cover
Contact Name
Ivandini Tribidasari A.
Contact Email
ivandini.tri@sci.ui.ac.id
Phone
+622129120943
Journal Mail Official
editor_mss@ui.ac.id
Editorial Address
Directorate of Research and Community Engagement UNIVERSITAS INDONESIA UI Campus, Depok 16424 Indonesia
Location
Kota depok,
Jawa barat
INDONESIA
Makara Journal of Science
Published by Universitas Indonesia
ISSN : 23391995     EISSN : 23560851     DOI : https://doi.org/10.7454/mss
Core Subject :
Makara Journal of Science publishes original research or theoretical papers, notes, and minireviews on new knowledge and research or research applications on current issues in basic sciences, namely: Material Sciences (including: physics, biology, and chemistry); Biochemistry, Genetics, and Molecular Biology (including: microbiology, physiology, ecology, taxonomy and evolution); and Biotechnology.
Arjuna Subject : -
Articles 7 Documents
Search results for , issue "Vol. 21, No. 3" : 7 Documents clear
Confirmation of Existing Insulin-like Growth Factor-1 Gene Associated with Growth and Milk-Production Traits and Genetic Diversity in Buffalo Margawati, Endang Tri; Volkandari, Slamet Diah; Indriawati,; Thalib, Chalid
Makara Journal of Science Vol. 21, No. 3
Publisher : UI Scholars Hub

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Abstract

Insulin-like growth factor-1 (IGF-1) gene plays an important role in the endocrine system of animals by regulating nutrient metabolism, growth, and milk production. There have been extensive molecular genetics research studies on cattle but less studies have focused on buffalo (Bubalus bubalis). This study aimed to confirm the association of IGF-1 gene in swamp or river buffalo (B. bubalis spp.) with growth and milk production traits. DNA samples were obtained from 12 buffalos (eight swamp buffalo and four river buffalo). One Bali cattle (Bos javanicus) was included as an outgroup (control). The eight swamp buffalo originated from East Nusa Tenggara (n = 1), Baluran, East Java (n = 4), and Banyuwangi, East Java (n = 3), while the four river buffalo originated from Sei Putih, Medan of North Sumatera. All DNA samples were amplified using an IGF-1 primer for 30 cycles, and amplicons were visualized on 1% agarose gel. Five of the 13 samples were sequenced to determine nucleotide sequence variation between the swamp and river buffalo. The results revealed that the size (225–231 bp) of all the fragments was in in accordance with that of IGF-1. There was not found genetic variation among the buffalo samples. The results indicate that buffalo samples bear growth and milk production traits.
Simultaneous Combination of Electrocoagulation and Chemical Coagulation Methods for Medical Wastewater Treatment Muharam, Salih; Yuningsih, Lela Mukmilah; Rahmah, Citra Ibdau
Makara Journal of Science Vol. 21, No. 3
Publisher : UI Scholars Hub

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Abstract

Chemical coagulation, electrocoagulation, and combined electrocoagulation-chemical coagulation methods were used to reduce organic compound concentrations in medical wastewater. Some parameters in the methods were adjusted to optimize the process, including the applied current, distance between electrodes, number of electrodes, acid levels, coagulant type, and contact time. Chemical Oxygen Demand (COD) was used to indicate the total amount of organic compounds in the system. The results showed that the following conditions can be applied to achieve optimum results: 3 A of applied current, 4 pairs of electrodes, with 1 cm of distance between each electrode pair, a pH of 8, 1 g of polyaluminum chloride as the coagulant, and 3 hours of contact time. The optimum removal efficiency levels of total organic compound achieved via chemical coagulation, electrocoagulation, and the simultaneous combination of electrocoagulation-chemical coagulation methods were 41%, 62.51%, and 92.21%, respectively.
Studies of Power Conversion Efficiency and Optical Properties of Ni3Pb2S2 Thin Films Ho, Soon Min
Makara Journal of Science Vol. 21, No. 3
Publisher : UI Scholars Hub

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Abstract

Ni3Pb2S2 thin films were prepared by using a chemical bath deposition method. In this work, solar cells were fabricated using these materials as absorber layers. Power conversion efficiency testing will be carried out. The results show that these absorbent materials exhibit an open circuit voltage of 0.61 V, a short circuit current density of 9.9 mA/cm2, a fill factor of 0.47 and a power conversion efficiency of 2.7%.
Quantitative Structure-Activity Relationship Analysis of Organophosphate Insecticides Using Electronic and Molecular Parameters Wibowo, Yari Mukti; Mudasir,; Pranowo, Harno Dwi
Makara Journal of Science Vol. 21, No. 3
Publisher : UI Scholars Hub

