cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Nasri
Contact Email
nusantarascientific.journal@gmail.com
Phone
+6285943109283
Journal Mail Official
nusantarascientific.journal@gmail.com
Editorial Address
Jalan Jamin Ginting No. 55 Mangga, Kec. Medan Tuntungan, Kota Medan, Sumatera Utara 20142
Location
Kota medan,
Sumatera utara
INDONESIA
Nusantara Scientific Medical Research Journal
Published by Nusantara Scientific Medical
ISSN : -     EISSN : 29853508     DOI : https://doi.org/10.58549/nsmrj.v2i01.35
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Veterinary
Nusantara Scientific Medical Research Journal (E-ISSN: 2985-3508) is a journal that publishes Focus & Scope research articles, which include: Dentistry Nursery Midwifery Pharmacy Medical Science Biology Chemistry Nutraseutical Functional Food This journal is published by the Nusantara Scientific Medical, which is published April, August and December.
Arjuna Subject : Kedokteran - Farmakologi (Medis)
Articles 27 Documents
 1   2   3 
Screening of Drug Interaction Prescreption for Outpatients with Diabetes Mellitus and Hypertension from October to December 2023 at Advent Hospital Medan Khairatunawa, Tisa; Bangar, Roy Indrianto
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 3 No. 01 (2025): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/nsmrj.v3i01.101

Abstract

Diabetes mellitus and hypertension are two chronic conditions that frequently occur simultaneously and require long-term pharmacological therapy. The combination of treatments in patients with both diseases increases the potential for drug interactions, which can compromise therapeutic effectiveness and elevate the risk of adverse effects. This study aimed to evaluate the severity of drug interactions in outpatients with diabetes mellitus and hypertension at Advent Hospital Medan during the period from October to December 2023. A non-experimental descriptive study with a cross-sectional design was employed, using retrospective data from 191 outpatient prescriptions that met the inclusion criteria. Evaluation was conducted on administrative, pharmaceutical, and clinical aspects of the prescriptions, with a primary focus on identifying drug interactions using the reference database Drugs.com. The results showed that drug interactions were present in 52.4% of the analyzed prescriptions. Most interactions were classified as moderate in severity, predominantly involving pharmacodynamic mechanisms. The most frequent interacting drug combinations included metformin, glimepiride, amlodipine, bisoprolol, and candesartan. The high prevalence of drug interactions among patients with diabetes mellitus and hypertension highlights the importance of systematic prescription screening as a preventive measure. These findings can serve as a basis for developing rational drug use policies and enhancing patient safety in clinical practice.
Relationship Between the Level of Knowledge and Medication Adherence Level in Diabetes Mellitus Patients in Advent Medan Hospital Amazihono, Keytrin; Erida Novriani; Lubis, Asyrun Alkhairi
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 3 No. 01 (2025): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/nsmrj.v3i01.102

Abstract

Hyperglycemia or elevated blood sugar levels due to decreased pancreatic insulin productin, is a sign of a metabolic disorder that leads to diabetes mellitus (DM). One crucial factor in managing diabetes mellitus is the patient’s knowledge and adherence to treatment. Patients with adequate knowledge are more likely to comply with therapy, which helps control the disease. This study aims to determine the relationship between the level of knowledge and the level of medication adherence in diabetes mellitus patients in Advent Hospital Medan. This research employed a quantitative approach with a cross-sectional design and a purposive sampling technique. The research involved 90 patients who were selected and agreed to participate as respondents. Data were collected using a validated Diabetes Knowledge Questionnaire (DKQ-24) and Medication Adherence Report Scale (MARS-5). Data analysis was conducted using a non-parametric statistical test, specifically the Chi-Square test. The study found that the majority of patients had a high level of knowledge (48,9%) but were non-adherent to medication (56,7%). The Chi-Square test showed a significance of 0.001 < 0.05, indicating a significant relationship between the level of knowledge and medication adherence among diabetes mellitus patients at Advent Medan Hospital.
Isolation of Secondary Metabolites of Zingiberaceae Rhizomes by Spectrofotometry and Chromatography: A Review Supartiningsih, Supartiningsih; Mairani, Fridelly; Putri, Ananda Dwi; Panggabean, Indah Elsayanti; Situmorang, Imelda Stefani Overia; Erni, Erni; Marbun, Eva Diansari
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 3 No. 02 (2025): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/nsmrj.v3i02.133

