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Rina Priastini Susilowati
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Gedung A Lantai 1, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Kristen Krida Wacana Jl. Arjuna Utara No. 6, Duri Kepa, Kebon Jeruk, Jakarta Barat, Jakarta 11510
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Jurnal MedScientiae
Published by Universitas Kristen Krida Wacana
ISSN : -     EISSN : 28291166     DOI : https://doi.org/10.36452/jmedscientiae
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Jurnal MedScientiae adalah jurnal yang dikelola oleh Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana. Jurnal ini mempublikasikan artikel-artikel secara open access dalam lingkup bidang kedokteran dan kesehatan seperti kedokteran dasar, bioetika kedokteran, biologi sel, biologi molekuler, genetika, fisiologi, biokimia, bioinformatika, anatomi, farmakologi, kesehatan masyarakat, dan ilmu biomedik lainnya. Tim editorial menerima naskah berupa artikel penelitian, literature dan systematic review, dan laporan kasus. Naskah yang dikirimkan hendaknya belum pernah diterbitkan sebelumnya di jurnal maupun media yang lain dan disiapkan sesuai dengan template atau format yang telah ditentukan. Setiap naskah yang memenuhi kriteria jurnal akan direview oleh pakar yang sesuai (peer reviewer). Jurnal MedScientiae tidak mengenakan biaya selama proses mulai dari penerimaan naskah hingga publikasi. Jurnal MedScientiae terbit 3 kali dalam satu tahun, yaitu pada bulan April, Agustus dan Desember dengan cakupan keilmuan yang telah disebutkan di atas. Edisi pertama jurnal akan diterbikan di bulan Mei tahun 2022 dengan nomor ISSN 2829-1166.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 13 Documents
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Search results for , issue "Vol. 4 No. 1 (2025): April" : 13 Documents clear
Deskripsi Profil Pasien Baru Vitiligo di Rumah Sakit Umum Daerah Tarakan Jakarta Periode Tahun 2023 Irviani, Irviani; Hapsari, Saskia Retno Ayu
Jurnal MedScientiae Vol. 4 No. 1 (2025): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i1.3679

Abstract

Vitiligo caused by depigmentation process manifested as white macules and patches on body with prevalence about 0.5-2% of world populations and classified as non-segmental, segmental, and unclassifiable forms. The therapies include PUVA, NBUVB, topical corticosteroid, laser, and other topical therapies. Vitiligo patients of Tarakan Regional Hospital in 2022 were 9,199 and in 2023 were 10,385. This study was conducted to understand the description of new vitiligo patients profile at Tarakan Regional Hospital as comprehensive data to provide better therapy. The study design used descriptive retrospective study of new vitiligo patients at Tarakan Regional Hospital in 2023 with consecutive sampling from electronic medical record. New vitiligo patients at Tarakan Regional Hospital in 2023 were 105 patients. Majority was women total 58 patients (55.24%), largest age groups were 21-30 years old and 41-10 years old consist of 18 patients each group (17.14%), most frequent lesion is multiple in 98 patients (93.33%), most frequent location is face area of 67 patients (63.81%), most frequent type is vitiligo vulgaris in 87 patients (82.86%), and majority doesn’t have any comorbidities found in 92 patients (87.62%). The new vitiligo cases at Tarakan Regional Hospital in 2023 was 105, majority was women, multiple lesions, and vitiligo vulgaris.
Prevalensi Efek Prisma Pada Mahasiswa Pengguna Kacamata Koreksi Di FKIK UKRIDA Angkatan 2023 Kencana, Billy Gadi; Far Far, Inggrid Osya; Silaen, Desi Hartati
Jurnal MedScientiae Vol. 4 No. 1 (2025): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i1.3685

Abstract

Prism effect occurs when light rays decentration from the optical center point. Prism effect without prescription is called unwanted prism. This study aims to determine the prevalence of the prism effect in students who wear corrective glasses. This study used a quantitative descriptive method with a cross-sectional design on 78 respondents. Data collection was carried out from September 2023 to October 2023. In this study, 71.8% (56 people) of respondents were female. As many as 52.6% (41 people) of respondents used spherocylinder lenses. The resultant horizontal and vertical prism effects were highest in the 0.00–1.00∆D category, 70.5% (55 people) and 91% (71 people). The most resultant prism base directions at the Base In & Base Down directions as much as 38.5% (30 people). The horizontal prism effect is still within tolerance of 65.4% (51 people) and the vertical prism effect is still within tolerance of 70.5% (55 people). The prevalence of students experiencing the prism effect reached 93.4%. However, most of it within tolerance limits, horizontal 65.4% and vertical 70.5%. It is recommended for optometrists to prescribe glasses and ensure that the glasses have gone through the correct steps to avoid unwanted prism effects.
The Role of Flavonoids as Immunomodulatory Agents: Therapeutic Potential and Mechanisms of Action Sabini, Jasmine Harumi; Susilowati, Rina Priastini; Sari, Monica Puspa
Jurnal MedScientiae Vol. 4 No. 1 (2025): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i1.3710

Abstract

Flavonoids are a group of polyphenolic compounds widely found in plants and have long been recognized for their biological activities, including antioxidant and anti-inflammatory effects. In recent years, increasing attention has been given to the potential of flavonoids as immunomodulatory agents. This review article aims to summarize and evaluate scientific evidence regarding the role of flavonoids in modulating both innate and adaptive immune responses. Several flavonoids, such as apigenin, genistein, quercetin, and naringenin, have been shown to suppress the production of proinflammatory cytokines, inhibit macrophage activation, and influence the differentiation of T cell subpopulations such as Th1, Th2, Th17, and Treg. In addition, some flavonoids have been found to inhibit inflammasome activation and may promote macrophage polarization toward either the M1 or M2 phenotype depending on the pathological context. Although preclinical data demonstrate promising results, challenges such as low bioavailability remain a major barrier to therapeutic application. Therefore, further research is needed to optimize the clinical potential of flavonoids as effective and safe immunomodulatory agents.

Page 2 of 2 | Total Record : 13

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