveness in the value of Sun Protection Factor (SPF). The lotion was chosen because it is a topical preparation that is often used by the community. Corn cob powder was extracted by the maceration method. The results were formulated with extract concentrations, formulation I (5%), formulation II (10%), and formulation III (15%). The three formulas were tested for organoleptic, pH test, homogeneity, and lotion type. The resulting data were analyzed descriptively. The results showed that all formulas with varying concentrations of extracts had good physicochemical characteristics during storage based on the results of pH, homogeneity, organoleptic, and emulsion-type tests. Corncob ethanol extract sunscreen lotion in Formula 1 (5%) has an SPF value of 2 (UV-A rays) and an SPF value of 7 (UV-B rays). Formula 2 (10%) has an SPF value of 2,3 (UV-A rays) and has an SPF value of 9 (UV-B rays) and Formula 3 (15%) has an SPF value of 3 (UV-A rays) and has a value of SPF 12 (UV-B Rays).
FORMULASI SEDIAAN KRIM LULUR KOPI ARABIKA (Coffea arabica) SEBAGAI ANTI-AGING Purwandari, Vivi; Silitonga, Maringan; Thaib, Cut Masyithah; Sitohang, Isra Kristina
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v5i1.2728

Abstract

Coffee is one of the plantation commodities that has a fairly high economic value among other plantation crops and plays an important role as a source of foreign exchange for the country. Coffee contains important compounds such as antioxidants and caffeine which functions as anti-aging so that it can be used as an anti-aging ingredient in the form of a scrub. The purpose of this study was to determine whether coffee can be formulated in the form of cream as an anti-aging, and in the form of a body scrub cream. The research method using experimental includes the collection of Arabica coffee ingredients, making formulations of Arabica coffee scrub cream preparations, and description of the quality of Arabica coffee cream body scrub preparations. Data analysis in this study used descriptive analysis by presenting the frequency distribution table of each study. The results of the study found that the difference in the concentration of Arabica coffee (Coffea arabica) in body scrub cream preparations had an effect with the best concentration of 15% compared to 5%, 10%, and blank concentrations, and the use of body scrub cream preparations containing Arabica coffee. (Coffea arabica) 15% showed improvement in skin condition for the better, during four weeks of treatment. Thus, Arabica coffee (Coffea arabica) can be formulated in the form of body scrub cream as anti-aging.
UJI AKTIVITAS ANTIOKSIDAN DALAM BEBERAPA MINUMAN YOGHURT DENGAN METODE DPPH (1,1-Diphenyl-2-Picryhydrazil) Simarmata, Yettrie; Sinaga, Eka Margaret; Silitonga, Maringan
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v5i2.2736

Abstract

Antioxidants are chemical compounds that can donate one or more electrons (electron donors) to free radicals to inhibit oxidative reactions. One example that has the potential as an antioxidant is yogurt. Yogurt is a food that contains a number of live bacteria that have a beneficial effect on health because it has antioxidant, antimicrobial, antidiarrheal activity and can boost the immune system. There are several factors that can affect the antioxidant activity of yogurt including temperature, storage conditions, and additional ingredients used such as adding fruit flavors. The purpose of this study was to determine the antioxidant activity of probiotics from yogurt drinks with various brands. Samples were taken from supermarkets in Medan City with 3 different brands coded A, B, and C. The antioxidant activity was determined by the DPPH (1,1-diphenyl-2-picrylhydrazyl) method using a visible spectrophotometer measured at wavelengths. 516 nm. The results showed that there were two samples of yogurt drink coded A and B which were included in the strong category and code C samples were included in the weak category. Yogurt drink with brand code A has the strongest antioxidant activity compared to other brand yogurt drinks (B and C) with IC50 values from samples code A (80.52 ml), B (90.14 ml), and C (194, 81 ml).
PENERAPAN METODE SPEKTROFOTOMETRI SERAPAN ATOM (SSA) DALAM MENGANALISIS LOGAM MERKURI (Hg) PADA KRIM PEMUTIH WAJAH Nurbaya, Siti; Safwan, Ahmad Gazali; Silitonga, Maringan
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2744