Abstract

The Zingiberaceae family, known as the ginger family, is rich in secondary metabolites that contribute to its extensive use in traditional and modern medicine. Understanding effective methods for isolating these metabolites is crucial for advancing their pharmaceutical and nutraceutical applications. A literature review of 10 journal articles published between 2015 and 2025 was conducted. The focus was on spectrophotometric (UV-Vis, FTIR) and chromatographic (TLC, HPLC, LC-MS) techniques applied to the rhizomes of Zingiberaceae species. Data on compound identification, quantification, and method performance were analysed. Rhizomes of Curcuma aeruginosa, Alpinia purpurata, Zingiber officinale, and Boesenbergia pandurata were reported to contain flavonoids, alkaloids, phenolics, terpenoids, and curcuminoids. Spectrophotometric methods provided functional group identification and estimation of total metabolite concentrations. Chromatographic approaches enabled separation, purification, and structural elucidation with high specificity. Notably, flavenochromane C from Zingiber cassumunar and piperine from Alpinia purpurata were identified using LC-MS and NMR spectroscopy. In addition, TLC-densitometry for curcuminoids and xanthorrhizol in Curcuma xanthorrhiza demonstrated high accuracy and precision. Spectrophotometric techniques offer rapid and cost-effective screening, while chromatographic methods provide detailed identification and quantification of specific compounds. The complementary use of both approaches enhances the accuracy and reliability of isolating Zingiberaceae metabolites, supporting their further utilisation in medicinal research and product development.
The Effectiveness of Booklet Media on Knowledge About Anemia Among Adolescent Girls at Junior High School in Bandar Lampung Hardjasasmita, Aisyah Amalia Putri; Suja, Monica Dara Delia; Mugiati, Mugiati; Septiani, Ranny
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 3 No. 02 (2025): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/nsmrj.v3i02.110

Abstract

Anemia is a common health problem among adolescent girls, often caused by a lack of knowledge regarding its causes, symptoms, and prevention methods. Therefore, appropriate educational efforts are needed to improve awareness and understanding of anemia among teenagers. Booklets are considered an effective and accessible educational medium, particularly for adolescent groups. This study aimed to determine the effectiveness of booklet media in increasing knowledge about anemia among female students at SMP Negeri 14 Bandar Lampung. This study used a quantitative approach with a one-group pretest–posttest design. A total of 230 students were selected using Slovin’s formula. Data were collected using a 25-item questionnaire administered before and after the booklet intervention. Because the data were not normally distributed, analysis was conducted using the Wilcoxon Signed Rank Test. The mean pretest score was 42.52 and increased significantly to 98.99 in the posttest. The Wilcoxon test showed a significance value of p < 0.05 (p = 0.000), indicating a statistically significant difference in knowledge before and after the booklet intervention. In conclusion, booklet media is proven to be effective in improving adolescent girls’ knowledge about anemia. It serves as an easily understood educational tool and can be utilized to support school-based health education programs.
The Dangerous Of Using Food Preservatives To Human Health: A Review Tampubolon, Manuppak Irianto; Silitonga, Desni Rinanda; Ginting, Grace Anastasia br.; Berkat, Syukur; Sahputri, Cut Juliana; Ghifran, Muhammad Al; Marbun, Eva Diansari
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 3 No. 02 (2025): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/nsmrj.v3i02.127

Abstract

The use of formalin as a food additive remains a recurring issue in processed food products in Indonesia, particularly in perishable items such as wet noodles and tofu. This review examines ten published studies that investigated formalin detection across different regions of Indonesia using a range of analytical approaches, including the Nash reagent, UV-Vis spectrophotometry, rapid test kits, KMnO₄, Tollens reagent, and natural indicators. The findings reveal considerable regional variation in contamination levels, with positive results most frequently reported in Palembang, Yogyakarta, Tomohon, and Pringsewu, while samples from West Jakarta and Sorong were predominantly negative. Among the methods reviewed, the Nash reagent and UV-Vis spectrophotometry demonstrated higher accuracy and sensitivity, whereas simpler techniques were more appropriate for preliminary screening and public education. Overall, this review highlights the need for strong coordination between regulatory oversight, public awareness initiatives, and the availability of reliable detection methods to improve food safety in Indonesia.
Standardization of Rhizome Simplicia from the Zingiberaceae Family in Terms of Methods and Quality: A Review Silalahi, Yosy Cinthya Eriwaty; Surbakti, Christica Ilsana; Suharyanisa, Suharyanisa; Suryani, Monica; Ulfata, Zikri; Panjaitan, Grace Emmas Sondang; Marbun, Eva Diansari
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 3 No. 02 (2025): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/nsmrj.v3i02.128

