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Rizal Irfandi
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rizalirfandi043@gmail.com
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Jl. Bumi 18 Blok A 15 No. 1 Bumi Permata Hijau, Makassar, Sulawesi Selatan, Indonesia
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Kota makassar,
Sulawesi selatan
INDONESIA
Hayyan Journal
Published by Education and Talent Development Center Indonesia
ISSN : -     EISSN : 30466679     DOI : https://doi.org/10.51574/hayyan.v1i1.1130
Core Subject : Health, Science, Engineering,
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Engineering Medicine & Pharmacology
Focus and Scope This journal publishes articles related to chemistry. The scope of this journal includes: Inorganic Chemistry Organic Chemistry Physical Chemistries Chemical Instruments Analytical Chemistries Materials Chemicals Industrial chemistry Biochemistry Applied Science Applied Chemistry
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 11 Documents
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Search results for , issue "Vol. 2 No. 1 (2025): February" : 11 Documents clear
Literature Review on Chemical Compounds from Natural Ingredients that Function as Anti-Hypertension Nur, Andi Bulqiah
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.2479

Abstract

Hypertension is one of the most common health problems worldwide and is a major risk factor for cardiovascular diseases such as coronary heart disease and stroke. Many synthetic drugs are available to manage hypertension, but they often have significant side effects. Research on chemical compounds from natural materials that have antihypertensive activity is very important. This literature review aims to evaluate various chemical compounds that are derived from natural materials and have potential as antihypertensive agents. Some of the plants that have been identified as having active chemical compounds include Hibiscus sabdariffa which contains anthocyanins, Allium sativum (garlic) which contains allicin, and Andrographis paniculata which contains andrographin. Recent studies have shown that these compounds are effective in lowering blood pressure through various mechanisms such as vasodilation, diuresis, and inhibition of angiotensin-converting enzyme (ACE). This study highlights the importance of using natural ingredients as a safer and more effective alternative to synthetic drugs for the management of hypertension. However, more research is needed to develop more effective drug formulations and to test their effectiveness clinically in human populations.
Comparison of Eosin, Physiological Saline and Lugol Solutions by Using A Native Method for Detection of All Soil-Transmitted Helminths (STH) Kaswi, Nurwilda
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.2662

Abstract

Stunting can be caused by worm disease because it will interfere with the absorption of nutritional intake, especially carbohydrates and protein, in children. World Health Organization (WHO) data in 2021 reported 24% of the world’s population was infected by Soil Transmitted Helminths (STH). Worms belonging to STH are Ascaris lumbricoides, Trichuris trichiura and hookworms (Ancylostoma duodenale and Necator americanus). The diagnosis of intestinal worms is confirmed by microscopic examination of the feces supported by staining. This study aimed to explore and identify eosin, lugol and physiological saline and evaluate their chemical content as staining solutions to prepare stool samples. A total of 5 stool samples divided into 15 microscopic glass slide were successfully obtained from children around Politeknik Muhammadiyah Makassar. Ascaris lumbricoides was most prevalent helminth found in observations by all the three methods (eosin, lugol and physiological saline wet mount preparation). It was also observed that the young (1-10 years) were more infected because we took samples from childrens around the campus Politeknik Muhammadiyah Makassar. However all the three methods, eosin was found to be effective in coloring the egg stage of the STH parasites. Eosin for wet mount smear in examining the stool samples for detection of intestinal helminths may be routinely used which is simple, clarifying observations under the microscope and increasing the contrast between stained worm eggs and the background because these dye is an acidic compound that is able to fluoresce because it contains bromine and fluorescein so that it can color the cytoplasm and provide a contrast effect so that the boundaries between cells can be observed clearly.
In Silico Studies and Admet Predictions Diterpenoid Compound Andrographis paniculata (Burm.f.) Nees as Inhibitor of Streptococcus mutans Nurfadillah, Arafah; Amir, Nur Insani; Ramadhani, Sindi
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.2679

Abstract

Andrographis paniculata (Burm.f.) Nees are reported to have many bioactivities, including antibacterial, hepatoprotective, antimalarial, antihypertensive, antipyretic, antithrombolytic, and other pharmacological effects. This study aims to determine the benefits of the active compound Andrographis paniculata in inhibiting the activity of the enzyme glucosyltransferase. This research method was carried out in silico on 3AIC receptors using Chimera, ChemDraw Ultra 12.0, MGLtools, Autodock4, Biovia Discovery Studio, and Toxtree software. The results showed that of the 12 test compounds, the AP11 compound has the lowest ∆G free bond energy of -8.5KKal/mol, lower than natural ligands, and more hydrogen bonds than natural ligands, MES. Therefore, it can be concluded that the AP11 compound has the most potential to inhibit glucosyltransferase receptors
The Effect Of Giving Olive Oil On Diaper Rash In Toddler In The Work Area Ponre Health Center Year 2024 Sari, Iramaya; Nabila, Nabila
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.2788

