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Antigen: Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Published by Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia
ISSN : 30266084     EISSN : 30266092     DOI : 10.57213
Core Subject : Health,
Health Professions Public Health
Jurnal ini adalah Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi yang bersifat peer-review dan terbuka. Bidang kajian dalam jurnal ini termasuk riset Kesehatan Masyarakat dan Ilmu Gizi.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 180 Documents
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Literature Review: The Potential of Tea as an Immunomodulator Through Its Antioxidant and Anti-Inflammatory Properties Sekar Puja Alya Maharani
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 3 No. 3 (2025): Agustus: Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v3i3.738

Abstract

<p style="text-align: justify;"><em>The immune system is an important mechanism to fight various pathogens. To fight pathogens, external substances are needed to improve performance and prevent pathological impacts of the immune system. Tea is one of the immunomodulatory substances that plays a role in increasing endurance because it has antioxidant and anti-inflammatory functions. This study aims to determine the potential of tea as an immunomodulator through antioxidant and anti-inflammatory mechanisms. The method used is a literature review using scientific articles that are adjusted to the inclusion criteria. Based on the results of the literature review, it shows that tea containing polyphenol compounds has an effect on reducing the levels of inflammatory cytokines such as TNF-&alpha; and IL-6 and increasing the activity of antioxidant enzymes (SOD, CAT) and reducing markers of oxidative stress.</em></p>
Literature Review: Dampak Warfarin terhadap Risiko Kanker Maleeka Jasmine Nadzira Ramadhani
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 3 No. 3 (2025): Agustus: Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v3i3.740

Abstract

Venous Thromboembolism (VTE) is a common complication in cancer patients. The treatment of VTE in cancer patients involves anticoagulant therapy using Vitamin K Antagonists (VKAs), including warfarin. VTE can be managed with warfarin administration, typically preceded by bridging therapy with heparin. The objective of this literature review is to examine and analyze studies related to the impact of warfarin use on cancer risk. The review was conducted on articles published in English over the past 10 years (2013–2024) using electronic databases such as Google Scholar and PubMed. The findings suggest that warfarin may be associated with improved overall survival in cancer patients and may have protective effects against certain types of cancer. Warfarin may exhibit antineoplastic properties through mechanisms both dependent on and independent of coagulation pathways, the latter mediated by the inhibition of the GAS6-AXL signaling pathway.  
Pengaruh Penggunaan Terapi Antosianin terhadap Penyakit Alzheimer :  Literature Review Chintya Dorinda Chandany
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 3 No. 3 (2025): Agustus: Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v3i3.741

Abstract

Alzheimer’s disease is the most common form of neurodegenerative disorder, characterized by cognitive decline, β-amyloid plaque accumulation, and oxidative stress in brain tissue. One promising alternative therapy is the use of anthocyanins, flavonoid compounds found in various red, purple, and blue-colored plants. This study aims to review the effectiveness of anthocyanins in preventing and slowing the progression of Alzheimer’s disease through a literature review. Articles published between 2014 and 2024 were selected from PubMed, Scopus, and Google Scholar databases, with inclusion criteria focusing on preclinical animal studies evaluating the effects of anthocyanins on neurodegenerative markers. The results show that anthocyanins, particularly pelargonidin and delphinidin, play a role in improving memory, reducing oxidative stress, and inhibiting β-amyloid plaque formation in animal models. Anthocyanins also enhance antioxidant enzyme activity and reduce neuronal apoptosis. These findings support the potential of anthocyanins as neuroprotective agents in Alzheimer’s therapy, although further clinical research is required to validate their efficacy in humans.
Pengaruh Kecanduan Merokok dan Vape pada Remaja: Literatur Review Telsa Amanda; Tursina Tursina; Marniati Marniati
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 3 No. 3 (2025): Agustus: Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v3i3.746

Abstract

The habit of smoking and using e-cigarettes (vape) among adolescents in Indonesia shows a significant increasing trend. This study aims to conduct a systematic review of various factors that influence dependence on cigarettes and vapes in adolescents, by analyzing 30 national scientific articles. The results of the review revealed that the dominant factors contributing to this behavior include the influence of the friendship environment, permissive parental attitudes, lack of knowledge, psychological pressure, and exposure to the media. In addition, education was found to be an effective strategy in increasing understanding and reducing smoking intentions. This behavior is also driven by the mistaken view that vaping is considered safer than regular cigarettes. This study suggests the need for a cross-sectoral approach, which includes ongoing education, regulatory enforcement, and the active role of families and educational institutions in efforts to prevent and control cigarette and vape addiction among adolescents.
Mencegah Kecelakaan Kerja dengan Strategi Efektif untuk Meningkatkan Keselamatan di Tempat Kerja: Literatur Review Putri Tasya Najla; Elda Zianyu Safani; Marniati Marniati
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 3 No. 3 (2025): Agustus: Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v3i3.749

