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Program Studi Farmasi UNAJA Jl. Sersan Muslim RT.24 Kelurahan Thehok Kecamatan jambi Selatan 081334089241 (Septa Pratama) Kota Jambi, Jambi , Indonesia lppm@unaja.ac.id 081334089241 (Septa Pratama)
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PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Published by Universitas Adiwangsa Jambi
ISSN : -     EISSN : 28306090     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Pharmanaja : Pharmaceutical Journal of Unaja merupakan jurnal elektronik yang dikelola Program Studi Farmasi Universitas Adiwangsa Jambi. jurnal ini merupakan media publikasi hasil penelitian dan review artikel pada semua aspek ilmu Farmasi yang bersifat inovatif, kreatif, Original, dan didasarkan pada scientific dalam bidang kajian farmasi klinis komunitas, farmasi bahan alam, kimia farmasi, teknologi farmasi, farmakologi, toksikologi, managemen farmasi, farmasi umum, mikrobiologi farmasi.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 33 Documents
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Pengaruh Intervensi Penyuluhan Terhadap Tingkat Pengetahuan Ibu Tentang Penyakit Kecacingan Di Posyandu Baleagung, Grabag, Magelang Hastuti, Dwii; Yulfatussa’diyah
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 1 No. 2 (2022): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Abstract

Abstract Background: Worms are intestinal parasitic worm infections from the intestinal nematode class that are transmitted through the soil. The prevalence of helminthiasis in the village of Kapoan, Pakis, Magelang found the incidence off egg infection (STH) in vegetables farmers was 0,017% of 60 vegetables farmers. Based on the observations of researches at the research site, there is a lack of knowledege of mothers about the prevention of helminthasis. Objective: to determine the effect of education interventions on the level of mother’s knowledge about the prevention of helminthiasis in Posyandu Baleagung, Grabag, Magelang on February 2022. Method: This researches was conducted using a pre-experimental design method with a one goup pre-test post-test design with a sample of 71 people. Analisis of the data in thi study using SPSS 23. Data analysis was carried out descriptively, then the results obtained were presented in percentages. Results: The results of the researches that were obtained before giving the extension intervention had a good knowledge category of 0%, 59% enough, and 41% less. After giving extension imtervention, there was an increase in the good knowledge category to 87%, 14% emough, and 0% less. Conclusion: there is an effect of education interventions of the knowledge level of the mother on the preventions of worms diseases which can be seen from the results of the Wilcoxon test p (0,000) < 0,05).
Hubungan Tingkat Pendidikan Terhadap Tingkat Pengetahuan Masyarakat Tentang Pengobatan Hipertensi Di Dusun Grojogan Wirokerten Banguntapan Bantul Hastuti, Dwi; Habibah, Khifdiana Rifqi
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 1 No. 2 (2022): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Abstract Background: The prevalence of hypertension has increased according to Riskesdas 2018 data from 25.8% to 34.1%. Data on the health profile of Bantul Regency in 2020, hypertension ranks first out of the top 10 diseases at the Bantul Regency Health Center with a total of 83,932 cases. From some research results show the level of education can increase knowledge about health. Objective: To determine the relationship between education level and community knowledge level about hypertension treatment in Grojogan Wirokerten Village Banguntapan Bantul January 2022 Method: The type of research used is analytic observational with a cross sectional approach. Sampling with purposive sampling technique. The number was calculated using the Slovin formula as many as 96 respondents. The instrument used in this study was a questionnaire, the results of the answers from the questionnaires were assessed after the data was processed and then analyzed using SPSS with kruskal-walls test Results: The results showed that there were 43 respondents with good knowledge (44.80%) and 30 respondents (31.25%) enough, and 23 respondents (23.95%) less. The results of data processing from the kruskal-walls test obtained the Asymp.Sig (2-tailed) value of 0.000 <0.05, which means Ha is accepted, meaning that there is a significant relationship between the level of education and the level of community knowledge Conclusion: There is a relationship between the level of education and the level of public knowledge about the treatment of hypertension
Formulasi Dan Uji Sifat Fisikokimia Sediaan Krim Ekstrak Daun Katuk (Sauropus Androgynous (L.) Merr.) Dengan Variasi Konsentrasi Asam Stearat Artanti, Erin Dwi; Azzahra, Fara
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 1 No. 2 (2022): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Abstract Background: Katuk leaf extract is formulated into a cream preparation to facilitate its use. Cream preparations need a base, the base used is stearic acid with variation concentrations of F1 (10%), F2 (12,5), and F3 (15%). Formulation and evaluation of cream preparations need to ensure that cream preparations have good quality so that their pharmacological effects can be achieved. Objective: The study aims to determine the physicochemical properties of the preparation of katuk leaf extract cream with variations in the concentration of stearic acid. Method: Experimental research using the Posttest Only Design method by testing the physicochemical properties of the cream of katuk leaf extract with variations in the concentration of stearic acid. Results: The result showed that the cream of katuk leaf extract in the 3 formulas was green, had a distinctive smell, was homogeneous, had a slightly thick form at F1 and thick at F2 and F3. The result of the pH values and the diameter of the spread of cream preparations on F1,F2, and F3 respectively were in the range of 7,22 ± 0,04 – 7,15 ± 0,06 and 6,49 ± 0,14 cm - 5,50 ± 0,52 cm. These result meet the requirements of pH and diameter of spread. Conclusion: The conclusion of the study is that the preparation of katuk leaf extract cream with various concentrations of stearic acid met the requirements for physicochemical properties which included organoleptic, homogeneity, pH and diameter of spread. Variations in the concentration of stearic acid affect the diameter of the spread.
