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Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Published by Universitas Dharma Andalas
ISSN : -     EISSN : 28099532     DOI : https://doi.org/10.47233/jppie
Core Subject : Health, Science, Education, Agriculture, Art, Engineering,
Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Electrical & Electronics Engineering Energy Engineering Health Professions Industrial & Manufacturing Engineering Library & Information Science Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary
Jurnal Penelitian & Pengkajian Ilmiah Eksakta (JPPIE) merupakan media jurnal elektronik yang diterbitkan oleh Universitas Dharma Andalas sebagai sarana untuk penyebaran dan publikasi hasil penelitian dan pengkajian pemikiran kritis mahasiswa yang orisinil dan up to date. JPPIM memuat artikel bidang Ilmu Eksakta, yang diterbitkan 2 (dua) kali dalam setahun yaitu bulan Januari dan juli. Redaksi menerima artikel hasil penelitian skripsi, tesis dan tugas-tugas perkuliahan mahasiswa.
Arjuna Subject : Umum - Umum
Articles 125 Documents
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Pengaruh Rasio Etanol-Air terhadap Rendemen dan Aktivitas Sitotoksik Ekstrak Daun Azadirachta Indica Sinaga, Samuel Billie Tua; Ramanda, Putri; Mawakhid, Oki Rokhim; Shari, Winda; Wiradimafan, Khafit; ., Avidlyandi; Adfa, Morina
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v5i1.2491

Abstract

Neem leaves (Azadirachta indica) are widely recognized as a rich source of diverse bioactive compounds that exhibit promising pharmacological activities, including anticancer potential. Nevertheless, studies investigating how variations in solvent composition influence extract yield and cytotoxic activity remain limited. Therefore, this research aimed to evaluate the effect of different ethanol–water solvent ratios (50%, 70%, and absolute ethanol) on both the extraction yield of neem leaves and their cytotoxic activity against Artemia salina Leach. The extraction procedure combined sonication and subsequent maceration using the three solvent systems to enhance compound recovery. Cytotoxic assessment was performed through the Brine Shrimp Lethality Test (BSLT) at concentrations of 1000, 500, 100, and 10 ppm, utilizing 48-hour-old larvae with three experimental replicates. Larval mortality was observed after 24 hours of exposure, and LC₅₀ values were determined using probit analysis and linear regression methods. The results demonstrated that extraction with 50% ethanol produced the highest yield (23.5%), followed by 70% ethanol (20.8%) and absolute ethanol (16.10%). In contrast, the strongest cytotoxic activity was observed in the 70% ethanol extract, which exhibited the lowest LC₅₀ value (62.87 ppm), followed by the 50% ethanol extract (64.23 ppm) and the absolute ethanol extract (99.15 ppm). These findings indicate that solvent ratio significantly influences both extraction efficiency and cytotoxic potency; however, extract yield was not directly correlated with cytotoxic activity. Importantly, all extracts demonstrated LC₅₀ values below 100 ppm, suggesting notable toxicity and highlighting their potential as candidates for developing anticancer raw materials.
Penerapan Metode Hazop dalam Identifikasi Bahaya dan Pengendalian Risiko K3 pada Proyek LRT Jakarta Fase 1B Indra, Najwa Putri; Arifin, Ari Syaiful Rahman; Rifwan, Fitra; Andayono, Totoh
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v5i1.2513

Abstract

LRT (Integrated Rail Transit) is a public transportation system developed by PT. Kereta Api Indonesia (KAI) to facilitate mobility for residents of Greater Jakarta (Jabodetabek). The objectives of this study are: 1) identifying high-risk construction projects, 2) applying the HAZOP method to identify hazards and deviations in work processes, 3) assessing risk levels based on likelihood and severity parameters, and 4) providing risk control recommendations based on the HAZOP analysis results. This research is a descriptive analytical study with a qualitative-quantitative approach, conducted on the Jakarta LRT Phase 1B Project, Velodrome–Manggarai Segment, implemented in January 2026. Data collection involved field observations, interviews, questionnaires, and documentation. The results indicate: 1) Identification of High-Risk Work: High-risk construction work in the LRT Phase 1B project includes the use of heavy equipment (jack hammers), concrete casting, girder lifting, electrical installation, and welding processes. 2) The application of the HAZOP method is effective in identifying potential hazards and deviations in various work processes. 3) Risk assessment based on likelihood and severity indicates the greatest risks are in girder lifting and concrete casting. 4) Risk control through technical measures (e.g., low-vibration work methods, strict supervision, use of PPE), administrative measures (SOPs, training), and physical protection (electrical protection, barricades) is essential to reduce occupational risks.
Kajian Model Kinetika Adsorpsi Metilen Biru Menggunakan Karbon Berbasis Ampas Kelapa (Cocos nucifera L.) Etriyanto Arman; Muhamad Alvin Reagen; Sonya Nurizki Vikandari
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v2i1.678

