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Fakultas Farmasi UMI, Kampus II UMI, Jl. Urip Sumoharjo No.225, Panaikang, Panakkukang, Kota, Makassar,, Panaikang, Kec. Panakkukang, Macassar, Sulawesi Selatan 90231
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MPSJ
Published by Universitas Muslim Indonesia
ISSN : -     EISSN : 29870887     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Makassar Pharmaceutical Science Journal merupakan salah satu jurnal yang dikelola oleh Fakultas Farmasi Universitas Muslim Indonesia yang terbit pertama kali pada bulan Maret 2023. Makassar Pharmaceutical Science Journal merupakan jurnal ilmiah yang terbit secara on-line dan menerbitkan artikel atau karya ilmiah hasil penelitian dalam bidang farmasi sains.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 20 Documents
 1   2 
Search results for , issue "Vol 2 No 1 (2024)" : 20 Documents clear
Sifat Fisik Farmaseutik Tablet Hisap Herbal Yang Menggunakan PVP K-30 Dan Gom Arab Sebagai Pengikat Haris, Zulfiah; Mirawati, Mirawati; Nurlina, Nurlina
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.168

Abstract

Tablets are pharmaceutical preparations that are most widely used by the public compared to other pharmaceutical preparations. One type of tablet is lozenges which are solid preparations containing one or more medicinal ingredients, generally with flavorful and sweet ingredients, which can make the tablet dissolve or disintegrate slowly in the mouth. Polyvinyl pyrylone K-30 (PVP K-30) binder has an advantage over other binders, as it can increase the hardness of tablets, making tablets a compact preparation. Arabic gum also has good flow properties, pharmacologically inert, has good compressibility and compactness. The purpose of the review is to determine the pharmaceutical properties of herbal lozenges that use PVP K-30 and Arabic gum as binders. The method used in reviewing this review is an electronic literature study by accessing journal search sites related to the keyword " PVP K-30 lozenges and gum arabic lozenges". Binder material as one of the ingredients needed in lozenges because the binder can determine the level of hardness, brittleness and destruction time of lozenges. PVP binders and gum arabic are examples of binders that have good flow properties and stationary angles, and for hardness PVP tablets are good binders, but if the concentration used is high then the brittleness level is reduced.
Analysis of Hydroquinone in Face Whitening Cream Circulating in Pinrang Regency Mustafa, Diyan Nurkhalisah; Aminah, Aminah; Widiastuti, Harti
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.172

Abstract

DIYAN NURKHALISAH M. Analysis of Hydroquinone in Face Whitening Cream Circulating in Pinrang Regency. (Supervised by Harti Widiastuti and Aminah). Whitening cream is a cosmetic preparation consisting of a mixture of chemicals and other ingredients that aims to whiten or fade black spots on the skin. Many people use whitening creams because they are sold freely. However, not all whitening creams that are sold freely are safe to use because they contain dangerous ingredients, such as hydroquinone. The purpose of this study was to analyze the hydroquinone compound in whitening cream circulating in Pinrang Regency and to find out how much hydroquinone it contained. Qualitative analysis of the four samples using the Thin Layer Chromatography (TLC) method positively contained hydroquinone which was indicated by the Rf values ​​of the samples and standard standards being the same and the appearance of purple spots which were detected under UV light of 254 nm. Quantitative analysis on four samples using the High Performance Liquid Chromatography (HPLC) method with a flow rate of 1 ml/minute, the mobile phase was methanol:aquabidestilata (55:45), the stationary phase was column C-18, the retention times of the sample and standard were obtained at the same value. namely 1.5 and 1.6 indicating that the sample contains hydroquinone. The linear regression equation y = 39.549x – 283.31 with a correlation coefficient of 0.998. The hydroquinone levels obtained were code A whitening cream of 2.5%; whitening cream B 2.8%; whitening cream C 2.45%; and whitening cream D by 0.9%.
Profil Penggunaan Obat Antihipertensi Pada Pasien Rawat Inap di RSUD La Temmamala Kabupaten Soppeng Nugraha, Akram Resa; Herman, Hendra; Purnamasari, Vina
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.178

