cover
Contact Name
Murdani Abdullah
Contact Email
ina.jghe@gmail.com
Phone
+6285891498517
Journal Mail Official
ina.jghe@gmail.com
Editorial Address
Divisi Gastroenterologi, Departemen Ilmu Penyakit Dalam, FKUI/RSUPN Dr. Cipto Mangunkusumo, Jl. Diponegoro No. 71 Jakarta 10430 Indonesia
Location
Kota adm. jakarta pusat,
Dki jakarta
INDONESIA
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
ISSN : 14114801     EISSN : 23028181     DOI : -
Core Subject : Health,
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy is an academic journal which has been published since 2000 and owned by 3 Societies: The Indonesian Society of Gastroenterology; Indonesian Association for the Study of the Liver; The Indonesian Society for Digestive Endoscopy. The aim of our journal is to advance knowledge in Gastroenterology, Hepatology, and Digestive Endoscopy fields. We welcome authors for original articles, review articles, and case reports in the fields of Gastroenterology, Hepatology, and Digestive Endoscopy.
Articles 771 Documents
Primary Lymphoma of The Gastrointestinal Tract Agus Sudiro Waspodo; Kukuh B. Rachmat; Wirasmi Marwoto; Ali Sulaiman; A H Reksodiputro
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 2, NUMBER 1, April 2001
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/21200136-40

Abstract

Chronic hepatitis due to hepatitis B virus (HBV) or hepatitis C virus (HCV) is still a major problem in terms of progressive liver damage, prevention and therapy in most parts of the world. Unfortunately, to date, there is still no specific and effective therapy for HBV. No therapy can be given to carrier, non- replicative and asymptomatic patients of chronic HBV infection. Lamivudine or alpha-interferon can be used for treatment of compensated, chronic hepatitis B infection with significant increase of aminotransferase. Approximately 40 % of patients can have seroconversion with this form of therapy. Chronic hepatitis D virus infection can be treat with alpha-interferon and in the final stage, may undergo liver transplantation. For chronic hepatitis C virus infection, alpha-interferon with ribavirin have been shown to have a better efficacy than alpha-interferon alone where the efficacy can reach 39 – 49 %.    Keywords: hepatitis, interferon, lamivudin,ribavirin
Prevalence of Hepatitis B and C Infection Among Street Children Community in Malang City Syifa Mustika; Charisma Dian Simatupang
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 21, No 1 (2020): VOLUME 21, NUMBER 1, April 2020
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (83.149 KB) | DOI: 10.24871/211202012-16

Abstract

Background: World Health Organization (WHO) announced that during 2017, 325 million people worldwide were infected with the hepatitis B virus (HBV) or hepatitis C virus (HCV). Street children community is a part of society that is susceptible to HBV and HCV transmission, yet no data available about the prevalence. The purpose of this study was to determine the prevalence of hepatitis B and hepatitis C infections in street children community of Malang during 2017.Method: This cross-sectional study was conducted in September 2017 with subjects of street children who were members of the East Java Humanitarian Network (EJHN) group. They were interviewed, got vital signs examined, and performed HBsAg and anti HCV tests using the ECLIA method.Results: There were 90 subjects, with more male than female (60%). The most frequent age range was between 21 to 30 years (35.6%). Most of them do not have permanent jobs (37.8%). The level of education varied, with 30% were at the level of primary education and 56.7% were married. There were 4.4% hepatitis B positive and 1.1% of hepatitis C positive among the subjects. Subjects with positive results had history of free sex, tattoos, and intravenous drugs abuse as the risk factors of HBV and HCV transmission.Conclusion: The prevalence of Hepatitis B and Hepatitis C in the population of street children in Malang city, East Java, were 1.1% and 4.4%, respectively. The most common risk factors were free sex and tattoos.
Nosocomial Clostridium difficile Diarrhea in Patient with Malignancy Andree Kurniawan; Ari Fahrial Syam; Nata Pratama; Resti Mulya Sari; Khie Chen
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 12, NUMBER 2, August 2011
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (948.419 KB) | DOI: 10.24871/1222011127-132