Abstract

Water pollution caused by synthetic dyes, particularly methylene blue, has become a significant environmental concern due to its persistence and potential toxicity to aquatic ecosystems. The utilization of coconut pulp (Cocos nucifera L.) waste as a precursor for adsorbent production represents a promising alternative because of its abundant availability, low cost, and high carbon content, which enable the production of an effective and environmentally friendly adsorbent. This study aimed to investigate the effect of contact time and the adsorption kinetics of methylene blue using carbon derived from coconut pulp waste. Batch adsorption experiments were conducted using 0.2 g of adsorbent in 20 mL of a 50ppm methylene blue solution. The adsorption kinetics were evaluated using the pseudo-first-order and pseudo-second-order kinetic models. FTIR characterization confirmed the presence of characteristic functional groups in the coconut pulp-derived carbon. The adsorption process exhibited increasing adsorption capacity and removal efficiency with increasing contact time until equilibrium was reached, with maximum values of 3.63 mg g⁻¹ and 72.78%, respectively. Kinetic analysis revealed that the adsorption process was better described by the pseudo-second-order model than by the pseudo-first-order model, as indicated by a higher coefficient of determination (R² = 0.9858) and an adsorption rate constant (k₂) of 1.04 × 10⁻¹ g mg⁻¹ min⁻¹. These findings demonstrate that carbon derived from coconut pulp waste has considerable potential as an effective, economical, and sustainable alternative adsorbent for the treatment of dye-containing wastewater.
Analisis Karakteristik Wajik Dengan Modifikasi Perbandingan Konsentrasi Gula Pasir Dan Gula Aren Dewi Arziyah; Ifta Azmi; Anwar Kasim
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 4 No 1 (2025): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v4i1.1875

Abstract

The purpose of this study was to determine the effect of adding various concentrations of palm sugar and granulated sugar on the quality characteristics of diamonds and to determine the most preferred concentration of palm sugar and granulated sugar based on organoleptic tests. This study used a completely randomised design with 5 treatments and 3 replications. Observations made in this study were organoleptic test, water content test, fat content test, and sugar content test. The results showed that the addition of palm sugar and granulated sugar to the diamond had a significant effect (significantly different) on aroma, texture, moisture content, and sugar content.
Implementasi Metode K-Means Clustering untuk Mengklasterikasikan Perangkat Elektronik dengan Teknik Pengolahan Citra Ryan Firmansyah; Agung Ramadhanu
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v5i1.2270

Abstract

Grouping electronic devices such as computers, laptops, and smartphones will be very useful in situations where there are a large number of devices to manage, for example in companies, schools, or service centers. This study uses the k-means clustering method with image processing techniques through the Matlab application. The test data used was taken from the internet, consisting of 30 samples comprising 10 computers, 10 laptops, and 10 smartphones. In accordance with the existing dataset, clustering will be performed on three types of electronic devices, namely computers, laptops, and smartphones. After conducting various tests and model designs, the overall accuracy of the model is 100%. This research can cluster 30 samples consisting of 10 computer images, 10 laptop images, and 10 smartphone images. All samples used were taken from the internet.
Analisis Efektivitas Biaya Pengobatan Pasien Gagal Jantung Dengan Penyerta Hipertensi Rawat Inap RSUD Arifin Achmad Kota Pekanbaru Erda Wati; Nadya Putri Auliya Serawaidi; Siska .
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v5i1.2351

Abstract

Analisis Karakteristik Fisiko-Kimia dan Pengendalian Variabilitas Kualitas Ekoenzim Berbasis Limbah Organik Domestik Maidawati .; Mutiara Yetrina; Rina Sepriana; Susriyati .; Beni Harma
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v5i1.2420