Abstract

Hypertension has become one of the deadly diseases in both Indonesia and the world. Hypertension (or high blood pressure) is defined as a condition when the blood pressure is above 140/90 mmHg. According to the profile of the Health Department of South Sulawesi Province in 2018, Soppeng Regency has the highest rate of people with hypertension at 98,79% with 4.997 from 5.058 patients. The purpose of this research is to describe the usage of anti-hypertension medicines to the patients at Latemmalala Regional Public Hospital, Soppeng Regency, in the period between June-December 2022. This research is considered a quantitative research with the descriptive method and observational research design, as well as the retrospective approach that begins with the documentary research taken from the patient’s medical records. The result shows that the characteristic rate of the patients according to the gender is mostly found on females, with 20 patients being confirmed (67,5%), for the ages between 60-69 years old, 15 patients are confirmed (46,9%), and the following disease that is also found on the patients with hypertension is the kidney failure, where there are 14 patients being confirmed (20%). The most used type of medicine is the calcium channel blocker (CCB), another medicine that is also often used is the 57 units of amlodiphine (37,5%), and the most-used combined medicines are 9 units of amlodiphine and furosemid (39,1%). According to the accuracy and the inaccuracy of the medical usage, the accuracy is 100% and the inaccuracy is 0%.
Literatur Review : Studi Penggunaan Antibiotik Terhadap Pasien Ulkus Diabetikum Yuliana, Dewi; Hasmi, Nur; Lolo, Andi Maulana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.184

Abstract

Diabetic ulcers are open wounds on the surface of the skin due to macroangiopathy complications resulting in vascular insufficiency and neuropathy, and can develop into infections due to the entry of germs or bacteria and the presence of high blood sugar which is a strategic place for the growth of germs so that an amputation can occur if blood sugar is too low. the higher it is. The purpose of this study is to find out how the development of treatment using antibiotics for diabetic ulcer disease. The research method is that this study uses literature reviews, in searching literature sourced from 2 databases (Pubmed and Google Scholar) using keywords according to the theme. In contrast to previous studies, this study focuses on the development of treatment using antibiotics in the latest diabetic ulcer patients. The amount of literature used is 13 journal articles. Where the results showed that conservative treatment such as long-term oral and parenteral antibiotics proved effective in patients with diabetic foot ulcers, negative pressure wound therapy methods, Moist Wound Healing, silver type antimicrobials (ActicoatTM), dressings have proven effective in patients.
Literature Review : Studi Rasionalitas Penggunaan Obat Antidibetes Pada Penyakit Diabetes Melitus Tipe 2 Yang Mengalami Komplikasi Nefropati Yuliana, Dewi; Athifah, Athifah
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.185

Abstract

Diabetes melitus merupakan penyakit yang ditandai dengan peningkatan kadar glukosa dalam darah atau melebihi batas normal. Pada penyakit diabetes melitus yang tidak terkontrol akan menyebabkan terjadinya berbagai komplikasi kronik pada pasien diabetes salah satunya yaitu nefropati diabetik. Tujuan penelitian ini yaitu untuk mengetahui rasionalistas penggunaan obat antidiabetes pada penyakit nefropati diabetik. Adapun metode penelitian yaitu penelitian ini menggunakan literature review, dalam pencarian literatur bersumber dari 2 database (Pubmed dan Google Scholar) menggunakan kata kunci sesuai dengan tema. Berbeda dengan penelitian sebelumnya, pada penelitian ini berfokus pada penggunaan obat antidiabetes pada penyakit nefropati diabetik. Adapun jumlah literatur yang digunakan yaitu sebanyak 3 artikel jurnal. Dimana hasil yang didapatkan bahwa penggunaan obat antidibetes pada penyakit nefropati diabetik yang paling efektif yaitu kombinasi antara AOD dengan insulin seperti obat antidiabetes metformin dengan insulin insulin long-acting (kerja panjang) atau atau rapid-acting (kerja cepat).
Bentuk Sediaan dan Keamanan Penggunaan Tea Tree (Melaleuca alternifolia) Oil dalam Kosmetik Damras, Anggi Aprianti; Mirawati, Mirawati; Hasrawati, Andi
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.193

Abstract

Tea Tree Oil is an essential oil obtained from distillation and has a complexity of active ingredients, a strong aroma, and a natural marketing image that causes it to be frequently used in modern skin care products. This literature study aims to determine the cosmetic dosage form of Tea Tree (Melaleuca alternifolia) Oil and the safety of its use, which was carried out using the article review method using Google Scholar and PubMed as data sources, then journals were selected based on inclusion and exclusion criteria. Relevant articles were selected from as many as 11 articles. The results of the review showed that tea tree oil is widely formulated as a cosmetic preparation in the form of shampoos, toothpaste, hydrogels and bio-polymers with activities as antibacterial, antifungal, antiviral, antiseptic, anti-inflammatory on the skin, and anti-acne. Tea tree oil also shows good safety at certain concentrations, but can also cause allergic reactions.
Aktivitas Antibakteri Ekstrak Metanol Daun Bidara (Ziziphus mauritiana Lam) Terhadap Bakteri Uji Penyebab Luka Infeksi Dengan Metode Difusi Agar Irfanitha, irfanitha; Naid, Tadjuddin; Nuryanti, Siska
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.199