Abstract

Babies have extensive and complex problems, especially skin problems. All babies have very sensitive skin. The relatively thinner skin conditions in babies cause babies to be more susceptible to infections, irritation and allergies. Skin disorders that often arise in babies include atopic dermatitis, seborrhea, boils, miliariasis (diarrhea), allergies, and inflammation in the form of a skin rash known as diaper rash. The aim of this research is to determine the effect of giving olive oil on diaper rash in toddlers in the Ponre Health Center working area in 2024. This research is a type of quasi-experimental research with a pretest-posttest control group design. Data analysis used univariable and bivariable analysis with the chi-square test. The research results showed that the experimental group showed a decrease in the average score from 2.08 (moderate) to 1.33 (mild) after administering olive oil. Meanwhile, in the control group, the average score only fell slightly from 2.09 to 2.02. Based on the chi-square test in the experimental group, it was found that the value of p=0.001<0.05 and based on the chi-square test in the control group, the value was found to be (p=0.112>0.05), which means that there is an effect of giving olive oil on diaper rash in toddlers. The conclusion of this research is that there is an effect of giving olive oil on diaper rash in toddlers in the work area of ​​the Pontre Community Health Center in 2024
Comprehensive Midwifery Care For Ny’’H’’ With Normal Pregnancy At Bontobangun Health Center,Rilau Ale District,Bulukumba Regency Asririn, Asririn; Juniarli, Sri Eka; Irmawati, Irmawati
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.2789

Abstract

Midwives play an important role in efforts to improve maternal and child health, one of which is by implementing comprehensive midwifery care. Midwifery care is carried out to detect early things that may occur during pregnancy, childbirth, newborns, postpartum, neonates and family planning services. The aim is to provide comprehensive care to Mrs "H" aged 25 years from pregnancy, childbirth, postpartum, newborn, and contraceptive services. The method used in providing comprehensive midwifery care is a case study with a Varney management approach with data collection techniques including observation, interviews, physical examination and documentation studies. Results of comprehensive midwifery care for Mrs. , male gender, postpartum progress is normal and the contraception you want to use after the postpartum period is the birth control implant. Conclusion: Comprehensive midwifery care for Mrs "H" was carried out according to standards of care. Carried out according to standards of comprehensive midwifery care that is running normally.
Description of Calcium Oxalate Crystals in Urine Based on Degree of Dehydration Syamsinar, Syamsinar; Aryandi, Rahmat; AB, Azsrul; Islawati, Islawati
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.2792

Abstract

Dehydration is a condition of lack of body fluids because the amount that comes out is more than the amount of fluid that goes in, water output must be balanced with water intake, if there is an imbalance of fluids in the body, dehydration will occur. Reducing fluid consumption means the body will automatically experience dehydration, this dehydration will trigger a constant decrease in urine volume. Urine volume indicates insufficient water in the body dissolving minerals and urine. If there is not enough fluid in the urine, the bound oxalate and calcium will collect and form stones. The formation of stones is directly related to lack of fluid intake in the body. The formation of calcium oxalate crystals can cause kidney stones. Oxalate can precipitate and form calcium oxalate which cannot be absorbed by the body, resulting in insoluble salt deposits forming which cause kidney disease. In the body, oxalate will combine with calcium to form calcium oxalate crystals. To determine the appearance of calcium oxalate crystals in urine, the degree of dehydration. This type of research is qualitative research using the microscopic method. The population in this study were students, etc. Medical laboratory technology, Stikes Panrita Husada Bulukumba. There were 45 samples, 15 samples of mild dehydration, 15 samples of moderate dehydration, and 15 samples of severe dehydration. The sample in this study was a urine sample. Based on the research that has been carried out, results were obtained from 45 samples, 15 samples of mild dehydration, 15 samples of moderate dehydration, and 15 samples of severe dehydration. In severe dehydration, 1 sample was found that obtained a positive result (+) with a percentage of (6.7%).
Relationship Between Knowledge and Attitude of Breastfeeding Mothers in Providing Exclusive Breastfeeding at Pattingaloang Health Center Asmirah, Rika; Rahmawati, Rahmawati
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.2795

