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INDONESIA
Indonesian Journal Health Science and Medicine
Published by Universitas Muhammadiyah Sidoarjo
ISSN : -     EISSN : 30638186     DOI : https://doi.org/10.21070/ijhsm
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health Veterinary
Focus: The Indonesian Journal on Health Science and Medicine (IJHSM) focus to advance the field of health science and medicine by publishing high-quality, peer-reviewed research articles, reviews, and case studies. Our journal serves as a platform for researchers, clinicians, and healthcare professionals to share innovative findings, critical insights, and emerging trends in the broad domain of health science and medicine. Scope: Clinical Research and Practice Studies on the diagnosis, treatment, and prevention of diseases. Clinical trials and evidence-based practices. Advances in medical technology and therapeutics. Public Health Epidemiology and health statistics. Health policy and management. Community health initiatives and health education. Biomedical Science Research on cellular and molecular biology. Genetics and genomics. Pharmacology and toxicology. Health Care Systems and Services Health care delivery and management. Quality improvement in health care services. Health economics and health informatics. Global Health Health issues affecting populations worldwide. International health regulations and practices. Global health governance and diplomacy. Health Promotion and Disease Prevention Lifestyle and behavioral interventions. Preventive medicine and early detection. Nutritional science and physical activity. Mental Health Research on mental health disorders and treatments. Psychological well-being and mental health promotion. Integration of mental health services in primary care. Innovations in Health Education and Training Medical and health science education methodologies. Training programs for health professionals. Continuing education and professional development.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 24 Documents
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Search results for , issue "Vol. 1 No. 2 (2024): October" : 24 Documents clear
L-Carnitine Treatment of Adult Rats With Busulfan-Induced Oligospermia Owain, Fahad Saber; Mejbel, Elham Ahmed; Farhan, Rana Salim; Saleh , Eman Naji
Indonesian Journal on Health Science and Medicine Vol. 1 No. 2 (2024): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v1i1.12

Abstract

Abstract. The purpose of this research was to examine the effects of L-carnitine treatment on adult rats that had busulfan-induced oligospermia. In our experiment, we used twenty-one adult male rats, each weighing around 200 g. Three groups of rats were used for the experiments: The first set of subjects, called the control group, had DMSO administered intraperitoneally and 1 mL of pure water gavaged orally once daily. The second group received 20 mg/kg of busulfan (Bus) administered IP once daily along with a daily oral gavage of 1 ml of distilled water. The third set of subjects received a single I.P. of busulfan along with L-carnitine (L-car) and busulfan administered orally. One day after busulfan injection, L-carnitine were administered for a duration of 28 days at 350 mg/kg.bw. After dissecting, the epididymis and testis were meticulously removed and weighed, along with any excess fat and blood. The spermatozoa were taken from the removed caudal epididymis and incubated in PBS medium containing at 37C for 5 minutes, this used for counting and checking abnormalities. MDA and GSH were also estimated in testes tissues by using HPLC. The administration of BU resulted in a substantially testes weight, and relative testes weight (p <.05) as compared to the control group. testes weight, and relative testes weight were all markedly improved with L-carnitine administration as compared to G2. after administering BU, sperm count and motility were significantly lower (p <.05) compared to G1. There was a significant improvement in motility, sperm count, and abnormalities with L-carnitine administration compared to G2. after BU was administered, MDA were considerably higher and GSH significantly lower (p <.05) as compared to G1. The results of measuring oxidative stress indicators were dramatically improved with L-carnitine administration when contrasted with G2. In conclusion, Busulfan may have a negative impact on male fertility if taken alone, but when combined with L-carnitine, the drug's cytotoxic effects can be mitigated, protecting both testis and semen. Highlights: L-carnitine Treatment: Significantly improved testis weight and sperm quality in busulfan-treated rats. Oxidative Stress Reduction: L-carnitine mitigated increased MDA levels and restored GSH in testicular tissue. Fertility Protection: Co-administration of L-carnitine reduced the cytotoxic effects of busulfan on male fertility. Keywords: L-carnitine, busulfan, oligospermia, male fertility, oxidative stress
Hyperactivity Disorders: An Assessment of Kindergarten Teachers' Knowledge: Gangguan Hiperaktif: Penilaian Pengetahuan Guru Taman Kanak-kanak Mutashar, Mohammed Kadhim; Awad, Kadhim Jawad; Atiyah, Maher Abdulameer
Indonesian Journal on Health Science and Medicine Vol. 1 No. 2 (2024): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v1i2.14