Abstract

Clostridium difficile (C. difficile) is the main pathogen causing antibiotics associated diarrhea and colitis. This bacterium increases with hospitalization with incidence of 20-60 cases per 100,000 patients/day. C. difficile is gram positive bacilli which produce toxins in 2,700 cases in every 100,000 exposures to particular antibiotics, such as clindamycin, cephalosporin, and ampicillin. These antibiotics disrupt the intestinal normal flora and predispose to colonization of C. difficile. This case described a 53-year old male patient with squamous cell carcinoma in his left ear who came to Department of Internal Medicine, Cipto Mangunkusumo Hospital, with the complain of diarrhea since two weeks after one month hospitalization in Department of Ear, Nose, and Throat. The characteristics of the diarrhea were 10 times per day ± 100 mL, watery consistency, green yellowish in color, and no blood in the feces. Additionally, the patient also complained of pain in all parts of his stomach, especially in the epigastric area. Earlier, patient was given ceftazidime for 30 days of hospitalization. The serology examination of C. difficile in the feces showed positive result (titer = 0.790 and control = 0.190). During the colonoscopy examination, pancolitis was found and the pathologic anatomy result was found appropriate for infective colitis. Thereafter, antibiotic administration was ceased and metronidazole was administered intravenously three times a day. The diarrhea stopped after seven days and the patient was discharged. Keywords: Clostridium difficile, nosocomial diarrhea, malignancy
Gastroesophageal Reflux Disease in Push Up and Sit Up Exercise B J Waleleng; D Takaendengan; N Tendean W
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 8, ISSUE 1, April 2007
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/81200710-15

Abstract

Background: Several factors involve in GERD are hypotension of Lower Esophageal Sphincter (LES), Transient Lower Esophageal Sphincter (TLES) relaxation, delayed gastric emptying and esophageal hiatal hernia. Bent over and supine position like push up and sit up exercise in this study, are known as trigger factors for GERD which can cause hypotension of the LES, TLES relaxation and transdiaphragmatic pressure resulted in increased diaphragmatic nerves activation. Aim: The purpose of this study was to investigate the occurrence of GERD in push up and sit up exercise. Materials and Methods: This is an experimental study; subjects were healthy male aged 18-21 years. Patients data were collected after fulfilling the selection criteria as described in the study protocol. χ2 analysis or Fischer’s exact test analysis was applied to determine the statistical significance of difference between push up and sit up. There were 30 subjects in the study, 15 subjects in push up group and 15 subjects in sit up group. Result: Three subjects (10%) were dropped out and 27 subjects (90%) were endoscopied. In the sit up group, 13 subjects (87%) were endoscopied, 9 subjects (70%) had normal endoscopy and 4 subjects (30%) had mucosal breaks. In push up group, 14 subjects (93%) were endoscopied, 6 subjects (43%) had normal endoscopy and 8 subjects (57%) had mucosal breaks. There was no significant difference between push up and sit up group with χ2 analysis or Fischer’s exact test (p = 0.322). Conclusion: There was more likely GERD in push up group than in sit up group, but the difference was not significant.   Keywords: push up exercise; sit up exercise, gastroesophageal reflux disease (GERD)
Palliative Stenting With or Without Radiotherapy for Inoperable Esophageal Carcinoma Yaldiera Utami; Achmad Fauzi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 16, No 2 (2015): VOLUME 16, NUMBER 2, August 2015
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (171.949 KB) | DOI: 10.24871/1622015130-136

Abstract

Aim: to evaluate the comparison of palliative treatment using esophageal stenting alone or in combination with radiotherapy.Method: Patient/problem, intervention, comparison, and outcome (PICO) system were used. We conduct a searching in PubMed site. The next process was selection by reading all articles (10 articles). There were 9 articles excluded from analysis. We finally choose one randomized trial study written by Javed A, Pal S, Dash NR, Ahuja V, Mohanti BK, Vishnubhatla S, et al goes to the critical appraisal step.Results: The result of this study showed that dysphagia scores improved significantly in both groups, in patients with inoperable esophageal cancer treated with esophageal stenting alone (group I) and a combination of esophageal stenting and radiotherapy (group II) following stent insertion. However, dysphagia relief was more sustained in Group II than in Group I (7 vs. 3 months, p = 0.002).Conclusion: In this evidence-based case report (EBCR), we reported a man who suffered from dysphagia caused by inoperable esophageal carcinoma. Based on the critical appraisal of the randomized trial collected previously from PubMed with specific criterias, we conclude that a combination of esophageal stent and radiotherapy effectively prolongs duration of dysphagia relief and improves the overall survival, without increasing the incidence of complications.
Association Between Degree of Gastritis and Malondialdehyde Level of Gastritis Patients at Adam Malik General Hospital Medan Darmadi Darmadi; Gontar Alamsyah Siregar; Leonardo Basa Dairi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 18, No 2 (2017): VOLUME 18, NUMBER 2, AUGUST 2017
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (400.333 KB) | DOI: 10.24871/182201780-85

