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Vania Snatika Putri
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INDONESIA
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat
Published by Politeknik Indonusa Surakarta
ISSN : 25486667     EISSN : 27759032     DOI : 10.46808
Core Subject : Health, Science,
Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health
The journal includes various fields of pharmaceuticals sciences such as: Pharmacy, Pharmacokinetics, Community and Clinical Pharmacy, Medical, Alternative medicines, Synthetic Organic Chemistry, Organic Chemistry of Natural Material, Biochemistry, Chemical Analysis, Microbiology, Tissue Culture, Botany and Animals Related to Pharmaceutical Products, Midwifery, Health Analyst, Nutrition and Public Health, Pharmacology and Toxicology
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 162 Documents
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PERAN PENGETAHUAN DAN SIKAP REMAJA PEREMPUAN DALAM PRAKTIK PENCEGAHAN ANEMIA DI GONDANGREJO, KARANGANYAR Wahyu Ratri Sukmaningsih; Anggraini Luthfiyyah Syarry Handoko; Dyah Ayu Pitaloka
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 1 (2025): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i1.234

Abstract

One of the public health problems is anemia in adolescent girls, which has an impact on growth, development, and productivity. It is expected that good knowledge and attitudes can help carry out effective anemia prevention measures. This study aims to study how the knowledge and attitudes of adolescent girls in Gondangrejo District, Karanganyar, contribute to anemia prevention practices. This study employed a quantitative observational analytic method with a cross-sectional design involving 30 adolescent girls selected through purposive sampling. Data were collected using a structured questionnaire that had been tested for validity and reliability. Data analysis was conducted using univariate and bivariate methods with the Chi-square test. The majority of respondents demonstrated positive levels of knowledge and attitudes towards anemia prevention. There was a significant relationship between knowledge level (p = 0,002) and attitude (p = 0,001) with anemia prevention practices. Knowledge and attitude play an important role in promoting anemia prevention practices among adolescent girls. Continuous educational efforts need to be enhanced to optimize anemia prevention within this population. Keywords: Anemia, Knowledge, Practice, Adolescent Girls, Attitude
EVALUASI WAKTU TUNGGU PELAYANAN RESEP OBAT PASIEN RAWAT JALAN DI PUSKESMAS PEDAN KABUPATEN KLATEN Riyan Setiyanto; Vania Santika Putri; Agustina Sri Utami
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 1 (2025): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i1.237

Abstract

Pharmaceutical services at community health center are the final stage of the servive process which is a service for taking medicines with the provision that the waiting time for prescription services for compounded medicines ≤60 minutes and prescriptions for non-compounded medicines ≤30 minutes. Waiting time prescription services has an important role in health services, because service time is factor for measuring the effectiveness of an organization which consists of accuracy and speed of time. This study aims to determine the average waiting time for prescription drug services at Pedan Health Center, Klaten Regency. This type of research is non-experimental quantitative descriptive with a sampling method, namely incidental sampling carried out by chance using a form for waiting time for prescription drug services. The number of samples taken was 100 prescription sheets consisting of 50 compouned drug prescriptions and 50 non-compounded drug prescriptions. Evaluation of research data was carried out by comparing the result of the average waiting time at the community health center with the applicable laws and regulations. The results of research at the Pedan Community Health Center showed an average waiting time for services for compounded drug prescriptions of 19,92 minutes and non- compounded prescriptions of 11,88 minutes. This show that the average waiting time for prescriptions drug services at the Pedan Community Health Center has met the Minimum Service Standards (SPM) in the healt sector in Minister of Healt Regulation No 4 of 2019, namely compounded prescriptions services ≤60 minutes and non-compounded prescriptions ≤30 minutes. Factors that can influence the length of waiting time for prescription drug services are human resource factors (pharmacy pesonel), equipment used, material factors and method factors. Keywords: Medicine, Community health center, Services, Prescription, Waiting time
FORMULASI SEDIAAN MASKER GEL PEEL-OFF KOMBINASI EKSTRAK DAUN SIRIH (Piper betle L.) DAN MADU (Mel depuratum) SERTA UJI EFEKTIVITAS ANTIBAKTERI TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 DAN Propionibacterium acnes ATCC 6919 Indah Agustianingsih Permatasari Subakti; Tatiana Siska Wardani; Anna Fitriawati
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 1 (2025): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i1.238