Hubungan Tingkat Pengetahuan Dengan Ketepatan Penggunaan Obat Pada Swamedikasi Nyeri Sendi Mutia Rissa, Mexsi
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 1 No. 2 (2022): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Abstract Background: The prevalence according to Basic Health Research data in 2018 states that joint pain problems in Indonesia are 7.3% with a disease ratio of 8.5% in women and 6.1% in men, and the incidence of joint pain problems in Yogyakarta is 5.9 %. Based on the Central Statistics Agency, in 2019 the percentage of the Indonesian population who did self-medication or self-medication was 71.46%. Objective: The purpose of this study was to determine the relationship between the level of knowledge and the accuracy of drug use on joint pain self-medication at the Harapan Sehat Pharmacy for the period of February 2022. Method: The research method used is an analytical observational method with a cross sectional approach, where the researcher makes observations only once at a time. Data collection will be carried out based on a questionnaire that will be distributed to respondents. Data analysis used statistical package for the social science (SPSS) version 25 with chi-square test. Results: The results showed good knowledge of 70 respondents (62%), sufficient knowledge of 22 respondents (20%), and poor knowledge of 20 respondents (18%) with proper use of drugs 104 respondents (93%) and inappropriate use of drugs 8 respondents (7 %). Conclusion: The results of the chi-square test obtained p value = 0.000 <0.05 so it can be concluded that there is a significant relationship between the level of knowledge and the accuracy of drug use.
Evaluasi Penyimpanan Obat di Apotek Kita Kota Jambi Pratama, Septa
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 1 No. 2 (2022): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Background: How medications are stored affects both how well they work as treatments and how safe they are from theft. It should be important to store medications in a way that prevents hazards. The existence of an unsuitable and orderly arrangement of drugs as well as a confined spatial arrangement makes the drugs situated inappropriately based on their place and distribution. The negative impact generated by damaged pharmaceuticals is not just for patients, but also has a consequence on the pharmacy itself. Objective: This study aims to evaluate the drug storage system at Apotek Kita based on the technical guidelines for pharmaceutical standards at the Pharmacy in 2019. Methods: This research is a descriptive observational study, which intends to look at the medication storage system at Apotek Kita. Results: Based on the results of the research conducted, it can be determined that drug storage at Apotek Kita is entirely in accordance with the Technical Guidelines for Pharmaceutical Service Standards at Pharmacies in 2019, as can be seen from the appropriate percentage of 95.65%. Conclusion: The percentage of storage that is suitable for completing appropriate medication storage criteria shows that Apotek Kita has implemented a good medication storage system.
Asam Lemak Omega-3 Dan Hubungannya DenganPenyakit Kardiovaskular Ririn Anjelin; Nadia Raihana; Maimum; Fefri Ferianti; Harry Saputra
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 1 No. 2 (2022): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Cardiovascular diseases are the number one global cause of death, the two most common are coronaryartery disease and stroke. Data suggests that high omega-3 consumption has a benefit in preventingcardiovascular diseases. The report of observations, clinical , animal and in vitro studies havedemonstrated the benefits of omega-3 prevent and treat cardiovascular disease. Although the mechanismis not clear, but it has been shown that the cardiovascularprotection effect of omega-3 fatty acids may becaused by its role influencing biological effects on lipid and lipoprotein metabolism, platelet function,arterial cholesterol distribution, vascular function and inflammatory response.