Abstract

Background: The symptoms of hyperactivity disorder include unpredictable, involuntary, and inappropriate movements that occur due to organic or psychological factors, as well as attention deficit disorder. Hyperactivity disorder is characterised by physical movements that surpass the normal or acceptable limit. Objective: The aim of the present study is to assess the kindergartens teachers knowledge regarding hyperactivity disorders in children. Methods: This cross-sectional study was carried out at Basrah kindergartens between November 2022 and the start of April 2023. A questionnaire was used to gather data for this study, which involved 60 sample (female) kindergarten instructors. The results were then statistically examined. Results: Sixty percent of the participants in this research were between the ages of 20 and 29. 43.3% possess a diploma in education. Of the participants, 81.7% had not undergone any training courses on hyperactivity condition, and 63.3% have 1–5 years of experience. Conclusion: The study concluded that teachers have adequate knowledge about hyperactivity disorder. Highlights: Hyperactivity disorder causes excessive, involuntary, and inappropriate movements. Assess kindergarten teachers’ knowledge of hyperactivity disorder. Teachers show adequate knowledge, but training is limited. Keywords: Kindergartens, Hyperactivity, Knowledge. Disorder, Teacher, Assessment
Determination of Self-Efficacy Level: The Capacity of Patients with Hypertension to Manage their Chronic Disease: Penentuan Tingkat Efikasi Diri: Kapasitas Pasien Hipertensi untuk Mengelola Penyakit Kronisnya Abbass, Zahraa; Jassim, Saja Kareem; AL-Fayyadh, Sadeq; Hafedh, Sukaina; Tiryag, Ali Malik; AL-Hadrawi, Hayder Hamzah Ali
Indonesian Journal on Health Science and Medicine Vol. 1 No. 2 (2024): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v1i2.15

Abstract

Background: One psychological idea frequently connected to treating chronic illnesses, such as hypertension, is self-efficacy. The objective of this study was to evaluate the ability of hypertensive patients to manage their chronic condition and to determine the link between participants' socio-demographic factors and their self-efficacy in controlling hypertension. Methods: A correlational descriptive design was implemented from October 2022 to March 2024. The study sample was purposive (non-probability), consisting of 171 patients with hypertension. Data were gathered via a Google Form, which includes a socio-demographic data section and the Self-Efficacy for Managing Chronic Disease 6-Item Scale (SES6C). Results: A modest level of self-efficacy among hypertension patients was statistically validated, including 58% of the study population. Equally important, a statistically significant inverse association exists between participants' age and their self-efficacy in controlling hypertension (r = -.250 at p = 0.01). Furthermore, a statistically significant disparity exists in the self-efficacy of hypertension management across gender groups (p-value = .041), age categories (p-value = .000), reading groups (p-value = .032), marital status categories (p-value = .000), follow-up groups (p-value = .000), and exercise groups (p-value = .000). Conclusion: The study's findings indicate a statistically significant difference and link between socio-demographic variables and self-efficacy in treating hypertension. This indicates that self-efficacy in controlling hypertension is a multifaceted notion, and a singular component cannot dictate its trajectory. It is, instead, a result of the interplay of various elements, such as age, gender, experience, and education. Highlights: Assess socio-demographic factors' impact on self-efficacy in hypertension management. Correlational design with 171 hypertensive patients via SES6C scale. Self-efficacy in hypertension control is influenced by diverse socio-demographic factors. Keywords: Self-Efficacy, Hypertension, Chronic Disease, Capacity, Patients
Association Between Venous Thrombosis (VT) and Pregnancy: A Literature Review: Hubungan Antara Trombosis Vena (VT) dan Kehamilan: Sebuah Tinjauan Literatur Dalis, Noor Salman
Indonesian Journal on Health Science and Medicine Vol. 1 No. 2 (2024): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v1i2.16

