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Triple elimination screening for pregnancy: study at Dokter Soekardjo Hospital Desy Aprianti; Susanti Ratunanda
ACTA Medical Health Sciences Vol. 3 No. 1 (2024): Acta Medical and Health Sciences
Publisher : ACTA Medical Health Sciences

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Triple Elimination is an initiative that supports the eradication of mother-to-child transmission of three infectious diseases: HIV, syphilis, and hepatitis B. Common tests for this initiative include anti-HIV, RPR-TP, and HBsAg rapid screenings. This descriptive study aimed to determine the results of these screenings in pregnant women at Dokter Soekardjo Hospital. We used a total sampling method to include a total of 182 pregnant women who met the inclusion criteria. The findings revealed that the majority of pregnant women were in early adulthood (26-35 years) and late adulthood (36-45 years), each comprising 32.96%. Most subjects were housewives (84.61%) who had a senior high school education (38.46%) , and were examined during their third trimester (58.80%). The RPR-TP rapid screening showed reactive results in 7 women (3.84%). No reactive results were found for Anti-HIV, while one woman (0.54%) tested reactive for HBsAg. The third trimester detected the most reactive results, with 6 women showing reactivity: 5 (4.675%) for RPR-TP and 1 (0.93%) for HBsAg. Despite the absence of reactive Anti-HIV results, precautions against HIV transmission during pregnancy are crucial due to the risk of placental infection or damage. The study's RPR-TP results highlight the importance of addressing reactive cases, given their potential impact. Additionally, performing HBsAg tests remains critical due to the risk of chronic HBV infection in babies. DOI : 10.35990/amhs.v3n1.p1-11 REFERENCES Mardiyanti I, Rahayu EP, Zuwariah N, Winoto PMP, Karmila HN. The effectiveness of triple elimination examination (HIV, syphilis, hepatitis), roll over test (ROT) and mean arterial pressure (MAP) and self-hypnosis on emergency management of high-risk pregnant women during pandemic. Bali Medical Journal. 2023 Aug 1;12(2):1995–1997. Wu S, Wang J, Guo Q, Lan H, Sun Y, Ren M, et al. Prevalence of human immunodeficiency virus, syphilis, and hepatitis B and C virus infections in pregnant women: a systematic review and meta-analysis. Clinical Microbiology and Infection. 2023 Aug;29(8):1000–1007. Cohn J, Owiredu MN, Taylor MM, Easterbrook P, Lesi O, Francoise B, et al. Eliminating mother-to-child transmission of human immunodeficiency virus, syphilis and hepatitis B in sub-Saharan Africa. Bulletin of the World Health Organization. 2021 Apr 1;99(4):287–295. Bell L, van Gemert C, Allard N, Brink A, Chan PL, Cowie B, et al. Progress towards triple elimination of mother-to-child transmission of HIV, hepatitis B and syphilis in Pacific Island Countries and Territories: a systematic review. Lancet Regional Health – Western Pacific. 2023 Jun;35:100740. Pijoan DI, Jambi M, Herlambang H, Kusdiyah E, Syauqy A, Fitri AD, et al. Peningkatan Pengetahuan Tentang Triple Elimination. Peraturan Menteri Kesehatan Republik Indonesia No. 52 Tahun 2017. Justiz Vaillant AA, Gulick PG. HIV Disease Current Practice. In: StatPearls. 2020. World Health Organization. HIV and AIDS [Internet]. 2023 [cited 2023 Nov 9]. Available from: https://www.who.int/news-room/fact-sheets/detail/hiv-aids Peeling RW, Mabey D, Kamb ML, Chen XS, Radolf JD, Benzaken AS. Syphilis. Nature Reviews Disease Primers. 