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Jurnal Pijar MIPA
Published by Universitas Mataram
ISSN : 19071744     EISSN : 24601500     DOI : -
Core Subject : Science, Education,
Biochemistry, Genetics & Molecular Biology Chemistry Mathematics Physics
Jurnal Pijar MIPA (e-ISSN: 2460-1500 & p-ISSN: 1907-1744) is an open-access scientific periodical journal published by the Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA publishes original articles on current issues and trends in mathematics-science-science education studies. In addition, this journal addresses issues concerning environmental education and environmental science. The journal scopes are: a. Physics and Physics Education b. Chemistry and Chemistry Education c. Biology and Biology Education d. Natural Science and Science Education e. Mathematics and Mathematics Education f. Environmental and Environmental Education
Arjuna Subject : Umum - Umum
Articles 30 Documents
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Search results for , issue "Vol. 21 No. 2 (2026)" : 30 Documents clear
Implementation of Turbidity Sensor Based on IoT for Measuring Seawater Turbidity Levels in Gorontalo Yunus, Muhammad
Jurnal Pijar MIPA Vol. 21 No. 2 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i2.11635

Abstract

Turbidity is the condition of water that is not clear due to suspended particles, such as mud, clay, organic matter, and microorganisms. This research aims to implement an Internet of Things (IoT)- based turbidity sensor to measure seawater turbidity levels in Gorontalo. The IoT-based turbidity sensor system was developed using the SEN-0175 turbidity sensor integrated with an ESP32 microcontroller. The Blynk application serves as a supporting platform for implementing IoT connected to a smartphone. Measurements of seawater turbidity were conducted in three locations in Gorontalo. The result for the first location is an area without residential areas, producing an average turbidity value of 16.5 NTU; the second location is a residential area with several food stalls, producing an average turbidity value of 24.99 NTU; and the third location is a culinary tourism area visited by many tourists, producing an average turbidity value of 50.56 NTU. These results show that the increasing number of human activities in coastal areas has the potential to pollute seawater. Excessive seawater pollution will increase seawater turbidity. Turbidity values exceeding the established seawater quality standards are unsuitable for Marine Tourism and disrupt marine biota; therefore, turbidity concentrations should be no more than 5 NTU. An IoT-based turbidity sensor is suitable for low-cost, real-time monitoring of seawater turbidity in Gorontalo, offering high precision, simple fabrication, and real-time operation.
Computational Evaluation of Vitamin D3 Binding to KRAS and TGF-β1 in Colorectal Cancer–Associated Signalling Pathways Shobahah, Jauharotus; Astuti , Wahyuningsih Sri Puji; Herdiansyah, Mochammad Aqilah; Aly, M. Ainun Najib
Jurnal Pijar MIPA Vol. 21 No. 2 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i2.11643

Abstract

Vitamin D3 has been widely investigated for its anticancer properties, yet the structural basis of its interaction with key oncogenic signaling proteins remains incompletely understood. This study aimed to evaluate the molecular interactions between vitamin D3 and KRAS and TGF-β1 using molecular docking and molecular dynamics simulations. Molecular docking analysis was performed using AutoDock Vina, followed by molecular dynamics simulation using CABS-flex to evaluate structural stability using root mean square deviation (RMSD), root mean square fluctuation (RMSF), and radius of gyration (Rg). Comparative benchmarking was performed against the reference inhibitors Sotorasib (KRAS) and Galunisertib (TGF-β pathway). Docking analysis revealed that vitamin D3 binds to KRAS (PDB ID: 4OBE) with a binding affinity of –7.8 kcal/mol, compared to –8.6 kcal/mol for Sotorasib. The interaction was localized within the nucleotide-binding pocket adjacent to the Switch I and Switch II regions, which are critical for conformational regulation. For TGF-β1 (PDB ID: 3KFD), vitamin D3 demonstrated a binding affinity of –8.2 kcal/mol, slightly exceeding that of Galunisertib (–8.1 kcal/mol), with interaction occurring at the receptor-binding interface. Molecular dynamics simulation showed stable complex formation, with RMSD values of 2.79 Å for the KRAS complex and 1.535 Å for the TGF-β1 complex, indicating acceptable structural stability. Residue fluctuation analysis further supported moderate flexibility without global destabilization. These findings suggest that vitamin D3 may function as a multi-target signaling modulator interacting with both intracellular and extracellular regulators of colorectal cancer pathways, providing a structural basis for further experimental investigation.
In Silico Study of Bioactive Compounds from Koro Benguk (Mucuna pruriens (L.) DC.) as Potential Modulators of CYP7A1 for Hypercholesterolemia Therapy Paradhise, Cleofany Aurhelya; Sari, Trisna Kumala
Jurnal Pijar MIPA Vol. 21 No. 2 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i2.11676

