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Reni Prastyani
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Department of Opthalmology, Faculty of Medicine, Universitas Airlangga Jalan Mayjen Prof. Dr. Moestopo No. 47, Surabaya, East Java, Indonesia 60131.
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Vision Science and Eye Health Journal
Published by Universitas Airlangga
ISSN : -     EISSN : 2809218X     DOI : https://doi.org/10.20473/vsehj.v1i2.2022.28-34
Core Subject : Health,
Medicine & Pharmacology
Vision Science and Eye Health Journal (VSEHJ) is a peer-reviewed open access scientific journal published by the Department of Ophthalmology, Faculty of Medicine, Universitas Airlangga that welcomes original research, case reports, and scoping or systematic review manuscripts directed to ophthalmologists. VSEHJ focuses mostly on the case report and also welcomes original research and scoping or systematic review related to vision science and eye health that is relevant for the development of the theory and practice of ophthalmology fields. The scope for VSEHJ includes ophthalmology and visual sciences, including corneal or external disease, cataract or anterior segment, glaucoma, neuro-ophthalmology, orbit ocular pathology, pathology or oncology of oculoplastic or orbit, pediatric ophthalmology or strabismus, refractive management and intervention, retina or vitreous, uveitis, community ophthalmology. Each volume of VSEHJ consists of three numbers published every November, March, and July. The first number of volume one was published in November 2021. Articles published in VSEHJ include case reports, original research, and scoping or systematic review articles. Contributors for VSEHJ are researchers, lecturers, students, ophthalmology experts, and other practitioners that focus on ophthalmology worldwide, especially from Southeast Asia Region. Submissions are open year-round.
Arjuna Subject : Kedokteran - Ophthalmology
Articles 71 Documents
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A Case of Chronic Incomplete Vogt-Koyanagi-Harada (VKH) Disease with Systemic Involvement in a 57-Year-Old Woman Prakoeswa, Camilla A.; Zuhria, Ismi
Vision Science and Eye Health Journal Vol. 4 No. 3 (2025): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v4i3.2025.81-85

Abstract

Introduction: Vogt–Koyanagi–Harada (VKH) disease is a systemic disorder that involves tissues containing pigmented cells. It is thought to be caused by an autoimmune T-cell-mediated process against melanocytes in systemic organs, particularly the eyes. VKH disease is a chronic, bilateral, diffuse, granulomatous panuveitis that involves integumentary, neurologic, and auditory aspects, which affects females and darkly pigmented ethnic groups. Here, we presented a rare case of VKH disease in a seronegative spondyloarthropathy patient. Case Presentation: A 57-year-old woman complaining of blurry vision in both eyes for three years. She was previously diagnosed with spondyloarthropathy, osteoarthritis, type 2 diabetes, hypertension, and dyslipidemia. Both eyelids exhibited periocular vitiligo and poliosis and were slightly hyperemic. Both eyes had perilimbal vitiligo and fine brown keratic precipitates. The anterior chambers were deep and quiet; however, the patient had posterior synechiae in both eyes. The fundus examination showed a sunset glow fundus appearance. Conclusions: VKH is a chronic disease that can relapse and recur. While the disease's prognosis is overall favorable, it is determined by the duration and frequency of recurrent inflammation episodes; thus, early detection and prompt treatment are essential for success. Poor visual prognosis is predicted by a larger number of complications, an older age at disease onset, a longer median duration of the disease, delayed treatment initiation, and a higher number of recurrent episodes of inflammation. To preserve vision, patients often require lifelong immunosuppressive therapy and need to be educated about the signs and symptoms to watch for when their condition relapses.
Neurotrophic Keratopathy Post-Herpes Zoster Ophthalmicus Infection Sarasati, Fani; Zuhria, Ismi
Vision Science and Eye Health Journal Vol. 4 No. 3 (2025): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v4i3.2025.91-94