2017 Oct 12;3(1):17073. World Health Organization. Syphilis [Internet]. 2023 [cited 2023 Nov 8]. Available from: https://www.who.int/news-room/fact-sheets/detail/syphilis Tripathi N, Mousa OY. Hepatitis B. In: StatPearls [Internet]. 2023 [cited 2023 Nov 8]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK555945/ World Health Organization. Hepatitis B [Internet]. 2023 [cited 2023 Nov 8]. Available from: https://www.who.int/news-room/fact-sheets/detail/hepatitis-b Pedoman Penilaian Alat Kesehatan dan PKRT. Kementerian Kesehatan Republik Indonesia; 2018. Ratih WU. Strategi Pemeriksaan Laboratorium Anti-HIV. Jurnal Farmasi Sains dan Komunitas. 2012;11(2):98–103. Liazmi MC. Hubungan Antara Orientasi Seksual dan Penggunaan Napza Suntik Dengan Kejadian Sifilis pada Pasien HIV/AIDS di RSUD Dr. H. Abdul Moeloek Lampung Tahun 2017–2019. [Lampung]: Universitas Lampung; 2020. Satyaputra F, Hendry S, Braddick M, Sivabalan P, Norton R. The laboratory diagnosis of syphilis. Journal of Clinical Microbiology. 2021 Sep 20;59(10). Mehta P, Grant LM, Reddivari AKR. Viral Hepatitis. [Updated 2024 Mar 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554549/ Abaalkhail F, Al-Hamoudi W, Khathlan A, Alghamdi S, Alghamdi M, Alqahtani S, et al. SASLT practice guidelines for the management of Hepatitis B virus – An update. Saudi Journal of Gastroenterology. 2021;27(3):115. Al Amin M. Klasifikasi Kelompok Umur Manusia Berdasarkan Analisis Dimensifraktal Box Counting dari Citra Wajah dengan Deteksi Tepi Canny. MATHunesa: Jurnal Ilmiah Matematika. 2017. Yanti NID, Krisnana I, Lestari P. Hubungan Tingkat Pendidikan dengan Kepatuhan Antenatal Care pada Primigravida Riwayat Pernikahan Dini. Indonesian Midwifery and Health Sciences Journal. 2021 Jun 23;3(2):98–106. Primayanti I, Danianto A, Jumsa R, Geriputri NN, Andari MY. Gambaran Epidemiologi Faktor Risiko Preeklamsia pada Ibu Hamil. Jurnal Kedokteran Unram. 2022;1:785–788. Brunner L, Chagnon Krief P, Probst I, Abderhalden-Zellweger A, Renteria SC, Vonlanthen J, et al. A narrative review on factors associated with job interruption during pregnancy. International Journal of Occupational Medicine and Environmental Health. 2023 Sep 7;36(3):303–323. Peraturan Menteri Kesehatan Republik Indonesia No. 52 Tahun 2017. Gonçalves B, Ferreira C, Alves CT, Henriques M, Azeredo J, Silva S. Vulvovaginal candidiasis: Epidemiology, microbiology and risk factors. Critical Reviews in Microbiology. 2016 Nov 21;42(6):905–927. Widhyasih RM, Geni L, Fauziah PN, Amalia V. Gambaran Hasil Pemeriksaan Skrining RPR-TP Rapid, Anti-HIV dan HBsAg Pada Ibu Hamil di Puskesmas Kecamatan Ciracas. Jurnal Ilmiah Analis Kesehatan. 2020;6(1):82–90. Domingues RMSM, Szwarcwald CL, Souza Junior PRB, Leal M do C. Prevalence of syphilis in pregnancy and prenatal syphilis testing in Brazil: Birth in Brazil study. Revista de Saúde Pública. 2014 Oct;48(5):766–774. Kresno SB. Diagnosis dan Prosedur Laboratorium. Fakultas Kedokteran Universitas Indonesia; 2010. Han GR. Management of chronic hepatitis B in pregnancy. World Journal of Gastroenterology. 2012;18(33):4517. Armini LN, Setiawati EP, Arisanti N, Hilmanto D. Evaluation of Process Indicators and Challenges of the Elimination of Mother-to-Child Transmission of HIV, Syphilis, and Hepatitis B in Bali Province, Indonesia (2019–2022): A Mixed Methods Study. Tropical Medicine and Infectious Disease. 2023 Nov 3;8(11):492.