Abstract

Abstract. Work accidents are a serious problem that can result in injury, disability, even death for employees, as well as financial losses for the company. In Indonesia, the number of work accidents still shows a questionable number, so that prevention of work accidents must be a top priority in occupational safety and health (K3) management. This study aims to explore and develop effective work accident prevention strategies. Methods: used in this study is a literature review, by collecting and analyzing information from various journals and scientific articles related to work accidents and their prevention strategies. The population in this study were various studies that discussed work accidents, while samples were taken from relevant articles. The research variables include risk factors for work accidents and prevention strategies applied. Results: nshowed that the implementation of safety training programs, building a strong safety culture, and implementing the 5R principle (Ringkas, Neat, Resik, Rawat, Rajin) can significantly reduce the risk of work accidents. Conclusion: from this study is that investment in a holistic and sustainable safety strategy is essential to creating a safe and productive work environment, as well as protecting employee health and safety. With these steps, companies are expected to be able to improve overall operational performance and efficiency. Keywords: work accidents, safety, strategies. Abstrak. Kecelakaan kerja merupakan masalah serius yang dapat mengakibatkan cedera, cacat, bahkan kematian bagi karyawan, serta kerugian finansial bagi perusahaan. Di Indonesia, angka kecelakaan kerja masih menunjukkan angka yang mengkhawatirkan, sehingga pencegahan kecelakaan kerja harus menjadi prioritas utama dalam manajemen keselamatan dan kesehatan kerja (K3). Penelitian ini bertujuan untuk mengeksplorasi dan mengembangkan strategi pencegahan kecelakaan kerja yang efektif. Metode yang digunakan dalam penelitian ini adalah tinjauan pustaka, dengan mengumpulkan dan menganalisis informasi dari berbagai jurnal dan artikel ilmiah terkait kecelakaan kerja dan strategi pencegahannya. Populasi dalam penelitian ini adalah berbagai studi yang membahas kecelakaan kerja, sedangkan sampel diambil dari artikel-artikel yang relevan. Variabel penelitian meliputi faktor risiko kecelakaan kerja dan strategi pencegahan yang diterapkan. Hasil menunjukkan bahwa penerapan program pelatihan keselamatan, pembangunan budaya keselamatan yang kuat, dan penerapan prinsip 5R (Ringkas, Rapi, Resik, Rawat, Rajin) dapat mengurangi risiko kecelakaan kerja secara signifikan. Kesimpulan dari penelitian ini adalah bahwa investasi dalam strategi keselamatan yang holistik dan berkelanjutan sangat penting untuk menciptakan lingkungan kerja yang aman dan produktif, serta melindungi kesehatan dan keselamatan karyawan. Dengan langkah-langkah ini, diharapkan perusahaan dapat meningkatkan kinerja dan efisiensi operasional secara keseluruhan. Kata kunci: kecelakaan lingkungan kerja, keselamatan, strategi.
Hubungan Asupan Lemak, Kalsium, Magnesium, dan Aktivitas Fisik dengan Derajat Dismenorea pada Mahasiswa Fakultas Ilmu Keolahragaan dan Kesehatan Universitas Negeri Surabaya Novanda Isnain Ramadhani; Amalia Ruhana
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 3 No. 3 (2025): Agustus: Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v3i3.753

Abstract

Dysmenorrhea is pain during menstruation experienced by women of childbearing age. Risk factors that can cause dysmenorrhea include age of menarche, family history, duration and menstrual cycle, stress, physical activity, nutritional status, and nutrient intake. Some nutrients that are related to the incidence of dysmenorrhea include fat, calcium, and magnesium. This study aims to determine the relationship between fat, calcium, magnesium, and physical activity intake with the severity of dysmenorrhea in students of the Faculty of Sport and Health Sciences, Surabaya State University. This study used a cross-sectional approach. The sampling technique used stratified random sampling with a total of 119 samples. Data collection used the NRS (Numeric Rating Scale) questionnaire for the incidence of dysmenorrhea, SQ-FFQ (Semi Quantitative Food Frequency) for fat, calcium, and magnesium intake, and IPAQ-SF (International Physical Activity Questionnaire-Short Form) for physical activity. The results showed that students of the Faculty of Sport and Health Sciences, Surabaya State University had low fat intake (79%), low calcium intake (58%), normal magnesium intake (47,9%), heavy physical activity (47,1%) and mild dysmenorrhea pain (40,3%). Data analysis using the Spearman Rank test showed a value of p = 0.000 (fat), p = 0.023 (calcium), p = 0.023 (magnesium), and p = 0.039 (physical activity). Based on the results of the study, it can be concluded that there is a significant relationship between fat, calcium, magnesium, and physical activity intake with the severity of dysmenorrhea (p <0.05).
Potensi Buah Jamblang (Syzygium cumini (L.) sebagai Agen Anti-Kanker yang Efektif pada Manusia Pramesti, Andita Wahyuning
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 3 No. 3 (2025): Agustus: Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v3i3.755