Abstract

The first thousand days of life are a golden period that greatly determines the optimal growth and development of children. Exclusive breastfeeding plays an important role in meeting the nutritional needs of infants and reducing morbidity and mortality rates in children. However, the coverage of exclusive breastfeeding has not yet reached the expected target. Various factors, including the level of knowledge and attitude of mothers, are thought to influence the success of exclusive breastfeeding. This study aims to analyze the factors that influence exclusive breastfeeding in infants over 6 months of age in the Pattingaloang Health Center work area, South Sulawesi. This study used a correlation analytic design with a cross-sectional approach. The sample in this study were 33 mothers who had infants aged 6–24 months and were selected using the total sampling technique. Data were obtained through questionnaires and analyzed using the Chi-square test with the help of SPSS. The results of the analysis showed that there was a significant relationship between the level of maternal knowledge and exclusive breastfeeding (p-value = 0.028). Mothers with good knowledge are more likely to provide exclusive breastfeeding than mothers with poor knowledge. Meanwhile, no significant relationship was found between the mother's attitude towards breastfeeding and exclusive breastfeeding (p-value = 0.532). In addition, age, education level, and occupation also contribute to the formation of maternal knowledge about exclusive breastfeeding. The level of maternal knowledge significantly influences the success of exclusive breastfeeding, while maternal attitudes do not show a significant relationship. Therefore, efforts are needed to increase education and counseling regarding the importance of exclusive breastfeeding, especially for mothers with low education levels or limited access to health information
The Effect of Efflurange Message on Reducing Labor Pain Intensity at Ujungloe Health Center Alinengsih, Wahyuni; Nabila, Nabila
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.2796

Abstract

Effleurage massage is one of the massages that can reduce the intensity of labor pain. Effleurage massage is done on the back area where massage in that area can relax the muscles, provide a peaceful rest and increase the comfort of the mother during labor. Gentle massage on the back area can play a role in reducing the intensity of labor pain. The purpose of this study was to determine the effect of effleurage massage on reducing the intensity of labor pain in mothers giving birth at the Ujungloe Health Center. This study is a type of quasi-experimental study with the design used is a pretest posttest one group design. This design has a pretest, before being given treatment with a total sample of 18 respondents using total sampling usingWilcoxon testsign rank test.The results of this study were obtained(p value = 0.000 <0.05) then it was found that there was a significant effect of giving effleurage massage in reducing labor pain, it was found that the frequency of back pain in mothers giving birth normally before effleurage massage, the most respondents felt moderate pain as many as 12 respondents (67%) and after effleurage massage, the most respondents felt mild pain as many as 15 respondents (83%). The conclusion of this study is that effleurage massage has an effect on reducing labor pain at the Ujungloe Health Center. This study is expected to provide benefits for the development of obstetrics, one waywhich can be done to reduce labor pain with non-pharmacological actions, furthermore, researchers are expected to provide training to midwives in health centers so that they can be more skilled in carrying out message efflurange to mothers in labor to reduce labor pain.
Review Article: Phytochemical Screening and Potential Biological Activities of Lahuna Plants ( Chromolaena odorata L.) Jumrah, Elfira
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.3129

Abstract

Chromolaena odorata L., locally known as the Lahuna plant, is a tropical plant with great potential in traditional medicine. This study uses a qualitative approach method that critically examines the results of previous studies on the phytochemical content and potential biological activity of the Chromolaena odorata L. plant. This review article discusses the results of phytochemical screening and the potential biological activity of various secondary metabolite compounds contained in the plant, such as flavonoids, alkaloids, saponins, tannins, and terpenoids. Various studies have shown that C. odorata has broad pharmacological activities, including antibacterial, anti-inflammatory, antioxidant, and wound-healing agents. With its abundant bioactive content, this plant has great potential to be developed as a source of natural medicine. However, its clinical use still requires further scientific validation through toxicity tests, pharmacodynamics, and clinical trials. This article aims to provide a scientific basis for the potential of C. odorata in the field of phytopharmaceuticals and encourage further research for its development.
Assessing Toxic Levels in Facial Creams from Burung-Burung Traditional Market, Gowa Salnus, Subakir
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.3373

Abstract

Facial cream is a skin care product that is widely used to improve appearance and overcome various skin problems. However, some unregistered products, especially those sold in traditional markets, can contain hazardous materials such as mercury. This study aims to identify the presence and levels of mercury in unregistered facial whitening creams sold in the Burung-Burung Traditional Market, Pattallassang District, Gowa Regency. Samples were analyzed using the Atomic Absorption Spectrophotometry (AAS) method. The results showed that five of the eight samples contained mercury exceeding the threshold set by BPOM RI, which is 1 mg/kg. This finding emphasizes the need for stricter regulation and supervision of cosmetic products to protect public health.

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