A qualitative, phenomenological study of scabies patients at Cikatomas Health Center Desy Linasari; Sylvia Mustika Sari; Selly Andriani; Ris kristiana; Henny Juliastuti
ACTA Medical Health Sciences Vol. 3 No. 1 (2024): Acta Medical and Health Sciences
Publisher : ACTA Medical Health Sciences

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Infestation with the Sarcoptes scabies mite causes scabies, an infectious skin disease that is often found in densely populated areas. This disease is characterized by itching, especially at night, as well as the appearance of rashes and lesions on the skin. Scabies is an endemic public health problem that attacks groups of people with poor personal hygiene. This research aims to understand the experiences of scabies patients regarding their disease journey, including treatment and prevention efforts. The research method used is qualitative with a phenomenological approach. Participants were selected using purposive sampling, and a total of seven participants from Cikatomas Health Center, Tasikmalaya Regency, were included. We collected data through in-depth interviews. From the research results, five themes emerged regarding the experiences of scabies patients in their disease journey: symptoms, risk factors, chain of transmission, treatment efforts, and prevention efforts. In conclusion, during the onset of symptoms, patients reported experiencing intense itching, particularly, in several areas of the body. The most prominent risk factors found in patients were poor personal hygiene and inadequate housing density. The chain of transmission occurred due to contact with other scabies patients, including a history of sharing beds in dormitories and using shared items. Patients sought treatment at health facilities, but did not receive treatment together with friends or other affected family members, thereby allowing the chain of transmission to continue. Prevention efforts have been made by improving personal hygiene. DOI : 10.35990/amhs.v3n1.p12-23 REFERENCES Sungkar S. Skabies: Etiologi, Patogenesis, Pemberantasan dan Pencegahan. Jakarta: Badan Penerbit Fakultas Kedokteran Universitas Indonesia; 2016. Djuanda A, Suriadiredja ASD, Sudharmono A. Ilmu Penyakit Kulit dan Kelamin. Edisi ke-7. Jakarta: Badan Penerbit Fakultas Kedokteran Universitas Indonesia; 2016. Marga P. Pengaruh personal hygiene terhadap kejadian penyakit skabies. J Ilm Kesehatan Sandi Husada. 2020;9(2):773–8. Leung A, Lam J, Leong K. Scabies: A neglected global disease. Curr Pediatr Rev. 2020;16(1):33–42. World Health Organization. Scabies. Geneva: WHO; 2020 [cited 2023 Nov 8]. Available from: https://www.who.int/news-room/fact-sheets/detail/scabies El-Moamly AA. Scabies as part of the WHO roadmap for neglected tropical diseases 2021–2030: What we know and what we need to do for global control. Trop Med Health. 2021;49(1):1–11. Wibianto A, Santoso I. Prevalensi penderita skabies di Puskesmas Ciwidey, Jawa Barat (2015–2020): Studi retrospektif. 2020;1:281–90. Kumarayanti NKD, Hapsari Y, Kusuma DR. Penatalaksanaan skabies dengan pendekatan kedokteran keluarga pada pasien dewasa. J Kedokt. 2020;9(2):220–8. Dinas Kesehatan Jawa Barat. Profil Kesehatan Kabupaten Tasikmalaya 2019. Bandung: Dinkes Jabar; 2019. Available from: https://dinkes.jabarprov.go.id/ Kurniawan M, Sie M, Ling S. Diagnosis dan terapi skabies. Cermin Dunia Kedokteran. 2020;47(2):104–7. Tanto C, Liwang F, Hanifati S. Selekta Kedokteran. Edisi IV Jilid 1. Jakarta: Media Aesculapius; 2016. p. 311–2. Rofifah TN, Budi U. Hubungan sanitasi asrama dan personal hygiene santri dengan kejadian scabies di Pondok Pesantren Al Ikhsan, Banyumas. 2019;38(1):1–23. Suciaty S, Ismail S. Profil penyakit skabies di wilayah kerja Puskesmas Kamonji tahun 2018. Medika Alkhairaat. 2021;3(2):45–50. Naftass Z, Putri TR. Hubungan jenis kelamin, tingkat pendidikan, dan pengetahuan terhadap kejadian skabies pada santri Pondok Pesantren Qotrun Nada, Depok. 2018;10(2):115–9. Muslih R. Hubungan personal hygiene dengan kejadian skabies pada santri Pondok Pesantren Cipasung, Tasikmalaya. Tasikmalaya: Fakultas Ilmu Kesehatan Universitas Siliwangi; 2012. Mutiara H, Syailindra F. Skabies. Med J Lampung Univ (MAJORITY). 2016;5(2):37–42. Handari, Yamin M. Analisis faktor kejadian skabies di Pondok Pesantren An-Nur, Ciseeng, Bogor. J Kedokt dan Kesehatan. 2018;14(2):74–82. Purwanto H, Hastuti RP. Faktor risiko penyakit skabies di masyarakat. J Kesehatan. 2020;11(1):145–50. Mading M, Bule Sopi I. Kajian aspek epidemiologi skabies pada manusia. J Penyakit Bersumber Binatang. 2019;2(2):9–17. Rosumeck S, Nast A, Dressler C. Ivermectin and permethrin for treating scabies (review). Cochrane Library. 2018:60–4. Gunning K, Kiraly B, Pippitt K. Lice and scabies: Treatment update. Am Fam Physician. 2019;99(10):635–42.