Abstract

Introduction: Neurotrophic keratopathy (NK) is a degenerative disease of the corneal epithelium caused by disruption of corneal trigeminal innervation, resulting in reduced corneal sensitivity, epithelial damage, and impaired corneal healing. It can be caused by various factors, such as viral infections (e.g. herpes simplex keratoconjunctivitis and herpes zoster), chemical or physical trauma, corneal surgery, and intracranial lesions. Management of NK is based on clinical severity to promote corneal healing and prevent progression to stromal melting or perforation. Case Presentation: A 64-year-old male presented with a three-month history of a whitish plaque on the right eye, accompanied by redness, foreign body sensation, and decreased vision. The patient had a history of herpes zoster ophthalmicus (HZO) on the left side of the forehead in June 2022. Ophthalmologic examination revealed a 4 x 5 mm corneal epithelial defect with stromal infiltrates and decreased corneal sensitivity in the left eye, consistent with stage 2 neurotrophic keratopathy. Ancillary tests revealed reduced tear production and instability of the tear film. The patient was treated with topical antibiotics, lubricants, cycloplegics, and systemic doxycycline, with weekly follow-up and no evidence of active bacterial or fungal infection. Conclusion: Neurotrophic keratopathy can occur as a complication of post-HZO infection. Early diagnosis, severity-based treatment, and close monitoring are crucial for achieving epithelial healing and preventing further corneal damage. Prognosis depends on the degree of sensory impairment and the response to treatment.
Use of Artificial Intelligence (AI) as a Diagnostic Modality for Keratoconus: A Comprehensive Meta-Analysis Bulbanat, Ali; Buabbas, Ali J.; Aljassar, Faisal; Alqabandi, Yousif; Alzalzalah, Sayed A. Yousef
Vision Science and Eye Health Journal Vol. 4 No. 3 (2025): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v4i3.2025.72-80

Abstract

Introduction: Keratoconus is a degenerative corneal disorder leading to vision impairment. It is important to detect it early to prevent its progression by corneal cross-linking (CXL). Keratoconus is diagnosed using videokeratography and Scheimpflug tomography, which provide valuable data on the corneal surface. However, distinguishing keratoconus from normal variations remains challenging. Recent advances in artificial intelligence (AI) offer promising improvements in detecting subtle corneal changes, enhancing keratoconus detection and diagnosis. Purpose: To analyze AI as a diagnostic modality for keratoconus by calculating the pooled sensitivity and specificity to evaluate its accuracy. Methods: Databases involved PubMed, Scopus, Google Scholar, Embase, and Science Direct, from 2018 to March 2024. Also, to include unpublished works, the grey literature was searched, using the OpenGrey repository. Studies were included when they met the inclusion criteria. Results: We involved a total of 19 studies in this meta-analysis. The pooled sensitivity for detecting keratoconus was 95% confidence interval (CI) (91% to 98%), with a pooled specificity of 98% CI (96% to 99%). Additionally, the random forest model had a pooled sensitivity of 98.11% (CI, 96.77% to 99.44%), with a pooled specificity of 99% (CI, 98.24% to 99.76%). On the other hand, the convolutional neural network (CNN) model had a pooled sensitivity of 89.73% CI (79.77% to 99.69%), with a pooled specificity of 95.27% CI (91.88% to 98.66%). Conclusion: The results confirmed the reliability of different AI models in diagnosing keratoconus, especially the random forest model. This is important, as the early and accurate detection of keratoconus provides opportunities to reduce risk factors and offer treatments, including CXL, which can potentially slow its progression and improve the patient’s quality of life.
Evaluation of Intraocular Pressure Changes Following Trabeculectomy with Mitomycin-C (MMC): A One-Year Follow-Up Study at Undaan Eye Hospital, Indonesia Kesuma, Raudhatuzzahra; Nuradianti, Lydia; Soraya, Debby; Audina, Rizna
Vision Science and Eye Health Journal Vol. 4 No. 3 (2025): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v4i3.2025.67-71

