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Ahmad Yani
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Journal of Public Health and Pharmacy
Published by Universitas Muhammadiyah Palu
ISSN : -     EISSN : 27754952     DOI : 10.56338/jphp
Core Subject : Health,
Medicine & Pharmacology Public Health
Journal of Public Health and Pharmacy is an national, peer-reviewed journal. It publishes original papers, reviews and short reports on all aspects of the science, philosophy, and practice of public health. It is aimed at all public health practitioners and researchers and those who manage and deliver public health services and systems. It will also be of interest to anyone involved in provision of public health programmes, the care of populations or communities and those who contribute to public health systems in any way. These include: Epidemiology Health education and behavioral science Environmental Health Occupational Health and Safety Biostatistics Health Administration and Policy Reproduction health Pharmacy This is not an exhaustive list and the Editors will consider articles on any issue relating to public health.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 187 Documents
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Anti-Adhesion Effect of Intraperitoneal Quercetin Associated with Caspase-3 Concentration in a Rat Model of Postoperative Peritoneal Adhesion Zikrul Haikal; Asra Al Fauzi; Maftuchah Rochmanti; Idyatul Hasanah
Journal of Public Health and Pharmacy Vol. 6 No. 3 (2026)
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v6i3.10492

Abstract

Introduction: Postoperative peritoneal adhesion is a common complication that can lead to severe morbidity, including chronic pain and intestinal obstruction. Adhesion formation involves an imbalance between proliferation and apoptosis of mesothelial cells, with suppression of caspase-3 activity playing a key role. Quercetin has been suggested to possess anti-adhesion potential through caspase-3 activation; however, experimental evidence supporting this mechanism remains limited. This study aims to evaluate the effect of intraperitoneal quercetin administration on caspase-3 levels and peritoneal adhesion formation in a Wistar rat (Rattus norvegicus) model following laparotomy. Methods: This true experimental study employed a posttest-only control design involving 36 healthy male Wistar rats aged 3–4 months and weighing 200–250 g. The animals were randomly allocated into two groups: control (normal saline irrigation) and treatment (intraperitoneal quercetin at 50 mg/kg body weight). Peritoneal adhesion was induced by standardized peritoneal abrasion. On post-operative day 7, evaluations included caspase-3 level measurement using ELISA and macroscopic adhesion grading with a validated scoring system. Statistical analysis was performed using the Mann–Whitney test. Results: Caspase-3 concentration in the quercetin-treated group was significantly higher than in the control group (2.968 ± 0.970 vs. 1.277 ± 0.482; p = 0.000), indicating enhanced apoptosis. The mean adhesion score was significantly lower in the quercetin group (1.280 ± 1.127 vs. 2.220 ± 1.047; p = 0.012), demonstrating a protective effect of quercetin against pathological adhesion formation. Conclusion: Intraperitoneal quercetin significantly reduces peritoneal adhesion formation and is associated with increased caspase-3 levels, suggesting a potential apoptosis-related mechanism. These findings support further investigation into its clinical applicability, including optimization of dosing, safety evaluation, and integration into perioperative pharmacotherapy protocols. If validated in human studies, quercetin may contribute to reducing surgical complications and associated healthcare burdens.
Effects of Moringa oleifera Leaf Extract on Serum 8-OHdG Levels in Alloxan-Induced Diabetic Rats Yuhendri Putra; Arni Amir; Eti Yerizel; Hasmiwati
Journal of Public Health and Pharmacy Vol. 6 No. 3 (2026)
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v6i3.11226