Erythrocyte sedimentation rate in new cases of pulmonary tuberculosis patients Marlina Wijayanthy; Susanti Ratunanda
ACTA Medical Health Sciences Vol. 3 No. 1 (2024): Acta Medical and Health Sciences
Publisher : ACTA Medical Health Sciences

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This study focuses on the significant health issue of tuberculosis (TB), with Indonesia ranking as the second-highest country worldwide in TB incidence. Diagnostic advancements, including the Rapid Molecular Test (RMT), such as GeneXpert MTB/RIF Ultra, have been pivotal in identifying TB cases. In pulmonary tuberculosis, the Erythrocyte Sedimentation Rate (ESR) reveals an inflammatory process marked by elevated fibrinogen and plasma globulin levels linked to acute-phase reactions. This research, conducted at Waled Regional General Hospital, employs a quantitative descriptive approach with purposive sampling. Data on patient characteristics, new pulmonary TB cases, and ESR results are extracted from medical records, covering the period from January to June 2023. Among the 66 patients who meet the inclusion criteria, the majority (74.2%) belong to the adult age group, with males comprising 68.2%. ESR elevation is observed in 87.9% of cases, averaging 78.3 mm/hour, ranging from 5 to >140 mm/hour. ESR increase is prominent in adult males (83.7%), possibly linked to their higher daily activity and social interactions, enhancing exposure to Mycobacterium tuberculosis. Furthermore, ESR elevation in adult males may be attributed to a higher likelihood of smoking and alcohol consumption, potentially diminishing macrophage, CD4+, CD8+, and T cell activities and consequently intensifying inflammatory processes. This research sheds light on the prevalence and factors contributing to pulmonary tuberculosis, providing valuable insights for targeted interventions and public health strategies. DOI : 10.35990/amhs.v3n1.p24-30 REFERENCES Kementerian Kesehatan Republik Indonesia. Tatalaksana Tuberkulosis: Pedoman Nasional Pelayanan Kedokteran. Jakarta; 2020. Dinas Kesehatan Jawa Barat. Jumlah Kasus Penyakit Tuberkulosis Berdasarkan Kabupaten/Kota di Jawa Barat [Internet]. 2021 [cited 2023 Oct 5]. Available from: https://opendata.jabarprov.go.id/id/dataset/jumlah-kasus-penyakit-tuberkulosis-berdasarkan-kabupatenkota-di-jawa-barat Silvia H, Mellysa R, Citra T. Perbandingan nilai laju endap darah (LED) antara metode Westergren dengan metode mikro ESR pada penderita tuberkulosis paru. Jurnal Medikes. 2018;5(2):182. Sulochana S, Gayathri, Siddartha JR, Fathima J. Clinical significance of erythrocyte sedimentation rate in tuberculosis. Res J Pharm Technol. 2022;15(1):245–9. Kasih KN, Sulastina NA. Analisis laju endap darah pada pasien tuberkulosis paru. J 'Aisyiyah Medika. 2019;4:44–52. Pratiwi CD, Puspitasari E, Nurohmah V. Deskripsi jumlah leukosit dan laju endap darah pada pasien tuberkulosis di RS Paru Dungus Madiun. Borneo J Med Lab Technol. 2019;2(1):92–6. Kementerian Kesehatan Republik Indonesia. Kebijakan Program Nasional Penganggulangan TB dalam Penggunaan TCM: Petunjuk Teknis Pemeriksaan TB Menggunakan Tes Cepat Molekul. Novianti, Simarmata OS, Lolong DS. Pemanfaatan Tes Cepat Molekuler (TCM) sebagai alat diagnostik TB paru di RSUD Wangaya Kota Denpasar. Jurnal Kesehatan. 2019;18(3):135–48. Atherton RR, Cresswell FV, Ellis J, Kitaka SB, Boulware DR. Xpert MTB/RIF Ultra for tuberculosis testing in children: a mini-review and commentary. Front Pediatr. 2019;7:1–7. Sava C, Sava M, Drăgan AM, Iuhas A, Niulaș L, Marinău CP, et al. The use of Xpert MTB/RIF Ultra testing for early diagnosis of tuberculosis: A retrospective study from a single-center database. J Clin Tuberc Other Mycobact Dis. Kementerian Kesehatan Republik Indonesia. Petunjuk Teknis Tatalaksana Tuberkulosis Anak dan Remaja Indonesia. Kementerian Kesehatan Republik Indonesia. Pedoman Nasional Pelayanan Kedokteran: Tatalaksana Tuberkulosis. Zaporojan N, Negrean RA, Hodișan R, Zaporojan C, Csep A, Zaha DC. Evolution of laboratory diagnosis of tuberculosis. J Clin Med. Kementerian Kesehatan Republik Indonesia. Laporan Program Penanggulangan Tuberkulosis Tahun 2022. Listiyowati T, Wardani D, Sudarsono TA, Wijayanti L. Relationship between result of GeneXpert RT-PCR and erythrocyte sedimentation rate in suspected tuberculosis patients. J Ilmu dan Teknologi Kesehatan. 2023;10(2):259–67. Kumar A, Dutta A, Prasad A, Jain M. Survey of changes in the erythrocyte sedimentation rate at different stages of therapy by Westergren method in pulmonary tuberculosis patients in Malwa region, India. Int J Physiol. 2019;7:1–5. Ningrum WL. Profil laju endap darah pada pasien tuberkulosis kasus baru di RSU Kota Tangerang Selatan. [Skripsi]. Jakarta: Universitas Islam Negeri Syarif Hidayatullah; 2017. Bashir AB, et al. Reactive thrombocytosis and erythrocyte sedimentation rate in patients with pulmonary tuberculosis. J Med Lab Diagn. 2014;5(3):29–34. Martins C, Gama AC, Valcarenghi D, Batschauer A. Markers of acute-phase response in the treatment of pulmonary tuberculosis. J Bras Patol Lab. 2014;50:428–33. Alende-Castro V, Alonso-Sampedro M, Vazquez-Temprano N, Tuñez C, Rey D, García-Iglesias C, et al. Factors influencing erythrocyte sedimentation rate in adults: new evidence for an old test. BMC Med.