Abstract

Introduction: Trabeculectomy with mitomycin-C (MMC) is a widely used surgical intervention for the management of glaucoma. This study aimed to evaluate changes in intraocular pressure (IOP) before and after surgery, using statistical analyses of pre-operative and post-operative IOP measurements. Purpose: To determine the effectiveness of MMC in trabeculectomy and its role in enhancing surgical success. Methods: This retrospective observational study analyzed the medical records of 65 eyes from 52 glaucoma patients who underwent trabeculectomy with 2% MMC at Undaan Eye Hospital, Surabaya, Indonesia, between 2022 and 2023. Post-operative IOP was assessed at one, three, six, and twelve months. Statistical analyses were performed to identify patterns of IOP change over time. Results: A Kruskal-Wallis test, followed by Dunn's post hoc analysis (p < 0.001), revealed significant differences in IOP between the pre-operative and post-operative periods (p < 0.05). However, no significant differences were found among post-operative follow-up intervals (p > 0.05). Correlation analysis of IOP categories (< 20 mmHg vs. ≥ 20 mmHg) across observation points showed a negative correlation (r = -0.491, p < 0.001), indicating a tendency for IOP reduction over time. Regression analysis estimated that IOP decreased by approximately 1.141 mmHg per month. Conclusions: Significant reductions in IOP were observed post-operatively, with a sustained downward trend compared to pre-operative values. These findings provide valuable insights into the long-term effectiveness of trabeculectomy with MMC, emphasizing factors that optimize surgical outcomes for glaucoma management.
Subconjunctival Hemorrhage as a Sign of Intraocular Retinoblastoma Progression to Orbital Retinoblastoma Jatikusuma, Anas; Lutfi, Delfitri; Cahyadi, Andi; Heriyawati
Vision Science and Eye Health Journal Vol. 4 No. 3 (2025): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v4i3.2025.95-99

Abstract

Introduction: Retinoblastoma is the most common intraocular malignancy of childhood. While treatable when detected early, a delayed diagnosis can lead to orbital extension, which significantly worsens the prognosis. We report an unusual case in which a subconjunctival hemorrhage signaled the progression of intraocular retinoblastoma to orbital involvement. Case Presentation: A 2-year-4-month-old child presented with a one-month history of left-eye leukocoria. Ocular ultrasound and computed tomography (CT) confirmed features of an intraocular retinoblastoma (Group E), and urgent enucleation was planned. The surgery was delayed by two months; shortly before the operation, the child developed an inferonasal subconjunctival hemorrhage that rapidly expanded. During enucleation, a reddish-brown extrascleral tumor was discovered beneath the hemorrhage, indicating orbital extension. Histopathology revealed Grade 3 retinoblastoma with optic nerve invasion (resection margin free of tumor). Adjuvant chemotherapy was initiated postoperatively. Conclusion: Subconjunctival hemorrhage can be an unusual warning sign of orbital tumor extension in retinoblastoma. This case highlights the importance of raising awareness and reducing diagnostic delays, particularly in resource-constrained settings.
The Impact of Dry Eye Disease on Health-Related Quality of Life Among Elderly Chinese Population in Taiwan: Insights From the Shihpai Eye Study Tsai, Su-Ying; Kuang, Tung-Mei
Vision Science and Eye Health Journal Vol. 5 No. 1 (2025): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v5i1.2025.1-12