Abstract

Hypercholesterolemia is a major risk factor for cardiovascular diseases and remains a significant global health concern. Cholesterol 7α-hydroxylase (CYP7A1), the rate-limiting enzyme in the classical bile acid synthesis pathway, plays a crucial role in hepatic cholesterol catabolism and represents a promising therapeutic target for cholesterol regulation. Natural product-derived compounds have attracted increasing attention as potential antihypercholesterolemic agents due to their structural diversity and biological activities. However, studies evaluating phytochemicals from Mucuna pruriens as CYP7A1 modulators remain limited, particularly those integrating molecular docking with pharmacokinetic prediction. Therefore, this study aimed to evaluate the potential of bioactive compounds from Mucuna pruriens as modulators of CYP7A1 using an in silico approach. Twenty-eight phytochemical compounds identified through GC-MS profiling were screened using Lipinski’s Rule of Five. Selected compounds were further analyzed by molecular docking against the CYP7A1 protein (PDB ID: 3DAX), followed by ADMET prediction. Docking protocol validation through redocking of the native ligand showed good conformational agreement at the active site (RMSD < 2 Å), confirming the reliability of the docking parameters. Binding affinity and RMSD were used to evaluate ligand–protein interaction stability. Sterculic acid exhibited the strongest binding affinity with a docking score of −6.6.1 kcal/mol and RMSD of 1.51 Å, slightly stronger than the reference ligand 7-ketocholesterol (−7.335 kcal/mol). Interaction analysis revealed hydrogen bonding with key residues, including Asn126 and Lys98, as well as hydrophobic interactions within the active pocket. Other fatty acid derivatives, including octadecanoic acid and heptadecanoic acid, also showed competitive binding energies. ADMET prediction indicated high intestinal absorption (HIA > 90%), no CYP3A4 inhibition, and low predicted toxicity. These results highlight sterculic acid as a promising CYP7A1 modulator and support the potential of Mucuna pruriens phytochemicals for further molecular dynamics studies and experimental validation in the development of hypercholesterolemia therapy.
Functional Food Innovation of Moringa Oleifera L. Seed-Based Plant Yogurt: Fermentation Optimization with Three Lactic Acid Bacteria Putra, Anak Agung Ngurah Dwi Ariesta Wijaya; Sintyadewi, Putu Rima
Jurnal Pijar MIPA Vol. 21 No. 2 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i2.10250

Abstract

Moringa (Moringa oleifera L.) is a nutrient-dense plant with significant potential as a functional food source. Beyond its widely utilized leaves, moringa seeds possess substantial potential due to their high protein and bioactive compound content; however, their current utilization remains limited. This study aimed to evaluate the effect of varying inoculum proportions of three Lactic Acid Bacteria (LAB) species on the characteristics of moringa seed-based plant-based yogurt. The research followed a Completely Randomized Design (CRD), employing various inoculum proportions of Lactobacillus bulgaricus, Streptococcus thermophilus, and Lactobacillus plantarum. Data were statistically analyzed using ANOVA followed by Duncan’s Multiple Range Test (DMRT) at a 95% confidence level. The results indicated that varying inoculum proportions significantly affected the total LAB count, total soluble solids, total acidity, viscosity, pH, proximate composition, and antioxidant activity. The formulation with a 1%:2%:2% ratio (P7) produced moringa seed yogurt with the optimal functional characteristics and consumer acceptance. This study concludes that the synergy among the three LAB species effectively optimizes the quality of moringa seed-based plant-based yogurt. This product has potential as a functional food alternative for individuals with lactose intolerance, while contributing to food security by downstreaming nutrient-rich local commodities.
Utilization of Black Soldier Fly (BSF) Maggots for Organic Waste Decomposition at the Mustika Ikhlas Integrated Waste Management Facility, Tigaraksa, Tangerang Regency Mukhoyyaroh, Qiswatun; Nugraheni, Latif Sofiana; Sari, Indah Anugerah; Amelia, Shabrina Nur Eka
Jurnal Pijar MIPA Vol. 21 No. 2 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i2.11452