Abstract

Cancer is a malignant disease caused by the abnormal growth of cells in body tissues, making it one of the leading causes of death worldwide. The high prevalence of cancer has driven the search for new, effective, and safe anti-cancer agents, one of which involves utilizing phytochemical compounds from plants such as Java plum (Syzygium cumini), which has attracted attention as a potential anti-cancer agent due to its therapeutic potential and low toxicity. This literature review examines recent studies on the anti-cancer activity of Java plum across various cancer types through in vitro studies. The results show that Java plum exhibits several key mechanisms in inhibiting cancer cell growth, including induction of apoptosis, cell cycle arrest, inhibition of cell proliferation, ROS production, targeting of cancer stem cells, anti-inflammatory effects, modulation of epigenetic changes, and antioxidant protection.
Hubungan Status Gizi terhadap Premenstrual Syndrome pada Mahasiswi Kesehatan dan Non-Kesehatan Universitas Airlangga Sofia Zahrani
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 3 No. 3 (2025): Agustus: Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v3i3.756

Abstract

Premenstrual Syndrome (PMS) is a collection of physical and emotional symptoms occurring prior to menstruation that can disrupt daily activities. Dietary patterns and nutritional status are known to influence PMS symptoms. This study aims to analyze the relationship between dietary intake (energy, carbohydrates, protein, fat, magnesium, and vitamin B6) and nutritional status (based on Body Mass Index/BMI) with the incidence of PMS among female students from both health and non-health study programs at Universitas Airlangga. This research employed an analytical observational study with a cross-sectional design. A total of 103 female students from the 4th semester of the Nutrition and Islamic Economics study programs were selected through proportional random sampling. Data were collected using questionnaires on respondent characteristics, a Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ), anthropometric measurements, and the Shortened Premenstrual Assessment Form (SPAF). Data analysis was performed descriptively and inferentially using Spearman's rank correlation test. The results showed a significant relationship between energy intake (p = 0.002) and fat intake (p = 0.001) with PMS. No significant relationship was found for carbohydrate, protein, magnesium, and vitamin B6 intake (p > 0.05). Additionally, nutritional status based on BMI was significantly associated with PMS (p = 0.001), indicating that both underweight and overweight students were more likely to experience PMS. These findings highlight that imbalanced energy and fat intake, as well as abnormal nutritional status, may be contributing factors to PMS. Therefore, increasing awareness of proper nutrition and reproductive health is essential to reduce PMS symptoms among female students.
Efektivitas  Edukasi  Bahaya  Pergaulan  Bebas  dan  HIV/AIDS  pada  Siswa  MTSN  1  Konawe  Selatan Hartati Bahar; Shabilla Ananta Putri Baso; Gita Marzan Cahyani; Wa Ode Fazrah Fatimah; Putri Kalsum; Tatya Devina Pratiwi6; Tabita Sombo
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 3 No. 3 (2025): Agustus: Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v3i3.759

Abstract

Adolescents are classified as an age group vulnerable to various health and social issues, including engagement in promiscuous behavior, which is considered to carry a high risk of HIV/AIDS transmission. According to national data from 2022, Southeast Sulawesi was ranked 29th with a total of 1,516 reported cases of HIV/AIDS. In Kendari City, 272 new cases were recorded from January to November 2022. Meanwhile, in South Konawe Regency the site of this study 9 HIV cases were reported in 2023 and 5 cases in 2024. This study was conducted with the aim of improving students’ knowledge regarding the dangers of promiscuity and HIV/AIDS through the implementation of educational activities carried out at MTSN 1 South Konawe. The method employed in this study was a quantitative approach using a pre-experimental design, specifically a one-group pretest-posttest design. The population of this study consisted of 30 students from grades VII and VIII at MTSN 1 South Konawe in the year 2025. The sampling technique used was purposive sampling, with a total of 30 respondents selected. Data were collected using questionnaires administered to respondents before and after an educational session was delivered using the interactive educational game "True-False". The data were analyzed using a paired test. Based on the results of the study, it was found that the “True-False” educational game had a significant impact on improving students’ knowledge, attitudes, motivation, and actions regarding promiscuity and HIV/AIDS. This was indicated by the p-values for knowledge (0.000) < α (0.05), attitude (0.000) < α (0.05), student motivation (0.000) < α (0.05), and student action (0.000) < α (0.05).
Hubungan Pengetahuan Kesehatan Reproduksi dengan Perilaku Seksual Remaja Divya Salsabilla Vemala Putri; Andriyani Andriyani; Nurmala Lusida
Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi Vol. 3 No. 3 (2025): Agustus: Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/antigen.v3i3.761

Abstract

Adolescence is a transition from childhood to adulthood that experiences development of access to enter the adult phase including the function of reproduvtive organs. Deviant sexual behavior usually occurs among adolescents who have less knowledge of reproductive health and up finding out through peers or the internet whose truth is not yet know. Lack of information in this aspect encourges sexual behavior, which leads to unwanted pregnancies and sexually transmitted diseases, as well as mental disorders. The purpose of this study was to determine the relationship between reproductive health knowledge and adolescent sexual behavior. The method used is a quantitative or cross-sectional approach, involving several respondents who were selected purposively. The research instrument was  a standardized questionnaire that passed the validity and reability test. The results showed a relationship between the level of reproductive health knowledge and sexual behavior in adolescents, where adolescents who have broader insights show good or responsible sexual behavior. From the research result, it is concluded that there is a need for a comprehensive reproductive health education program for adolscents in schools, families, and social environments to build safe sexual behavior.  

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