Abstract

Skin prone to bacterial infections requires special care with antibacterial products. Betel leaf (Piper betle L.) and honey (Mel depuratum) are known for their antibacterial properties. This study aimed to evaluate the physical properties of peel-off gel masks and assess the antibacterial activity of the extracts against Staphylococcus aureus ATCC 25923 and Propionibacterium acnes ATCC 6919. The research used an experimental laboratory method with antibacterial testing through the disc diffusion method. One-Way ANOVA and Tukey HSD post-hoc tests were used to analyze the results.The peel-off gel mask preparations met the required physical standards, with acceptable spreadability, adhesiveness, drying time, and pH. The antibacterial test showed moderate activity, with average inhibition zones of 6.64 mm and 5.71 mm against Staphylococcus aureus, and 8.10 mm and 6.50 mm against Propionibacterium acnes for formulas 1 (20% betel leaf extract) and 3 (10% betel leaf extract and 10% honey). While honey didn’t show antibacterial effects in the mask, it helped maintain skin hydration. The ANOVA results showed a significant difference (p-value < 0.05) in antibacterial activity of the gel masks containing betel leaf extract and honey.
PATIENT SATISFACTION STUDY TOWARDS COMPLAINT HANDLING RESPONSIBILITY IN INPATIENT SERVICES AT HOSPITAL “X” Dewi Weni Sari; Kharisma Jayak Pratama; Annora Rizky Amalia
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 1 (2025): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i1.240

Abstract

Abstrak Kepuasan pasien merupakan point penting dalam menilai mutu layanan di rumah sakit. Responsivitas rumah sakit dalam menangani komplain pasien sangat mempengaruhi kepuasan. Tujuan dalam penelitian ini untuk mengetahui kepuasan pasien terhadap responsivitas penanganan komplain di layanan rawat inap rumah sakit ‘X”. Penelitian ini menggunakan metode deskriptif kuantitatif dengan menyebarkan kuisioner kepada 100 pasien rawat inap yang pernah menyampaikan komplain selama perawatan dan melakukan wawancara kepada kepala bagian penanganan komplain di rumah sakit. Analisis data menggunakan rumus CIS untuk melihat persentasi kepuasan pasien terhadap penanganan komplain yang diberikan oleh petugas di rumah sakit dan studi pustaka. Hasil penelitian menunjukan bahwa secara keseluruhan tingkat kepuasan pasien rawat inap terhadap responsivitas penanganan komplain di rumah sakit mendapatkan nilai sebesar 93,79%. Dari wawanacara yang dilakukan penanganan komplain di rumah sakit sudah terstruktur menggunakan SOP sebagai pedomannya, penyampaian komplain bisa secara langsung atau lisan (disampaikan ke perawat secara langsung atau via telpon) dan tidak langsung (kotak saran, email dan media sosial rumah sakit).
EVALUASI PENGADAAN OBAT DENGAN E-PURCHASING MELALUI E-CATALOGUE DI RUMAH SAKIT UMUM DADI KELUARGA PURWOKERTO Siti Asadu Sofiah; Sugianto Sugianto
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 1 (2025): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i1.243