Analysis of Implementation of Internal Control System in Planning and Budget Implementation at UPTD Puskesmas in Tanjung Jabung Timur District Satria, Darma
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 1 No. 1 (2022): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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This study aims to analyze the implementation of Internal Control System in the planning and implementation of budget, constraints and solutions of the implementation of Internal Control System in the planning and implementation of budget at UPTD Puskesmas in Tanjung Jabung Timur district. The study was conducted at 17 puskesmas by using qualitative descriptive method. Primary data were collected through questionnaires, interviews and observations. Secondary data is collected from relevant documents. The results of the analysis show that budget planning at puskesmas level is good enough. Implementation of Internal Control System in budget planning at UPTD Puskesmas in general is in category quite effective with result of calculation equal to 53,04%. Implementation of BOP activities at UPTD puskesmas is done based on the Plant Of Action that have been prepared and submitted to each program manager. Although in general the application of internal control system in the planning and execution of budget has been running quite effective, but there are still elements of internal control that has not run properly ie the information and communication elements. Information and communication in the planning and implementation of the budget is only 20.59% and 38.24%. This condition is caused by the absence of information technology in planning and budget implementation at UPTD puskesmas.
Pengaruh Ekstrak Daun Teh terhadap Kualitas Motilitas Spermatozoa Mencit Jantan yang Diberi Paparan Asap Rokok Meki Karolina
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 2 No. 2 (2023): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Background: Cigarette smoke exposure is a major contributor to male infertility due to its oxidative stress effects on spermatozoa. Tea leaf extract is known to contain high levels of antioxidants that may counteract these effects. Objective: To determine the effect of tea leaf extract on sperm motility quality in male mice exposed to cigarette smoke. Method: This experimental study used 24 male mice divided into four groups: negative control, cigarette smoke exposure, and two treatment groups receiving cigarette smoke exposure along with 200 mg/kg BW and 400 mg/kg BW of tea leaf extract. Sperm motility was assessed using microscopic examination after 14 days of treatment. Results: The group exposed to cigarette smoke alone showed significantly decreased sperm motility. Administration of tea leaf extract at both doses improved sperm motility, with the 400 mg/kg BW group showing a motility value close to the negative control. Conclusion: Tea leaf extract significantly improves sperm motility in mice exposed to cigarette smoke, likely due to its antioxidant content.
Uji Efektifitas Daun Kemangi (Ocium basilicum L.) Terhadap Pertumbuhan Bakteri Staphylococcus aureus Antonius Fransiskus Putra Meliala
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 2 No. 2 (2023): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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The present study investigates the antibacterial efficacy of basil leaves (Ocimum basilicum L.) against the growth of Staphylococcus aureus, a Gram-positive bacterium responsible for various human infections. The increasing resistance of S. aureus to conventional antibiotics has necessitated the exploration of plant-based alternatives with potential antimicrobial activity. Basil leaves are known to contain active phytochemical constituents such as flavonoids, tannins, saponins, and essential oils that may contribute to antibacterial properties. An experimental laboratory study was conducted using a completely randomized design, employing various concentrations of basil leaf extract (10%, 20%, 40%, 80%) tested against S. aureus through the disc diffusion method. Chloramphenicol was used as the positive control, and sterile distilled water as the negative control. The results demonstrated a concentration-dependent antibacterial activity, with the 80% extract exhibiting the largest inhibition zone, though still lower than the zone produced by chloramphenicol. The data were analyzed using one-way ANOVA followed by post hoc Tukey test, indicating significant differences (p < 0.05) among the treatment groups. The findings confirm that basil leaf extract possesses antibacterial activity against Staphylococcus aureus, supporting its potential as a natural antimicrobial agent. These results offer preliminary evidence for the development of phytotherapeutic alternatives in combating bacterial infections, particularly in light of rising antibiotic resistance.
Aktivitas Anti Helmintik Infusa Biji Pepaya (Carica papaya L.) terhadap cacing Ascaris suum (studi in Vitro) Edwin Lewis
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 2 No. 2 (2023): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Ascaris suum infection remains a significant problem in both veterinary and human health, particularly in areas with poor sanitation. The use of synthetic anthelmintics faces challenges such as resistance and adverse side effects, prompting the search for alternative treatments from natural sources. This study aimed to evaluate the anthelmintic activity of papaya (Carica papaya L.) seed infusion against Ascaris suum through an in vitro approach. Papaya seeds were dried, ground, and extracted using hot water infusion at 90°C. The assay involved immersing A. suum worms in various infusion concentrations (10%, 20%, 30%, and 40%) and observing them at 1, 3, and 6-hour intervals to determine paralysis and mortality times. The results showed that papaya seed infusion exhibited significant concentration- and time-dependent anthelmintic activity. The 40% concentration produced the strongest effect, causing paralysis within 1 hour and mortality within 3 hours. This activity is likely due to the presence of alkaloids, carpaine, flavonoids, and tannins in papaya seeds, which are toxic to the neuromuscular system of the worms. It can be concluded that Carica papaya seed infusion has potential as a natural anthelmintic agent against Ascaris suum.

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