Abstract

Hubungan Penggunaan Obat Golongan Statin terhadap GDS pada Pasien Diabetes Melitus Tipe 2 di Instalasi Rawat Inap Rsup Dr. M. Djamil Padang Tessa Amanda Primadhini; Almahdy A; Dzaskia Arriva
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v5i1.2437

Abstract

Dyslipidemia is one of the risk factors for cardiovascular disease in patients with type 2 diabetes mellitus, so statin therapy is often used to lower lipid levels and prevent cardiovascular complications. Although statins have clear benefits in the management of dyslipidemia, their effect on fasting blood glucose (FBG) levels still needs to be studied. This study aimed to determine the relationship between statin use and FBG levels in patients with type 2 diabetes mellitus. This study used a quantitative descriptive design with a retrospective approach. Data were obtained from the medical records of 82 patients with type 2 diabetes mellitus and dyslipidemia who were treated at the inpatient facility of Dr. M. Djamil Hospital in Padang. All patients in this study received statin therapy. The most commonly used statin was atorvastatin, which was used by 96.3% of patients, while simvastatin was used by 3.7% of patients. The results showed that the average decrease in random blood sugar levels in patients using atorvastatin was 55.65 mg/dL, while in patients using simvastatin it was 84.75 mg/dL. Although there was a numerical difference in the reduction of fasting blood glucose levels between the two statin groups, the difference found was not clinically significant. Thus, this study indicates that the use of statin drugs does not have a significant association with changes in fasting blood glucose levels in patients with type 2 diabetes mellitus.
Gambaran Tingkat Pengetahuan Masyarakat tentang DAGUSIBU Obat di Lingkup Lansia Nagari Aur Begalung Fitri Wahyuni; Yahdian Rasyadi; Wida Ningsih; Cindy Elvionita; Anugrah Putra Pharmaheri
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v5i1.2443

Abstract

In older adults, there is a decline in the ability to adapt to the external environment, accompanied by decreased physiological, cognitive, and psychological functions. These conditions may lead to errors in medication management and use among the elderly. One effort to prevent such problems is the correct implementation of the DAGUSIBU concept (Obtain, Use, Store, and Dispose of medicines). However, the level of knowledge of elderly people regarding DAGUSIBU has not been clearly identified, particularly in Nagari Aur Begalung, Pesisir Selatan Regency. This study aimed to describe the level of knowledge of the elderly community regarding DAGUSIBU medicines in Nagari Aur Begalung. This research employed an observational design with a cross-sectional approach. Data were collected using a structured questionnaire distributed to elderly respondents. The results showed that the majority of elderly respondents had a moderate level of knowledge regarding DAGUSIBU medicines, indicating that their understanding of proper medication management is not yet optimal. Therefore, continuous educational efforts are needed to improve elderly knowledge to ensure appropriate, safe, and rational use of medicines.
Formulasi dan Uji Aktivitas Serum Spray Gel Minyak Adas (Feoniculum Vulgare Mill.) terhadap Bakteri Propionibacterium Acnes Nesa Agistia; Nofriyanti .; Erniza Pratiwi; Mifza Azizah
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v5i1.2449

Abstract

Acne is a prevalent dermatological condition primarily caused by the bacterium Propionibacterium acnes. Antibiotics are used in acne therapy; however, increasing bacterial resistance has been reported in numerous studies. Fennel (Foeniculum vulgare Mill.) essential oil is known to exhibit antibacterial properties, mainly due to its active constituents, anethole and fenchone. This study aimed to develop a pharmaceutically stable serum spray gel formulation containing fennel essential oil and to evaluate its anti-acne activity. Fennel essential oil was formulated into serum spray gel preparations at concentrations of 10%, 15%, and 20%. The formulations were evaluated for organoleptic characteristics, pH, homogeneity, viscosity, flow behavior, adhesiveness, physical stability, spray pattern, and antibacterial activity.The results demonstrated that all serum spray gel formulations exhibited good physical stability, as indicated by acceptable organoleptic properties, homogeneity, pH values, viscosity, flow behavior, adhesiveness, stability, and spray patterns. One-way analysis of variance (ANOVA) revealed a statistically significant difference (p < 0.05) among the formulations in terms of antibacterial activity, as measured by the diameter of the inhibition zones. Post hoc Tukey analysis showed that the 10% fennel essential oil formulation exhibited the highest antibacterial activity, with an inhibition zone diameter of 23.6 mm, which was classified as strong antibacterial activity.

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