Abstract

Whitening cream is a mixture of chemicals and or other ingredients with properties that can fade dark spots on the skin. Whitening cream must be safe and must not contain harmful ingredients such as heavy metal mercury because its toxicity to the organs of the kidneys, nerves, and brain is very strong, so its use is prohibited in cosmetic preparations. The purpose of this study was to determine the levels of metallic mercury (Hg) contained in the preparation of facial whitening creams circulating in Sei Sikambing Market, Medan. The sample used in this study was a facial whitening cream that was not registered with BPOM. The method used to determine mercury levels is qualitatively using color reagents and quantitatively using AAS (Atomic Absorption Spectrophotometry). The results obtained were from 2 samples of facial whitening cream that were used positively for heavy metal mercury (Hg) characterized by the formation of a red-orange precipitate with KI reagent, yellow precipitate by NaOH reagent, white precipitate by HCl reagent. The results of the analysis showed that the highest Hg metal content in the sample with code E was 5.0241 ± 0.4064 g/g. The conclusion of this study is that two samples were positive for mercury, where the use of mercury has been prohibited by BPOM.
IDENTIFIKASI ANTALGIN DALAM JAMU PEGAL LINU SECARA KROMATOGRAFI LAPIS TIPIS Supartiningsih, Supartiningsih; Sinaga, Eka Margaret; Silitonga, Maringan
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2754

Abstract

Traditional medicine is an ingredient or ingredient in the form of plant material, animal material, mineral material, preparation of extracts (galenic), or a mixture of these materials which have been used for generations. Jamu is traditional medicine, in general, herbal medicine cannot cure all kinds of diseases and its natural effect is not as fast as chemical drugs. Lately, medicinal chemicals are often added which are prohibited under the provisions of BPOM (Food and Drug Supervisory Agency). Antalgin is an analgesic-antipyretic and anti-inflammatory drug. Identification of antalgin in herbal aches and pains by thin layer chromatography aims to determine whether the herbal aches and pains circulating around Jalan Captain Muslim, Medan city contain levorphanoll drug chemicals or not. Antalgin identification in herbal pain relief was applied using Thin Layer Chromatography method with 60 F Silica gel stationary phase and chloroform-acetone-toluene (65: 25:10) mobile phase. From the results of identification by thin-layer chromatography (TLC) on herbal pain relief, it was found that the Rf value of the chromatogram spot on the levorphanol 0.16 reference standard was close to the sample Rf value (E) of 0.12. Based on the examination that has been carried out, it can be concluded that the positive herbal pain relief contains levorphanol drug chemicals so that the sample (E) tested does not meet the requirements.
PEMANFAATAN LIMBAH CAIR TAHU MENJADI Nata de Soya MENGGUNAKAN BAKTERI Acetobakter xylinum Purwandari, Vivi; Zuhairiah, Zuhairiah; Marpaung, Jon Kenedy; Silitonga, Maringan
Jurnal Farmanesia Vol 7 No 2 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i2.2774