Abstract

The incidence of VTE varies across countries, with Eastern regions generally reporting lower rates. In pregnancy, a combination of intrinsic factors, such as hormonal changes, increased blood clotting tendency, and genetic predispo-sitions, along with environmental factors like lifestyle and healthcare access, can trigger VTE through various, often overlapping mechanisms. The precise role of certain risk factors and their interactions during pregnancy remains un-clear and warrants further study. Ongoing research into pregnancy-related VTE is crucial due to the considerable number of idiopathic cases and the need to refine risk stratification methods. Understanding how different risk factors interact during pregnancy can lead to more effective prevention strategies and targeted treatments. As new risk factors are identified, they may help clarify the underlying mechanisms of VTE in pregnancy, particularly in cases where the cause is unknown. Additionally, improving risk stratification not only helps prevent the initial occurrence of VTE in pregnant women but also plays a vital role in reducing the likelihood of recurrence, ultimately leading to better out-comes for both the mother and the child, as well as more efficient use of healthcare resources. Highlights: VTE in Pregnancy: Hormonal, genetic, and environmental factors contribute. Research Needs: Clarify interactions, refine risk stratification, prevent idiopathic cases. Outcomes: Better maternal-child health, reduced recurrence, efficient healthcare use. Keywords: Venous thrombosis, Thrombosis, Cerebral Venous Sinus Thrombosis, Coagulation, pregnancy.
Transcriptomic and Metabolomic Differential Responses in Hypoxia on RBL-2H3 Cell Through Sodium Cromoglycate Mediates Naser, Rana Hussein
Indonesian Journal on Health Science and Medicine Vol. 1 No. 2 (2024): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v1i2.17

Abstract

Hypoxia is a state in which sufficient oxygen is not available at the tissue level, a condition that leads to hypoxemia. Mast cells (MCs) are tissue resident cells that are widely distributed in vascularized tissues such as airways and gastrointestinal tract. Previously, studies have established the effect of pre-treatment of MCs with Sodium Cromoglicate (SCG) inhibitor in lung tissues of SD rats. Thus, due to the complexity and less understanding of the cell structure of lung tissues, and in order to understand the changes of MCs under hypoxia, RBL-2H3 were utilized in an experimental in-vitro study that aimed to evaluate the transcriptomic and metabolomic variations of these cells under hypoxic conditions and after pre-treatment with SCG. Differential expression analysis identified 25 genes as differentially expressed between HSCG vs HC group. On KEGG pathway enrichment analysis, Arachidonic acid metabolism, glutathione metabolism and AMPK pathway were among the enriched pathways in the HSCG vs HC group. A total of 1,513 metabolites were identified. These metabolites were amino acids, fatty acids, organic acids, lipids, carbohydrates, and others. Metabolic pathway enrichment analysis revealed that in the HSCG_vs_HC group, Glutathione, Val-Val, Arg-Glu, Pro-Glu and 1-Stearoyl-rac-glycerol were upregulated whereas, Cytidine, Hypoxanthine, Histamine and Pro-Asp were decreased. In conclusion, our study findings reveal that SCG impacts on cell mechanisms under hypoxic conditions.
The Effect of Some Immunological Markers (IgM, IgG, CCP, IL1) Associated with RA in a Sample of Iraqi Patients: Pengaruh Beberapa Penanda Imunologi (IgM, IgG, CCP, IL1) yang Berhubungan dengan RA pada Sampel Pasien Irak Ahmed, Atheer Shehab; Al-Ezee, Ali Shakir; Sahm, Sara Fawzi
Indonesian Journal on Health Science and Medicine Vol. 1 No. 2 (2024): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v1i2.21