Overview of rapid molecular test (RMT)–gene xpert mtb/rif ultra results in pulmonary tuberculosis patients based on the history of therapy Balada A Nurinsani; Susanti Ratunanda
ACTA Medical Health Sciences Vol. 3 No. 1 (2024): Acta Medical and Health Sciences
Publisher : ACTA Medical Health Sciences

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Tuberculosis (TB) is a health threat that remains a problem both globally and nationally. Indonesia has the world’s second highest number of TB cases. Various examination methods were developed for detecting this disease; one of the most developed is the Rapid Molecular Test (RMT). This study aims to describe the results of a rapid molecular test (GeneXpert) using the Xpert MTB/RIF Ultra tool in pulmonary tuberculosis based on a treatment history consisting of new cases, relapse cases, and drug withdrawal cases. The study subjects were 47 patients with pulmonary tuberculosis at Puskesmas Ciwidey, Bandung Regency Health Office, from February to September 2023. The results showed that characteristics of respondents were male (57.4%), female (42.6%), and mostly were aged between 20 and 44 years (53.1%). These results are in line with previous research. The majority of cases (87.2%) were new cases and the most RMT examination results indicated that MTB detected rifampicin sensitivity (78.7%). In new cases, MTB-detected rifampicin sensitivity at 78.1%, MTB-not detected at 19.5%, and MTB-detected rifampicin resistance at 2.4%. In relapse cases, all respondents (100%) showed MTB detected to be rifampicin-sensitive. In drug withdrawal cases, MTB detected 75% rifampicin sensitivity and 25% rifampicin resistance. The results of this study indicate that one possible factor in the occurrence of germ resistance to antituberculosis drugs is inadequate treatment of TB patients, in this case drug withdrawal cases. DOI : 10.35990/amhs.v3n1.p31-39 REFERENCES Kementerian Kesehatan Republik Indonesia. Tuberkulosis Paru. Pedoman Nasional Pelayanan Kedokteran Tatalaksana Tuberkulosis. 2020; p10–26. World Health Organization. Tuberculosis Incidence. [Internet]. Available from: https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2022/tb-disease-burden/2-1-tb-incidence Kementerian Kesehatan Republik Indonesia. Petunjuk Teknis Pemeriksaan TB Menggunakan Tes Cepat Molekular. 2017; p4–126. Shapiro AE, Ross JM, Yao M, Schiller I, Kohli M, Dendukuri N, et al. Xpert MTB/RIF and Xpert Ultra assays for screening for pulmonary tuberculosis and rifampicin resistance in adults, irrespective of signs or symptoms. Cochrane Database Syst Rev. 2021;3:1–82. doi:10.1002/14651858.CD013694.pub2 Kementerian Kesehatan Republik Indonesia. Pedoman Nasional Pelayanan Kedokteran Tatalaksana Tuberkulosis. 2019; p9–23. Dorman SE, Schumacher SG, Alland D, Nabeta P, Armstrong DT, King B, et al. Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study. Lancet Infect Dis. 2018;18(1):76–84. doi:10.1016/S1473-3099(17)30691-6 World Health Organization. Systematic Screening for Tuberculosis Disease. WHO Consolidated Guidelines for Tuberculosis. 2021; p5–35. Badan Penelitian dan Pengembangan Kesehatan. Laporan Nasional RISKESDAS 2018: Tuberkulosis. 2018; p80. Hartiyah L, Rahmiayti, Santoyo D. Gambaran hasil pemeriksaan tes cepat molekuler Mycobacterium tuberculosis di RSUD Ulin Banjarmasin tahun 2020–2021. 2023;6:69–76. Chinwong D, Mookmanee N, Chongpornchai J, Chinwong S. A comparison of gender differences in smoking behaviors, intention to quit, and nicotine dependence among Thai university students. J Addict. 2018;2018:1–8. doi:10.1155/2018/8081670 Kementerian Kesehatan Republik Indonesia. Rencana Aksi Nasional Kelompok Lanjut Usia. 2016; p22. World Health Organization. Global Tuberculosis Report 2022. 2022; p5–33. Peraturan Presiden Republik Indonesia. Penanggulangan Tuberkulosis. 2021; p2–26. Myneedu VP, Behera D, Verma AK, Bhalla M, Singh N, Arora J, et al. Xpert MTB/RIF assay for tuberculosis diagnosis: Evaluation in an Indian setting. Int J Tuberc Lung Dis. 2014;18(8):958–60. doi:10.5588/ijtld.13.0328 Zhang M, Xue M, He JQ. Diagnostic accuracy of the new Xpert MTB/RIF Ultra for tuberculosis disease: A preliminary systematic review and meta-analysis. Int J Infect Dis. 2020;90:35–45. doi:10.1016/j.ijid.2019.09.016 Bisognin F, Lombardi G, Lombardo D, Carla Re M, Dal Monte P. Improvement of Mycobacterium tuberculosis detection by Xpert MTB/RIF Ultra: A head-to-head comparison on Xpert-negative samples. PLoS One. 2018;13(8):1–7. doi:10.1371/journal.pone.0201934 Biswas S, Uddin MKM, Paul KK, Ather MF, Ahmed S, Nasrin R, et al. Xpert MTB/RIF Ultra assay for detection of Mycobacterium tuberculosis in people with negative conventional Xpert MTB/RIF but chest imaging suggestive of tuberculosis in Dhaka, Bangladesh. Int J Infect Dis. 2022;114:51–244. doi:10.1016/j.ijid.2021.11.010 Theron G, Venter R, Calligaro G, Smith L, Limberis J, Meldau R, et al. Xpert MTB/RIF results in patients with previous tuberculosis: Can we distinguish true from false positive results? Clin Infect Dis. 2016;62(8):995–1001. doi:10.1093/cid/civ1223 Horne DJ, Kohli M, Zifodya JS, Schiller I, Dendukuri N, Tollefson D, et al. Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults. Cochrane Database Syst Rev. 2019;6:7–11. doi:10.1002/14651858.cd009593.pub4 Kementerian Kesehatan Republik Indonesia. Petunjuk Teknis Penatalaksanaan Tuberkulosis Resisten Obat di Indonesia. 2020; p26–69.

The relationship between the level of physical activity and lung function Daswara Djajasasmita; Anastasia Y Triningtyas; Syafarina Afrila
ACTA Medical Health Sciences Vol. 3 No. 1 (2024): Acta Medical and Health Sciences
Publisher : ACTA Medical Health Sciences