Abstract

Waste management challenges in Tangerang have intensified due to the continuous increase in daily waste generation, which is not adequately supported by effective treatment systems, leading to waste accumulation and environmental degradation. This study aims to analyze the utilization of BSF  maggots as a biological agent for organic waste decomposition at the Mustika Ikhlas Integrated Waste Management Facility (TPST), Tigaraksa. The research employed a descriptive qualitative approach conducted from November 2024 to June 2025. Data were collected through in-depth interviews with five key informants who were directly involved in organic waste management and BSF maggot cultivation activities. Data analysis was carried out using thematic analysis, encompassing data reduction, data display, and conclusion drawing. The findings reveal that the BSF maggot-based waste management process consists of several systematic stages, including organic waste sorting and collection, initial fermentation, controlled feeding, biodegradation by maggots, harvesting, utilization of harvested maggots as animal feed, and the reuse of residual media and larval exoskeletons as compost or soil enhancers. Based on field observations, 1 kg of adult BSF maggots can decompose approximately 10 kg of organic waste in 24 hours. Therefore, if the number of BSF maggots raised reaches 10 kg, the volume of organic waste that can be decomposed increases to approximately 100 kg in the same time period. These results indicate that BSF maggot utilization offers an effective, environmentally sustainable, and economically beneficial alternative for organic waste management. Furthermore, the study highlights the potential of BSF-based bioconversion as a scalable, integrated strategy for sustainable waste management in urban and peri-urban areas, particularly in regions with high organic waste generation. This research offers innovation in terms of research location (conducted at TPST Tigaraksa) and study focus (on the maggot cultivation process and its use in organic waste decomposition).
Application of the Jigsaw Cooperative Learning Model Assisted by Solar System Scope Simulation to Improve Learning Outcomes of Junior High School Students Fitria, Alifatul; Martini, Martini
Jurnal Pijar MIPA Vol. 21 No. 2 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i2.11648

Abstract

Science learning on the subject of Earth and the solar system requires learning strategies that can improve students' conceptual understanding so that their learning outcomes improve. This study aims to analyze student learning outcomes using jigsaw cooperative learning assisted by Solar System Scope simulations to improve junior high school students' learning outcomes on the subject of Earth and the Solar System. This study uses a pre-experimental, one-group pre-test-post-test design. Student learning outcomes were measured using pre- and post-tests with a sample of 32 students from class VII-F MTs Negeri 3 Surabaya, and analysed using N-gain and the Shapiro-Wilk normality test. The statistical test used was a non-parametric test, namely the Wilcoxon test. Student learning outcomes increased, yielding an N-gain score of 0.77, interpreted as “High”. The normality test showed that the data were not normally distributed, so the Wilcoxon test was used. The Wilcoxon test results showed a significant difference after jigsaw cooperative learning assisted by solar system scope simulations. Based on these results, jigsaw cooperative learning, supported by solar system scope simulations, is effective in improving student learning outcomes in Earth and solar system material.
Development of an E-Worksheet Based on Problem-Based Learning to Improve Concept Understanding Azzahra, Linda Yudha; Andriani, Aldina Eka
Jurnal Pijar MIPA Vol. 21 No. 2 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i2.11683

Abstract

Science learning in elementary schools still faces challenges in the form of low student conceptual understanding, caused by the lack of digital interactive student worksheets that can facilitate concept visualization and encourage active student involvement in the learning process. This study aimed to design, validate, and examine the effectiveness of E-Worksheet based on Problem-Based Learning to improve sixth-grade students’ understanding of Earth’s rotation and revolution at SDN Kalibanteng Kidul 03, Semarang City. This research employed a Research & Development (R&D) approach using the ADDIE model, comprising analysis, design, development, implementation, and evaluation. The participants were 22 sixth-grade students. Data were collected through interviews, observations, questionnaires, documentation, and pretest–posttest instruments. Data analysis included normality testing, the Wilcoxon Signed Rank Test, and the N-Gain test. The E-Worksheet was developed using Canva, delivered through the Liveworksheet platform, and integrated with Solar System Scope as a virtual laboratory to enhance visualization. E-Worksheet-based Problem-Based Learning consists of a cover page, identity, general information, learning activities, learning activities arranged in stages based on aspects of conceptual understanding and in line with PBL syntax, and developer profiles. Validation results from material and media experts reached 93%, indicating a very feasible category. The Wilcoxon Signed Rank Test showed a significant difference between pretest and posttest scores (Asymp. Sig. = 0.046 < 0.05). The N-Gain score of 0.30 indicates a moderate improvement in students’ conceptual understanding. These findings demonstrate that the E-Worksheet based on Problem-Based Learning is successfully developed, feasible, and moderately effective in improving students’ understanding of Earth’s rotation and revolution. This study contributes a systematic worksheet that integrates PBL syntax with digital simulations and explicit conceptual understanding, serving as a model for developing interactive problem-based digital science materials and as a reference for other science subjects.
Effect of Conceptual Scaffolding in the E-Recitation Program on Students Conceptual Understanding Wendra, Fartin; Nehru, Nehru; Riantoni, Cicyn
Jurnal Pijar MIPA Vol. 21 No. 2 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i2.11686