Abstract

Introduction: Oxidative stress contributes to the pathogenesis and complications of diabetes mellitus through excessive production of reactive oxygen species, which can lead to oxidative DNA damage. Serum 8-Hydroxy-2′-Deoxyguanosine (8-OHdG) is widely used as a biomarker of oxidative DNA damage. Moringa oleifera leaves contain various antioxidant compounds that may help modulate oxidative stress under diabetic conditions. This study aimed to evaluate the effects of Moringa oleifera leaf extract on serum 8-OHdG levels in alloxan-induced diabetic rats. Methods: This exploratory, randomized, post-test-only experiment included 25 male Wistar rats allocated to five groups (n = 5/group): non-diabetic control, alloxan-exposed diabetic control, and alloxan-exposed groups receiving Moringa oleifera leaf extract at 250, 500, or 1000 mg/kg body weight orally once daily for 14 days. Alloxan monohydrate was administered intraperitoneally at 150 mg/kg body weight. A fasting glucose level ≥200 mg/dL at 72 hours defined eligibility for the diabetic groups. Serum 8-OHdG was measured by enzyme-linked immunosorbent assay (ELISA), and group means were compared using one-way ANOVA with p < 0.05 as the significance threshold. Results: Serum 8-OHdG did not differ significantly among groups (F(4,20) = 1.55; p = 0.227). The 500 mg/kg group had the numerically lowest mean (0.367 ± 0.036 ng/mL), but this observation did not establish a treatment effect or an optimal dose. The diabetic control mean (0.416 ± 0.073 ng/mL) was not higher than the non-diabetic control mean (0.468 ± 0.108 ng/mL). Conclusion: This exploratory study did not demonstrate a statistically significant effect of Moringa oleifera leaf extract on serum 8-OHdG under the tested conditions. The observed numerical variation should be interpreted cautiously and does not establish antioxidant efficacy or an optimal dose. Larger, adequately powered studies with standardized extract characterization, longitudinal glycemic assessment, and additional oxidative stress markers are warranted.
Respiratory Symptom Composite, Individual Characteristics, and Area PM10 Measurements among Makassar Flour Mill Workers Tiara Rahmadhani; Atjo Wahyu; Yahya Thamrin; Masyita Muis; Andi Arsunan
Journal of Public Health and Pharmacy Vol. 6 No. 3 (2026)
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v6i3.11536

Abstract

Introduction: This study described an unvalidated respiratory symptom composite, individual characteristics, and concurrent spirometric screening among flour mill workers in Makassar, with short-duration area PM10 measurements providing descriptive workplace context. Methods: The cross-sectional study was conducted in December 2025. Archived aggregate tables included data for 87 workers; complete participation and source-data completeness could not be verified. The primary outcome was a study-specific, unvalidated 12-item composite using a ≥50% affirmative-response threshold. Crude prevalence ratios (PRs) and odds ratios (ORs) with nominal 95% confidence intervals (CIs) were reconstructed from categorical counts. Ten 10-minute area PM10 measurements were summarized separately. The unverifiable adjusted model was removed. Results: The composite threshold was met by 49/87 workers (56.3%). Crude PRs were 1.61 (95% CI 1.08–2.40) for the respiratory history composite, 2.44 (1.65–3.62) for service >5 years, and 2.62 (1.60–4.31) for former or current smoking versus never smoking. PPE use had a PR of 1.47 (0.996–2.180), and the exercise composite had a PR of 1.04 (0.72–1.52). Abnormal spirometric screening co-occurred with a higher composite-positive proportion (PR 2.56; 1.39–4.73), without implying a predictive relationship. PM10 ranged from 5 to 902 µg/m³. Estimates were unadjusted and CIs did not account for possible work-area clustering. Conclusion: Recorded individual characteristics differed in their crude association with the unvalidated symptom composite. These findings do not establish respiratory disease prevalence, independent determinants, or causation. Area measurements cannot establish individual PM10–symptom associations or regulatory compliance. The findings identify priorities for better-documented exposure assessment and respiratory surveillance.  
Factors Associated with Quality of Life among Women Living with HIV in Bali Putu Dian Prima Kusuma Dewi; Putu Sukma Megaputri; Ni Made Karlina Sumiari Tangkas
Journal of Public Health and Pharmacy Vol. 6 No. 3 (2026)
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v6i3.9474