Abstract

Background: The main pathogenesis of gastritis is inflammation which process can not be separated from the role of free radicals. Malondialdehyde (MDA) is a free radical biomarker and which increases in gastritis patients. However, studies on MDA were generally performed on experimental animals or examined MDA in gastric mucosa. The aim of this study is to determine the association of histopathological degrees of gastritis (the degree of lymphocyte infiltration, neutrophil activity, atrophy, and intestinal metaplasia) with plasma MDA level.Method: Cross-sectional study of 40 consecutive gastritis patients who came to endoscopic unit of Adam Malik General Hospital Medan, from January to May 2017. Assessment for the severity of chronic inflammation, neutrophil activity, atrophy, and intestinal metaplasia refers to Updated Sydney System. Plasma MDA levels were examined using an HPLC MDA kit. Univariate and bivariate (Chi-square and fisher exact test) analysis were performed with SPSS version 22.Results: A total of 26 patients (65%) were men with an average age of 49.25 years. Lymphocyte infiltration was observed in 100% of specimens, neutrophil infiltration in 37.5%, atrophy in 22.5%, and intestinal metaplasia in 22.5%. There was a significant association between degree of lymphocyte infiltration with MDA level (p = 0.014; PR = 8.667; 95% CI: 1.52-89.52). There was a significant association between degree of neutrophil activity with high MDA level (p = 0.002; PR = 11.33; 95% CI: 2.64-48.74). There was a significant association between degree of atrophy with high level of MDA (p 0.001; PR = 14; 95% CI: 3.4–57.648). There was a significant association between degree of intestinal metaplasia with high MDA level (p = 0.001; PR = 12.5; 95% CI: 3.76-24).Conclusion: There were significant associations between degree of lymphocyte infiltration, neutrophil activity, atrophy, and intestinal metaplasia with high level of MDA.
Alterations in Blood Ammonium Level and Psychometric Test in Patients with Liver Cirrhosis after a Tempe Diet Neneng Ratnasari; Siti Nurdjanah
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 3, NUMBER 2, August 2002
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/32200233-37

Abstract

Background: Hepatic encephalopathy is found in 50-70% cases of liver cirrhosis. Management of hepatic encephalopathy is based on the hypothesis of ammonia and false neurotransmitters. A vegetable diet is the diet of choice, since vegetable proteins have a high biological value, contains non- ammonigenic essential amino acids, and contains fiber. The results of soy fermentation by Rhizopus sp can increase the nutritional value to make it easier for body digestion. Study aim: To determine improvements in hepatic encephalopathy by measuring the ammonium level and determining the psychometric test in patients with liver cirrhosis receiving a tempe diet compared to those receiving a liver diet (conventional diet). Method: This is a random open clinical trial with a proportional stratification according to the Child Pugh criteria. Study subjects are patients with liver cirrhosis who are hospitalized at the Internal Medicine Ward and ambulatory patients at the out-patient Gastro-hepatology Polyclinic of Dr. Sarjito Public General Hospital, from January 1999 to May 2000. The trial was conducted for 20 days, where the first (trial) group is given a tempe diet, while the second (control) group is given liver diet II/III (conventional). Measured outcomes include peripheral blood ammonium level, and psychometric test using the Numeric Connection Test (NCT). Results: In the first group, we found a significant reduction of ammonium level in Child-Pugh A patients and a non-significant reduction in Child-Pugh B/C patients, a non-significant psychometric test improvement in Child-Pugh A patients, and significant psychometric test improvement in Child-Pugh B/C patients. In group II: there is no significant difference in the changes in ammonium level or psychometric test in patients from both Child-Pugh categories. Conclusion: A 20-day tempe diet can reduce ammonium levels and improve results on the psychometric test.   Keywords: lever cirrhosis, hepatic encephalopathy, tempe diet, numeric connection test, child-pugh criteria
Constipation in Elderly Population and Its Appropriate Management Alvin Hartanto Kurniawan; Ulfa Kholili; Novira Widajanti
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 21, No 3 (2020): VOLUME 21, NUMBER 3, December 2020
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (495.59 KB) | DOI: 10.24871/2132020212-219