Abstract

Nata de Soya merupakan salah satu jenis pangan yang diperoleh dari pengolahan limbah cair tahu yang berbahan dasar kedelai. Penelitian ini bertujuan untuk memanfaatkan limbah cair tahu yang sering terabaikan dan menjadi penyebab rusaknya lingkungan perairan dekat perindustrian pembuatan tahu. Nata de Soya dibentuk oleh bakteri Acetobacter xylinum yang merupakan bakteria erob. Masing-masing perlakuan difermentasi selama 8-14 hari, parameter yang diamati yaitu berat nata, kadar air, kadar serat dan selulosa Nata de Soya selama 8-14 hari. Pada penelitian ini didapat data ketebalan Nata de Soya dengan perlakuan 1, 2, dan 3 dengan kosentrasi 5, 10, dan 20% starter bakteri yaitu, 2,4503 gr, 2,8922 gr, dan 2,9226. Pada berat nata didapat 0,21 cm, 0,82 cm, dan 1,53 cm. Kandungan kadar air pada Nata de Soya pada perlakuan 1,2 dan 3 dengan kosentrasi masing-masing 5, 10, dan 20% yaitu 82,71, 83,71%, dan 84,17%%. Kandungan kadar serat Nata de Soya pada perlakuan 1, 2, dan 3 dengan kosentrasa bakteri 5, 10 dan 20% didapat 49,90%, 50,74% dan 54,02%. Pada uji kadar selulosa menggunakan FTIR dengan sampel 0,4 g nilai tertinggi didapat sebanyak 3361,12 menunjukan adanya gugus aldehid dari selulosa acetat. Pemanfaatan limbah cair tahu menjadi Nata de Soya menggunakan bakteri acetobacter xylinum dapat menjadi alternative pengolahan limbah cair tahu.
PEMERIKSAAN CEMARAN Escherichia coli, Shigella sp DAN Salmonella sp PADA SUSU SAPI PERAH YANG DIPEROLEH DARI PETERNAKAN ASAM KUMBANG KECAMATAN MEDAN SELAYANG Zuhairiah, Zuhairiah; Maimunah, Siti; Silitonga, Maringan
Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i1.2785

Abstract

Milk is a drink that is mandatory for consumption by the public, especially for children, therefore, milk must be free from contamination with Escherichia coli, Shigella sp and Salmonella sp bacteria, through the tools used are not clean, the environment is dirty, the hands of workers, and others. This study aims to determine the presence or absence of Escherichia coli, Shigella sp, and Salmonella sp bacteria in Dairy Cow Milk obtained from the Asam Kumbang Farm, Medan Selayang District. The research sample was ten samples of milk from dairy cows in one farm with different cows which were treated with two aseptic and non-aseptic treatments. The research method used is descriptive research with MPN (Most Probable Number) method to count coliform bacteria followed by an examination of LB, BGLB, EMBA media, gram staining, biochemical tests, IMVIC tests, and user testing methods on samples of Shigella sp and Salmonella bacteria sp followed by an examination of NB, SCB, SSA media, gram staining, biochemical tests, and IMVIC. The results showed that one aseptic sample A and 3 non-aseptic samples A, B, C had Escherichia coli bacteria in dairy cows' milk. The quality of milk must comply with the requirements of SNI 3141.1:2011 Fresh Milk Quality and the Maximum Limit of Microbial Contamination in SNI 7388-2009 Fresh Milk.
ANALISIS FAKTOR YANG MEMPENGARUHI PERTUMBUHAN KULTUR SEL CHO (Chinase Hamster Ovarium) PADA PEMBUATAN OBAT TRASTUZUMAB DI PT. BIO FARMA Silitonga, Maringan; Chandra, Devina; Fitri, Raissa; Nanda, Farahlina
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3431

Abstract

This study examines what factors can affect the growth of CHO cell cultures which are often used in biological and medical research and commercially in the production of therapeutic proteins. The purpose of this study was to determine whether CHO cells were able to grow and reproduce with the process flow and manufacturing method of drug preparations in accordance with the requirements of the applicable legislation. The workings of this research are divided into two stages, namely the microbiological stage and the biotechnology stage. The microbiological stage begins with making a working culture, then purification is carried out for culture rejuvenation, harvesting, cell culture breakdown, and purification of target cells. At the biotechnology stage, protein measurements were carried out, Optical Density 600 observations, polyacrylamide gel SDS electrophoresis, and gel electrophoresis staining.
Co-Authors Adiansyah Adiansyah, Adiansyah Chandra, Devina Eka Margareta Sinaga Eriwaty Silalahi, Yosy Cinthya Fitri, Raissa Haloho, Mei Revolinda Marpaung, Jon Kenedy Nanda, Farahlina Nasution, Pandapotan Purwandari, Vivi Safwan, Ahmad Gazali Simarmata, Yettrie Siti Maimunah Siti Nurbaya Sitohang, Isra Kristina Supartiningsih - - Thaib, Cut Masyithah Zuhairiah Nasution, Zuhairiah