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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 1,093 Documents
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Bentonite as an Adsorption Surface for Bromothymol Blue Dye from Aqueous Solution Kawther Ahmed Sadiq
Journal of Global Pharma Technology Volume 11 Issue 04.
Publisher : Journal of Global Pharma Technology

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Abstract

Accomplishment of Adsorption of dye from aqueous solution on the surface of bentonite was done under the following optimized conditions: temperature, initial concentration, contact time and weight surface. Via utilizing the technique of UV-Vis spectophotometry at (λmax= 432 nm) the quantitative estimation of the dye adsorption has been performed. this study has demonstrated that the more increasing of  adsorption with the more increasing of temperature from 25 ˚C to 45 ˚C also increasing of clay weight (0.1-1.1 g).calculating thermodynamic parameters like change in the free energy (∆G), the enthalpy (∆H), the entropy (∆S). Results of adsorption isotherms obtained in this study were inconsitence with fitted with Freund lich adsorption isotherm.Keywords: Adsorption, Bentonite, Bromothymol blue.
Latent Membrane Protein 1 Gene of Epstein - Barr virus: 30-Base-Pair Deletion in Indonesian Nasopharyngeal Carcinoma Patients Yurnadi Hanafi Midoen
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Abstract

Introduction: Epstein Barr Virus (EBV), a member of the Herpesviridae family, is a dsDNA virus. Nasopharyngeal carcinoma (NPC) patients express EBV latent genes EBERs, EBNA1, LMP1, LMP2A, and LMP2B. The LMP1 gene, in particular, plays important roles in epithelial oncogenesis and B-lymphocyte transformation. Several epidemiological studies found a specific variant of LMP gene detectable as a 30-bpdeletion in NPC patients and it is still unclear whether this deletion is associated with NPC pathogenesis in Indonesian population. The aim of this research is to understand the existence of the deletion of the 30-bp LMP1 gene in Indonesian NPC patients and to determine the frequency of 30-bp deletion of LMP1 gene and its association with the pathological status. Methods: The 30-bp deletion in LMP1 gene was identified by nested PCR and subsequent electrophoresis in 2% agarose gel. The results were determined as 162-bp DNA band of the LMP1 gene (without 30-bp deletion) and 132-bp DNA band of the LMP1 gene (with 30-bp deletion). Results: Among 100 identified samples from Jakarta, 8 samples were found to have the 30-bp deletion, 71 samples did not have 30-bp deletion and 21 samples carried coexistence variants. Conclusion: In Indonesia, especially in Jakarta, EBV variant of 30-bp deletion of LMP1 gene was found at low frequency (8%) in comparison with variant without deletion (71%). There is a variant of LMP1 gene mixtures (21% coexistence with and without deletion). Analysis of data using Fisher's exact test shows that there is no significant relationship between 30-bp deletion of LMP1 gene and NPC pathological status (p> 0.05).Key words: 30-bp deletion, NPC, EBV, LMP1, Coexistence
Telemedicine Medical Image Compression based on ROI (A Case Study of Spine Medical Images) Abd Abrahim Mosslah
Journal of Global Pharma Technology .
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Abstract

In recent years, telemedical need arose, as a result of the increasing numbers of patients significantly, where using image compression is one of the most important techniques in the field processing research field, as well as in multiple applications such as medicine, reconnaissance, aerial surveillance, and space. Image compression necessary to reduce transport costs due to rising transport prices and distances In this method, we divide the original image into two separate sub-images called ROI and non-ROI. Region of interest (ROI) is the decisive area in a medical image, which is very important. This area may indicate a disease and must result in a right diagnosis. We use the spread spectrum-embedding algorithm to embed a binary mark into DCT transform of non-ROI part of an image.  In this search review the compression of the medical images and encoded and then decoder with no distort medical images was taken for sections of the spine for sick people.  Used in the field of telemedicine, Medical images encoded works with LSK through use WT (wavelet transform), During the user interaction (encryption) obtained of the ROI regions that lead us to get high compression ratio.The method used in this technology decompress on the block and like-minded countries on the basis of the value stored, note that the time of implementation of this method is low when compared with other methods.Keywords: Telemedicine, Medical Image Compressing, ROI, fractal image compression, LSK.
Knowledge, Awareness and Practices Regarding Dengue Fever among the Rural and Urban Populations of Salem District Mohamed Yasir Arafath
Journal of Global Pharma Technology Volume 11 Issue 03 (2019) March. 2019
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Abstract