Abstract

Introduction: Women living with HIV (WLHIV) face greater social, economic, and psychological burdens than men, which directly affect their quality of life. This study aimed to examine factors associated with quality of life among women living with HIV receiving antiretroviral therapy (ART) in Bali, Indonesia. Methods: This quantitative cross-sectional study included 197 women receiving ART in Jembrana and Gianyar districts, Bali. Data were collected through structured interviews using the WHOQOL-HIV BREF questionnaire and analyzed using ordinal logistic regression (ologit) in Stata 17. Quality of life (QoL) was categorized as high, moderate, or low. Results: Most respondents (90.4%) had low quality of life. Factors significantly associated with quality of life included educational attainment (β = −0.958, AOR = 0.38, 95% CI: 0.20–0.74, p = 0.005), employment status (β = −1.37, AOR = 0.25, 95% CI: 0.06–0.94, p = 0.040), medication adherence support (β = 0.39, AOR = 1.48, 95% CI: 1.01–2.17, p = 0.040), and a history of forgetting antiretroviral medication (β = 4.61, AOR = 100.76, 95% CI: 6.31–1610.08, p = 0.001). Lower educational attainment and unemployment were associated with poorer quality of life, whereas treatment adherence and medication adherence support were associated with better well-being among women living with HIV. Conclusion: A holistic approach integrating medical, psychosocial, and family support may help improve quality of life among women living with HIV and support adaptation to chronic illness. Promotive and preventive interventions should focus on strengthening family and peer support, expanding health education, and addressing social stigma to help women living with HIV maintain optimal QoL.
Household Container Characteristics Associated with Mosquito Larval Presence in a Highland Community of Tana Toraja, Indonesia Nismawati Natsir; A. Arsunan Arsin; Hasanuddin Ishak; Ilham Alimuddin; Masni Masni; Muhammad Nasrun Massi; Anwar Mallongi
Journal of Public Health and Pharmacy Vol. 6 No. 3 (2026)
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v6i3.10863

Abstract

Introduction: Dengue continues to pose a major mosquito-borne public health problem in tropical countries, including Indonesia, where household water containers frequently serve as habitats for mosquito larvae. However, studies examining household container characteristics associated with mosquito larval presence in highland communities remain limited. Methods: A community-based cross-sectional study was conducted in Bombongan Urban Village, Makale District, Tana Toraja Regency, South Sulawesi, Indonesia. The study included 100 households and 128 water-holding containers. Container type, functional container category, container condition, and mosquito larval presence were recorded through direct field observation. Associations were examined using Pearson’s chi-square test and a binary logistic generalized estimating equations (GEE) model to account for household-level clustering. Results: Of the 128 inspected water-holding containers, 89 (69.5%) were positive for mosquito larvae, and 94 (73.4%) were open. At the household level, 71 of 100 households had at least one larva-positive container, resulting in a House Index of 71.0%, a Container Index of 69.5%, and a Breteau Index of 89. Discarded containers had the highest proportion of larval positivity (91.7%), whereas animal drinking containers were the most frequently observed type. Functional container category was associated with larval presence in the bivariate analysis (p = 0.025) and remained significant as an overall variable in the GEE model (Wald χ² = 12.178, df = 3, p = 0.007), although none of the individual categories differed significantly from animal drinking containers. Open containers had substantially higher adjusted odds of larval presence than closed containers (aOR = 73.56; 95% CI: 21.74–248.87; p < 0.001). Conclusion: Open container condition was independently associated with mosquito larval presence, whereas functional container category showed a significant overall association. Discarded containers had the highest larval positivity, whereas animal drinking containers were the most frequently observed. Household mosquito-control measures may prioritize covering, emptying, cleaning, and appropriately disposing of water-holding containers.
Factors Associated with Patient Contact Management and Self-Reported Infection Risk Exposure Status Among Healthcare Workers: A Retrospective Cross-Sectional Study in Palu City, Indonesia Ismawati; Chatarina Umbul Wahyuni; Arief Hargono; Andi Arsunan Arsin; Daniel Akbar Wibowo; Esther Lenny Dorlan Marisi
Journal of Public Health and Pharmacy Vol. 6 No. 3 (2026)
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v6i3.11223