Abstract

This work was performed on Iraqi patients with rheumatoid arthritis. It collected blood samples from 60 patients with RA whose ages range between 21-70 years. The study included more females than males, as the former was 55 by 91.7%, while the latter was 5 at 8.3%. To compare, 28 other blood samples were drawn from healthy control participants who range from 21-60 years, and the males was 5, 17.9%. The females were 23 by 82.1%, as the highest was in the ages 41-60 years and 51.7 and the age group (≤20) years (3.3%) was lowest as the disease among non-smokers(90.0%) is the largest in comparison to the rate among smokers (10.0%) with significant differences (P<0.001). The disease among married couples (80.0%) was statistically different (P<0.01) as the largest in reference to the unmarried and (20.0%). A significant rise (P<0.001) in Intreleukin- 1 alpha in patients 2.87 units/ml appeared while in healthy people 1.36 units/ml, and a significant rise "(P<0.001) in cyclic citrullinated peptides antibody in the blood of patients relative to the healthy". Here, the protein in the patients' blood was 406.62 mg/L and the 66.07 mg/L in the healthy. A high significant rise (P<0.001) was seen in immunoglobulin IgG in patients rising to 3.39 (ug/ml) and the healthy 0.72 (ug/ml). A significant rise happened (P<0.001) in the immunoglobulin IgM in patients reaching 8.75 (ug/ml).) compared to the healthy at 5.32 (ug/ml). Highlights: Demographics: RA affects mostly females (91.7%), non-smokers (90%), and married (80%). Biomarkers: Significant increases in IL-1α, CCP antibody, IgG, and IgM in RA. Controls: Healthy controls show lower biomarker levels compared to RA patients. Keywords: Marker, IgM, IgG, CCP, IL1.
Students’ Knowledge Regarding Passive Smoking: A Cross-Sectional Study: Pengetahuan Mahasiswa Mengenai Perokok Pasif: Sebuah Studi Cross-Sectional Hussein, Wathiq Faraon; Rahi, Eman H; Taqi, Riyadh Hussain
Indonesian Journal on Health Science and Medicine Vol. 1 No. 2 (2024): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v1i2.23

Abstract

Background: Worldwide, smoking is a serious public health issue. While thousands of researchers have examined the health impacts of active smoking, less is known about the effects of passive smoking. Objectives: To identify the students’ knowledge regarding passive smoking. Methods: Nursing college students were given an electronic form to complete as part of a cross-sectional study aimed at evaluating their understanding of passive smoking. Convenient electronic sampling was employed. The study included a sample size of 150 University of Basra College of Nursing students at all levels. Results: We estimated that the population was composed of 61.4% Basra residents, 13.3% Thiqar residents, 10% Babylonians, 7.4% Baghdad residents, 6.6% Samawa residents, and 1.3% Dyala residents. 4% were older than 28, 80% were between the ages of 23 and 27, and 16% were between the ages of 18 and 22. They were divided into four stages: 22% in the first, 16% in the second, 18% in the third, and 44% in the fourth. The midnight study accounted for 30% of the sample, whereas the morning study accounted for 70%. Conclusion: Nursing college students are highly knowledgeable about the negative effects of passive smoking, as evidenced by the fact that the majority of the questionnaire's items were significant. Highlights: Smoking is a public health issue; passive smoking effects are under-researched. Assess nursing students' knowledge of passive smoking. Nursing students are knowledgeable about passive smoking's negative effects. Keywords: Students, Knowledge, Passive Smoking
A Review: Diagnosis and Treatment of Monkeypox Patients: Sebuah Tinjauan: Diagnosis dan Pengobatan Pasien Cacar Monyet Hussein, Salwa Hamza; Dakil, ZainabAbd al-azim; Nasser, Batheena Abed alhassan
Indonesian Journal on Health Science and Medicine Vol. 1 No. 2 (2024): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v1i2.24