Abstract

Simplicia rhizomes from the Zingiberaceae family are important raw materials in the traditional medicine industry, as they contain bioactive compounds such as flavonoids, alkaloids, and tannins. The quality of simplicia is strongly influenced by post-harvest processing methods, particularly drying. This study aims to systematically review the quality of Zingiberaceae rhizome simplicia based on ten national scientific journals published between 2015 and 2024. The method employed was a literature study using a qualitative descriptive approach, evaluating specific quality parameters (organoleptic characteristics, solubility, and phytochemical tests) and non-specific parameters (moisture content, ash content, and microbial contamination) according to the Indonesian Herbal Pharmacopoeia. The results indicate that oven drying at 50–60 °C for 24–48 hours produces the best-quality simplicia, characterized by moisture content below 10%, ash content within acceptable limits, and high flavonoid levels. Other drying methods, such as sun drying and natural air drying, showed more variable outcomes and in some cases exceeded standard limits, particularly in acid-insoluble ash levels and microbial contamination. Several simplicia samples obtained from traditional markets did not meet quality standards due to suboptimal washing and storage processes. This study concludes that simplicia quality standardization must comprehensively address technical stages from washing to drying. The use of extracts is more strongly recommended than raw simplicia to ensure consistency, stability, and safety of herbal products. Strict quality standards are essential to support the effectiveness of traditional medicines derived from Zingiberaceae.
Isolation and Analytical Characterization of Flavonoids from Indonesian Medicinal Plants: A Comprehensive Literature Review Chandra, Devina; Tampubolon, Manuppak Irianto; Safitri, Alfi; Sihombing, Johas; Sinaga, Dianty Secilia; Marbun, Eva Diansari
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 3 No. 02 (2025): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/nsmrj.v3i02.132

Abstract

Indonesia is recognized as one of the world’s megabiodiversity countries, possessing a vast range of medicinal plants that serve as rich sources of secondary metabolites, particularly flavonoids. These compounds are widely reported to exhibit significant pharmacological activities, including antioxidant, antidiabetic, and antibacterial effects, thereby encouraging continuous research on their isolation and identification. This study aims to systematically review the isolation and identification methods of flavonoid compounds derived from Indonesian medicinal plants, as well as to determine the most frequently reported flavonoid types and their pharmacological relevance. A literature review approach was applied by searching three scientific databases: Google Scholar, ScienceDirect, and ProQuest. Keywords used included “isolation and flavonoids” (Indonesian) and “isolation and flavonoid compounds” (English). Articles were selected based on inclusion criteria comprising publication period (2019–2024), journal accreditation, and full-text accessibility. From an initial pool of 13,400 records, only 10 articles met all eligibility criteria. The reviewed studies reported various isolation techniques, including maceration using ethanol or methanol, fractionation with ethyl acetate or water, and compound identification through Thin Layer Chromatography (TLC), UV–Vis spectrophotometry, and Nuclear Magnetic Resonance (NMR). The major flavonoids identified were quercetin, flavanone, and flavonol-3-O-galactose. Overall, Indonesian medicinal plants demonstrate strong potential as natural sources of flavonoids, with isolation and identification methods proving effective in detecting compounds with significant biological activity, particularly antioxidants.

Page 3 of 3 | Total Record : 27

 1   2   3 

Filter by Year

2022 2025


Reset
Filter By Issues
All Issue Vol. 3 No. 02 (2025): NSMRJ: Nusantara Scientific Medical Research Journal Vol. 3 No. 01 (2025): NSMRJ: Nusantara Scientific Medical Research Journal Vol. 2 No. 02 (2023): NSMRJ: Nusantara Scientific Medical Research Journal Vol. 2 No. 01 (2023): NSMRJ: Nusantara Scientific Medical Research Journal Vol. 1 No. 1 (2022): NSMRJ: Nusantara Scientific Medical Research Journal