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Nanang Yunarto
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Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan Kementerian Kesehatan RI Jl. Percetakan Negara No. 23 - Jakarta 10560
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Kota adm. jakarta pusat,
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INDONESIA
Jurnal Kefarmasian Indonesia
Published by Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan
ISSN : 2085675X     EISSN : 23548770     DOI : -
Core Subject : Health, Science,
Chemistry Medicine & Pharmacology
Pharmaceutical Technology, Pharmacology, Pharmaceutical Chemistry, Traditional Medicines, and Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 7 Documents
 1 
Search results for , issue "VOLUME 4, NOMOR 2, AGUSTUS 2014" : 7 Documents clear
Toksisitas Akut dan Subkronis Ramuan Ekstrak Kelor dan Klabet sebagai Pelancar ASI dan Penambah Gizi Widowati, Lucie; Winarno, M Wien; Intan, Putri Reno
Jurnal Kefarmasian Indonesia VOLUME 4, NOMOR 2, AGUSTUS 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Insufficient breast milk intake from a mother to their babies may cause a poor infant growth. We have conducted a research on mixture of klabet seed extracts (Trigonella foenum-graecum L.) and kelor leaf extract (Moringa oleifera Lamk.) (1:1) for increasing breast milk production in nursing mothers and nutritional supplement for infants. The study is a completely randomized design. We used white rats (Rattus novergicus), Wistar strain, as many as 50, that were divided into 5 dose groups for the acute toxicity testing and 40 rats in 4 dose groups for the sub-chronic toxicity testing.The acute toxicity testing of fenugreek seed extracts and moringa leaf extracts (1:1) results in a pseudo value LD50 >4,000 mg/200g bw, therefore we classified the materials to practically non-toxic (PNT). For the subchronic toxicity testing, the result showed a normal state on liver and kidney function.
Isolasi dan Identifikasi Struktur Karotenoid dari Ekstrak Bayam Merah (Amaranthus Tricolor L.) Sulistyaningrum, Novi
Jurnal Kefarmasian Indonesia VOLUME 4, NOMOR 2, AGUSTUS 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Amaranthus tricolor L. was reported as source of carotenoid compounds (tetraterpenoids) which is a natural pigments and has bioactivity as antioxidants. They are beneficial to health. Carotenoids isolate are obtained by maceration method in methanol, saponification with KOH / MeOH 5%, fractionated by vacuum column chromatography, preparative thin layer chromatography (preparative-TLC) repeatedly and each fraction monitored using thin layer chromatography (TLC). Structure analysis of carotenoids based on UV, IR and GCMS spectroscopic data showed similarities as lutein structure.
Pengaruh Pemberian Fraksi Protein Ekstrak Kuda Laut (Hippocampus kuda Bleeker, 1852) terhadap Peningkatan Kadar Hemoglobin Mencit (Mus musculus L) Adam, Kindi; Fitria, Laksmindra; Sarto, Mulyati
Jurnal Kefarmasian Indonesia VOLUME 4, NOMOR 2, AGUSTUS 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Seahorse (Hippocampus kuda) is known to have a high concentration of iron, taurin and progesteron as testosteron precursor. Seahorse extract can increase the production of testosterone hormone of mice. On the erythrocytes development, kidney is stimulated to release erythropoietin hormone in case of hypoxia and also related with testosterone production. Erythropoietin control erythrocytes development and increase hemoglobin synthesis. The objective of experiment was to study the effect of seahorse extract as supplemented food in optimal concentration in range of 100, 200 and 300 mg/kg body weight on mice’s hematopoiesis and erythropoiesis. Each of treatment groups consist of 5 mices. The observed parameters were hematocrit value, hemoglobin concentration and renal index which observed on day 0, 34 and 67. The result showed that treatment of seahorse protein fraction extract until 300 mg/kg body weight dosage have no effect to the hematocrit value. The 200 mg/kg body weight extract dosage was able to increase the hemoglobin rate measurement. Renal index of Mice on day 34 and 67 after treatment did not give significant difference among treatment and control
Perbandingan Penggunaan Obat Rasional Berdasarkan Indikator WHO di Puskesmas Kecamatan antara Kota Depok dan Jakarta Selatan Kardela, Widya; Andrajati, Retnosari; Supardi, Sudibyo
Jurnal Kefarmasian Indonesia VOLUME 4, NOMOR 2, AGUSTUS 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Procurement and distribution of drugs to community health centers generally performed by health office districts, such as Depok City, but in the province of Jakarta conducted by the community health centers in sub district. The purpose of the study was to compare the rational drug use among community health centers in the district of Depok City and South Jakarta. This study used a cross-sectional design conducted in treatment and non- treatment community health centers in District X Depok City and district Y South Jakarta period MarchOctober 2011. Rational drug use data was collected in accordance with WHO procedure. Data was analyzed by Kruskal Walis test. Conclusion of the study shows that rational drug use based on prescribing indicators in community health centers in Depok City relatively better than South Jakarta, but no statistically significant (p> 0.05). Rational drug use based on patient care indicators in community health center South Jakarta is relatively better than Depok city, however, showed no statistically significant (p> 0.05). In contrast to the indicator of drug preparation time in health centers Depok relatively faster than South Jakarta, showed statistically significant (p
Optimasi Formula Tablet Salut Enterik Natrium Diklofenak dengan Bahan Penyalut Kollicoat 30 D Yunarto, Nanang
Jurnal Kefarmasian Indonesia VOLUME 4, NOMOR 2, AGUSTUS 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Diclofenac sodium is an analgetic and antiinflammation drug and commonly used by oral administration. Because of it’s side effects that can cause stomach irritation, nausea and vomiting, it’s made in the form of enteric-coated. Enteric-coated formulations developed used organic solvent having toxicity and flammability risks. The aim of this study is to develop diclofenac sodium enteric-coated tablets with a water-based coating material. Coating material used is Kollicoat 30 D which is a derivative of acrylic polymer that can dispersed in water. Optimalization of the formula is done by the weight gain 4%, 6% and 8%. The result showed that enteric coated tablets used coating material with weight gain 8% gave the best result with all parameters meet the requirements of the test, there was no change in acid medium for 2 hours and stable released active ingredient in alkaline medium.
Front Matter Volume 4 No 2 Tahun 2014 JKI, Editor
Jurnal Kefarmasian Indonesia VOLUME 4, NOMOR 2, AGUSTUS 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Back Matter Volume 4 No 2 Tahun 2014 JKI, Editor
Jurnal Kefarmasian Indonesia VOLUME 4, NOMOR 2, AGUSTUS 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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