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Abstract

Quantitative Structure-Activity Relationship (QSAR) analysis of organophosphate derivatives, and their insecticide activities, was performed using electronic and molecular parameters. The series of organophosphate derivatives and their activities were obtained from literature. The semi-empirical AM1 method was used to model the structure of organophosphate derivatives and calculate the parameters of QSAR. Multiple linear regression (MLR) analysis was performed on the electronic and molecular parameters as well as the activities of the organophosphate insecticides to derive the QSAR model. The best QSAR equation model was used to design, in silico, new insecticide molecules of organophosphate derivatives with higher insecticidal activity. A new insecticide molecule, 4-(diethoxy phosphoryloxy) benzene sulfonic acid, -Log LD50 = 7.344, had the highest insecticidal activity. Lastly, we recommend synthesizing and testing the new insecticide molecule further in the laboratory.
Comprehensive Theoretical Studies on 11-MeV Proton Based Tc-99m Production Kambali, Imam
Makara Journal of Science Vol. 21, No. 3
Publisher : UI Scholars Hub

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Abstract

The shortage of nuclear-reactor-based Tc-99m supply has led to increased research on cyclotron-based Tc-99m production. In this paper, Tc-99m radionuclides produced by a 11-MeV proton cyclotron is theoretically discussed in terms of the optimum thickness of natMo, natMoO3, and enriched 100Mo targets; expected impurities; and radioactivity yields of several (p,2n), (p,n), and (p,γ) based nuclear reactions. The SRIM 2013 codes and TALYS 2014 codes are employed to calculate the range of 11-MeV proton beams in the Mo-based targets and the excitation functions of the selected nuclear reactions, respectively. The calculated results indicate that 94m,95m,96mTc radionuclides would give rise to radionuclide impurities at the end of irradiation for natMo targets, whereas no significant impurities were theoretically detected for the enriched 100Mo target. At the end of bombardment, nearly 42.18 GBq/µA.hr of Tc-99m radionuclide is predicted to result in the 11-MeV proton-irradiated 100Mo target.
Biodegradation of Used Synthetic Lubricating Oil by Brevundimonas diminuta AKL 1.6 Basuki, Witono
Makara Journal of Science Vol. 21, No. 3
Publisher : UI Scholars Hub

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Abstract

Illegal disposal of used lubricating oil is a serious hazard to the environment and public health. This study is aimed at examining the biodegradation process of used synthetic lubricant using local microorganism. Oil-degrading microorganism were obtained from sea water contaminated with used lubricating oil. Those that showed some growth activity in Bushnell-Haas media containing used synthetic lubricating oil as a sole carbon source were selected. Its single colony was then generated by performing the dilution and scratch technique in the isolation and purification process. By using 16s rDNA, a potential strain namely AKL 1.6, was identified as Brevundimonas diminuta. Gas chromatography analysis was performed before and after the biodegradation process of the used oil. As a result, B. diminuta AKL 1.6 was found to utilize used synthetic lubricating oil as the sole source of carbon and to degrade most of the hydrocarbon within the oil for 14 days. Thus, this particular microorganism has the potential to be the single microbe for bioremediation of sea water contaminated by lubricating oil.
Deposition and Characterisation of Pd-xSb2S3 Thin Films for Sustainable Solar Energy Applications Nwofe, Patrick; Idenyi, Ndubisi Edennaya
Makara Journal of Science Vol. 21, No. 3
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Abstract

This study reports on the effects of different concentrations of palladium impurities on the optical and compositional properties of palladium-doped antimony sulfide (Pd-xSb2S3) thin films grown by the chemical bath deposition method. The films were grown at room temperature (25 °C) with other condition, such as pH at 3.2 and the complexing agent (polyvinyl alcohol), was kept constant. The concentration of the dopants was varied between 0.3 and 0.5 M. The films were annealed at an annealing temperature of 100 °C with the annealing time of 90 min. The films were characterized using the Rutherford backscattering spectrometry (RBS) techniques and optical spectroscopy (transmittance versus wavelength and absorbance versus wavelength) to investigate the composition and optical constants (optical absorption coefficient, energy bandgap, and extinction coefficient), respectively. The results show that the transmittances of the doped layers were higher than that of the as-deposited layers. The energy bandgap of the layers was direct and typically ≤ 2.80 eV.

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