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Hafiz Muchti Kurniawan
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Program Studi Farmasi UNAJA Jl. Sersan Muslim RT.24 Kelurahan Thehok Kecamatan jambi Selatan 081334089241 (Septa Pratama) Kota Jambi, Jambi , Indonesia lppm@unaja.ac.id 081334089241 (Septa Pratama)
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PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Published by Universitas Adiwangsa Jambi
ISSN : -     EISSN : 28306090     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Pharmanaja : Pharmaceutical Journal of Unaja merupakan jurnal elektronik yang dikelola Program Studi Farmasi Universitas Adiwangsa Jambi. jurnal ini merupakan media publikasi hasil penelitian dan review artikel pada semua aspek ilmu Farmasi yang bersifat inovatif, kreatif, Original, dan didasarkan pada scientific dalam bidang kajian farmasi klinis komunitas, farmasi bahan alam, kimia farmasi, teknologi farmasi, farmakologi, toksikologi, managemen farmasi, farmasi umum, mikrobiologi farmasi.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 44 Documents
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Uji efek Hipnotik Sedatif ekstrak etanol Daun Ubi Jalar (Ipomoea batatas) terhadap Mencit Jantan Galur Swiss William Leslie
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 3 No. 1 (2024): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Abstract

This study aimed to evaluate the hypnotic and sedative effects of ethanol extract from sweet potato leaves (Ipomoea batatas) in male Swiss mice. The experiment was conducted at the Pharmacology Laboratory, Universitas Adiwangsa Jambi. Mice were divided into five groups: negative control (0.5% NaCMC), positive control (diazepam 1 mg/kg BW), and three treatment groups receiving ethanol extract of Ipomoea batatas leaves at doses of 200, 400, and 600 mg/kg BW. Hypnotic effect was evaluated using sodium pentobarbital-induced sleep (50 mg/kg BW, i.p), with onset of sleep and sleep duration as observed parameters. The results demonstrated that the extract at 400 and 600 mg/kg BW significantly reduced sleep onset time and prolonged sleep duration compared to the negative control (p<0.05). The highest dose showed effects comparable to diazepam. These findings indicate the potential of Ipomoea batatas ethanol leaf extract as a natural sedative agent, supporting its traditional use and opening opportunities for phytopharmaceutical development.
Pengaruh Perak Merah (Pemberian Ekstrak Melia Azedarach atau daun Mindi) Terhadap Tekanan Darah Tikus Putih Galur Wistar (Ratus Norvegicus) Yang diinduksi DOCA-Salt (Deoxycorticosterone acetate) Bartimeus Nicomama Hutabarat
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 4 No. 1 (2025): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Abstract

Hypertension is a major degenerative disease and one of the leading causes of global morbidity and mortality. This study aimed to evaluate the effect of Melia azedarach (perak merah) leaf extract on blood pressure in DOCA-salt-induced hypertensive Wistar rats (Rattus norvegicus). The study was conducted at the Laboratory of Universitas Adiwangsa Jambi using a post-test only control group design. Rats were divided into five groups: normal, hypertensive (DOCA-salt), and three treatment groups receiving graded doses of Melia azedarach leaf extract. The results showed that the extract significantly reduced both systolic and diastolic blood pressure compared to the hypertensive control group (p < 0.05). The most pronounced antihypertensive effect was observed at the intermediate dose, indicating an optimal pharmacological response at this level. These findings suggest the potential of Melia azedarach as a natural antihypertensive agent, supporting its role in the development of complementary therapies for hypertension.
Uji efektivitas Antibakteri Ekstrak Kulit Pisang Kepok (Musa parasidiaca L.) Terhadap Bakteri Staphylococcus dan Salmonella typhi Benny Hartono
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 4 No. 1 (2025): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Abstract

This study aims to evaluate the antibacterial effectiveness of kepok banana (Musa paradisiaca L.) peel extract against Staphylococcus aureus and Salmonella typhi. The research was conducted at the laboratory of Universitas Adiwangsa Jambi. The banana peel extract was obtained through maceration using 96% ethanol as a solvent. Antibacterial activity was tested using the disc diffusion method against both bacterial strains. The results showed that the extract exhibited significant antibacterial activity, as indicated by the inhibition zones formed at various extract concentrations. The highest extract concentration produced the largest inhibition zones, with 15.2 mm against Staphylococcus aureus and 13.8 mm against Salmonella typhi. These findings suggest that kepok banana peel extract has potential as a natural antibacterial agent effective against both gram-positive and gram-negative bacteria. This opens the opportunity for utilizing banana peel waste as a plant-based antibacterial alternative.
Faktor-Faktor eksogen yang Berhubungan dengan Kejadian Dermatitis Kontak Akibat Kerja(DKAK) pada Pekerja Batik di Jambi Desi Primayani
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 4 No. 1 (2025): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Abstract

Occupational Contact Dermatitis (OCD) is among the most prevalent occupational skin diseases, particularly affecting informal sector workers such as batik artisans who are chronically exposed to chemical substances. This study aimed to identify exogenous factors associated with the incidence of OCD among batik workers in Jambi. A quantitative approach with a cross-sectional design was applied, involving a number of respondents from several batik production centers in Jambi. Data were collected using structured questionnaires and analyzed using chi-square tests and logistic regression to examine the associations between exogenous variables—including duration of exposure, type of chemicals, use of personal protective equipment (PPE), and frequency of contact—and the occurrence of OCD. The results revealed significant associations between inconsistent use of PPE, chemical exposure duration exceeding five years, and high contact frequency with OCD incidence (p < 0.05). These findings underscore the need for preventive interventions through enhanced PPE utilization and education on chemical hazards among batik workers. This study contributes to the development of more adaptive occupational health strategies in home-based industries.

Page 5 of 5 | Total Record : 44

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