Abstract

Bidara leaves (Ziziphus mauritiana Lam) have the ability as an antibacterial, because they contain chemical compounds such as alkaloids, flavanoids, saponins, tannins and phenols. The content of phytochemical substances in bidara leaves accelerates the wound healing process on the outer skin. This study aims to determine the antibacterial activity of the methanol extract of bidara leaves (Ziziphus mauritiana Lam) against test bacteria that cause infectious wounds using the agar diffusion method. This test began with a screening test using 4 test bacteria and the results were inhibiting the growth of Staphylococcus aureus, Pseudomonas aeruginosa, Staphylococcus epidermidis and Propionibacterium acnes at concentrations of 0.1% and 0.5%. Then tested the antibacterial activity of the methanol extract of bidara leaves (Ziziphus mauritiana Lam) using the agar diffusion method and the result was that the ethanol extract of bidara leaves Ziziphus mauritiana Lam) has strong potential as an antibacterial against the test bacteria with the largest diameter of the inhibition zone at a concentration of 4% of 15 .00mm.
LITERATURE REVIEW: PENGGUNAAN OBAT ANTIBIOTIK PADA PASIEN PNEUMONIA Yuliana, Dewi; A, Miftahul Janna
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.201

Abstract

Pneumonia is an acute inflammatory disease of the lung parenchyma which usually results from an acute lower respiratory tract infection with coughing and shortness of breath. The purpose of this study was to find out how to use antibiotics in pneumonia patients. The research method is that this study uses literature reviews, in searching literature sourced from 2 databases (Pubmed and Google Scholar) using keywords according to the theme. Unlike previous studies, this study focuses on the use of antibiotic drugs in pneumonia patients. The amount of literature used is 13 journal articles
Analisis Kadar Siklamat Pada Selai Yang Beredar Di Perumahan BTP Kota Makassar Dengan Metode Spektrofotometri UV-Vis Andini, Ayu; Widiastuti, Harti; Baits, Muzakkir
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.207

Abstract

Sweeteners are chemical compounds that are widely added and used in various processed food and beverage products, one of which is jam. Jam is a semi-solid food made from fruit or other processed products. Sweeteners consist of natural sweeteners and artificial sweeteners. Cyclamate is one of the artificial sweeteners that is often used in society because it has a sweetness intensity 30 times that of pure sugar. Excessive use of cyclamate can cause negative effects on health such as cancer (carcinogenic), nerve disorders, impaired liver function, stomach irritation and changes in cell function. The maximum limit for using cyclamate in jam according to SNI 01-0222-1995 is 2 g/kg. This study aims to identify and determine the levels of cyclamate in jam circulating in BTP Makassar housing. The type of research used is laboratory observation with simple random sampling technique. This research was conducted qualitatively (TLC and precipitation method) and quantitatively (uv-vis spectrophotometric method). The results of this study indicated that all negative samples contained cyclamate with a standard Rf value of 0.875 for cyclamate.
Analisis Kadar Flavonoid Ekstrak Etanol Cabe Rawit, Cabe Keriting, Dan Cabe Besar Menggunakan Metode Spektrofotometri UV-VIS Fadillah, Nur; Baits, Muzakkir; Maryam, St
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i1.208

Abstract

Chili fruit is a type of medicinal plant which is used as an anti-inflammatory, analgesic, antiflatulant, headache and rheumatism because it contains capsaicin, capsantin, carotenoids, essential alkaloids, resin, volatile oil, multivitamins. This study aims to determine the total flavonoid content of three types of chili using the UV-VIS spectrophotometry method. This type of research is laboratory experimental using a spectrophotometer method based on the determination of extract levels and quarcetin standards. The stages of this study began with sample preparation, extraction of compounds in the sample using ethanol solvent, and ended with the determination of total flavonoid content of the chili fruit sample and quarcetin standard. This study found that the average total flavonoid content for samples of bird's eye chilies, large chilies, and curly chilies was 19.695; 31.72; and 16.011 mg QE/g extract. The percentage of total flavonoid content in bird's eye chilies, large chilies, and curly chilies in this study were 1.9695%; 3.172%; and 1.6011%.

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