Abstract

Introduction: Effective disaster management at national and global levels remains a major challenge in preparing for future pandemic risks. Experiences from major outbreaks such as Ebola, SARS, and COVID-19 highlight the need to strengthen emergency response systems in healthcare facilities. Patient contact management is an important component of infection-risk mitigation in healthcare settings because it aims to interrupt the transmission of infectious microorganisms. This study aimed to analyze factors associated with patient contact management and self-reported infection-exposure risk status among healthcare workers during the COVID-19 pandemic in Palu City, Indonesia. Methods: This quantitative retrospective cross-sectional study was conducted from April 2024 to July 2025 at 14 community health centers and one regional hospital in Palu City, Indonesia. Using proportional stratified random sampling, 131 participants were selected from a population of 198 healthcare workers. Data were analyzed using the chi-square test and Cramer's V. Results: Health-worker protection measures (p < 0.001; Cramer's V = 0.543) and infection zoning (p < 0.001; Cramer's V = 0.612) showed the strongest associations with patient contact management, followed by institutional/facility policy (p < 0.001; Cramer's V = 0.506) and triage management (p < 0.001; Cramer's V = 0.500). Workplace, gender, and contact duration were not significantly associated with patient contact management (p > 0.05). Self-reported interactions lasting 3–5 minutes were the most frequent during patient care; however, contact duration was not significantly associated with either patient contact management or infection-exposure risk. Clinical skills were significantly associated with self-reported infection-exposure risk (p < 0.001; Cramer's V = 0.361). Conclusion: Patient contact management among healthcare workers was associated with individual and institutional factors, including knowledge, institutional/facility policy, health-worker protection, triage management, and infection zoning. Self-reported infection-exposure risk was significantly associated with healthcare workers' clinical skills.
Perceived Usability of a Ferritin Rapid Diagnostic Test Among Primary Healthcare Professionals: A Simulation-Based Evaluation Ima Arum Lestarini; Oktia Woro Kasmini Handayani; Mahalul Azam; Eko Farida
Journal of Public Health and Pharmacy Vol. 7 No. 1 (2027)
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v7i1.11347

Abstract

Introduction: Early identification of iron deficiency remains challenging in many primary healthcare settings because conventional ferritin testing requires laboratory infrastructure that may be limited in resource-constrained settings. A Ferritin Rapid Diagnostic Test (Ferritin RDT) has been developed as a point-of-care approach to facilitate ferritin assessment. Evaluating its perceived usability among intended healthcare users is an important preliminary step before field-based evaluation. To evaluate the perceived usability of a newly developed Ferritin Rapid Diagnostic Test among primary healthcare professionals following standardized training and supervised simulation. Methods: A descriptive quantitative evaluative study was conducted among 20 healthcare professionals from primary healthcare facilities in Mataram City and West Lombok Regency, Indonesia. Participants received standardized training and independently performed a supervised simulation using the Ferritin RDT, a lateral flow immunoassay for qualitative ferritin assessment. The test used serum specimens and provided visual results based on purple-colored control and test lines. After the simulation, participants completed the 10-item System Usability Scale (SUS). One participant did not complete the SUS questionnaire and was excluded from the usability analysis; therefore, 19 complete SUS responses were analyzed. Descriptive statistics were used to summarize participant characteristics and SUS scores, and brief open-ended comments were reported as preliminary user feedback. Results: Among the 19 participants with complete SUS responses, the mean SUS score was 78.68 (SD = 13.52), with a median of 77.50 (IQR = 71.25–88.75) and a range of 50–100. Sixteen participants (84.2%) had SUS scores ≥68, whereas three (15.8%) scored below this benchmark. The overall score corresponded to a good adjective rating, Grade B, and an Acceptable usability classification. Item-level responses generally indicated favorable perceptions of ease of use, learnability, functional integration, and confidence during use. Brief open-ended comments were generally positive, although one participant suggested reducing the testing time. Conclusion: The Ferritin RDT demonstrated favorable perceived usability among primary healthcare professionals following standardized training and supervised simulation. These findings provide preliminary evidence of usability under simulated conditions but do not establish diagnostic accuracy, technology acceptance, implementation readiness, or routine adoption. Further field-based studies are needed to evaluate the Ferritin RDT under real-world primary healthcare conditions.

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