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Physical activity is part of the basic needs of daily life, especially to improve the quality of health. Engaging in physical activity can increase blood flow through the lungs, causing oxygen to diffuse into the pulmonary capillaries with a larger or maximum volume. The purpose of the study was to determine the relationship between the level of physical activity and lung function. This study is a cross-sectional analytic study with a sampling technique of consecutive sampling, using a sample of 60 students of the Faculty of Medicine, Universitas Jenderal Achmad Yani who meet the inclusion and exclusion criteria. Research data were obtained using the International Physical Activity Questionnaire (IPAQ)-lf questionnaire instrument to assess physical activity levels and a vitalograph spirometer to assess FVC, FEV1 and FEV1/FVC. Data were analyzed using the Spearmann Rho Correlation Test. The results showed that there was a significant relationship between physical activity level and FVC% (p=0.008 and r=0.399) and FEV1% (p=0.000 and r=0.501), while there was no significant relationship between physical activity level and FEV1/FVC ratio (p=0.071 and r=0.235). Although there was no significant relationship between physical activity level and FEV1/FVC ratio, there was a positive and unidirectional relationship between physical activity level and all lung function parameters in this study. Physical activity is one factor that has a positive influence on the respiratory system.When done regularly there will be adaptation to the body by increasing ventilation for maximum oxygen uptake and better diffusion capacity, resulting in respiratory efficiency. Therefore, students are expected to do physical activity according to recommendations to achieve health benefits, including increasing lung function parameters such as FVC, FEV1 and FEV1/ FVC ratio. DOI : 10.35990/amhs.v3n1.p40-50 REFERENCES Hasibuan R. Terapi sederhana menekan gejala penyakit degeratif. Jurnal Ilmu Keolahragaan. 2010;8:78. World Health Organization. Global Status Report on Physical Activity 2022. Geneva: CC BY-NC-SA 3.0 IGO; 2022. Direktorat P2PTM, Kemenkes RI. Ayo Bergerak, Lawan Obesitas! Jakarta; 2017. World Health Organization. Global Health Risks: Mortality and Burden of Disease Attributable to Selected Major Risks. WHO Press; 2009. Hutapea MDS, Angliadi E. Perbandingan FEV1 pada mahasiswa yang aktif dan tidak aktif berolahraga. DOI: https://doi.org/10.35790/ecl.v1i1.3299. Zarkasi KA, Ramdzan AR, Ramli NZ. Physical inactivity among medical and non-medical students: a cross sectional study. Universiti Malaysia Sabah; 2015. Available from: https://www.researchgate.net/publication/309476739. Badan Litbangkes, Kemenkes RI. Hasil Utama Riskesdas 2018; 2018. World Health Organization. Physical activity. 2022 [cited 2023 Aug 7]. 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The relationship between menstrual cycle and psychological stress on acne vulgaris incidence Ania K P Dewi; Rina Munirah B; Westinawati Rahman H
ACTA Medical Health Sciences Vol. 3 No. 1 (2024): Acta Medical and Health Sciences
Publisher : ACTA Medical Health Sciences