Objective: The objectives of the study were to assess how many people have knowledge and level of awareness on dengue, to know about most prevalent preventive measure, to ascertain the source of information regarding dengue and to enquire about the diagnostic measures and treatment strategies used by affected individuals.Methods: A cross-sectional observational study was conducted on 1000 respondents in Rural and Urban areas of Salem district, Tamilnadu to evaluate the knowledge, awareness and practices regarding dengue fever.Results: The results showed that only 52% of the rural respondents and 96% of urban respondents were aware about dengue fever.53% of the rural respondents and 97% urban respondents identified the vector as mosquito. The overall knowledge of dengue specific symptoms was much lower, in rural as compared to urban areas. The knowledge about the preventive measures was inadequate among the rural respondents when compared to that of urban respondents. Majority of the rural respondents (30%) had no source of information about dengue fever. While among the urban respondents, 29% had information about dengue fever from T.V/radio.Conclusion: The overall knowledge, awareness and practices regarding dengue fever were found to be inadequate among the rural populations when compared to urban populations. There is a need to make rural people aware of different preventive practices and reduce this knowledge application gap.Keywords: Dengue Fever; Knowledge; Awareness; Practices; Rural; Urban
Probiotics - A Review Kamala Kumari
Journal of Global Pharma Technology Volume 13 Issue 02 (2021) Feb. 2021
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Abstract

Probiotic bacteria are defined as live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. While this beneficial effect was originally thought to stem from improvements in the intestinal microbial balance, there is now substantial evidence that probiotics can also provide benefits by modulating immune functions. Scientists continue to work on elucidation of the mechanisms of the most common probiotic strains. The results that might arise from could be extremely important because the use of probiotics to maintain health must be considered promising, although much remains to be elucidated. The universal use of some strains seems less reasonable from an ecological point of view than selection of strains from their natural habitat were they are adapted to the ecological niche. It is important to understand that all probiotic strains are unique and different and their properties and characteristics should be well defined.
Effectiveness of Impulse Control Training in Self-Efficacy of High School Students Shahrbanoo Ghahari
Journal of Global Pharma Technology .
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Abstract

Introduction and Objective impulsive behaviors are dysfunctional behaviors that harm others; hence, it is essential to teach some methods to control impulses. In this regard, this study was conducted to examine effectiveness of impulse control training on self-efficacy among high school students. Materials and Methods this is an experimental with pretest-posttest plan. Statistical population of study consisted of all students educating at first grade of high school in Roodsar, Iran; in this regard, 60 students that were not able to control impulse were selected as sample size form several schools through purposeful method then were assigned into two 30-members groups (control and experimental). Then, Sherer Self-efficacy Questionnaire was distributed among members in both groups within pretest then experimental groups received the protocol of impulse control training and control group remained in waiting list; ultimately, self-efficacy questionnaire was again distributed among members in both groups to examine effect of impulse control training protocol as posttest. The obtained data were analyzed using ANCOVA through SPSS22 Software. Findings the obtained results showed that impulses control training could affect self-efficacy of students (P<0.005). Conclusion it is concluded in accordance with obtained findings that impulse control training can increases self-efficacy among students.Keywords: Impulse Control, Self-Efficacy, High School Students.
Effectiveness of Edible Coating, Preservation Temperature and Packaging to the Rancidity and Proteolytic Activity in Dried Mudskipper (Pseudapocryptes Elongatus) Nguyen Phuoc Minh
Journal of Global Pharma Technology Volume 11 Issue 04.
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Abstract