Abstract

A drug procurement arrangement is made based on the e-purchasing method through e-catalogues to improve the efficiency, effectiveness, and transparency of the drug procurement process for the JKN program. Dadi Keluarga Hospital Purwokerto first used e-catalogues as its procurement method in 2021, which previously used the direct procurement method. In 2023, Dadi Keluarga Hospital Purwokerto did not use the drug procurement method with e-catalogues and returned to using it in 2024, so it is necessary to evaluate drug procurement with e-catalogues at Dadi Keluarga Hospital Purwokerto. This research is a non-experimental qualitative study with a case study that describes the obstacles encountered when procuring drugs through e-catalogues. The results showed several obstacles when implementing drug procurement through e-catalogues, such as the system in the e-catalogue not being optimal, drugs being out of stock by the provider, and the delivery time of goods tending to be long. In addition to these obstacles, procurement with e-catalogues is included in the efficient and effective drug procurement method.
RASIONALITAS PENGGUNAAN ANTIINFLAMASI NON-STEROID (OAINS) PADA RHEUMATOID ARTHRITIS DI RSUD DR. MOEWARDI SURAKARTA TAHUN 2020-2023 Adhi Wardhana Amrullah; Mawalida Mawalida; Rolando Rahardjoputro
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 1 (2025): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i1.244

Abstract

Rheumatoid arthritis (RA) is an autoimmune disease that attacks the joints with common symptoms such as pain and inflammation of the joints. Pain occurs due to damage to body tissue or potential damage. Complaints of pain in RA are generally treated with non-steroidal anti-inflammatory drugs (NSAIDs). However, the challenge in the use of NSAIDs is the irrational use of drugs. Irrational use of NSAIDs can cause inefficient and ineffective treatment. Therefore, it is necessary to conduct a study of the rationality of the use of NSAIDs in RA patients. This study was conducted to determine the level of rationality at Dr. Moewardi Surakarta Hospital in 2020-2023. The rationality study starts from the correct diagnosis, correct indication of the disease, correct drug, correct dose, correct route of administration and correct interval in non-steroidal anti-inflammatory drugs (NSAIDs) so that they do not cause side effects for patients. This study is a qualitative descriptive observational study using a cross-sectional design. The sample used is retrospective data obtained from patient medical records using a purposive sampling technique. The results of the analysis were carried out on 100 patient medical record data, the data was analyzed for rationality using the 6T method. The results of the analysis were that the correct diagnosis was 100.00%, the correct indication was 100.00%, the correct drug was 85.00%, the correct dose was 100.00%, the correct interval was 100.00%, and the correct route was 96.00%.
MODIFIKASI PELARUT DALAM ISOLASI DAN IDENTIFIKASI EUGENOL MINYAK CENGKEH (Oleum caryophyli) Diyan Sakti Purwanto; Iin Suhesti; Dina Ashfa Karima
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 1 (2025): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i1.245

Abstract

Clove oil (Oleum caryophyli) is an essential oil obtained from the distillation of clove flower buds. The main components of clove oil are terpenes and their derivatives. The main terpenes of clove oil are eugenol (60-90%), eugenol acetate, and caryophyllene. Eugenol has a refreshing and spicy aroma so it can be a component to freshen the mouth. In this study, the solvent modification between ethanol and ether was carried out in identifying and isolating clove oil eugenol. The results of organoleptic observations on ethanol solvents showed a dark yellow solution color while on diethyl ether it was clearer. Eugenol is a colorless, odorless, hard liquid with a spicy taste. Eugenol will easily turn brown when in open conditions. In the isolation process, diethyl ether is better at isolating eugenol. The yield obtained in the isolation process was 39.3%. From the TLC test, the Rf value 0.8 was obtained where the longer the spots, the greater the Rf value on the TLC plate, which means that more compounds are attracted. The results of the isolation and identification of eugenol show that diethyl ether solvent is more effective in the process of isolating clove oil eugenol.
FORMULASI KRIM EKSTRAK DAUN KELOR (Moringa oleifera Lam) dan CERAMIDE COMPLEX® SEBAGAI PELEMBAP Firhani Anggriani Syafrie; Rismayanti Rismayanti; Rina Andriani; La Ode Muhammad Fitrawan
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 1 (2025): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i1.249

