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Dian W Damaiyanti
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DENTA JURNAL KEDOKTERAN GIGI Jl. Arief Rahman Hakim No.150, Keputih, Kec. Sukolilo, Kota Surabaya, Jawa Timur 60111 Gedung F6 Fakultas Kedokteran Gigi Telp. 031-5945864
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Kota surabaya,
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Denta: Jurnal Kedokteran Gigi
Published by Universitas Hang Tuah
ISSN : 19075987     EISSN : 26151790     DOI : https://doi.org/10.30649/denta.v16i1
Core Subject : Health,
Dentistry
The Denta (Jurnal Kedokteran Gigi) accepts original manuscripts relating to the field of dentistry, including: research reports, case reports and literature reviews. The spread of dental fields comprise: -Dental material -Endodontics -Forensic dentistry -General dentistry -Oral and maxillofacial surgery -Oral biology -Oral medicine -Oral pathology -Orthodontics -Pediatric dentistry -Periodontics -Prosthodontics -Public health dentistry -Radiographic dentistry -Biomarine Science in Dental field
Arjuna Subject : Kedokteran Gigi - Kedokteran Gigi (Lain-Lain)
Articles 13 Documents
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Search results for , issue "Vol 9 No 1 (2015): Februari" : 13 Documents clear
Pengaruh Pemberian Ekstrak Etanol Daun Mangrove Api-Api Putih (Avicennia Alba) Terhadap Kesembuhan Ulkus Traumatikus Devy Tri Wulandari P; Isidora Karsini S; Dian Mulawarmanti
Denta Journal Kedokteran Gigi Vol 9 No 1 (2015): Februari
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Abstract

Background: Ulcers are common and cause pain, difficulty in speaking, eating and swallowing. Avicennia alba role in the process of wound healing and has been shown to accelerate the healing process of gastric ulcer. It contains flavonoid, saponin, NSLcomponents, minerals and vitamin C, which plays a role in wound healing. Purposes: To prove the effect of ethanol extract of Avicennia alba consentration 10%, 20%, 40% against traumatic ulcer. Materials and Methods: The subjects of this research were 30 wistar rats that were randomized into 5 different groups; K0, K1, P1, P2 and P3. (K0) control, (K1) were given hyaluronic acid, (P1) were given extract of Avicennia alba 10%, (P2) were given extract of Avicennia alba 20%, and (P3) were given extract of Avicennia alba 40%. The subject was wounded using amalgam stopper that has been heated before. Subject was given topical application once daily. The ulcer’s diameter was measured at the second day until the day cured using digital caliper. Data were analyzed using One way ANOVA test. Result: The result showed signification of p<0,05, showed that there were difference diameters betweentwo groups. The average diameter differences of traumatic ulcer among rat are: 0,75 mm (K0), 1,51 mm (K1), 1,01 mm (P1), 2,02 mm (P2), and 1,70 mm (P3). The results showed statistically significant value of p>0.05 which there was no difference in effectivenessAvicennia alba extract in the K1 group. Conclusions: Ethanol extract of Avicennia alba 10%, 20%, and 40% have effect in the healing of traumatic ulcer. The effectiveness of those were the same as giving a 0.2% hyaluronic acid. The concentration 20% of Avicennia alba was effective to the healing of traumatic ulcer
Pengaruh Pemberian Ekstrak Nannochloropsis oculata Terhadap Penurunan Kadar TNF-α pada Tikus yang Diinduksi Bakteri Actinobacillus actinomycetemcomitans Peggie Octavia Halim; Syamsulina Revianti; Yoifah Rizka Wedarti
Denta Journal Kedokteran Gigi Vol 9 No 1 (2015): Februari
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Abstract

Background: Actinobacillus actinomycetemcomitans is a major periodontopathic bacterium with multiple virulence factors, including LPS. LPS is a potent stimulator cytokines proinflammatory such as TNF-α. Nannochloropsis oculata is a green micro algae that hasanti-inflammatory effects. Purpose: The aim of this study was to prove the effect of Nannochloropsis oculata extracts to decreased levels of TNF-α which induced by Actinobacillus actinomycetemcomitans bacteria. Materials and Methods: The experiment was held post test only control group design. 48 male wistar rats divided into 6 groups. K1 group was negative control group without any treatment, K2 group induced by Actinobacillus actinomycetemcomitans bacteria, K3 group treated with minocycline antibiotics 0.1%, and the other groups K4, K5, K6 were treated with Nannochloropsis oculata extract on various concentration that is 2.375%, 2.5%, 2.625%. After treatments on the 37th day, all groups of rats were euthanized and measured the levels of TNF-α in gingival tissue by ELISA. All of thedatas were analyzed by Kruskal Wallis dan Mann-Whitney U test. Result: This study showed the levels of TNF-α K2 group (36.9444) was significantly higher than K1 group(27.8889). K3 group (29.2778) showed no significant decreased compared to K2 group (36.9444). K4 (35.2778), K5 (33.1111) and K6 (29.2778)groups showed no significant decreased levels of TNF-α compared to K2 group (36.9444). Conclusion: Nannochloropsis oculata extracts can not reduce the levels of TNF-α in rats which induced by Actinobacillus actinomycetemcomitans bacteria.
Perbedaan Kitosan Berat Molekul Rendah dan Tinggi Terhadap Jumlah Sel Limfosit pada Proses Penyembuhan Luka Pencabutan Gigi Felinda Gunawan; Sularsih; Soemartono
Denta Journal Kedokteran Gigi Vol 9 No 1 (2015): Februari
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Abstract

Background: Molecular weight is one of the chitosan characteristic that affects the effectiveness application for wound healing of dental extraction. Chitosan could improve wound healing process because of its anti inflammation property and improve proliferation phase. Lymphocyte cell is one of the main cells that act during inflammatory phase. Purpose: the aim of this experiment is to account lymphocyte cell in wound healing of dental extraction using chitosan with different molecular weight. Materials and Methods: 54 Male Rattus Norvegicus were divided into 3 groups. Group I is control group (without chitosan). Group IIwas given low molecular weight chitosan. Group III was given high molecular weight chitosan. Rats were sacrificed by decapitation on day 5 and day 7 post extraction then they were examined histopatologically to see the change in lymphocyte cell number. Result: Data were statistically analyzed with One Way ANOVA and LSD with degree of significant p< 0,05 showed significant difference between high molecular weight chitosan group and low molecular weight chitosan group after 5 and 7 days observation. Conclusion: High molecular weight chitosan was found more effective to decrease lymphocyte cell amounts more than low molecular weight chitosan in wound healing of dental extraction process.

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