Abstract

A viral illness impacting children and young adults, it commences gradually and the infection can be minor. A significant proportion of patients progress to the acute stage of the infection. The condition progresses in the acute phase to encephalitis, myocarditis, pneumonia, and ocular complications in severe instances. The monkeypox viral infection constitutes a significant global public health issue. The nation carries the highest burden of monkeypox infections internationally and will significantly contribute to the eradication of this disease worldwide. Despite the country's significant advancements in mitigating monkeypox virus infections in prior years, Iraq currently encounters obstacles in its objective to diminish the fatality and morbidity rates associated with monkeypox. In alignment with the WHO global health sector policy on monkeypox, we emphasise additional priority for action to eradicate this virus in Iraq, aiming to accomplish the objective of lowering death, and we recommend prioritising service coverage targets for diagnosis and treatment. Initially, it is essential to enhance the diagnostic and therapeutic capabilities of medical facilities and healthcare professionals. Secondly, the government must alleviate the financial strain of healthcare on patients. Third, improved coordination of current national initiatives and resources is essential to create an integrated prevention and control system encompassing the prevention, screening, diagnosis, and treatment of HIV infection and monkeypox across the life cycle. Thus, advancement can be achieved in the objective of eradicating monkeypox in Iraq. Highlights: Gradual onset illness affecting children, causing severe complications in acute stage. Iraq faces challenges in reducing monkeypox fatality and morbidity rates. Focus: Enhance healthcare, ease costs, and improve prevention coordination. Keywords: Mpox, Health problem, Infection, Diagnosis and treatment.
Students Attitudes and Hesitancy Toward COVID-19 Vaccine: A Cross-Sectional Study: Sikap dan Keraguan Mahasiswa Terhadap Vaksin COVID-19: Sebuah Studi Cross-Sectional Jassim, Firas A.
Indonesian Journal on Health Science and Medicine Vol. 1 No. 2 (2024): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v1i2.25

Abstract

Background: Recovering from the recent COVID-19 outbreak requires widespread vaccine coverage. Nonetheless, there are worries regarding the effectiveness and safety of this immunization campaign. Objectives: To identify students’ attitudes and hesitancy toward COVID-19 vaccine. Methods: Data for a cross-sectional study with 200 participants from the University of Basrah was gathered using a closed-ended questionnaire. The participants ranged in age from 18 to 58. The study began in November 2021 and ended in April 2022. Utilizing SPSS version 26, the analysis was conducted. Results: According to the report, 84% of those surveyed had received the coronavirus vaccine. The Pfizer vaccine was selected by 73% of them. (61%) of the participants' trust in the vaccine's manufacturer. According to medical studies, 82.5% of participants said they would rather get the vaccine. Conclusion: The negative effects of the immunizations and their administration caused a great deal of anxiety. Social media has a big impact on the decision to get the immunizations. Highlights: Assess students' attitudes and hesitancy toward COVID-19 vaccines. Cross-sectional study with 200 participants; SPSS version 26 analysis. High vaccination rates, Pfizer preference, trust influenced by social media. Keywords: Students, Attitudes, Hesitancy, COVID-19 Vaccine
Outcomes of Dome-Shaped Upper Tibial Osteotomy for Correction of Tibia Vara In Pediatric Age Group A Mid-Term Follow-Up Study: Hasil dari Osteotomi Tibialis Atas Berbentuk Kubah untuk Koreksi Tibia Vara pada Kelompok Usia Anak-Anak: Sebuah Studi Tindak Lanjut Jangka Menengah Al-Khafaji, Aymen Subhi Abbas
Indonesian Journal on Health Science and Medicine Vol. 1 No. 2 (2024): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v1i2.27

Abstract

Aims: To evaluate the outcome of dome-shaped high tibial osteotomy at the end of 24 months of follow up postoperatively using knee society, function score and knee alignment (HKA angel). Patients and methods: A sample of 21 patients (31 knee joints) with bilateral or unilateral genu varum of different etiology that was operated on between 1st. July.2014 - 31st.Dec.2015 in Al-Wasity Teaching Hospital by dome shaped high tibial osteotomy for correction of varus status and followed up for 24 months post-operatively for assessment of outcome of surgery was included in this study. Results: The mean of corrected angel on immediate post-operative assessment was 11.3° ±2.9 SD valgus (range 5–15°). This angle decreased to 6.4°±2.8 SD valgus at 24 months with 4.9° Loss of correction. The mean angel of correction was decreased by 3.1 ° to 9 month and 1.8 degree from 9 month to 24 months of follow up, and this difference concerning angel changes with time was statistically significant (p=0.01).We had 4 patients with unilateral varus due to Blount's disease were under corrected. The outcome as assessed by the knee society and functional score was either excellent or good with all patient's even those who were under correction also showed improvement in these score. No significant complications reported. Highlights: Evaluate dome-shaped high tibial osteotomy outcomes over 24 months. Analyzed 31 knees with genu varum post-osteotomy in 21 patients. Significant correction achieved; excellent/good functional outcomes; minor complications reported. Keywords: genu varum, high tibial osteotomy, knee society score and faction score, HKA angle.

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