Abstract

Introduction: Advanced age is a significant risk factor for dry eye disease. Many individuals tend to perceive dry eye as a minor and inconsequential problem. The significant adverse impact of dry eye on an individual’s health perception cannot be underestimated. This issue demands substantial attention in public health, particularly considering the growing aging population. The present study aimed to investigate the association between dry eye symptoms and signs with health-related quality of life in an Asian elderly population. Purpose: The present study aimed to investigate the association between dry eye symptoms and dry eye signs on health-related quality of life in an Asian elderly population. Methods: This cross-sectional study was conducted within the Shihpai community in Taipei, Taiwan, involving individuals aged 65 years and older who lived independently in the community. A baseline examination was conducted in 1999, consisting of a structured questionnaire that included dry eye symptoms and the 36-item short form health survey (SF-36) questionnaire, followed by a standardized ophthalmic examination that included slit lamp and dry eye tests. Results: Frequent symptoms of dry eye are related to all domains of SF-36 except role limitation due to emotional problems. Schirmer test (≤ 5 mm) was found to have a significant association with greater bodily pain (p = 0.0307) when accounting for other covariates. Additionally, meibomian gland disease exhibited a significant link to lower scores in the domain of role limitation due to emotional problems (p = 0.0406). Conclusions: Our study demonstrated that dry eye, particularly its symptoms, has a significant negative impact on the health-related quality of life in the elderly. It was reported that effective intervention of dry eye could alleviate symptoms of anxiety and depression. Further study will be required to assess whether treatment of dry eye would also improve the health-related quality of life in elderly participants.
Profiles and Outcomes of Traumatic Glaucoma in a Tertiary Eye Hospital Hardjasasmita, Iffa Nadifa Riza; Rifada, Raden Maula; Muslima, Patriotika
Vision Science and Eye Health Journal Vol. 5 No. 1 (2025): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v5i1.2025.13-17

Abstract

Introduction: Traumatic glaucoma is one of the most significant complications from ocular injury. Identifying the cause of elevated intraocular pressure (IOP) in ocular injury, proper management, and lifelong monitoring are essential. Purpose: This study aims to describe the clinical characteristics and outcomes of patients with traumatic glaucoma in a tertiary eye hospital in Indonesia. Methods: This study employs an observational, retrospective cohort design. This study included all patients with traumatic glaucoma who came to the emergency department of Cicendo Eye Hospital, Bandung, West Java, Indonesia, from July 2023 until June 2024. Results: A total of 50 patients with secondary glaucoma due to trauma were included. The majority of patients were male (84%), with a mean age of 34.2 years. Accidents were the most common cause of injury (48%), and 60% of patients presented with severe visual impairment or blindness at initial evaluation. The most common mechanisms of elevated IOP were inflammation (34%) and mixed mechanisms (36%). Treatment was primarily involved in medical management, with 66% of patients returning for follow-up visits. During the six-month follow-up, most patients had poor visual acuity, although the mean IOP significantly decreased. Conclusions: This study emphasizes the importance of early diagnosis and treatment to prevent irreversible visual loss, as well as the need to enhance follow-up care and public health strategies to prevent ocular injuries.
Clinical Improvement in a Patient with Methanol-Induced Optic Neuropathy Rusydiana; Aritonang, Christina; Agustini, Lukisiari
Vision Science and Eye Health Journal Vol. 5 No. 1 (2025): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v5i1.2025.23-27

Abstract

Introduction: Due to optic nerve and retinal damage, methanol-induced optic neuropathy (Me-ION) may lead to permanent vision loss, including blindness, making it a serious condition. Here, we present a case demonstrating clinical recovery in a patient with Me-ION. Case Presentation: A 20-year-old man came to the emergency unit with a chief complaint of sudden visual loss in both eyes since the day before admission. It was accompanied by shortness of breath, headache, nausea, and vomiting. He reported ingesting methanol three days before presentation and had no history of systemic illness. Visual acuity (VA) was counting fingers at one meter in the right eye and counting fingers at three meters in the left eye. The intraocular pressure (IOP) in both eyes was measured at 12.2 mmHg. Optical Coherence Tomography (OCT) of the retinal nerve fiber layer (RNFL) revealed increased thickness in both superior and inferior quadrants bilaterally. Laboratory tests revealed metabolic acidosis. The patient was diagnosed with Me-ION in both eyes, accompanied by metabolic acidosis. Dialysis was started, and he was treated with a high-dose steroid. Subsequently, VA improved to 5/5 in the right eye and 5/12 in the left eye. Color vision improved in the right eye to 30/38 (Ishihara), while the left eye remained at 20/38. Conclusions: Early diagnosis and prompt treatment of Me-ION can result in significant clinical improvement in visual acuity and color vision, emphasizing the significance of early treatment in managing toxic optic neuropathy.
Management Challenges: Resection or Observation due to Astigmatism Refractive Error Associated with a Pediatric Limbal Dermoid Lesion Rahmaniyah, Aisyah; Fatmariyanti, Susy; Deneska, Ria Sandy
Vision Science and Eye Health Journal Vol. 5 No. 1 (2025): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v5i1.2025.18-22