Abstract

Constipation is a gastrointestinal disorder commonly found in the community, especially in the elderly with various comorbidities. This problem culminates with the increasing incidence along with aging, increasing therapeutic cost, and decreasing the quality of life in this population. Some of the underlying causes are the difference in the terminology of constipation, shallow understanding of its pathophysiology, and poor management. The pathophysiology, including slow transit constipation, dyssynergic defecation, and normal transit constipation, is the most critical foundation in managing constipation accordingly. Diagnostic approaches should be made by history taking, including complaints based on Rome III, lifestyle, contributing factors, past medical history, and medications. Physical examination is considered incomplete without rectal examination. Thorough history taking and comprehensive physical examination have more diagnostic value than additional physiological workup. Management of constipation consists of non-pharmacological and pharmacological approaches, such as conventional laxative or more recent agents with better efficacy. Therapeutical management should correspond to the underlying pathophysiology. Therefore it is important to be able to recognize constipation and make the right management approach in the elderly.
Etiology Profile of Lower Gastrointestinal Bleeding Masrul Lubis; Lukman Hakim Zain
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 13, NUMBER 2, August 2012
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (586.764 KB) | DOI: 10.24871/132201294-96

Abstract

Background: Lower gastrointestinal bleeding (LGIB) is still a significant health problem since the unknown etiology had not existed until now. Similar condition occurs at Adam Malik Hospital. No data about the etiology of LGIB has been defined. Therefore, this study was aimed to recognize the etiology profile of LGIB at Adam Malik Hospital, Medan. Method: A retrospective descriptive study was conducted on medical records of patients who had undergone lower gastrointestinal tract endoscopy (colonoscopy) at Adam Malik Hospital, Medan between January 2009 and December 2010 based on their complaint of hematochezia. Data was analyzed using SPSS version 19. The data was categorized based on subjects’ age, sex and etiology of their hematochezia. Results: There were 116 patients consisted of 61 (52.6%) males and 55 (47.4%) females with mean age of 50.52 (17-84) years. The colonoscopy revealed 52 (44.7%) cases of hemorrhoidal varices, 17 (14.7%) cases of rectal carcinoma, 17 (14.7%) normal endoscopic results, 8 (6.9%) cases of sigmoid carcinoma, 8 (6.9%) of proctitis, 6 (5.1%) cases of colitis, 4 (3.5%) cases of colon carcinoma, and 4 (3.5%) cases of rectosigmoid carcinoma. Conclusion: This study found that hemorrhoidal varices is the most common etiology of LGIB. Keywords: LGIB, colonoscopy, hemorrhoids
Seroprevalence Study of HbsAg positive in Entrant Candidates of Specialist Doctoral Program at Dr. Kariadi Hospital Semarang Hery Djagat Purnomo; Suyatmi Awizar
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 9, ISSUE 2, August 2008
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/92200842-44

Abstract

Background: Hepatitis B Virus (HBV) infection is one of main diseases that infects human kind and constitutes a serious health problem in community. As a consequence of their job, health personnel have gained higher risk to HBV infection. Medical personnel (doctors) are determined as one of the high-risk group of the HBV infection through blood transmission.The objective of this study was to determine the prevalence of HBsAg positive in doctors who were entrant candidates of medical specialist program at Dr. Kariadi hospital. Method: The study was conducted retrospectively by reviewing medical record of 1,145 doctors who were entrant candidates of medical specialist program at Dr. Kariadi hospital since April 2000 to October 2004. The HBsAg assay as a marker of HBV infection was analyzed by EIA (Enzyme Immuno Assay) Method. Results: Among the 1,145 doctors examined , the range of age was 29.34 ± 3.04 years, and more than 3-year work period as doctor was 64% (733/1,145), and less than 3-year work period as doctor was 36% (412/1,145). The prevalence of HBsAg positive in population was 3.9% (45/1,145). The seropositive of HBsAg in the group of doctors with more than 3-year work period was significantly higher than the group with less than 3-year work period (5.1% (38/73) vs. 1.6% (7/412) with p 0.05. Conclusion: The prevalence of HBsAg positive in doctors who were entrant candidates of specialist doctoral program at Dr. Kariadi hospital was 3.9%. The prevalence of infection was higher in the group of doctors with more than 3-year work period.   Keywords: prevalence, HBsAg, doctor

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