Abstract

Conceptual understanding is a fundamental aspect of physics learning because each concept is interrelated and becomes the basis for mastering subsequent materials. However, students often experience misconceptions that lead to low conceptual mastery. This study aims to analyze the effect of conceptual scaffolding in the E-Recitation program on students' conceptual understanding of temperature and heat. This study uses a quantitative, experimental approach with a One-Group Pretest-Posttest Design, which involves a single group without a control group. The research subjects were 29 grade XI Science students. The research procedure consisted of three main stages: administering a pretest to measure students' initial abilities, providing treatment by implementing conceptual scaffolding in the E-Recitation program, and administering a posttest to measure changes in conceptual understanding after treatment. The instrument used was a conceptual understanding test comprising 20 multiple-choice questions, validated by experts. The data were analyzed using the Shapiro-Wilk normality test followed by a paired sample t-test to test the hypothesis, as well as to calculate the effect size. The average pretest score of 55.00 increased to 77.24 in the posttest. The analysis results indicate that the data are normally distributed, and the paired-samples t-test is significant (p = 0.000 < 0.05), indicating a significant difference between the pretest and posttest results. In addition, the effect size of 2.07 falls in the very large category. The novelty of this study lies in the direct application of conceptual scaffolding to each answer choice through guiding questions and conceptual feedback videos in the E-Recitation system. Thus, it can be concluded that the application of conceptual scaffolding in the E-Recitation program has a very significant effect on improving students' conceptual understanding of temperature and heat.
Implementation of Contextual Discovery Learning Model to Improve Scientific Literacy Ullum, Iva Tien Nur Hidayatul; Martini, Martini
Jurnal Pijar MIPA Vol. 21 No. 2 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i2.11689

Abstract

Scientific literacy is an essential 21st-century competency that enables students to explain scientific phenomena, design investigations, and interpret evidence-based data. This study aims to analyze the improvement of students' scientific literacy through the application of the Discovery Learning model with a contextual approach to human respiration material. The learning context is developed through a comparative analysis of air pollution data from urban and rural areas, enabling students to examine the relationship between air quality and respiratory system disorders in a real and relevant manner. This study used a quantitative method with a one-group pretest-posttest design. The subjects were 31 eighth-grade students of SMP Negeri 1 Selorejo. The instruments used included a scientific literacy test (pretest and posttest), an observation sheet for learning implementation, and a student response questionnaire. Data analysis was carried out in stages, beginning with a normality test to determine data distribution. Because the data were not normally distributed, hypothesis testing was continued using the non-parametric Wilcoxon test. The magnitude of the increase was calculated through the N-Gain value. The results showed a significant increase in scientific literacy, as indicated by the Wilcoxon test, with an N-Gain of 0.70, which falls within the moderate category. These findings demonstrate that integrating Discovery Learning with a contextual approach grounded in urban and rural air pollution data effectively facilitates students' connections between respiratory system concepts and real-world environmental issues. Thus, this learning model contributes to strengthening scientific literacy competencies in a more meaningful and contextual way.
Integration of the Kungkum Sinden Tradition in Sendang Made for the Development of a Critical Thinking E-book Wulandari, Wiwik; Purnomo, Aris Rudi
Jurnal Pijar MIPA Vol. 21 No. 2 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i2.11694

Abstract

This research focuses on developing an integrated e-book that incorporates the local wisdom of the Kungkum Sinden tradition in Sendang Made into ecosystem learning to enhance junior high school students’ critical thinking skills. The research addresses the limited availability of contextual teaching materials and the need for digital resources that support 21st-century learning, particularly critical thinking and technology integration. A Research and Development (R&D) method was employed using the ADDIE framework, consisting of analysis, design, development, implementation, and evaluation stages. Data were collected through expert validation involving science education lecturers and a science teacher, as well as readability testing. The e-book achieved high validation scores: 3.18 for presentation (valid), 3.32 for content feasibility (very valid), and 3.41 for language appropriateness (very valid), with an overall validity of 83% and a rating of very valid. The product integrates ecosystem concepts with local ecological values and interactive features designed to train interpretation, analysis, inference, evaluation, explanation, and self-regulation skills. In conclusion, the developed e-book is highly feasible and valid for supporting contextual science learning and improving students’ critical thinking skills.

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