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Vania Snatika Putri
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INDONESIA
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat
Published by Politeknik Indonusa Surakarta
ISSN : 25486667     EISSN : 27759032     DOI : 10.46808
Core Subject : Health, Science,
Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health
The journal includes various fields of pharmaceuticals sciences such as: Pharmacy, Pharmacokinetics, Community and Clinical Pharmacy, Medical, Alternative medicines, Synthetic Organic Chemistry, Organic Chemistry of Natural Material, Biochemistry, Chemical Analysis, Microbiology, Tissue Culture, Botany and Animals Related to Pharmaceutical Products, Midwifery, Health Analyst, Nutrition and Public Health, Pharmacology and Toxicology
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 162 Documents
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FORMULATION AND ANTIOXIDANT ACTIVITY TEST OF SERUM COMBINATION OF MINT LEAVES ATTENTIVE OIL (Mentha piperita L.) AND SPRING FLOWER ATTENTIVE OIL (Clitoria ternatea L.) DPPH METHODS Aulia Prastika Maharni; Bangkit Riska Permata; Tatiana Siska Wardani
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.268

Abstract

Mint (Mentha piperita L.) contains key compounds such as menthol and menthone, which have strong antioxidant activity. Butterfly pea flowers (Clitoria ternatea) contain phenolic compounds, flavonoids, anthocyanins, and flavonol glycosides as antioxidants. This study aimed to determine the physical quality of serum preparations and the antioxidant activity of a serum combination of mint leaf essential oil (Mentha piperita L.) and butterfly pea flower essential oil (Clitoria ternatea L.) using the DPPH method. The results of the physical testing of the serum preparations showed that serum formulas F0, F1, F2, and F3 met good physical quality test standards. The antioxidant activity test results for the serum preparation combination of mint leaf essential oil and butterfly pea flower essential oil were as follows: Formula 0 (567.256 ppm), Formula 1 (141.007 ppm), Formula 2 (69.506 ppm), and Formula 3 (133.769 ppm).
UJI SUN PROTECTION FACTOR (SPF) DAN AKTIVITAS PEREDAMAN RADIKAL BEBAS PADA HIDROSOL KAYU MANIS (Cinnamomum verum) Aptika Oktaviana Dewi; Hana Aidah; Arriyana Putri Adisti; Fais Ifadah; Zulfa Citra Azzahro
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.269

Abstract

Cinnamon hidrosol (Cinnamomum verum) is a byproduct of the distillation process that has potential as an antioxidant and sunscreen, but is still rarely utilized. This study aims to determine the phytochemical content, sunscreen activity (SPF), and antioxidant activity of cinnamon hidrosol. Hidrosol was obtained by distillation for 4 hours with a ratio of material and solvent 1:3.5. Phytochemical tests were carried out qualitatively, SPF activity testing was carried out using the UV-Vis spectrophotometry method, and antioxidant activity testing used the DPPH method. The results showed that hidrosol from the distillation flask contained alkaloids, saponins, and phenolics, while from the distillate flask contained flavonoids, alkaloids, and phytosterols. The SPF test results showed the highest value in the distillation flask hidrosol of 39.78 which is included in the ultra protection category. The results of the antioxidant activity test showed an increasing % inhibition with increasing concentration, with an IC₅₀ value of the distillation flask hidrosol of 310.77 µg/mL (very weak category). In conclusion, cinnamon hidrosol has potential as a natural sunscreen ingredient, despite its relatively weak antioxidant activity. Therefore, it can be used as an additive in cosmetic products.
UJI SUN PROTECTION FACTOR (SPF) DAN AKTIVITAS PEREDAMAN RADIKAL BEBAS PADA EKSTRAK TEMU PUTIH (Curcuma zedoaria) Aptika Oktaviana Dewi; Laurentcia Filliks Rikumahu; Rifa Pasha Azzahratunnisa; Prima Khusnul Khotimah; Intan Aprilia; Ismah Rosydah
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.270

Abstract

White turmeric (Curcuma zedoaria. Rosc) is a medicinal plant that belongs to the Zingiberaceae family and is part of the Curcuma genus. The rhizome of white temu contains more than 10 sesquiterpenes, such as curcumin, ethyl p-methoxycinnamate, β-turmerone, and others. The extract of temu lawak contains flavonoids, terpenoids, saponins, and alkaloids. White temu has potential as an antioxidant and sunscreen, but it is still seldom optimally utilized. This study aims to evaluate the Sun Protector Factor (SPF) value and the ability of white turmeric extract (Curcuma zedoaria. Rosc) to scavenge free radicals. The extraction was performed by maceration using 70% ethanol as a solvent at a ratio of 1:10. Phytochemical screening results indicate the presence of alkaloids, flavonoids, phenolics, and phytosterols in the extract. The SPF test was conducted in vitro using a UV-Vis spectrophotometer through the Mansur method, obtaining an SPF value of 16.17 at a concentration of 500 ppm and 30.98 at a concentration of 1000 ppm, which falls into the ultra protection category. The antioxidant activity test was conducted using the DPPH method at a maximum wavelength of 515 nm, with the highest percentage inhibition reaching 80% at a concentration of 500 ppm. The obtained IC50 value is 93.43 ppm. These results indicate that white temu extract has potential for development as an active ingredient in natural sunscreen and also as an antioxidant.
STUDI LITERATUR LIMBAH OBAT RUMAH TANGGA Dwi Subarti; Rani Tiara Desty; Dessy Ratnasari
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 10 No. 1 (2026): Juni
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v10i1.273