Abstract

Moringa leaves are recognized for their high nutritional value and potential use in health and beauty products. Due to their moisturizing, antioxidant, and anti-aging benefits, moringa leaf extract is widely incorporated into skincare formulations. Ceramide Complex plays a key role in strengthening the skin barrier by retaining moisture and preventing dryness. This study aimed to examine the impact of different concentrations of moringa leaf extract on cream formulation characteristics and to assess its moisturizing effectiveness. The methodology involved maceration extraction of moringa leaves, phytochemical screening, cream formulation, and evaluation of its physical attributes. Results indicated that the maceration method successfully extracted 18.6% yield from moringa leaves, which were found to contain alkaloids, flavonoids, saponins, tannins, and steroids. The extract was effectively incorporated into cream formulations, with 3% extract concentration showing optimal moisturizing effects. The final cream passed several evaluation tests, including organoleptic assessment, homogeneity, pH, viscosity, spreadability, adhesion, cycling stability, moisturizing efficacy, irritation testing, and user preference.
UJI TOKSISITAS SUBKRONIK EKSTRAK TERPURIFIKASI DAUN PACAR KUKU (Lawsonia inermis L.) TERHADAP HATI TIKUS Fitriani W. Alani; Rismawati Rismawati; Mus Ifaya; Armayani Armayani
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 1 (2025): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i1.251

Abstract

Pacar Kuku plant (Lawsonia inermis L.) has the main content of active compounds such as flavonoids, glycosides, alkaloids, phenols, essential oils, and glycosides. The most active compounds found in Pacar Kuku leaves are phenols and flavonoids. Pacar Kuku leaves have many pharmacological activities including antimicrobial activity, diabetes mellitus treatment, cytotoxic, antiviral and wound healing effects. The purpose of this study was to determine the subchronic toxicity of purified extract of henna leaves by looking at the histological picture of the liver and symptoms of toxicity in mice. The method of this study was that the experimental animals were divided into 4 groups. The division of treatment groups is as follows: Group 1 as the control group was given Na. CMC 1%, groups 2 to 4 were given purified extract of Pacar Kuku leaves with dose variations of 250 mg / KgBW, 500 mg / KgBW and 1000 mg / KgBW given for 28 days. For 28 days, the animals were observed for toxicity symptoms such as respiratory rate, fatigue, body movement, fur appearance, gait, trembling, saliva production, and urination frequency and histopathological analysis of the heart was performed on the 28th day. Administration of purified extract of Pacar Kuku leaves at doses of 250 mg/kgBW, 500 mg/kgBW and 1000 mg/kgBW did not cause toxicity symptoms but affected the histopathological picture of the liver in mice which was characterized by cell damage in the form of necrosis, fatty degeneration and hydropic degeneration in each treatment group.
ANALISIS INTERAKSI OBAT PADA PASIEN COVID-19 DENGAN PENYAKIT ASMA DI INSTALASI RAWAT INAP RSD GUNUNG JATI trisna lestari; Lilis Kholida Nuiah; Aan Junaedi
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 1 (2025): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i1.252

Abstract

Covid-19 with treatment of asthma must be considered. Because comorbid patients experience polypharmacy, this study aims to determine patient profiles, drug interactions based on mechanism,severity and significance of the use of Covid-19 drugs with asthma comorbidities at the inpatient installation of RSD Gunung Jati Cirebon.This study is a non eksperimental study with retrospective data collection, namely medical record data of patients with confirmed Covid-19 with comorbid asthma. Sampling using total sampling technique as many as 51 medical records. The study was conducted from November 2022 ti July 2023. Determination of drug interactions using the drugs.com application. Descriptive statistical data analysis in the form of percentages and tables. Based on the result of a study of Covid-19 patients with comorbid asthma, the age group was dominated by the group of 46-55 years (31%) and the gender of 32 patients (62%) was female. There were 14 potential drug interaction events from 51 patienst with a pharmacodynamic mechanism of action in 31 cases (91,18%) and pharmacokinetics in 3 cases (8,82%). Based on the level of severity, namely 7 cases (20,59%) for major interactions, 21 cases (61,76%) for moderate, 6 cases (17,65%) for minor. Covid-19 drug interactions with asthma comorbidities are mostly pharmacodynamic mechanism and moderate in severity.

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