Mudskipper (Pseudapocryptes elongatus) has become a high value species in the markets of Mekong Delta, Viet Nam. Mudskipper aquaculture has potential for coastal aquaculture development and is an alternative to shrimp farming in the Mekong Delta. In terms of nutritional quality of fish, sometimes dry fish have higher quality standards compared to fresh fish. P. elongatus aquaculture has developed rapidly to supply the high demand of domestic consumers. Consumption of dried mudskippers fishes has increased during recent years as consumers have become more aware of its nutritional benefits and of the health concerns associated with other meat products. However the dry-salted mudskippers are not stable at normal preservation by rancidity and proteolytic activity because they have too much oil as well as protease enzyme in their abdomen. Edible coating provide a replacement and fortification of the natural layers at the product surfaces to prevent moisture losses, gas aromas and solute movements out of the food, while selectively allowing for controlled exchange of important gases. Biodegradability, barrier properties, biocompatibility, and edibility as well as being nontoxic and non-polluting are a few advantages of edible films and coatings over plastic packages. Preservation temperature and packaging method also influenced to rancidity and proteolytic activity in the dried mudskippers (Pseudapocryptes elongatus). Objective of the current research studied the feasibility of sodium alginate coating in preservation of dried mudskipper (Pseudapocryptes elongatus). The dried mudskippers were treated by different concentration of sodium alginate (1.0%, 1.5%, 2.0%, 2.5%, 3. 0%). The effectiveness of sodium alginate coating was based on quality changes of dried mudskippers such as lipid oxidation: Peroxide value (mEqO2/ kg), Thiobarbituric acid (mg maloaldehyde/ kg); proteolytic changes: total volatile base (TVB-N, mg N/100 g) nitrogen content and trimethylamine (TMA, mg N/100 g). All treated samples were monitored during 12 months of storage at ambient temperature in 3 months of interval sampling. Results revealed that the coating of 2.5% w/w sodium alginate, 4oC in vaccum bag could control microbial spoilage and lipid oxidation of the dried mudskippers. By this approach, the dried mudskippers (Pseudapocryptes elongatus) are stable at normal environment for 12 months. The study indicated that the edible coating could be commercially utilized to prolong the shelf‐life of this oil fish. The improvement in the quality of the seafood products is achieved through inhibition of proteolytic reaction, reduction of lipid oxidation reduction and enhancement of sensorial attributes. Keywords: Pseudapocryptes elongatus, Sodium alginate, Proteolytic reaction, Lipid oxidation, Shelf-Life.
Immunomodulator Activity and Antirheumatoid Arthritis Extract of Ethyl Acetate Ginseng Bugis Talinum Paniculatum (jacq.) Gaertn) Andi Emelda
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
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Abstract

The Immunomodulator is one of the compounds that can improve immune system. Chemical compounds work through the immune system to prevent and treat disease. Rheumatoid arthritis is an autoimmune disease that is chronic-systemic inflammation. The purpose of this study was to determine the effects of imonomodulator and antirheumatoid arthritis of ethyl acetate extracts of ginseng bugis leaves (Talinum Paniculatum (Jacq.) Gaertn). This study was divided into 2 groups, namely the immunomodulatory testing using sheep red blood cells and CFA-induced antirhematoid. This study used wistar rats which divided into 6 groups for immunomodulatory activity and 5 groups for antirematoid arthritis. The dose of ethyl acetate extract used was 0.05 g/KgBW; 0.1 g/KgBW, and 0.15 g/KgBW. Statistical test results for immunomodulatory activity showed significantly different results between the extract group doses of 0.05 g/KgBW; 0.1 g/KgBW, and 0.15 g/KgBW (p <0.05) with a negative control group. Rheumatoid arthritis testing showed (p <0.05) to the foot volume and arthritis index. The results showed that ethyl acetate extract of ginseng bugis leaves have immunomodulatory and antirheumatoid arthritis activity.Keywords: Immunomodulator, Anti Rheumatoid arthritis, Ethyl acetate, Talinum Paniculatum (Jacq.) Gaertn.
Constant Attention and its Correlation with Case Anxiety for Students of the Faculty of Physical Education and Sports Sciences Jameel Hamid Kadhim
Journal of Global Pharma Technology .
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Abstract

Students' responses to rapid and changing situations need to be swift, predictable, well-behaved, and control over different attitudes in the course of a lesson, based mainly on higher mental processes (such as attention, perception, perception, thinking and sense). The objective of the search is to learn about the correlation between the constant attention and the anxiety of the case for the students of the Faculty of Physical Education and Sports Sciences for the academic year 2017-2018. The researchers use the descriptive method in the relational relationships to fit and the nature of the search procedures. the research community is the fourth-stage students at the Faculty of Physical Education and Sports Sciences/University of Babylon, of which there are 120 students, while the research sample was the fourth phase students of the (60) divisions (C,D), who were randomly selected from the research community. Through the collection of data and the results obtained, researchers have reached the following conclusions:Students owning a moderate level of attention and anxiety caseHaving a significant correlation between the anxiety of the case and the attention of the research sample.Keywords: Constant attention, Case anxiety and Sports Sciences.
Comparison of the Training Skills of the Handball Trainers for the First and Second Classes in Iraq Ahmed Kadhim Abdulkareem
Journal of Global Pharma Technology Volume 11 Issue 6.
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Abstract

The research consisted of two axes: the level of communication skills and their comparison among the handball trainers for the category of applicants in Iraq. The training communication skills standard was developed and the descriptive method was used in a comparative manner to suit the nature of the research. The research sample included (20) trainers, and the comparisons between training skills were obtained using statistical means.Keywords: Training skills and handball trainers.

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