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Acne vulgaris (AV) is a chronic inflammation of the pilosebaceous unit and presents with a polymorphic clinical picture such as comedones, papules, pustules, nodules, and scars. AV is often experienced by both women and men, affecting 85% of young adults aged 12-25 years, with women more commonly affected than men. There are several triggers that contribute to the onset of AV, including the menstrual cycle and psychological stress. This study aims to determine the relationship between the menstrual cycle, psychological stress, and the occurrence of acne vulgaris in female medical students at Universitas Jenderal Achmad Yani. The research design uses a cross-sectional study approach. There were 48 people who met the inclusion criteria. Respondents in this study were asked to fill out informed consent forms, questionnaires, and indicate their availability for standardized facial photos. The results of this study obtained a p-value of 1.000 and 0.529 (p-value > 0.05). It was found that there is no statistically significant association observed between either regular menstrual cycles or severe psychological stress and the presence of acne vulgaris in this sample. The odds ratios for both variables (1.052 and 1.303) suggest minor increases in the odds of acne vulgaris presence, but they do not reach statistical significance. This relates to the occurrence of acne vulgaris, which is not only caused by factors such as the menstrual cycle and psychological stress but also by various triggering factors including diet, use of cosmetics, facial hygiene, and unhealthy sleep patterns. DOI : 10.35990/amhs.v3n1.p51-59 REFERENCES Li D, Chen Q, Liu Y, Tang W, Li S. The Prevalence of Acne in Mainland China: a systematic review and meta-analysis. BMJ Open. 2017;7(8). Agesti D, Astuti S, Mustika A. Penanganan Jerawat Sindrom Akumulasi Dahak Menggunakan Akupunktur dan Herbal Jianghuang. J Vocational Health Studies. 2020;4:15–20. Jusuf NK, Putra IB, Sutrisno AR. Correlation Between Stress Scale and Serum Substance P Level in Acne Vulgaris. Int J Gen Med. 2021;14:681–686. Heng AH, Chew F. Systematic Review of the Epidemiology of Acne Vulgaris. Scientific Reports. 2020;10:5754. Sutaria AH, Masood S, Saleh HM, Schlessinger J. Acne Vulgaris. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Aug 6. Available from: https://www.ncbi.nlm.nih.gov/books/NBK459173/ Fadilah AA. Stres Psikologis Terhadap Timbulnya Akne Vulgaris. J Ilmu Kesehatan Sandi Husada. 2021;10:390–391. Wijayanti N, Diana ED, Irawanto ME. Hubungan Tingkat Stres dengan Derajat Keparahan Akne. Health Med J. 2023;5:39–43. Sirajudin A, Sibero HT, Anggraini DI. Prevalensi dan Gambaran Epidemiologi Akne Vulgaris di Provinsi Lampung. JK Unila. 2019;3:308–312. Lestari RT, Gifanda LZ, Kurniasari EL, Harwiningrum RP, Kelana AP, Fauziyah K, et al. Perilaku Mahasiswa Terkait Cara Mengatasi Jerawat. J Farm Komunitas. 2021;8:15–19. Hartono LM, Kapantow MG, Kairupan TS. Pengaruh Menstruasi terhadap Akne Vulgaris. E-CliniC. 