Abstract

This study employed a descriptive qualitative approach through literature review to examine household pharmaceutical waste disposal pathways and their impacts on aquatic environments. Using the PICO framework, the review focused on Indonesian households (P) practicing improper disposal methods such as trash bins or drainage systems (I), compared to safe practices like take-back programs (C), with outcomes including water contamination and antimicrobial resistance (O). The literature selection followed the PRISMA flowchart, screening over 500 articles from Google Scholar, PubMed, and Scopus (2017-2025) to yield 30+ relevant sources. Findings revealed that over 70% of respondents dispose of medications improperly, leading to pharmaceutical residues (antibiotics, analgesics) detected in groundwater and rivers, posing risks to aquatic ecosystems and human health. Recommendations include intensive pharmacist-led education and national medication return programs to mitigate environmental risks.
GAMBARAN TINGKAT PENGETAHUAN TENTANG PENGGOLONGAN OBAT DAN JAMU PADA IBU-IBU PKK DI KABUPATEN KLATEN Dwi Subarti; Sunarmi
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.274

Abstract

Medicine is an essential need for the community, especially when experiencing illness. However, it is not uncommon for people to be reluctant to see a doctor when they are sick and instead prefer to buy medicine directly from a kiosk or pharmacy. According to the Guidelines of the National Drug Laboratory of Indonesia, medicines to be circulated in Indonesia must undergo evaluation regarding their efficacy, safety, and quality in accordance with applicable regulations. Medicines are classified into four main categories: over-the-counter drugs, limited over-the-counter drugs, prescription drugs, and narcotics. Information about this classification is important for the public to ensure proper and safe use of medicines. This study is observational and descriptive using a cross-sectional approach. The study involved community service activities conducted in Klaten Regency through lectures, simulations, and demonstrations accompanied by questionnaires. The results showed that the majority of respondents, who are PKK mothers in Klaten Regency, have a high school education background, totaling 13 respondents or 43%, while those with junior high school education are the smallest group with 3 respondents or 8%. Regarding occupation, the largest group is housewives, with 18 respondents or 60%, while professions such as midwives, civil servants, and general practitioners make up 23% of the respondents. The pre-test knowledge level showed that 10 respondents (33%) were in the good category, while 20 respondents (67%) were in the very good category.
PENGARUH SEDIAAN GEL EKSTRAK KULIT KAYU MATOA (Pometia pinnata) TERHADAP LUKA MEMAR PADA PAHA TIKUS (Rattus norvegicus) Mahmud Sulthon Khoiruzaman; A. M. Muslihin; Ratih Arum Astuti
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.275

Abstract

Matoa is a plant endemic to Papua, has antioxidant properties in its bark, which has the potential to treat bruises, a health problem that requires convenient product innovation. Thus, this study aims to test the effectiveness of matoa bark extract gel (Pometia pinnata) on bruises in white mice. This study is a quantitative experimental study. The gel was tested at extract concentrations of 1.5%, 3%, and 4.5%. Wound measurements were carried out using calipers, and observation notes were analyzed using two types of statistical tests: two types of paired and independent sample T-tests. The results showed that matoa bark extract contains saponins and flavonoids as antioxidants, anti-inflammatories, terpenoids that function as collagen stimulants. All treatment groups showed a significant healing effect. Gel concentrations of 3% and 4.5% gave significant results, although the 3% gel did not provide an effect equivalent to the positive control. The 1.5% gel had the same effect as the negative control. In conclusion, matoa bark extract gel with concentrations of 3% and 4.5% had a significant effect on healing bruises, although the 3% concentration of matoa bark extract gel did not provide an effect equivalent to the positive control.
EVALUASI PENYIMPANAN OBAT DI PUSKESMAS SAWIT BOYOLALI Riyan Setiyanto; Aptika Oktaviana Trisna Dewi; Ota Fiya Fatmi
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.276