Abstract

Introduction: Limbal dermoid is a congenital benign tumor that contains choristomatous tissue, which may cause astigmatism and lead to amblyopia. This presents management challenges related to limbal dermoids, astigmatism, and amblyopia. Case Presentation: A 10-year-old girl complains of a tumor in the left eye that appeared since two months old, initially small and gradually enlarged. The patient has blurred vision, especially during study. Visual acuity of the right and left eye is 0.33 and 0.15 with best correction visual acuity with left lens power C-3.00 x 10 to 0.67 and right lens power C-7.00 x 0 to 0.33. Anterior segment examination of the left eye revealed a hairy, light brown, soft, solid mass that measured 8 mm x 5 mm x 3 mm located at the limbus and widened towards the cornea and bulbous conjunctiva. Conclusions: Surgery does improve the physical appearance, but unless the young person receives treatment soon, the astigmatic error and visual acuity may not change considerably.
Surgical debridement as a Treatment for Corneal Ulcer due to Gasoline Gyabrina, Asifa; Dwiputra, Pardana; Wara Nandini, Pramadita
Vision Science and Eye Health Journal Vol. 5 No. 1 (2025): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v5i1.2025.28-31

Abstract

Introduction: A Corneal ulcer is an ocular emergency that leads to blindness. It is caused by a defect in the corneal epithelium involving the underlying stroma. Even with prompt treatment, complications such as corneal scarring or perforation, glaucoma, cataract, anterior or posterior synechiae, and blindness may occur. Corneal ulcers can result from trauma or from a disease that allows bacteria or fungi to enter the cornea, leading to infection or inflammation. This study reports a case of a chemical-induced corneal ulcer that did not respond to medical therapy but healed after surgical debridement of the ulcer base. Case Presentation: An 18-year-old man with a history of a right eye chemical injury caused by gasoline. He was presented to the hospital with a complaint of burning in his right eye, blurred vision, watering, glare, and purulent discharge. His right eye slit lamp examination revealed a plaque on the central cornea measuring approximately 6 mm in diameter, with a feathery edge and no hypopyon in the anterior chamber. His visual acuity (VA) in the right eye is 1/60, and in the left eye is 6/8.5. Corneal scraping of the ulcer was sent for fungal culture and microscopy. The result showed Staphylococcus Haemolyticus, a gram-positive bacterium. He was diagnosed with a right eye corneal ulcer bacterial infection with a differential diagnosis of fungal infection. Previously, he had been given a combination of antibiotics and antifungal, and there was no clinical improvement after two weeks; therefore, debridement surgery was performed. VA improved after debridement surgery. The plaque diameter has decreased, and VA has improved. Conclusions: Corneal infection caused by multiple microorganisms is relatively uncommon. The most common risk factor for mixed bacterial and fungal corneal ulcer was ocular trauma. The treatment for a mixed bacterial and fungal corneal ulcer involves topical, systemic, and surgical debridement, with one-month follow-up. The surgical debridement was adequate in handling cases like this and can shorten the healing time of corneal ulcers, as shown by the increase in VA in the right eye from 1/60 to 2/60 at the last visit.

Page 7 of 8 | Total Record : 71

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