2021;9:305–310. Prayuni ED, Imandiri A, Adianti M. Terapi Menstruasi Tidak Teratur dengan Akupunktur dan Herbal Pegagan (Centella asiatica L.). J Vocational Health Studies. 2018;2:86–91. Yadnya KS, Wiraguna AA, Karna NP, Sudarsa PS. Hubungan Stres Terhadap Timbulnya Akne Vulgaris pada Mahasiswa Fakultas Kedokteran Universitas Udayana Program Studi Pendidikan Dokter Angkatan 2017. J Medika Udayana. 2020;9:66–67. Basri M, Usman J, Islamiah N. Hubungan Stres dengan Kejadian Acne Vulgaris pada Mahasiswa Fakultas Kedokteran Universitas Muhammadiyah Makassar. J Komunitas Kesehatan Masyarakat. 2021;3:75–82. Musabiq SA, Karimah I. Gambaran Stres dan Dampaknya Pada Mahasiswa. InSight. 2018;20:74–79. Najmi FA, Ichlas I, Noneng E. Gambaran Tingkat Stres pada Mahasiswa Tahun Pertama Fakultas Kedokteran Universitas Jenderal Achmad Yani Angkatan 2016. Available from: https://doi.org/10.5281/zenodo Al-Falah AA, Subagio, Gading PW. Hubungan Pengetahuan dengan Tingkat Keparahan Jerawat (Acne Vulgaris) pada Mahasiswa Program Studi Kedokteran Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi. JOMS. 2021;2:11. Aziz T, Suryanti, Ramanda W. Faktor-Faktor yang Berhubungan dengan Timbulnya Acne Vulgaris pada Mahasiswi Angkatan 2021 Fakultas Kedokteran Universitas Batam. Zona Kedokteran. 2022;12:60. Roxanne J, Indira IG, Adiguna MS, Karmila IG. Proporsi dan Karakteristik Akne Vulgaris pada Mahasiswa Program Studi Sarjana Kedokteran dan Profesi Dokter Fakultas Kedokteran Universitas Udayana Tahun 2019. J Medika Udayana. 2021;10:91–97. Dewi AKP, et al. (Incomplete data, please review for clarification) Teresa A. Akne Vulgaris Dewasa: Etiologi, Patogenesis, dan Tatalaksana Terkini. J Kedokteran. 2020;8:953–960. Sihombing KA, Chalil MJ, Akbar A, Suryani D. 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Ibnu Sina: J Kedokteran dan Kesehatan FK UISU. 2022;21:20–24.

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Siska Telly Pratiwi

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amhs@fk.unjani.ac.id

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+6281322585754

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amhs@fk.unjani.ac.id

Editorial Address
Faculty of Medicine University Jenderal Ahmad Yani Jl. Terusan Jend.Sudirman PO BOX 148 Cimahi.

Location
Kota cimahi,

Jawa barat

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Siska Telly Pratiwi

Contact Email amhs@fk.unjani.ac.id

Phone +6281322585754

Journal Mail Official amhs@fk.unjani.ac.id

Editorial Address Faculty of Medicine University Jenderal Ahmad Yani Jl. Terusan Jend.Sudirman PO BOX 148 Cimahi.

Location Kota cimahi, Jawa barat INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Siska Telly Pratiwi

Contact Email
amhs@fk.unjani.ac.id

Phone
+6281322585754

Journal Mail Official
amhs@fk.unjani.ac.id

Editorial Address
Faculty of Medicine University Jenderal Ahmad Yani Jl. Terusan Jend.Sudirman PO BOX 148 Cimahi.

Location
Kota cimahi,

Jawa barat

INDONESIA