Abstract

Drug stock storage serves to maintain the quality of drug preparations, guarantee drug availability, and facilitate the search and monitoring of stock supplies. Drug storage is an important factor in drug management at the health center, because with proper drug storage it will be easier and more effective to collect drugs and health services can be carried out properly. This study aims to determine the results of the evaluation of drug storage in the pharmaceutical installation of the Sawit Health Center, Boyolali. The method used in this study is descriptive observation. Observations were carried out using a checklist sheet containing drug storage indicators, both in the pharmaceutical installation and in the pharmacy warehouse. Observations were carried out using a checklist sheet to compare the actual drug storage conditions with the established indicators. Based on the results of the study that has been conducted at the Sawit Health Center, it can be concluded that the level of suitability of drug storage at the Sawit Health Center in the warehouse section is 80.95%, which is included in the very good category, and the suitability of drug storage at the Sawit Health Center in the pharmacy section is 100%, which is included in the very good category. The average percentage of drug storage at the Sawit Health Center pharmacy installation is 90.47%, which is included in the very good category.
KAJIAN PENGGUNAAN TANAMAN HERBAL DI KALIMANTAN UNTUK MENDUKUNG PRODUKSI ASI PADA IBU MENYUSUI Shahiroh Haulaini
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.280

Abstract

Indonesia's tropical climate nurtures a rich biodiversity, including various herbal plants that can enhance maternal and infant health. A significant focus of the government is addressing the low rate of exclusive breastfeeding, which contributes to stunting in children. This study explores herbal plants in Kalimantan that serve as galactagogues, promoting breast milk production in nursing mothers. Research was conducted using academic databases like Scopus, PubMed, and Google Scholar, resulting in five comprehensive scientific articles. The literature review highlights several plants known to increase breast milk production, such as Moringa oleifera (moringa), Curcuma domestica (turmeric), Stenochlaena palustris (kelakai), and a blend of soy milk and dates. Additionally, plants like Chenopodium sp. (village spinach), Ipomoea batatas (sweet potato), and Ocimum basilicum (basil) have shown promising results. Many of these plants are easy to cultivate in home gardens, offering natural solutions to support exclusive breastfeeding initiatives in Indonesia. Utilizing local Kalimantan herbal plants presents an effective alternative for enhancing maternal and infant health and holds potential for further application in the medical field.
FORMULASI, EVALUASI, DAN OPTIMASI MASKER GEL PEEL-OFF MINYAK PEPPERMINT DENGAN VARIASI HPMC K4M DAN CARBOPOL 940 MENGGUNAKAN DESAIN FAKTORIAL Alinda Tania; Andhina Pramesty; Sonata Daniatiek
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.281

Abstract

Facial skin requires protection from environmental pollutants and ultraviolet exposure that can cause premature aging, acne, and dryness. Peel-off gel masks are practical cosmetic preparations that moisturize, revitalize, and can be easily removed after use. Peppermint oil (Mentha piperita L.) has cooling, antibacterial, and antioxidant properties, making it beneficial for oily and acne-prone skin. This study aimed to formulate and optimize a peppermint oil peel-off gel mask using Hydroxypropyl Methylcellulose (HPMC) K4M and Carbopol 940 as gelling agents and to evaluate its physical properties. A factorial design was applied with four combinations of HPMC K4M (2–4%) and Carbopol 940 (0.5–1%). Physical evaluations included organoleptic properties, homogeneity, pH, adhesion, drying time, and viscosity. Data were analyzed using Stat-Ease 360 software version 22 to determine the optimum formula. Increasing gelling agent concentrations decreased pH but increased viscosity, adhesion, and drying time. The optimum predicted formula was obtained at 2.75% HPMC K4M and 0.9793% Carbopol 940, showing desirable physical characteristics. The peppermint oil peel-off gel mask formulated with HPMC K4M and Carbopol 940 met the physical quality requirements. Factorial design optimization proved effective in determining the ideal formulation composition for optimal mask performance.
UJI STABILITAS FISIK DAN PENETAPAN KADAR FENOLIK SEDIAAN KRIM EKSTRAK ETANOL HERBA BANDOTAN (Ageratum conyzoides L.) Disa Andriani; Salva Fellia Rahmawati; Nastiti Utami
Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Vol. 9 No. 2 (2025): Desember
Publisher : Politeknik Indonusa Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46808/farmasindo.v9i2.283

Abstract

Bandotan (Ageratum conyzoides L.) is a wild plant that grows quickly and thrives in various types of soil. Bandotan contains various metabolite compounds, one of which is phenolic compounds. This study aims to obtain a stable cream preparation by varying the concentration of stearic acid and triethanolamine (TEA) to obtain an optimal formulation. The cream was formulated with varying concentrations of stearic acid of 18%, 19%, and 20%, and TEA of 3%, 2.5%, and 2%. Stability evaluation was carried out using the cycling test method which includes organoleptic tests, homogeneity, pH, adhesiveness, spreadability and viscosity. The results showed that the ethanol extract of bandotan herb containing phenolic compounds with all variations of stearic acid and TEA concentrations met the test requirements and did not show differences in organoleptic, homogeneity, pH, adhesiveness, spreadability and viscosity. Statistical test results indicate that the cream preparation is physically stable, as there was no significant difference between the cream preparation before and after the cycling test, but there was a significant decrease in phenolic content.

Page 13 of 17 | Total Record : 162

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